DR Holly Cate

DR Holly Cate


  • Demyelinating Disease (Multiple Sclerosis)
  • Nervous System Repair (Neural precursor cells)



  • Dr. Holly Cate is the head of the Myelin Repair Laboratory within the Multiple Sclerosis Research Group located at the Centre for Neuroscience and the Howard Florey Institute.  She completed her PhD in the USA in 2001 where she investigated the development, functional organization and regeneration of invertebrate chemosensory systems.  Following completion of her PhD, she moved to Australia and was awarded a NHMRC Peter Doherty Training fellowship (2003-2006) to undertake a post-doctoral position at the Walter & Eliza Hall Institute, Melbourne.  In 2003, she moved to the Howard Florey Institute (HFI) and helped establish the Multiple Sclerosis Group lead by Prof. Trevor Kilpatrick. She established for the group the use of laser capture microdissection to isolate small brain areas for microarray analysis and led collaboration with Prof. Gary Egan (Neuroimaging, UniMelb & HFI) investigating the MRI parameters for resolving myelin damage, axonal damage, and oedema in mouse models of demyelinating disease.  She also headed contractual research collaborations with Dr. Brank Mitrovik (Berlex) and Dr. Victoria Perreau (Uni Melb), investigating the profile of genes expressed in adult brain stem cells in response to central demyelination. In 2007, she joined the Centre for Neuroscience, University of Melbourne and was awarded a William Collie Fellowship (2007-2009) to investigate molecular mechanisms in the regenerative response to central demyelination while maintaining her link to the HFI as an honorary fellow. Since this time, Dr. Cate has successfully obtained research funding through NHMRC and the University of Melbourne Early Career Researcher Scheme.

    Dr. Cate has served on the Postgraduate Matters Committee (HFI), Postgraduate Student/Mentor Scheme Mentor (HFI), and Judging Panel for Annual Student presentations (HFI) from 2004-2007.  In 2004, she was selected for the Early Career Researcher Development Program, Uni Melb a   


Member of

  • Australian Neuroscience Society. Member 2001 -
  • Society for Neuroscience. Melbourne, Australia, Chapter Representative 1996 -


Selected publications


Investigator on

Additional Grant Information

  • William Collie Fellowship, University of Melbourne (2007-2009)   


Education and training

  • PhD, Georgia State University 2001
  • MSc, University of North Carolina 1996
  • BSc, University of North Carolina 1993

Awards and honors

  • Eureka Prize for Medical Research (awarded to MS Group), 2008
  • Peter Doherty Fellowship, National Health and Medical Research Council (NHMRC), 2003



Available for supervision

  • Y