My laboratory investigates how insulin and the related insulin-like growth factors signal into cells.
Insulin is the primary hormone that controls sugar uptake from the blood and its subsequent metabolism. Insulin-like growth factors are involved in normal human growth. Defects in signalling by insulin and/or insulin-like growth factors are associated with type I and type 2 diabetes as well as with cancer and Alzheimer's disease.
Our aim is to use the knowledge we generate to develop new therapeutics to treat these diseases.