Dr Mirella Dottori is an ARC Future Fellow and Group Leader of the Stem Cell Laboratory at the Centre for Neural Engineering, University of Melbourne, Australia. Dr Dottori undertook her PhD at Walter and Eliza Hall Institute in the field of developmental neuroscience. Her studies in this area continued into her postdoctoral training years at the Salk Institute, La Jolla, USA. She then returned to Australia as a NHMRC Howard Florey Fellow and joined Professor Martin Pera’s group at Monash University to study human stem cell biology. In 2007, Dr Dottori established her own research group at the University of Melbourne. Since 2003, Dr Dottori’s research has been within the field of human pluripotent stem cell biology, which is one of the most rapidly advancing areas of medical research. Pluripotent cells can now be generated from human biopsy tissue and this technology allows the possibility of generating patient-specific stem cells for the development of cell replacement strategies as well as genetically appropriate in vitro human cellular models of disease and drug screening platforms. However, in order to achieve these objectives, it is firstly essential to understand how to regulate stem cell differentiation to a defined lineage. The major focus of Dr Dottori’s research is studying human pluripotent stem cells and their differentiation to specific lineages of the central and peripheral nervous system. Her research objectives are to create human cellular models of neural development and neurodegenerative diseases and also to develop stem cell therapies to promote regeneration within the nervous system.
1992 HECS Exemption Scholarship for Honours, University of Melbourne
1993 - 1996 Australian Postgraduate Research Scholarship
1999 - 2001 Human Frontiers Science Program Organization (International)
Long-Term Postdoctoral Fellowship
2003 - 2005 NHMRC Howard Florey Centenary Fellowship