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Prof

Heather Young

Honorary
Anatomy And Neuroscience
Developmental neurobiology
science & technology
life sciences & biomedicine
animals
neurons
mice
enteric nervous system
neurosciences & neurology
neurosciences
Heather Young's Profile Picture
Prof

Heather Young

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Neuroscience
Heather Young's Profile Picture
Prof

Heather Young

 
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Heather's  Short Profile
 

Heather Young received her PhD in Zoology in 1989 from the University of Melbourne. Her first postdoctoral position was at the Vision, Touch and Hearing Research Centre at the University of Queensland in the laboratory of Dr David Vaney where she examined retinal circuitry.

Her second postdoctoral position was in the laboratory of Prof John Furness at the University of Melbourne, where she used electron microscopy to examine circuitry within the enteric nervous system. After being awarded an NHMRC RD Wright Fellowship in 1994, she started an independent laboratory and switched to enteric nervous system development. She was awarded an NHMRC Fellowship in 1997, and promoted to Senior Research Fellow in 2001. Prof Young's current research is focused on the mechanisms controlling the development of the enteric nervous system and the potential of cell therapy for treating enteric neuropathies.

Projects

Displaying the 10 most recent projects by Heather Young.

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SUPER RESOLUTION CONFOCAL MICROSCOPY FACILITY

This project aims to establish a super-resolution confocal microscopy facility with unrivalled resolution, sensitivity and speed. The widesp..

2016 - 2016
Completed
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CELL THERAPY FOR ENTERIC NEUROPATHIES - THE ESSENTIAL NEXT STEPS

Gastrointestinal motility disorders caused by damage or diseased neurons in the gut wall ("enteric neuropathies) are some of the most clinic..

2015 - 2018
Completed
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Neural migration: Which cells advance and which stay behind?

This project aims to examine the neural crest cells that colonise the developing gut and to identify why some cells advance while others sta..

2015 - 2017
Completed
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DIFFERENTIATION AND FATE IN THE DEVELOPING SYMPATHETIC GANGLIA

This project seeks to understand how a small number of founder cells can divide and differentiate into the myriad different types of cells t..

2014 - 2017
Completed
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Manipulation of enteric neural stem cells for cell therapy to treat enteric neuropathies

Cell therapy offers great promise for the treatment of motility disorders due to defects in the nerve cells in the bowel. Patient-derived ce..

2013 - 2016
Completed
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Wiring the gut's nervous system: formation and maturation of synapses

This project aims to determine how nerve circuits controlling intestinal functions develop; specifically how communication between specific ..

2013 - 2016
Completed
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Role of kinesin binding protein and spontaneous activity in the development of enteric neurons

The nerve cells in the wall of the gut play an essential role in motility. Defects in the development of these nerve cells results in pediat..

2013 - 2016
Completed
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Altered gastrointestinal function in the neuroligin-3 mouse model of autism

2012 - 2014
Completed
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Altered gastrointestinal function in the neuroligin-3 mouse model of autism

2012 - 2014
Completed
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Altered gastrointestinal function in the neuroligin-3 mouse model of autism

2012 - 2014
Completed

26

Projects

Project Types

24

Research Grant

2

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works by Heather Young.

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Role of JNK, MEK and adenylyl cyclase signalling in speed and directionality of enteric neural crest-derived cells

Marlene M Hao, Annette J Bergner, TH Nguyen Huynh, Paige Dissanayake, Laura E Burnett, C Danielle Hopkins, Kevin Zeng, Heather M Young, Lincon A Stamp

Journal article  |  2019  |  Developmental Biology

BACKGROUND: Cells derived from the neural crest colonize the developing gut and give rise to the enteric nervous system. The rate ..

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Technologies for Live Imaging of Enteric Neural Crest-Derived Cells.

Marlene M Hao, Annette J Bergner, Donald F Newgreen, Hideki Enomoto, Heather M Young

Journal article  |  2019  |  Methods in molecular biology (Clifton, N.J.)

Time-lapse imaging of gut explants from embryonic mice in which neural crest-derived cells express fluorescent proteins allows the..

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Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death (vol 6, 2017)

Caroline S Hirst, Lincon A Stamp, Annette J Bergner, Marlene M Hao, Mai X Tran, Jan M Morgan, Matthias Dutschmann, Andrew M Allen, George Paxinos, Teri M Furlong, Sonja J McKeown, Heather M Young

Journal article  |  2018  |  SCIENTIFIC REPORTS

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Development of the Enteric Nervous System

HM Young, LA Stamp, T Uesaka, MM Hao, DF Newgreen, H Enomoto

Book Chapter  |  2018

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Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death

Caroline S Hirst, Lincon A Stamp, Annette J Bergner, Marlene M Hao, Mai X Tran, Jan M Morgan, Matthias Dutschmann, Andrew M Allen, George Paxinos, Teri M Furlong, Sonja J McKeown, Heather M Young

Journal article  |  2017  |  SCIENTIFIC REPORTS

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Spontaneous calcium waves in the developing enteric nervous system

Marlene M Hao, Annette J Bergner, Caroline S Hirst, Lincon A Stamp, Franca Casagranda, Joel C Bornstein, Werend Boesmans, Pieter Vanden Berghe, Heather M Young

Journal article  |  2017  |  Developmental Biology

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Optogenetic Demonstration of Functional Innervation of Mouse Colon by Neurons Derived From Transplanted Neural Cells

Lincon A Stamp, Rachel M Gwynne, Jaime PP Foong, Alan E Lomax, Marlene M Hao, David I Kaplan, Christopher A Reid, Steven Petrou, Andrew M Allen, Joel C Bornstein, Heather M Young

Journal article  |  2017  |  Gastroenterology

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Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System

Sonja J McKeown, Mitra Mohsenipour, Annette J Bergner, Heather M Young, Lincon A Stamp

Journal article  |  2017  |  STEM CELL REPORTS

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Recent advances in regenerative medicine to treat enteric neuropathies: use of human cells

LA Stamp, HM Young

Journal article  |  2017  |  Neurogastroenterology & Motility

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White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies

Alan J Burns, Allan M Goldstein, Donald F Newgreen, Lincon Stamp, Karl-Herbert Schaefer, Marco Metzger, Ryo Hotta, Heather M Young, Peter W Andrews, Nikhil Thapar, Jaime Belkind-Gerson, Nadege Bondurand, Joel C Bornstein, Wood Yee Chan, Kathryn Cheah, Michael D Gershon, Robert O Heuckeroth, Robert MW Hofstra, Lothar Just, Raj P Kapur, et al.

Journal article  |  2016  |  Developmental Biology

142

Scholarly Works

Keyword Analysis

Neurosciences
Clinical (organs, Diseases and Abnormal Conditions)
Clinical Health (organs, Diseases and Abnormal Conditions)
Clinical Sciences
Expanding Knowledge
Biochemistry and Cell Biology
Paediatrics and Reproductive Medicine
Medical Biotechnology
Genetics
Medicinal and Biomolecular Chemistry

News

Displaying the 1 most recent news article by Heather Young.

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Guiding gut nerves home

Heather Young, Lincon Stamp

March 27, 2017

1

News Articles

Honours, Awards and Fellowships

2002

Janssen Award for Basic or Clnical Research in Digestive Sciences

1

Award

Credentials

Positions

Positions

Honorary Supervisor

Anatomy And Neuroscience

It Access

Anatomy And Neuroscience

Member

Australian Society for Cell and Developmental Biology

Member

Gastroenterological Society of Australia

Member

Australian Neuroscience Society

Education

Education

Bachelor of Science

University of Melbourne

Doctor of Philosophy

University of Melbourne

Links

Links