PROF Stephen Nutt

PROF Stephen Nutt

Positions

  • Control of gene regulation in the immune system

Overview

OverviewText1

  • www.wehi.edu.au/people/stephen-nutt

    My laboratory studies how the development of immune cells is controlled. This process is critical to protect us against the many potentially harmful micro-organisms in the environment. Developing immune cells have many decisions to make, from deciphering the early signals that initiate their formation from rare blood stem cells, through to strategic responses in the body about whether to ignore or attack foreign organisms. These decisions are important as errors in the immune system result in diseases such as autoimmunity and leukaemia. 

    My research aims to decipher how these cellular decisions are made and the consequences for our protective immunity.   

Publications

Selected publications

Awards

Education and training

  • PhD, University of Vienna
  • BSc(Hons), University of Sydney

Awards and honors

  • Fellow of the Australian Academy of Science, 2016

Supervision

Available for supervision

  • Y

Supervision Statement

  • Research interest

    My laboratory studies the lineage-defining transcription factors that control the development and function of the immune system. Deregulated expression or function of these transcriptional regulators results in autoimmunity and malignancies such as leukaemia and multiple myeloma.

    Specific research interests include:

    - How progenitors undergo commitment to particular cellular fates

    - Deciphering the gene regulatory network controlling late B cell differentiation

    - Understanding the programming of the dendritic cell diversity Defining the genetic program and function of helper T cell subsets