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A/PROF Christopher Davey

Positions

Honorary, Psychiatry
Academic, Centre for Youth Mental Health

Publications

Selected publications

2019
- Journal Articles
  - Aripiprazole compared with placebo for auditory verbal hallucinations in youth with borderline personality disorder: Protocol for the VERBATIM randomized controlled trial.. Early Intervention in Psychiatry. 2019
  - Early intervention for bipolar disorder - Do current treatment guidelines provide recommendations for the early stages of the disorder?. Journal of Affective Disorders. 257. 2019
  - Improving functional outcomes in early-stage bipolar disorder: The protocol for the REsearch into COgnitive and behavioural VERsatility trial.. Early Intervention in Psychiatry. 2019
  - Neuroimaging predictors of onset and course of depression in childhood and adolescence: A systematic review of longitudinal studies. 2019
  - The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): a randomised, double-blind, placebo-controlled, multicentre clinical trial. The Lancet Psychiatry. 6. 2019
  - The case for improved care and provision of treatment for people with first-episode mania.. The Lancet Psychiatry. 2019
- Journal Articles Refereed
  - "Some guidance and somewhere safe": Caregiver and clinician perspectives on service provision for families of young people experiencing serious suicide ideation and attempt. Clinical Psychologist. 23. 2019
  - Broad clinical high-risk mental state (CHARMS): Methodology of a cohort study validating criteria for pluripotent risk. Early Intervention in Psychiatry. 13. 2019
  - Factors associated with vocational disengagement among young people entering mental health treatment. Early Intervention in Psychiatry. 13. 2019
  - Neurodevelopmental correlates of the emerging adult self. Developmental Cognitive Neuroscience: a journal for cognitive, affective and social developmental neuroscience. 36. 2019
  - No Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis. 2019
  - Vocational engagement among young people entering mental health treatment compared with their general population peers. Early Intervention in Psychiatry. 13. 2019
- Journal Articles Unrefereed Letters or Notes
  - Early intervention for depression in young people: a blind spot in mental health care. The Lancet Psychiatry. 6. 2019
  - Early intervention for depression in young people: a blind spot in mental health care Reply. The Lancet Psychiatry. 6. 2019
- Conference Proceedings
  - Manic or labile mood symptoms predict antidepressant associated suicidality among depressed youth. Bipolar Disorders. 2019
2018
- Journal Articles Refereed
  - A Comparison of Vocational Engagement Among Young People with Psychosis, Depression and Borderline Personality Pathology. Community Mental Health Journal. 54. 2018
  - Integrating family work into the treatment of young people with severe and complex depression: a developmentally focused model. Early Intervention in Psychiatry. 12. 2018
  - Ketamine and rapidly acting antidepressants: Breaking the speed of sound or light?. Australian and New Zealand Journal of Psychiatry. 52. 2018
  - Moderated online social therapy for depression relapse prevention in young people: pilot study of a "next generation' online intervention. Early Intervention in Psychiatry. 12. 2018
  - Pre-onset risk characteristics for mania among young people at clinical high risk for psychosis. Schizophrenia Research. 192. 2018
  - Predictors and consequences of health anxiety symptoms: a novel twin modeling study. Acta Psychiatrica Scandinavica. 137. 2018
  - Self and other body perception in anorexia nervosa: The role of posterior DMN nodes. The World Journal of Biological Psychiatry. 19. 2018
  - Three Nontraditional Approaches to Improving the Capacity, Accessibility, and Quality of Mental Health Services: An Overview. Psychiatric Services. 69. 2018
  - Ventromedial prefrontal cortex activity and pathological worry in generalised anxiety disorder. British Journal of Psychiatry. 213. 2018
  - Youth Codesign of a Mobile Phone App to Facilitate Self-Monitoring and Management of Mood Symptoms in Young People With Major Depression, Suicidal Ideation, and Self-Harm 2018
  - Youth Depression Alleviation-Augmentation with an anti-inflammatory agent (YoDA-A): protocol and rationale for a placebo-controlled randomized trial of rosuvastatin and aspirin. Early Intervention in Psychiatry. 12. 2018
- Journal Articles Unrefereed Letters or Notes
  - The brain's center of gravity: how the default mode network helps us to understand the self. World Psychiatry. 17. 2018
- Other Refereed Contribution to Refereed Journals
  - A clinician's quick guide to evidence-based approaches: Managing suicide risk in young people. Clinical Psychologist. 22. 2018
2017
- Journal Articles Refereed
  - A Brain Model of Disturbed Self-Appraisal in Depression. American Journal of Psychiatry. 174. 2017
  - A systematic review and meta-analysis of prospective transition from major depression to bipolar disorder. Acta Psychiatrica Scandinavica. 135. 2017
  - Comprehensive Online Self-Monitoring to Support Clinicians Manage Risk of Suicide in Youth Depression A Pilot Study. Crisis: the journal of crisis intervention and suicide prevention. 38. 2017
  - Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry. 22. 2017
  - Ethical considerations in preventive interventions for bipolar disorder. Early Intervention in Psychiatry. 11. 2017
  - Hard to look on the bright side: neural correlates of impaired emotion regulation in depressed youth. Social Cognitive and Affective Neuroscience. 12. 2017
  - Human ventromedial prefrontal cortex and the positive affective processing of safety signals. Neuroimage. 152. 2017
  - Novel biotherapies are needed in youth mental health. Australasian Psychiatry. 25. 2017
  - Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: a 7-year longitudinal study. Translational Psychiatry. 7. 2017
  - Social and academic premorbid adjustment domains predict different functional outcomes among youth with first episode mania. Journal of Affective Disorders. 219. 2017
  - The Depressed Brain: An Evolutionary Systems Theory. Trends in Cognitive Sciences. 21. 2017
  - The Youth Mood Clinic: an innovative service for the treatment of severe and complex depression. Australasian Psychiatry. 25. 2017
- Journal Articles Unrefereed Letters or Notes
  - The effects of stress-tension on depression and anxiety symptoms: evidence from a novel twin modelling analysis (vol 46, pg 3213, 2016). Psychological Medicine. 47. 2017
2016
- Journal Articles Refereed
  - Brain Functional Correlates of Emotion Regulation Across Adolescence and Young Adulthood. Human Brain Mapping. 37. 2016
  - Feelings of shame, embarrassment and guilt and their neural correlates: A systematic review. Neuroscience and Biobehavioral Reviews. 71. 2016
  - Mapping the self in the brain's default mode network. Neuroimage. 132. 2016
  - Neurodevelopmental correlates of proneness to guilt and shame in adolescence and early adulthood. Developmental Cognitive Neuroscience: a journal for cognitive, affective and social developmental neuroscience. 19. 2016
  - The effects of stress-tension on depression and anxiety symptoms: evidence from a novel twin modelling analysis. Psychological Medicine. 46. 2016
  - The unfulfilled promise of the antidepressant medications. Medical Journal of Australia. 204. 2016
  - The unfulfilled promise of the antidepressant medications. Medical Journal of Australia. 204. 2016
  - Youth depression alleviation: the Fish Oil Youth Depression Study (YoDA-F): A randomized, double-blind, placebo-controlled treatment trial. Early Intervention in Psychiatry. 10. 2016
- Conference Proceedings
  - Beyond Psychosis Risk: Introduction to a Broad at Risk Mental State. Early Intervention in Psychiatry. 2016
  - Mapping the self in depression. Bipolar Disorders. 2016
  - Predictors of Early Transition from Major Depression to Bipolar Disorder and the Implication for Prevention. Early Intervention in Psychiatry. 2016
  - Symptoms and syndromes prior to the onset of bipolar disorder: findings from a 4 to 13-year longitudinal study. Bipolar Disorders. 2016
  - Understanding hypochondriasis: a novel twin study model of potential causal relationships with anxiety and OC-related disorder symptoms. European Neuropsychopharmacology. 2016
  - Ventromedial Prefrontal Cortex Function, Safety Learning, and Generalised Anxiety Disorder. Biological Psychiatry. 2016
2015
- Journal Articles
  - Back to basics: Could behavioural therapy be a good treatment option for youth depression? A critical review. Early Intervention in Psychiatry. 9. 2015
- Journal Articles Refereed
  - A Neural Mediator of Human Anxiety Sensitivity. Human Brain Mapping. 36. 2015
  - Abnormal Social Reward Responses in Anorexia Nervosa: An fMRI Study. PLoS One. 10. 2015
  - Back to basics: could behavioural therapy be a good treatment option for youth depression? A critical review. Early Intervention in Psychiatry. 9. 2015
  - Comparing three forms of early intervention for youth with borderline personality disorder (the MOBY study): study protocol for a randomised controlled trial. Trials. 16. 2015
  - Cortico-limbic network abnormalities in individuals with current and past major depressive disorder. Journal of Affective Disorders. 173. 2015
  - Developing a roadmap for the translation of e-mental health services for depression. Australian and New Zealand Journal of Psychiatry. 49. 2015
  - Functional brain-imaging correlates of negative affectivity and the onset of first-episode depression. Psychological Medicine. 45. 2015
  - Instruments that prospectively predict bipolar disorder - A systematic review. Journal of Affective Disorders. 179. 2015
  - Mapping the relationship between subgenual cingulate cortex functional connectivity and depressive symptoms across adolescence. Social Cognitive and Affective Neuroscience. 10. 2015
  - Prospective progression from high-prevalence disorders to bipolar disorder: Exploring characteristics of pre-illness stages. Journal of Affective Disorders. 183. 2015
  - Specific functional connectivity alterations of the dorsal striatum in young people with depression. NeuroImage: Clinical. 7. 2015
- Conference Proceedings
  - Generalized anxiety disorder is characterised by a non-discriminative response of the ventromedial prefrontal cortex during fear learning. European Neuropsychopharmacology. 2015
2014
- Journal Articles Refereed
  - Development of practice principles for the management of ongoing suicidal ideation in young people diagnosed with major depressive disorder. 2014
  - Extremely preterm birth and adolescent mental health in a geographical cohort born in the 1990s. Psychological Medicine. 44. 2014
  - Functional brain imaging studies of youth depression: A systematic review. NeuroImage: Clinical. 4. 2014
  - Online and social networking interventions for the treatment of depression in young people: a systematic review.. Journal of Medical Internet Research. 16. 2014
  - The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): study protocol for a randomised control trial. Trials. 15. 2014
- Conference Proceedings
  - Functional Connectivity of the Subgenual Anterior Cingulate Cortex Predicts Emerging Depressive Symptoms Between Mid and Late Adolescence. Biological Psychiatry. 2014
  - The Structure of Negative Mood States: Evidence from a Novel Twin Study Analysis. Biological Psychiatry. 2014
2013
- Journal Articles Refereed
  - Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness. BMC Medicine. 11. 2013
  - Treatment of bipolar depression. Medical Journal of Australia. 199. 2013
  - Treatment of bipolar depression. Medical Journal of Australia. 199. 2013
2012
- Journal Articles Refereed
  - Adolescents' depressive symptoms moderate neural responses to their mothers' positive behavior. Social Cognitive and Affective Neuroscience. 7. 2012
  - Brain functional connectivity during induced sadness in patients with obsessive-compulsive disorder. Journal of Psychiatry and Neuroscience. 37. 2012
  - Meta-analysis of volumetric abnormalities in cortico-striatal-pallidal-thalamic circuits in major depressive disorder. Psychological Medicine. 42. 2012
  - Regionally specific alterations in functional connectivity of the anterior cingulate cortex in major depressive disorder. Psychological Medicine. 42. 2012
  - Regionally specific alterations in functional connectivity of the anterior cingulate cortex in major depressive disorder. 2012
  - Task-related deactivation and functional connectivity of the subgenual cingulate cortex in major depressive disorder.. Frontiers in Psychiatry. 3. 2012
- Journal Articles Unrefereed
  - The treatment of depression in young people. In-Psych. 34. 2012
- Conference Proceedings
  - Increased Rates of Adhd but not Other Psychiatric Disorders in Adolescents Born Extremely Low Birthweight (elbw; < 1000g) or Extremely Preterm (ep; < 28 Weeks): An 18-Year Follow-Up Study. Biological Psychiatry. 2012
2011
- Journal Articles Refereed
  - Increased Amygdala Response to Positive Social Feedback in Young People with Major Depressive Disorder. Biological Psychiatry. 69. 2011
  - Prevalence of psychiatric diagnoses in preterm and full-term children, adolescents and young adults: a meta-analysis. Psychological Medicine. 41. 2011
2010
- Journal Articles Refereed
  - Being Liked Activates Primary Reward and Midline Self-Related Brain Regions. Human Brain Mapping. 31. 2010
  - Fronto-striatal correlates of impaired implicit sequence learning in major depression: An fMRI study. Journal of Affective Disorders. 125. 2010
2008
- Journal Articles Refereed
  - The emergence of depression in adolescence: Development of the prefrontal cortex and the representation of reward. Neuroscience and Biobehavioral Reviews. 32. 2008
2007
- Journal Articles Unrefereed
  - A possible behavioural and cognitive phenotype for the 47,XYY karyotype in a pre-pubertal child. Australasian Psychiatry. 15. 2007
1996
- Journal Articles
  - Alcohol and glucose metabolism in skeletal muscles in the rat. Addiction Biology. 1. 1996

Research

Investigator on

Contract
- UNDERSTANDING THE NEURAL BASIS OF THE EXPERIENCE OF MORAL EMOTIONS IN ADOLESCENTS DEPRESSION administered by Psychiatry 2013 - 2014
Grant
- A NEURAL SYSTEMS MODEL OF FEAR DYSREGULATION IN ANXIETY DISORDERS (Project Grants) awarded by NHMRC 2019 - 2022
- A RANDOMISED CONTROLLED TRIAL OF LOW-DOSE KETAMINE IN YOUTH WITH SEVERE DEPRESSION AND ELEVATED SUICIDE RISK (Project Grants) awarded by NHMRC 2018 - 2021
- A BRAIN-BASED MODEL OF ANXIETY SENSITIVITY IN PANIC DISORDER (Project Grants) awarded by NHMRC 2018 - 2020
- Uncovering heterogeneity of youth depression using neuroimaging-based normative models (Early Career Researcher Grants Scheme) awarded by UNIVERSITY OF MELBOURNE 2017
- PREDICTING TREATMENT RESPONSE IN YOUTH DEPRESSION WITH BRAIN IMAGING (Project Grants) awarded by NHMRC 2014 - 2018
- REFINING TREATMENT STRATEGIES FOR YOUTH DEPRESSION (Career Development Fellowships) awarded by NHMRC 2014 - 2017
- OPTIMISING EARLY INTERVENTIONS FOR YOUNG PEOPLE WITH EMERGING MOOD DISORDER (Centres of Research Excellence) awarded by NHMRC 2013 - 2018
- PROOF OF PRINCIPLE OF THE INFLAMMATORY AND OXIDATIVE THEORY OF DEPRESSION: A TREATMENT STUDY (Project Grants) awarded by DEAKIN UNIVERSITY 2012 - 2018
- First-Line Management of Youth Depression (Project Grants) awarded by NHMRC 2012 - 2016
- USING A NOVEL PARADIGM TO UNDERSTAND THE NEURAL MECHANISMS OF REJECTION SENSITIVITY IN ADOLESCENT DEPRESSION (ORYGEN PORTION) (Young Investigator Award) awarded by NARSAD 2012 - 2016
- A Brain-Based Measure of Anxiety Sensitivity (Project Grants) awarded by NHMRC 2012 - 2014
- Predicting Antidepressant Response in Young People with Depression (Early Career Researcher Grants Scheme) awarded by UNIVERSITY OF MELBOURNE 2011 -
- The self and social engagement in young people with depression and at high risk of depression. (Training (Postdoctoral) Fellowships) awarded by NHMRC 2010 - 2014
- FIRST EPISODE DEPRESSION IN YOUNG PEOPLE: AN FMRI STUDY OF RESPONSES TO IMMEDIATE AND DELAYED, SOCIAL AND NON-SOCIAL REWARDS. (Neuro Science Research Grants) awarded by PFIZER AUST PTY LTD 2008

Awards

Education and training

PhD, University of Melbourne
MPsychiatry, University of Melbourne
MBBS (Hons), The University of Western Australia

Awards and honors

Fellow of the Royal Australian and New Zealand College of Psychiatrists, 2008

Supervision

Available for supervision

Y

Contact Details
- c.davey@unimelb.edu.au
Graduate Study
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