Member of
- RACI Peptide User Group. Committee Member 2015 -
- RACI Women in Chemistry Group. Committee Member 2015 -
- Royal Australian Chemical Institute (RACI). general membership 2007 -
DR Susan Northfield
Positions
- Academic, Pharmacology and Therapeutics
- Academic, Pharmacology and Therapeutics
- Design and synthesis of peptide and peptidomimetic pharmaceuticals (peptide; disulfide-rich; scaffolds)
Affiliation
Publications
Selected publications
2018
Journal Articles Refereed
- Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV-1 Integrase. ChemMedChem. 13. 2018
- Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in the Brain. Journal of Neuroscience. 38. 2018
2016
Journal Articles Refereed
- Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold. European Journal of Medicinal Chemistry. 109. 2016
2015
Journal Articles Refereed
- Effects of Cyclization on Peptide Backbone Dynamics. Journal of Physical Chemistry B. 119. 2015
- Exploring experimental and computational markers of cyclic peptides: Charting islands of permeability. European Journal of Medicinal Chemistry. 97. 2015
- Propargyloxyproline Regio- and Stereoisomers for Click-Conjugation of Peptides: Synthesis and Application in Linear and Cyclic Peptides. Australian Journal of Chemistry. 68. 2015
2014
Journal Articles Refereed
- Disulfide-rich macrocyclic peptides as templates in drug design. European Journal of Medicinal Chemistry. 77. 2014
- Native peptide folding dominates over stereoelectronic effects of prolyl hydroxylation in loop 5 of the macrocyclic peptide kalata B1. Tetrahedron. 70. 2014
- Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds. Angewandte Chemie - International Edition. 53. 2014
- Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients. Proceedings of the National Academy of Sciences of the United States of America. 111. 2014
- Translational Diffusion of Cyclic Peptides Measured Using Pulsed-Field Gradient NMR. Journal of Physical Chemistry B. 118. 2014
Major Reference Works
- Cyclotide Analysis. Edition. 3 2014
2010
Journal Articles Refereed
- Synthesis of "Difficult" Fluorescence Quenched Substrates of Granzyme C. International Journal of Peptide Research and Therapeutics. 16. 2010
2007
Journal Articles
- Lipophilicity of beta-adrenocepter antagonists: A new classification scheme for clinical use. Journal of Pharmacy Practice and Research. 37. 2007
Conference Proceedings
Research
Investigator on
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Grant
- Developing novel BDNF-mimetics as potential treatment for multiple sclerosis (Early Career Researcher Grants Scheme) awarded by UNIVERSITY OF MELBOURNE 2016 - 2017
- Towards new drugs for multiple sclerosis (Science & Medicine Grants) awarded by THE CASS FOUNDATION LTD 2016 - 2017
- Towards new drugs for multiple sclerosis: Synthetic strategies for the synthesis of novel peptide BDNF-mimetics (Incubator Grant) awarded by MULTIPLE SCLEROSIS RESEARCH AUSTRALIA LTD 2016
Additional Grant Information
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Melbourne Neuroscience Institute Fellowship (2017)
Multiple Sclerosis Research Association, Project Grant, CIB, (2017 - 2019)
Melbourne Neuroscience Institute Seed Funding, CIB, (2017)
Awards
Education and training
- PhD, Monash University
- BMedChem (Hons), Monash University
Awards and honors
- 2017 Melbourne Neuroscience Institute Postdoctoral Fellowship, Melbourne Neuroscience Institute, 2017
Supervision
Available for supervision
- Y
- Contact Details
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susan.northfield@unimelb.edu.au
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8344 8304
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Location
- Level: Room:, Medical Building, Parkville
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- Graduate Study
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