Glenn Wadley

Exercise improves metabolic function and alters the microbiome in rats with gestational diabetes

Dayana Mahizir, Jessica F Briffa, Jennifer L Wood, Kristina Anevska, Elisa L Hill-Yardin, Andrew J Jefferies, Sogand Gravina, Gisella Mazzarino, Ashley E Franks, Karen M Moritz, Glenn D Wadley, Mary E Wlodek

Journal article  |  2020  |  The FASEB Journal

Gestational diabetes mellitus (GDM) is a common pregnancy complication, particularly prevalent in obese women. Importantly, exerci..

Sodium citrate ingestion protocol impacts induced alkalosis, gastrointestinal symptoms, and palatability

Charles S Urwin, Rodney J Snow, Liliana Orellana, Dominique Condo, Glenn D Wadley, Amelia J Carr

Journal article  |  2019  |  Physiological Reports

To compare the effect of 500 mg·kg-1 body mass (BM) sodium citrate ingested in solution or capsules on induced alkalosis, gastroin..

Noncoding RNAs regulating cardiac muscle mass

Glenn D Wadley, Severine Lamon, Sarah E Alexander, Julie R McMullen, Bianca C Bernardo

Journal article  |  2019  |  Journal of Applied Physiology

Non-coding RNAs, including miRNAs, lncRNAs and circRNAs play roles in the development and homeostasis of nearly every tissue of th..

Modest changes to glycemic regulation are sufficient to maintain glucose fluxes in healthy young men following overfeeding with a habitual macronutrient composition

Dale J Morrison, Greg M Kowalski, Clinton R Bruce, Glenn D Wadley

Journal article  |  2019  |  American Journal of Physiology-Endocrinology and Metabolism

Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trial

Shaun A Mason, Bodil Rasmussen, Luc JC van Loon, Jo Salmon, Glenn D Wadley

Journal article  |  2019  |  Diabetes, Obesity and Metabolism

Fetal growth restriction shortens cardiac telomere length, but this is attenuated by exercise in early life

SA Booth, GD Wadley, FZ Marques, ME Wlodek, FJ Charchar

Journal article  |  2018  |  Physiological Genomics

Mitochondrial regulation in skeletal muscle: A role for non-coding RNAs?

Jessica Silver, Glenn Wadley, Severine Lamon

Journal article  |  2018  |  Experimental Physiology

Measurement of postprandial glucose fluxes in response to acute and chronic endurance exercise in healthy humans

Dale J Morrison, Greg M Kowalski, Eleonora Grespan, Andrea Mari, Clinton R Bruce, Glenn D Wadley

Journal article  |  2018  |  American Journal of Physiology-Endocrinology and Metabolism

Effects of breaking up sitting on adolescents' postprandial glucose after consuming meals varying in energy: a cross-over randomised trial

Elly A Fletcher, Jo Salmon, Sarah A McNaughton, Liliana Orellana, Glenn D Wadley, Clinton Bruce, Paddy C Dempsey, Kathleen E Lacy, David W Dunstan

Journal article  |  2018  |  Journal of Science and Medicine in Sport

F2 Fetal Nephron Number Benefits of Endurance Exercise Training for Females Born Small on a High Fat Diet.

Mary E Wlodek, Jessica Briffa, Sogand S Hosseini, Viktoria Richter, Dayana Mahizir, Kristina Anevska, Glenn D Wadley, Deanne H Hryciw, Karen M Moritz

Conference Proceedings  |  2018  |  REPRODUCTIVE SCIENCES

Sustained cardiac programming by short-term juvenile exercise training in male rats

Y Asif, ME Wlodek, MJ Black, AP Russell, PF Soeding, GD Wadley

Journal article  |  2018  |  The Journal of Physiology

Muscle redox signalling pathways in exercise. Role of antioxidants

Shaun A Mason, Dale Morrison, Glenn K McConell, Glenn D Wadley

Journal article  |  2016  |  Free Radical Biology and Medicine

Ascorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: Findings of a randomized controlled study

Shaun A Mason, Paul A Della Gatta, Rod J Snow, Aaron P Russell, Glenn D Wadley

Journal article  |  2016  |  Free Radical Biology and Medicine

Endurance training in early life results in long-term programming of heart mass in rats

Glenn D Wadley, Rhianna C Laker, Glenn K McConell, Mary E Wlodek

Journal article  |  2016  |  Physiological Reports

Maternal obesity in females born small: Pregnancy complications and offspring disease risk

Dayana Mahizir, Jessica F Briffa, Deanne H Hryciw, Glenn D Wadley, Karen M Moritz, Mary E Wlodek

Journal article  |  2016  |  Molecular Nutrition & Food Research

Uteroplacental insufficiency leads to hypertension, but not glucose intolerance or impaired skeletal muscle mitochondrial biogenesis, in 12-month-old rats

Melanie Tran, Margaret E Young, Andrew J Jefferies, Deanne H Hryciw, Michelle M Ward, Erica L Fletcher, Mary E Wlodek, Glenn D Wadley

Journal article  |  2015  |  Physiological Reports

High-dose vitamin C supplementation increases skeletal muscle vitamin C concentration and SVCT2 transporter expression but does not alter redox status in healthy males

Shaun A Mason, Raquel Baptista, Paul A Della Gatta, Adel Yousif, Aaron P Russell, Glenn D Wadley

Journal article  |  2014  |  Free Radical Biology and Medicine

Altering the redox state of skeletal muscle by glutathione depletion increases the exercise-activation of PGC-1α.

Natalie A Strobel, Aya Matsumoto, Jonathan M Peake, Susan A Marsh, Tina-Tinkara Peternelj, David Briskey, Robert G Fassett, Jeff S Coombes, Glenn D Wadley

Journal article  |  2014  |  Physiological Reports

We investigated the relationship between markers of mitochondrial biogenesis, cell signaling, and antioxidant enzymes by depleting..

Growing healthy muscles to optimise metabolic health into adult life

SA Bayol, CR Bruce, GD Wadley

Journal article  |  2014  |  Journal of Developmental Origins of Health and Disease

Growth restriction in the rat alters expression of cardiac JAK/STAT genes in a sex-specific manner

S van der Linde, T Romano, G Wadley, AJ Jeffries, ME Wlodek, DH Hryciw

Journal article  |  2014  |  Journal of Developmental Origins of Health and Disease

Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training

Aaron P Russell, Severine Lamon, Hanneke Boon, Shogo Wada, Isabelle Gueller, Erin L Brown, Alexander V Chibalin, Juleen R Zierath, Rod J Snow, Nigel Stepto, Glenn D Wadley, Takayuki Akimoto

Journal article  |  2013  |  The Journal of Physiology

A role for reactive oxygen species in the regulation of skeletal muscle hypertrophy

GD Wadley

Journal article  |  2013  |  Acta Physiologica

Xanthine oxidase inhibition attenuates skeletal muscle signaling following acute exercise but does not impair mitochondrial adaptations to endurance training

GD Wadley, MA Nicolas, DS Hiam, GK McConell

Journal article  |  2013  |  American Journal of Physiology - Endocrinology and Metabolism

Growth restriction in the rat alters expression of metabolic genes during postnatal cardiac development in a sex-specific manner

Glenn D Wadley, Glenn K McConell, Craig A Goodman, Andrew L Siebel, Kerryn T Westcott, Mary E Wlodek

Journal article  |  2013  |  Physiological Genomics

Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis

Aaron P Russell, Shogo Wada, Lodovica Vergani, M Benjamin Hock, Severine Lamon, Bertrand Leger, Takashi Ushida, Romain Cartoni, Glenn D Wadley, Peter Hespel, Anastasia Kralli, Gianni Soraru, Corrado Angelini, Takayuki Akimoto

Journal article  |  2013  |  Neurobiology of Disease

Short-Term Intensified Cycle Training Alters Acute and Chronic Responses of PGC1 alpha and Cytochrome C Oxidase IV to Exercise in Human Skeletal Muscle

Nigel K Stepto, Boubacar Benziane, Glenn D Wadley, Alexander V Chibalin, Benedict J Canny, Nir Eynon, Glenn K McConell

Journal article  |  2012  |  PLoS ONE

Effect of Pregnancy for Females Born Small on Later Life Metabolic Disease Risk

Melanie Tran, Linda A Gallo, Glenn D Wadley, Andrew J Jefferies, Karen M Moritz, Mary E Wlodek

Journal article  |  2012  |  PLoS One

Skeletal muscle nitric oxide signaling and exercise: a focus on glucose metabolism

Glenn K McConell, Stephen Rattigan, Robert S Lee-Young, Glenn D Wadley, Troy L Merry

Journal article  |  2012  |  American Journal of Physiology-Endocrinology and Metabolism

Exercise early in life in rats born small does not normalize reductions in skeletal muscle PGC-1 alpha in adulthood

Rhianna C Laker, Mary E Wlodek, Glenn D Wadley, Linda A Gallo, Peter J Meikle, Glenn K McConell

Journal article  |  2012  |  American Journal of Physiology - Endocrinology and Metabolism

Stage of perinatal development regulates skeletal muscle mitochondrial biogenesis and myogenic regulatory factor genes with little impact of growth restriction or cross-fostering

RC Laker, GD Wadley, GK McConell, ME Wlodek

Journal article  |  2012  |  Journal of Developmental Origins of Health and Disease

Short-term exercise training early in life restores deficits in pancreatic beta-cell mass associated with growth restriction in adult male rats

Rhianna C Laker, Linda A Gallo, Mary E Wlodek, Andrew L Siebel, Glenn D Wadley, Glenn K McConell

Journal article  |  2011  |  American Journal of Physiology - Endocrinology and Metabolism

Effect of L-Arginine Infusion on Glucose Disposal during Exercise in Humans

Kelly C Linden, Glenn D Wadley, Andrew P Garnham, Glenn K McConell

Journal article  |  2011  |  Medicine and Science in Sports and Exercise

Antioxidant Supplementation Reduces Skeletal Muscle Mitochondrial Biogenesis

Natalie A Strobel, Jonathan M Peake, Aya Matsumoto, Susan A Marsh, Jeff S Coombes, Glenn D Wadley

Journal article  |  2011  |  Medicine and Science in Sports and Exercise

Central infusion of leptin does not increase AMPK signaling in skeletal muscle of sheep

Rhianna C Laker, Belinda A Henry, Glenn D Wadley, Iain J Clarke, Benedict J Canny, Glenn K McConell

Journal article  |  2011  |  American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

Effect of l-arginine infusion on glucose disposal during exercise in humans.

KC Linden, GD Wadley, AP Garnham, GK McConell

Journal article  |  2011  |  Medicine and science in sports and exercise

Growth restriction before and after birth increases kinase signaling pathways in the adult rat heart

GD Wadley, ME Wlodek, G Ng, C Goodman, C Stathis, GK McConell

Journal article  |  2010  |  Journal of Developmental Origins of Health and Disease

High-dose antioxidant vitamin C supplementation does not prevent acute exercise-induced increases in markers of skeletal muscle mitochondrial biogenesis in rats

GD Wadley, GK McConell

Journal article  |  2010  |  Journal of Applied Physiology

N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans

Troy L Merry, Glenn D Wadley, Christos G Stathis, Andrew P Garnham, Stephen Rattigan, Mark Hargreaves, Glenn K McConell

Journal article  |  2010  |  Journal of Physiology

Central role of nitric oxide synthase in AICAR and caffeine-induced mitochondrial biogenesis in L6 myocytes

GK McConell, GPY Ng, M Phillips, Z Ruan, SL Macaulay, GD Wadley

Journal article  |  2010  |  Journal of Applied Physiology

POTENTIAL ROLE OF NITRIC OXIDE IN CONTRACTION-STIMULATED GLUCOSE UPTAKE AND MITOCHONDRIAL BIOGENESIS IN SKELETAL MUSCLE

Glenn K McConell, Glenn D Wadley

Journal article  |  2008  |  Clinical and Experimental Pharmacology and Physiology

Differential attenuation of AMPK activation during acute exercise following exercise training or AICAR treatment

GK McConell, A Manimmanakorn, RS Lee-Young, BE Kemp, KC Linden, GD Wadley

Journal article  |  2008  |  Journal of Applied Physiology

Uteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat

Glenn D Wadley, Andrew L Siebel, Greg J Cooney, Glenn K McConell, Mary E Wlodek, Julie A Owens

Journal article  |  2008  |  American Journal of Physiology - Endocrinology and Metabolism

Reply from G. D. Wadley, J. Choate and G. K. McConell

GD Wadley, J Choate, GK McConell

Journal article  |  2008  |  Journal of Physiology

Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats

Renee M Ross, Glenn D Wadley, Michael G Clark, Stephen Rattigan, Glenn K McConell

Journal article  |  2007  |  Diabetes

NOS isoform-specific regulation of basal but not exercise-induced mitochondrial biogenesis in mouse skeletal muscle

GD Wadley, J Choate, GK McConell

Journal article  |  2007  |  Journal of Physiology

Increased insulin-stimulated Akt pSer473and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training

Glenn D Wadley, Nicky Konstantopoulos, Lance Macaulay, Kirsten F Howlett, Andrew Garnham, Mark Hargreaves, David Cameron-Smith

Journal article  |  2007  |  Journal of Applied Physiology

Increased insulin-stimulated Akt pSer(473) and cytosolic SHP2 protein abundance in human skeletal muscle following acute exercise and short-term training

Glenn D Wadley, Nicky Konstantopoulos, Lance Macaulay, Kirsten F Howlett, Andrew Garnham, Mark Hargreaves, David Cameron-Smith

Journal article  |  2007  |  Journal of Applied Physiology

Effect of nitric oxide synthase inhibition on mitochondrial biogenesis in rat skeletal muscle

GD Wadley, GK McConell

Journal article  |  2007  |  Journal of Applied Physiology

Carbohydrate ingestion does not alter skeletal muscle AMPK signaling during exercise in humans

Robert S Lee-Young, Matthew J Palmer, Kelly C Linden, Kieran LePlastrier, Benedict J Canny, Mark Hargreaves, Glenn D Wadley, Bruce E Kemp, Glenn K McConell

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans

GD Wadley, RS Lee-Young, BJ Canny, C Wasuntarawat, ZP Chen, M Hargreaves, BE Kemp, GK McConell

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

L-Arginine infusion increases glucose clearance during prolonged exercise in humans

GK McConell, NN Huynh, RS Lee-Young, BJ Canny, GD Wadley

Journal article  |  2006  |  American Journal of Physiology - Endocrinology and Metabolism

The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats

GD Wadley, CR Bruce, N Konstantopoulos, SL Macaulay, KF Howlett, JA Hawley, D Cameron-Smith

Journal article  |  2004  |  Diabetologia

UCP3 protein expression is lower in type I, IIa and IIx muscle fiber types of endurance-trained compared to untrained subjects

AP Russell, G Wadley, MKC Hesselink, G Schaart, S Lo, B Leger, A Garnham, E Kornips, D Cameron-Smith, JP Giacobino, P Muzzin, R Snow, P Schrauwen

Journal article  |  2003  |  Pflügers Archiv - European Journal of Physiology

Slow component of VO2 kinetics: the effect of training status, fibre type, UCP3 mRNA and citrate synthase activity

A Russell, G Wadley, R Snow, JP Giacobino, P Muzzin, A Garnham, D Cameron-Smith

Journal article  |  2002  |  International Journal of Obesity

Differential effects of exercise on insulin-signaling gene expression in human skeletal muscle

GD Wadley, RJ Tunstall, A Sanigorski, GR Collier, M Hargreaves, D Cameron-Smith

Journal article  |  2001  |  Journal of Applied Physiology

The relationship between repeated sprint ability and the aerobic and anaerobic energy systems.

G Wadley, P Le Rossignol

Journal article  |  1998  |  Journal of Science and Medicine in Sport

A large number of team games require participants to repeatedly produce maximal or near maximal sprints of short duration with bri..