Mark Cook

Enlarged hippocampal fissure in psychosis of epilepsy.

James Allebone, Richard A Kanaan, Jerome J Maller, Terrence O'Brien, Saul Mullen, Mark Cook, Sophie Adams, Simon Vogrin, David Vaughan, Alan Connelly, Patrick Kwan, Samuel F Berkovic, Wendyl D'Souza, Graeme Jackson, Dennis Velakoulis, Sarah J Wilson

Journal article  |  2020  |  Epilepsy & Behavior

Psychosis of epilepsy (POE) can be a devastating condition, and its neurobiological basis remains unclear. In a previous study, we..

Domino-like transient dynamics at seizure onset in epilepsy

Jennifer Creaser, Congping Lin, Thomas Ridler, Jonathan T Brown, Wendyl D'Souza, Udaya Seneviratne, Mark Cook, John R Terry, Krasimira Tsaneva-Atanasova

Journal article  |  2020  |  PLOS Computational Biology

The International League Against Epilepsy (ILAE) groups seizures into "focal", "generalized" and "unknown" based on whether the se..

A new era in electroencephalographic monitoring? Subscalp devices for ultra-long-term recordings

Jonas Duun-Henriksen, Maxime Baud, Mark P Richardson, Mark Cook, George Kouvas, John M Heasman, Daniel Friedman, Jukka Peltola, Ivan C Zibrandtsen, Troels W Kjaer

Journal article  |  2020  |  Epilepsia

Mortality in patients with psychogenic nonepileptic seizures.

Russell Nightscales, Lara McCartney, Clarissa Auvrez, Gerard Tao, Sarah Barnard, Charles B Malpas, Piero Perucca, Anne McIntosh, Zhibin Chen, Shobi Sivathamboo, Sophia Ignatiadis, Simon Jones, Sophia Adams, Mark J Cook, Patrick Kwan, Dennis Velakoulis, Wendyl D'Souza, Samuel F Berkovic, Terence J O'Brien

Journal article  |  2020  |  Neurology

OBJECTIVE: To investigate the hypothesis that patients diagnosed with psychogenic nonepileptic seizures (PNES) on video-EEG monito..

Machine learning and wearable devices of the future

Sandor Beniczky, Philippa Karoly, Ewan Nurse, Philippe Ryvlin, Mark Cook

Journal article  |  2020  |  Epilepsia

Machine learning (ML) is increasingly recognized as a useful tool in healthcare applications, including epilepsy. One of the most ..

Seizure forecasting and cyclic control of seizures

Rachel E Stirling, Mark J Cook, David B Grayden, Philippa J Karoly

Journal article  |  2020  |  Epilepsia

Epilepsy is a unique neurologic condition characterized by recurrent seizures, where causes, underlying biomarkers, triggers, and ..

A taxonomy of seizure dynamotypes

Maria Luisa Saggio, Dakota Crisp, Jared M Scott, Philippa Karoly, Levin Kuhlmann, Mitsuyoshi Nakatani, Tomohiko Murai, Matthias Duempelmann, Andreas Schulze-Bonhage, Akio Ikeda, Mark Cook, Stephen Gliske, Jack Lin, Christophe Bernard, Viktor Jirsa, William C Stacey

Journal article  |  2020  |  eLife

Seizures are a disruption of normal brain activity present across a vast range of species and conditions. We introduce an organizi..

Signal quality and patient experience with wearable devices for epilepsy management

Mona Nasseri, Ewan Nurse, Martin Glasstetter, Sebastian Boettcher, Nicholas M Gregg, Aiswarya Laks Nandakumar, Boney Joseph, Tal Pal Attia, Pedro F Viana, Elisa Bruno, Andrea Biondi, Mark Cook, Gregory A Worrell, Andreas Schulze-Bonhage, Matthias Duempelmann, Dean R Freestone, Mark P Richardson, Benjamin H Brinkmann

Journal article  |  2020  |  Epilepsia

Noninvasive wearable devices have great potential to aid the management of epilepsy, but these devices must have robust signal qua..

Critical slowing down as a biomarker for seizure susceptibility.

Matias I Maturana, Christian Meisel, Katrina Dell, Philippa J Karoly, Wendyl D'Souza, David B Grayden, Anthony N Burkitt, Premysl Jiruska, Jan Kudlacek, Jaroslav Hlinka, Mark J Cook, Levin Kuhlmann, Dean R Freestone

Journal article  |  2020  |  Nature Communications

The human brain has the capacity to rapidly change state, and in epilepsy these state changes can be catastrophic, resulting in lo..

Anti-seizure therapy with a long-term, implanted intra-cerebroventricular delivery system for drug-resistant epilepsy: A first-in-man study.

Mark Cook, Michael Murphy, Kristian Bulluss, Wendyl D'Souza, Chris Plummer, Emma Priest, Catherine Williams, Ashwini Sharan, Robert Fisher, Sharon Pincus, Eric Distad, Tom Anchordoquy, Dan Abrams

Journal article  |  2020  |  EClinicalMedicine

Background: A clinical feasibility study was undertaken at a single center of long-term intra-cerebroventricular drug delivery of ..