Rinaldo Bellomo

Characteristics and Outcomes of Critically Ill Trauma Patients in Australia and New Zealand (2005-2017)

Anthony J Wilson, Fraser Magee, Michael Bailey, David V Pilcher, Craig French, Alistair Nichol, Andrew Udy, Carol L Hodgson, D James Cooper, Michael C Reade, Paul Young, Rinaldo Bellomo

Journal article  |  2020  |  Critical Care Medicine

OBJECTIVES: To compare the characteristics of adults admitted to the ICU in Australia and New Zealand after trauma with nonelectiv..

Systematic review and meta-analysis of the perioperative use of vasoactive drugs on postoperative outcomes after major abdominal surgery

Carolyn Deng, Rinaldo Bellomo, Paul Myles

Journal article  |  2020  |  British Journal of Anaesthesia

BACKGROUND: The perioperative use of vasoactive drugs is ubiquitous in clinical anaesthesia; yet, the drugs, doses, and haemodynam..

Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals

Daniel E Leisman, Michael O Harhay, David J Lederer, Michael Abramson, Alex A Adjei, Jan Bakker, Zuhair K Ballas, Esther Barreiro, Scott C Bell, Rinaldo Bellomo, Jonathan A Bernstein, Richard D Branson, Vito Brusasco, James D Chalmers, Sudhansu Chokroverty, Giuseppe Citerio, Nancy A Collop, Colin R Cooke, James D Crapo, Gavin Donaldson, et al.

Journal article  |  2020  |  Critical Care Medicine

Prediction models aim to use available data to predict a health state or outcome that has not yet been observed. Prediction is pri..

Assessing TEG6S reliability between devices and across multiple time points: A prospective thromboelastography validation study

Patryck Lloyd-Donald, Leonid Churilov, Brandon Cheong, Rinaldo Bellomo, Peter R McCall, Johan Martensson, Neil Glassford, Laurence Weinberg

Journal article  |  2020  |  Scientific Reports

The TEG6S is a novel haemostasis analyser utilising resonance technology. It offers potentially greater coagulation information an..

Prospective Longitudinal Evaluation of Coagulation with Novel Thromboelastography Technology in Patients After Subarachnoid Hemorrhage: A Pilot Study

Khaled El-Khawas, Patryck Lloyd-Donald, Graeme K Hart, Augusto Gonzalvo, Carole Smith, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2020  |  World Neurosurgery

BACKGROUND: There is limited knowledge of whether hypercoagulability is present after subarachnoid hemorrhage (SAH) or about its t..

Outcomes Six Months after Delivering 100% or 70% of Enteral Calorie Requirements during Critical Illness (TARGET) A Randomized Controlled Trial

Adam M Deane, Lorraine Little, Rinaldo Bellomo, Marianne J Chapman, Andrew R Davies, Suzie Ferrie, Michael Horowitz, Sally Hurford, Kylie Lange, Edward Litton, Diane Mackle, Stephanie O'Connor, Jane Parker, Sandra L Peake, Jeffrey J Presneill, Emma J Ridley, Vanessa Singh, Frank van Haren, Patricia Williams, Paul Young, et al.

Journal article  |  2020  |  American Journal of Respiratory and Critical Care Medicine

Rationale: The long-term effects of delivering approximately 100% of recommended calorie intake via the enteral route during criti..

Vitamin C measurement in critical illness: challenges, methodologies and quality improvements

Jake TB Collie, Ronda F Greaves, Oliver AH Jones, Glenn Eastwood, Rinaldo Bellomo

Journal article  |  2020  |  Clinical Chemistry and Laboratory Medicine (CCLM)

Background There is renewed interest in high-dose vitamin C interventions in clinical medicine due to its antioxidant properties, ..

The epidemiology of overfeeding in mechanically ventilated intensive care patients

Aiko Tanaka, Kate Hamilton, Glenn M Eastwood, Daryl Jones, Rinaldo Bellomo

Journal article  |  2020  |  Clinical Nutrition ESPEN

BACKGROUND AND AIMS: Nutrition research in the Intensive Care Unit (ICU) typically focusses on the epidemiology of underfeeding, p..

Timing of Onset, Burden, and Postdischarge Mortality of Persistent Critical Illness in Scotland, 2005-2014: A Retrospective, Population-Based, Observational Study.

Martin Shaw, Elizabeth M Viglianti, Joanne McPeake, Sean M Bagshaw, David Pilcher, Rinaldo Bellomo, Theodore J Iwashyna, Tara Quasim

Journal article  |  2020  |  Critical Care Explorations

We aimed to understand the prevalence, timing of onset, resource use, and long-term outcomes of patients who developed persistent ..

Decreased mean perfusion pressure as an independent predictor of acute kidney injury after cardiac surgery

Raymond Hu, Yasmean Kalam, Jeremy Broad, Tim Ho, Frank Parker, Matthew Lee, Rinaldo Bellomo

Journal article  |  2020  |  Heart and Vessels

Acute kidney injury after cardiac surgery (AKICS) is common. Previous studies examining the role that mean arterial pressure (MAP)..

Conservative Oxygen Therapy during Mechanical Ventilation in the ICU.

undefined ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, Diane Mackle, Rinaldo Bellomo, Michael Bailey, Richard Beasley, Adam Deane, Glenn Eastwood, Simon Finfer, Ross Freebairn, Victoria King, Natalie Linke, Edward Litton, Colin McArthur, Shay McGuinness, Rakshit Panwar, Paul Young, undefined ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group

Journal article  |  2020  |  New England Journal of Medicine

BACKGROUND: Patients who are undergoing mechanical ventilation in the intensive care unit (ICU) often receive a high fraction of i..

The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: Data from the multinational SMARRT Study.

Jason A Roberts, Gavin Joynt, Anna Lee, Gordon Choi, Rinaldo Bellomo, Salmaan Kanji, M Yugan Mudaliar, Sandra L Peake, Dianne Stephens, Fabio Silvio Taccone, Marta Ulldemolins, Miia Maaria Valkonen, Julius Agbeve, João P Baptista, Vasileios Bekos, Clement Boidin, Alexander Brinkmann, Luke Buizen, Pedro Castro, C Louise Cole, et al.

Journal article  |  2020  |  Clinical Infectious Diseases

BACKGROUND: The optimal dosing of antibiotics in critically ill patients receiving renal replacement therapy (RRT) remains unclear..

Characteristics and Outcomes of Critically Ill Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Australia and New Zealand.

Freya Berenyi, Daniel P Steinfort, Yasmine Ali Abdelhamid, Michael J Bailey, David V Pilcher, Rinaldo Bellomo, Mark E Finnis, Paul J Young, Adam M Deane

Journal article  |  2020  |  Annals of the American Thoracic Society

RATIONALE: The characteristics and outcomes of patients presenting with an acute exacerbation of chronic obstructive pulmonary dis..

Point-of-care creatinine measurements to predict acute kidney injury

Suvi T Vaara, Neil Glassford, Glenn M Eastwood, Emmanuel Canet, Johan Martensson, Rinaldo Bellomo

Journal article  |  2020  |  Acta Anaesthesiologica Scandinavica

BACKGROUND: Plasma creatinine (Cr) is a marker of kidney function and typically measured once daily. We hypothesized that Cr measu..

Stability of bicarbonate in normal saline: a technical report.

Thummaporn Naorungroj, Ary Serpa Neto, Tomoko Fujii, Briony Jude, Andrew Udy, Rinaldo Bellomo

Journal article  |  2020  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

BACKGROUND: The benefit of intravenous sodium bicarbonate administration in patients with severe metabolic acidosis remains contro..

Sodium bicarbonate in 5% dextrose: can clinicians tell the difference?

Briony Jude, Thummaporn Naorungroj, Ary Serpa Neto, Tomoko Fujii, Andrew Udy, Rinaldo Bellomo

Journal article  |  2020  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

BACKGROUND: Due to the lack of double-blind randomised controlled trials, the true effect of intravenous sodium bicarbonate therap..

Sustained High-dose Thiamine Supplementation in High-risk Cardiac Patients Undergoing Cardiopulmonary Bypass: A Pilot Feasibility Study (The APPLY trial)

Vladimir V Lomivorotov, Gleb Moroz, Samandar Ismoilov, Vladimir Shmyrev, Sergey Efremov, Marat Abubakirov, Vasily Batalov, Giovanni Landoni, Rosalba Lembo, Alexander Bogachev-Prokophiev, Andrey Sapegin, Rinaldo Bellomo

Journal article  |  2020  |  Journal of Cardiothoracic and Vascular Anesthesia

OBJECTIVE: To test the feasibility and investigate possible cardiovascular effects of a sustained high-dose intravenous thiamine p..

Haemodynamic effect of a 20% albumin fluid bolus in post-cardiac surgery patients.

Salvatore L Cutuli, Laurent Bitker, Eduardo A Osawa, Zachary O'Brien, Emmanuel Canet, Fumitaka Yanase, Paolo Ancona, Anthony Wilson, Luca Lucchetta, Mark Kubicki, Maria Cronhjort, Luca Cioccari, Lea Peck, Helen Young, Glenn M Eastwood, Johan Mårtensson, Neil J Glassford, Rinaldo Bellomo

Journal article  |  2020  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVE: To study the cardiovascular effect over 30 minutes following the end of fluid bolus therapy (FBT) with 20% albumin in p..

Relative Hypoglycemia in Diabetic Patients With Critical Illness

Timothy N Kwan, Lara Zwakman-Hessels, Nada Marhoon, Ray Robbins, Johan Martensson, Elif Ekinci, Rinaldo Bellomo

Journal article  |  2020  |  Critical Care Medicine

OBJECTIVES: Relative hypoglycemia is a decrease in glucose greater than or equal to 30% below prehospital admission levels (estima..

Dilution or Decrease in Prevalence and Mortality of Patients With Variceal Bleeding Admitted to the ICU Reply

Ammar Majeed, Avik Majumdar, Michael Bailey, William Kemp, Rinaldo Bellomo, David Pilcher, Stuart K Roberts

Journal article  |  2020  |  Critical Care Medicine

The implications of the PEPTIC trial for clinical practice.

Paul J Young, Sean M Bagshaw, Rinaldo Bellomo, Alistair D Nichol, Stephen E Wright

Journal article  |  2020  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Prevalence, characteristics, drainage and outcome of radiologically diagnosed pleural effusions in critically ill patients.

Davina Bates, Natalie Yang, Michael Bailey, Rinaldo Bellomo

Journal article  |  2020  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVE: Pleural effusions in the intensive care unit (ICU) are clinically important. However, there is limited information rega..

Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation The PEPTIC Randomized Clinical Trial

Paul J Young, Sean M Bagshaw, Andrew B Forbes, Alistair D Nichol, Stephen E Wright, Michael Bailey, Rinaldo Bellomo, Richard Beasley, Kathy Brickell, Glenn M Eastwood, David J Gattas, Frank Van Haren, Edward Litton, Diane M Mackle, Colin J McArthur, Shay P McGuinness, Paul R Mouncey, Leanlove Navarra, Dawn Opgenorth, David Pilcher, et al.

Journal article  |  2020  |  JAMA

Importance: Proton pump inhibitors (PPIs) or histamine-2 receptor blockers (H2RBs) are often prescribed for patients as stress ulc..

30-Day Outcomes Post Veno-Arterial Extra Corporeal Membrane Oxygenation (VA-ECMO) After Cardiac Surgery and Predictors of Survival.

Raymond TC Hu, Jeremy D Broad, Eduardo A Osawa, Paolo Ancona, Yoko Iguchi, Lachlan F Miles, Rinaldo Bellomo

Journal article  |  2020  |  Heart, Lung and Circulation

BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is sometimes needed for post-cardiotomy cardiogenic shock ..

The Australasian Resuscitation In Sepsis Evaluation: Fluids or vasopressors in emergency department sepsis (ARISE FLUIDS), a multi-centre observational study describing current practice in Australia and New Zealand

Gerben Keijzers, Stephen PJ Macdonald, Andrew A Udy, Glenn Arendts, Michael Bailey, Rinaldo Bellomo, Gabriel E Blecher, Jonathon Burcham, Andrew R Coggins, Anthony Delaney, Daniel M Fatovich, John F Fraser, Amanda Harley, Peter Jones, Frances B Kinnear, Katya May, Sandra Peake, David McD Taylor, Patricia Williams, Nguyen Khanh, et al.

Journal article  |  2020  |  Emergency Medicine Australasia

OBJECTIVES: To describe haemodynamic resuscitation practices in ED patients with suspected sepsis and hypotension. METHODS: This w..

Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock

Rinaldo Bellomo, Richard G Wunderink, Harold Szerlip, Shane W English, Laurence W Busse, Adam M Deane, Ashish K Khanna, Michael T McCurdy, Marlies Ostermann, Paul J Young, Damian R Handisides, Lakhmir S Chawla, George F Tidmarsh, Timothy E Albertson

Journal article  |  2020  |  Critical Care

BACKGROUND: In patients with vasodilatory shock, plasma concentrations of angiotensin I (ANG I) and II (ANG II) and their ratio ma..

Effect of nephrology follow-up on long-term outcomes in patients with acute kidney injury: A systematic review and meta-analysis.

Nan Ye, Ying Xu, Rinaldo Bellomo, Martin Gallagher, Amanda Y Wang

Journal article  |  2020  |  Nephrology

AIM: Acute kidney injury (AKI) is associated with poor short-term and long-term clinical outcomes. The role of nephrology follow-u..

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock The VITAMINS Randomized Clinical Trial

Tomoko Fujii, Nora Luethi, Paul J Young, Daniel R Frei, Glenn M Eastwood, Craig J French, Adam M Deane, Yahya Shehabi, Ludhmila A Hajjar, Gisele Oliveira, Andrew A Udy, Neil Orford, Samantha J Edney, Anna L Hunt, Harriet L Judd, Laurent Bitker, Luca Cioccari, Thummaporn Naorungroj, Fumitaka Yanase, Samantha Bates, et al.

Journal article  |  2020  |  JAMA

Importance: It is unclear whether vitamin C, hydrocortisone, and thiamine are more effective than hydrocortisone alone in expediti..

Correction and Control of Hyperammonemia in Acute Liver Failure: The Impact of Continuous Renal Replacement Timing, Intensity, and Duration

Stephen Warrillow, Caleb Fisher, Rinaldo Bellomo

Journal article  |  2020  |  Critical Care Medicine

OBJECTIVES: Hyperammonemia is a key contributing factor for cerebral edema in acute liver failure. Continuous renal replacement th..

Randomised controlled trial to investigate the relationship between mild hypercapnia and cerebral oxygen saturation in patients undergoing major surgery

Clarence Wong, Leonid Churilov, Dean Cowie, Chong Oon Tan, Raymond Hu, David Tremewen, Brett Pearce, Param Pillai, Dharshi Karalapillai, Rinaldo Bellomo, Laurence Weinberg

Journal article  |  2020  |  BMJ Open

OBJECTIVES: The effects of hypercapnia on regional cerebral oxygen saturation (rSO2) during surgery are unclear. We conducted a ra..

Responsiveness of Noninvasive Continuous Cardiac Output Monitoring During the Valsalva Maneuver

LJ Delaney, R Bellomo, F van Haren

Journal article  |  2020  |  Clinical Nursing Research

To describe the baseline hemodynamic variables and response time of hemodynamic changes associated with the Valsalva maneuver usin..

Gender differences in mortality and quality of life after septic shock: A post-hoc analysis of the ARISE study

Nora Luethi, Michael Bailey, Alisa Higgins, Belinda Howe, Sandra Peake, Anthony Delaney, Rinaldo Bellomo, V Bennett, J Board, P McCracken, S McGloughlin, V Nanjayya, A Teo, E Hill, P Jones E O'Brien, F Sawtell, K Schimanski, D Wilson, R Bellomo, S Bolch, et al.

Journal article  |  2020  |  Journal of Critical Care

PURPOSE: To assess the impact of gender and pre-menopausal state on short- and long-term outcomes in patients with septic shock. M..

Net Ultrafiltration Prescription and Practice Among Critically Ill Patients Receiving Renal Replacement Therapy: A Multinational Survey of Critical Care Practitioners

Raghavan Murugan, Marlies Ostermann, Zhiyong Peng, Koichi Kitamura, Shigeki Fujitani, Stefano Romagnoli, Luca Di Lullo, Nattachai Srisawat, Subhash Todi, Nagarajan Ramakrishnan, Eric Hoste, Chethan M Puttarajappa, Sean M Bagshaw, Steven Weisbord, Paul M Palevsky, John A Kellum, Rinaldo Bellomo, Claudio Ronco

Journal article  |  2020  |  Critical Care Medicine

OBJECTIVES: To assess the attitudes of practitioners with respect to net ultrafiltration prescription and practice among criticall..

Pilot, Double-Blind, Randomized, Controlled Trial of High-Dose Intravenous Vitamin C for Vasoplegia After Cardiac Surgery

Fumitaka Yanase, Laurent Bitker, Lara Hessels, Eduardo Osawa, Thummaporn Naorungroj, Salvatore L Cutuli, Paul J Young, Jay Ritzema, Georgia Hill, Charlotte Latimer-Bell, Anna Hunt, Glenn M Eastwood, Andrew Hilton, Rinaldo Bellomo

Journal article  |  2020  |  Journal of Cardiothoracic and Vascular Anesthesia

OBJECTIVE: To conduct a pilot feasibility and physiologic efficacy study of high-dose vitamin C in patients with vasoplegia after ..

Renal hemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep under total intravenous anesthesia

Roger G Evans, Naoya Iguchi, Andrew D Cochrane, Bruno Marino, Sally G Hood, Rinaldo Bellomo, Peter R McCall, Clive N May, Yugeesh R Lankadeva

Journal article  |  2020  |  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Renal medullary hypoxia may contribute to the pathophysiology of acute kidney injury, including that associated with cardiac surge..

Hourly Fluid Balance in Patients Receiving Continuous Renal Replacement Therapy

Thummaporn Naorungroj, Ary Serpa Neto, Lara Zwakman-Hessels, Fumitaka Yanase, Glenn Eastwood, Rinaldo Bellomo

Journal article  |  2020  |  Blood Purification

INTRODUCTION: Little is known about early (first 48 h) hourly and cumulative fluid balance (FB) during continuous renal replacemen..

Correction and Control of Hyperammonemia in Acute Liver Failure: The Impact of Continuous Renal Replacement Timing, Intensity, and Duration.

Stephen Warrillow, Caleb Fisher, Rinaldo Bellomo

Journal article  |  2020  |  Critical Care Medicine

OBJECTIVES: Hyperammonemia is a key contributing factor for cerebral edema in acute liver failure. Continuous renal replacement th..

Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX)

Paul Young, Diane Mackle, Rinaldo Bellomo, Michael Bailey, Richard Beasley, Adam Deane, Glenn Eastwood, Simon Finfer, Ross Freebairn, Victoria King, Natalie Linke, Edward Litton, Colin McArthur, Shay McGuinness, Rakshit Panwar

Journal article  |  2020  |  Intensive Care Medicine

PURPOSE: Sepsis is a common reason for intensive care unit (ICU) admission and mortality in ICU patients. Despite increasing inter..

Circuit Survival during Continuous Venovenous Hemodialysis versus Continuous Venovenous Hemofiltration.

Alfonso Maria Califano, Laurent Bitker, Ian Baldwin, Nigel Fealy, Rinaldo Bellomo

Journal article  |  2020  |  Blood Purification

BACKGROUND: Continuous renal replacement therapy (CRRT) technique may affect circuit lifespan. A shorter circuit life may reduce C..

Characteristics and outcomes of rapid response team activations for hypotension in orthopaedic patients

Joao GR Ramos, Richard Zhang, Brendan Maher, Andrew Hardidge, Laurence Weinberg, Ray Robbins, Phillip J Peyton, Rinaldo Bellomo, Daryl Jones

Journal article  |  2020  |  Internal Medicine Journal

BACKGROUND: Hypotension following orthopaedic surgery has been associated with increased morbidity and mortality. Rapid response t..

Diabetes and higher HbA1c levels are independently associated with adverse renal outcomes in inpatients following multiple hospital admissions

N Torkamani, L Churilov, R Robbins, G Jerums, V Beik, N Radcliffe, S Patterson, R Bellomo, J Burns, GK Hart, Q Lam, DA Power, RJ MacIsaac, DF Johnson, J Zajac, E Ekinci

Journal article  |  2020  |  Journal of Diabetes and its Complications

OBJECTIVE: To assess the association between glycaemic status prior to the first hospital presentation with developing adverse ren..

Serum sodium and intracranial pressure changes after desmopressin therapy in severe traumatic brain injury patients: a multi-centre cohort study (vol 9, 99, 2019)

A Harrois, JR Anstey, FS Taccone, AA Udy, G Citerio, J Duranteau, C Ichai, R Badenes, JR Prowle, A Ercole, M Oddo, A Schneider, M van der Jagt, S Wolf, R Helbok, DW Nelson, MB Skrifvars, DJ Cooper, R Bellomo, K Long, et al.

Journal article  |  2019  |  Annals of Intensive Care

Following publication of the original article [1], we were notified that the collaborators' names part of the "The TBI Collaborati..

The Risk of Hyperoxemia in ICU Patients Much Ado About O-2

Paul J Young, Rinaldo Bellomo

Journal article  |  2019  |  American Journal of Respiratory and Critical Care Medicine

Pharmacokinetic data support 6-hourly dosing of intravenous vitamin C to critically ill patients with septic shock

Elizabeth P Hudson, Jake TB Collie, Tomoko Fujii, Nora Luethi, Andrew A Udy, Sarah Doherty, Glenn Eastwood, Fumitaka Yanase, Thummaporn Naorungroj, Laurent Bitker, Yasmine Ali Abdelhamid, Ronda F Greaves, Adam M Deane, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVES: To study vitamin C pharmacokinetics in septic shock. DESIGN: Prospective pharmacokinetic study. SETTING: Two intensive..

O-2, do we know what to do?

Paul J Young, Sean M Bagshaw, Michael Bailey, Rinaldo Bellomo, Diane Mackie, David Pilcher, Giovanni Landoni, Alistair Nichol, Daniel Martin

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

The incidence, predictors and outcomes of QTc prolongation in critically ill patients

Hollie Russell, Leonid Churilov, Lisa Toh, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Critical Care

PURPOSE: To study the incidence, predictors and outcomes of QTc prolongation (≥500 ms) during ICU admission. METHODS: Prospective ..

Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock

Eduardo Atsushi Osawa, Salvatore Lucio Cutuli, Laurent Bitker, Emmanuel Canet, Luca Cioccari, Naoya Iguchi, Yugeesh R Lankadeva, Glenn M Eastwood, Roger G Evans, Clive N May, Rinaldo Bellomo

Journal article  |  2019  |  Blood Purification

BACKGROUND: Renal medullary hypoxia precedes the development of acute kidney injury in experimental sepsis and can now be assessed..

Hydrocortisone Compared with Placebo in Patients with Septic Shock Satisfying the Sepsis-3 Diagnostic Criteria and APROCCHSS Study Inclusion Criteria A Post Hoc Analysis of the ADRENAL Trial

Balasubramanian Venkatesh, Simon Finfer, Jeremy Cohen, Dorrilyn Rajbhandari, Yaseen Arabi, Rinaldo Bellomo, Laurent Billot, Parisa Glass, Christopher Joyce, Qiang Li, Colin McArthur, Anders Perner, Andrew Rhodes, Kelly Thompson, Steve Webb, John Myburgh

Journal article  |  2019  |  Anesthesiology

BACKGROUND: Two recent randomized controlled trials (Adjunctive Glucocorticoid Therapy in Patients with Septic Shock [ADRENAL] and..

Low tidal volume ventilation during anaesthesia for major surgery: protocol and statistical analysis plan

Dharshi Karalapillai, Laurence Weinberg, Phil Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong Tan, David Story, Mark ODonnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Anthony Wilson, Ary Serpa Neto, Glenn Eastwood, Rinaldo Bellomo, Daryl A Jones

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

BACKGROUND: Mechanical ventilation is mandatory in patients undergoing general anaesthesia for major surgery. Tidal volumes higher..

The Plasma-Lyte 148 versus Saline (PLUS) study protocol amendment

Naomi E Hammond, Rinaldo Bellomo, Martin Gallagher, David Gattas, Parisa Glass, Diane Mackie, Sharon Micallef, John Myburgh, Manoj Saxena, Colman Taylor, Paul Young, Simon Finfer

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

A pilot randomised controlled trial evaluating the pharmacodynamic effects of furosemide versus acetazolamide in critically ill patients

Alastair JW Brown, Salvatore L Cutuli, Glenn M Eastwood, Laurent Bitker, Philip Marsh, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVE: To compare the physiological and biochemical effects of a single intravenous dose of furosemide or acetazolamide in cri..

Patient characteristics, ICU-specific supports, complications, and outcomes of persistent critical illness

Toby Jeffcote, Monica Foong, Grace Gold, Neil Glassford, Raymond Robbins, Theodore J Iwashyna, Jai Darvall, Sean M Bagshaw, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Critical Care

OBJECTIVES: The primary objective was to identify the proportion of patients on mechanical ventilation (MV) beyond day 10, the rec..

Using language descriptors to recognise delirium: a survey of clinicians and medical coders to identify delirium-suggestive words

Natasha E Holmes, Sobia Amjad, Marcus Young, David J Berlowitz, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVE: To develop a library of delirium-suggestive words. DESIGN: Cross-sectional survey. SETTING: Single tertiary referral ho..

Differential clinical characteristics, management and outcome of delirium among ward compared with intensive care unit patients

Emmanuel Canet, Sobia Amjad, Raymond Robbins, Jane Lewis, Michelle Matalanis, Daryl Jones, Rinaldo Bellomo

Journal article  |  2019  |  Internal Medicine Journal

BACKGROUND: Delirium is common in hospitalised patients but its epidemiology remains poorly characterised. AIMS: To test the hypot..

Acute kidney injury

Claudio Ronco, Rinaldo Bellomo, John A Kellum

Book  |  2019  |  The Lancet

Acute kidney injury

C Ronco, R Bellomo, JA Kellum

Journal article  |  2019  |  The Lancet

Coagulation abnormalities, bleeding, thrombosis, and management of patients with acute liver failure in Australia and New Zealand

Stephen Warrillow, Caleb Fisher, Heath Tibballs, Michael Bailey, Colin McArthur, Pia Lawson-Smith, Bheemasenachar Prasad, Matthew Anstey, Bala Venkatesh, Gemma Dashwood, James Walsham, Andrew Holt, Ubbo Wiersema, David Gattas, Matthew Zoeller, Mercedes Garcia Alvarez, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Gastroenterology and Hepatology

BACKGROUND AND AIM: To study the management of coagulation and hematological derangements among severe acute liver failure (ALF) p..

HAS FLAIR Investigators Reply to Fluid Resuscitation After Cardiac Surgery: The Quest for the Ideal Fluid

Geoffrey Wigmore, James Anstey, Adam Deane, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Cardiothoracic and Vascular Anesthesia

20% Human Albumin Solution Fluid Bolus Administration Therapy in Patients After Cardiac Surgery (the HAS FLAIR Study)

Geoffrey J Wigmore, James R Anstey, Ashley St John, Joel Greaney, Marc Morales-Codina, Jeffrey J Presneill, Adam M Deane, Christopher M MacIsaac, Michael Bailey, James Tatoulis, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Cardiothoracic and Vascular Anesthesia

OBJECTIVE: To compare the effects of fluid bolus therapy using 20% albumin versus crystalloid on fluid balance, hemodynamic parame..

Circuit Hemodynamics and Circuit Failure During Continuous Renal Replacement Therapy

Benjamin Sansom, Shyamala Sriram, Jeffrey Presneill, Rinaldo Bellomo

Journal article  |  2019  |  Critical Care Medicine

Renal Medullary Hypoxia: A New Therapeutic Target for Septic Acute Kidney Injury?

Yugeesh R Lankadeva, Nobuki Okazaki, Roger G Evans, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  Seminars in Nephrology

Initial Experience of the Use of 3-Factor Prothrombin Complex Concentrate and Thromboembolic Complications After Cardiac Surgery

India Zweng, Sean Galvin, Ray Robbins, Rinaldo Bellomo, Graeme K Hart, Siven Seevanayagam, George Matalanis

Journal article  |  2019  |  Heart, Lung and Circulation

BACKGROUND: 3-factor prothrombin complex concentrate (3F-PCC) may provide a valuable treatment option for coagulopathy in cardiac ..

A Pilot Randomized Controlled Study of Mild Hypercapnia During Cardiac Surgery With Cardiopulmonary Bypass

Matthew J Chan, Luca Lucchetta, Salvatore Cutuli, Christopher Eyeington, Neil I Glassford, Johan Martensson, Peter Angelopoulos, George Matalanis, Lawrence Weinberg, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Cardiothoracic and Vascular Anesthesia

OBJECTIVES: To test whether targeted therapeutic mild hypercapnia (TTMH) would attenuate cerebral oxygen desaturation detected usi..

Vitamin C therapy for patients with sepsis or septic shock: a protocol for a systematic review and a network meta-analysis

Tomoko Fujii, Alessandro Belletti, Anitra Carr, Toshi A Furukawa, Nora Luethi, Alessandro Putzu, Chiara Sartini, Georgia Salanti, Yasushi Tsujimoto, Andrew A Udy, Paul J Young, Rinaldo Bellomo

Journal article  |  2019  |  BMJ Open

INTRODUCTION: Vasoplegia is common and associated with a poor prognosis in patients with sepsis and septic shock. Vitamin C therap..

Dexmedetomidine reduces norepinephrine requirements and preserves renal oxygenation and function in ovine septic acute kidney injury

Yugeesh R Lankadeva, Shuai Ma, Naoya Iguchi, Roger G Evans, Sally G Hood, David GS Farmer, Simon R Bailey, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  Kidney International

Norepinephrine exacerbates renal medullary hypoxia in experimental septic acute kidney injury. Here we examined whether dexmedetom..

Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials (vol 22, 6, 2018)

Luca Cabrini, Giovanni Landoni, Martina Baiardo Redaelli, Omar Saleh, Carmine D Votta, Evgeny Fominskiy, Alessandro Putzu, Cezar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi, Alberto Zangrillo

Journal article  |  2019  |  Critical Care

In the publication of this article [1], there was an error in a contributors Family Name. This has now been updated in the origina..

Borderline anaemia and postoperative outcome in women undergoing major abdominal surgery: a retrospective cohort study

LF Miles, T Larsen, MJ Bailey, KL Burbury, DA Story, R Bellomo

Journal article  |  2019  |  Anaesthesia

Pre-operative anaemia is typically diagnosed with a haemoglobin concentration < 120 g.l-1 for women and < 130 g.l-1 for men on the..

Initiation of vasopressor infusions via peripheral versus central access in patients with early septic shock: A retrospective cohort study

Anthony Delaney, Mark Finnis, Rinaldo Bellomo, Andrew Udy, Daryl Jones, Gerben Keijzers, Stephen Macdonald, Sandra Peake

Journal article  |  2019  |  Emergency Medicine Australasia

Development and Validation of a Score to Identify Cardiac Surgery Patients at High Risk of Prolonged Mechanical Ventilation

Lara Hessels, Tim G Coulson, Siven Seevanayagam, Paul Young, David Pilcher, Nada Marhoon, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Cardiothoracic and Vascular Anesthesia

OBJECTIVE: To develop and validate a score for the early identification of cardiac surgery patients at high risk of prolonged mech..

Randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial

Paul J Young, Michael J Bailey, Frances Bass, Richard W Beasley, Ross C Freebairn, Naomi E Hammond, Frank MP van Haren, Meg L Harward, Seton J Henderson, Diane M Mackle, Colin J McArthur, Shay P McGuinness, John A Myburgh, Manoj K Saxena, Anne M Turner, Steve AR Webb, Rinaldo Bellomo

Journal article  |  2019  |  Intensive Care Medicine

Non-invasive continuous haemodynamic monitoring and response to intervention in haemodynamically unstable patients during rapid response team review

Christopher T Eyeington, Patryck Lloyd-Donald, Matthew J Chan, Glenn M Eastwood, Helen Young, Leah Peck, Nada Marhoon, Daryl A Jones, Rinaldo Bellomo

Journal article  |  2019  |  Resuscitation

Incidence, Patient Characteristics, Mode of Drug Delivery, and Outcomes of Septic Shock Patients Treated With Vasopressors in the Arise Trial

Andrew A Udy, Mark Finnis, Daryl Jones, Anthony Delaney, Stephen Macdonald, Rinaldo Bellomo, Sandra Peake, V Bennett, J Board, P McCracken, S McGloughlin, V Nanjayya, A Teo, E Hill, P Jones, E O'Brien, F Sawtell, K Schimanski, D Wilson, R Bellomo, et al.

Journal article  |  2019  |  SHOCK

INTRODUCTION: To describe the utilization of vasopressors (VP) in patients enrolled in the Australasian Resuscitation In Sepsis Ev..

Frailty in very old critically ill patients in Australia and New Zealand: a population-based cohort study

Jai N Darvall, Rinaldo Bellomo, Eldho Paul, Ashwin Subramaniam, John D Santamaria, Sean M Bagshaw, Sumeet Rai, Ruth E Hubbard, David Pilcher

Journal article  |  2019  |  Medical Journal of Australia

DECLINING MORTALITY OF CIRRHOTIC PATIENTS REQUIRING ADMISSION TO INTENSIVE CARE UNITS FOR SERIOUS INFECTIONS: A BI-NATIONAL COHORT STUDY

Ammar Majeed, Michael Bailey, Avik Majumdar, William W Kemp, Rinaldo Bellomo, David Pilcher, Stuart K Roberts

Conference Proceedings  |  2019  |  HEPATOLOGY

A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality

Chiara Sartini, Vladimir Lomivorotov, Antonio Pisano, Hynek Riha, Martina Baiardo Redaelli, Juan Carlos Lopez-Delgado, Marina Pieri, Ludhmila Hajjar, Evgeny Fominskiy, Valery Likhvantsev, Luca Cabrini, Nikola Bradic, Daniele Avancini, Chew Yin Wang, Rosalba Lembo, Maxim Novikov, Gianluca Paternoster, Gordana Gazivoda, Gabriele Alvaro, Agostino Roasio, et al.

Journal article  |  2019  |  Journal of Cardiothoracic and Vascular Anesthesia

OBJECTIVE: Reducing mortality is a key target in critical care and perioperative medicine. The authors aimed to identify all nonsu..

Declining Mortality of Cirrhotic Variceal Bleeding Requiring Admission to Intensive Care: A Binational Cohort Study*

Ammar Majeed, Avik Majumdar, Michael Bailey, William Kemp, Rinaldo Bellomo, David Pilcher, Stuart K Roberts

Journal article  |  2019  |  Critical Care Medicine

OBJECTIVES: We aimed to describe changes over time in admissions and outcomes, including length of stay, discharge destinations, a..

Early Osmotherapy in Severe Traumatic Brain Injury: An International Multicenter Study

James R Anstey, Fabio S Taccone, Andrew A Udy, Giuseppe Citerio, Jacques Duranteau, Carole Ichai, Rafael Badenes, John R Prowle, Ari Ercole, Mauro Oddo, Antoine G Schneider, Mathieu van der Jagt, Stefan Wolf, Raimund Helbok, David W Nelson, Marius B Skrifvars, Anatole Harrois, Jeffrey Presneill, D Jamie Cooper, Michael Bailey, et al.

Journal article  |  2019  |  Journal of Neurotrauma

The optimal osmotic agent to treat intracranial hypertension in patients with severe traumatic brain injury (TBI) remains uncertai..

Serum sodium and intracranial pressure changes after desmopressin therapy in severe traumatic brain injury patients: a multi-centre cohort study

A Harrois, JR Anstey, FS Taccone, AA Udy, G Citerio, J Duranteau, C Ichai, R Badenes, JR Prowle, A Ercole, M Oddo, A Schneider, M van Der Jagt, S Wolf, R Helbok, DW Nelson, MB Skrifvars, DJ Cooper, R Bellomo, K Long, et al.

Journal article  |  2019  |  Annals of Intensive Care

Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units

Stephen Warrillow, Heath Tibballs, Michael Bailey, Colin McArthur, Pia Lawson-Smith, Bheemasenachar Prasad, Matthew Anstey, Balasubramanian Venkatesh, Gemma Dashwood, James Walsham, Andrew Holt, Ubbo Wiersema, David Gattas, Matthew Zoeller, Mercedes Garcia Alvarez, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Cost-Effectiveness of Erythropoietin in Traumatic Brain Injury: A Multinational Trial-Based Economic Analysis

Rachel J Knott, Anthony Harris, Alisa Higgins, Alistair Nichol, Craig French, Lorraine Little, Samir Haddad, Jeffrey Presneill, Yaseen Arabi, Michael Bailey, D James Cooper, Jacques Duranteau, Olivier Huet, Anne Mak, Colin McArthur, Ville Pettila, Markus B Skrifvars, Shirley Vallance, Dinesh Varma, Judy Wills, et al.

Journal article  |  2019  |  Journal of Neurotrauma

The EPO-TBI multi-national randomized controlled trial found that erythropoietin (EPO), when compared to placebo, did not affect 6..

Declining mortality of patients with cirrhosis requiring admission to intensive care units for serious infections: A binational cohort study

A Majeed, M Bailey, A Majumdar, W Kemp, R Bellomo, D Pilcher, S Roberts

Conference Proceedings  |  2019  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

In this issue of CCR.

Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Opinions and practices of blood glucose control in critically ill patients with pre-existing type 2 diabetes in Australian and New Zealand intensive care units

Alexis P Poole, James Anstey, Rinaldo Bellomo, Vishwanath Biradar, Adam M Deane, Simon R Finfer, Mark E Finnis, Craig J French, Palash Kar, Peter S Kruger, Matthew J Maiden, Johan Martensson, Colin J McArthur, Shay P McGuinness, Paul J Secombe, Antony E Tobin, Andrew A Udy, Glenn M Eastwood

Journal article  |  2019  |  Australian Critical Care

BACKGROUND: Approximately 9000 patients with type-2 diabetes mellitus (T2DM) are admitted to an intensive care unit (ICU) in Austr..

Renal replacement therapy in the ICU: when should we STARRT?

Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

HMG-CoA reductase inhibitors (statins) and acute kidney injury: A secondary analysis of renal study outcomes

Amanda Y Wang, Konlawij Trongtrakul, Rinaldo Bellomo, Qiang Li, Alan Cass, Martin Gallagher

Journal article  |  2019  |  Nephrology

BACKGROUND: Mortality in intensive care unit (ICU) patients with acute kidney injury (AKI) remains high. Previous studies have exp..

Micronutrient deficiency in critical illness: an invisible foe?

Michael P Casaer, Rinaldo Bellomo

Journal article  |  2019  |  Intensive Care Medicine

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators

Guy Haller, Sohail Bampoe, Tim Cook, Lee A Fleisher, Michael PW Grocott, Mark Neuman, David Story, Paul S Myles, Paul Myles, Michael Grocott, Bruce Biccard, Jane Blazeby, Oliver Boney, Matthew Chan, Elisabeth Diouf, Lee Fleisher, Cor Kalkman, Andrea Kurz, Ramani Moonesinghe, Duminda Wijeysundera

Journal article  |  2019  |  British Journal of Anaesthesia

BACKGROUND: Clinical indicators are powerful tools to quantify the safety and quality of patient care. Their validity is often unc..

The Fragility Index in peri-operative randomised trials that reported significant mortality effects in adults

L Bertaggia, M Baiardo Redaelli, R Lembo, C Sartini, R Cuffaro, F Corrao, A Zangrillo, G Landoni, R Bellomo

Journal article  |  2019  |  Anaesthesia

Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?

Daniel Cudini, Karen Smith, Stephen Bernard, Michael Stephenson, Emily Andrew, Peter Cameron, Mark Lum, Andrew Udy, S Peake, A Delaney, R Bellomo, PA Cameron, DJ Cooper, A Cross, C Gomersall, C Graham, AM Higgins, A Holdgate, BD Howe, I Jacobs, et al.

Journal article  |  2019  |  Emergency Medicine Australasia

Early dysglycemia and mortality in traumatic brain injury and subarachnoid hemorrhage

Simone Pappacena, Michael Bailey, Luca Cabrini, Giovanni Landoni, Andrew Udy, David Pilcher, Paul Young, Rinaldo Bellomo

Journal article  |  2019  |  Minerva Anestesiologica

BACKGROUND: Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are the most common causes of severe acute brain injury..

The incidence, characteristics, outcomes and associations of small short-term point-of-care creatinine increases in critically ill patients

Lisa Toh, Laurent Bitker, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Critical Care

Furosemide reverses medullary tissue hypoxia in ovine septic acute kidney injury

Naoya Iguchi, Yugeesh R Lankadeva, Trevor A Mori, Eduardo A Osawa, Salvatore L Cutuli, Roger G Evans, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

In experimental sepsis, the rapid development of renal medullary hypoxia precedes the development of acute kidney injury (AKI) and..

The hospital-based evaluation of laxative prophylaxis in ICU (HELP-ICU): A pilot cluster-crossover randomized clinical trial

Tyler Hay, Adam M Deane, Tom Rechnitzer, Kate Fetterplace, Rebecca Reilly, Melissa Ankravs, Michael Bailey, Timothy Fazio, James Anstey, Rohit D'Costa, Jeffrey J Presneill, Christopher M Maclsaac, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Critical Care

Constipation, diarrhea, and prophylactic laxative bowel regimens in the critically ill: A systematic review and meta-analysis

Tyler Hay, Rinaldo Bellomo, Tom Rechnitzer, Emily See, Yasmine Ali Abdelhamid, Adam M Deane

Journal article  |  2019  |  Journal of Critical Care

Epidemiology and outcomes of acute liver failure in Australia

Penelope Hey, Timothy P Hanrahan, Marie Sinclair, Adam G Testro, Peter W Angus, Adam Peterson, Stephen Warrillow, Rinaldo Bellomo, Marcos Perini, Graham Starkey, Robert M Jones, Michael Fink, Tess McClure, Paul Gow

Journal article  |  2019  |  World Journal of Hepatology

A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP-I trial

Michael C Reade, Denese C Marks, Rinaldo Bellomo, Renae Deans, Daniel J Faulke, John F Fraser, David J Gattas, Anthony D Holley, David O Irving, Lacey Johnson, Bronwyn L Pearse, Alistair G Royse, Janet Wong, Laurence Weinberg, Glenn Eastwood, Leah Peck, Helen Young, Sofia Sidiropoulos, Sarah Baulch, Amanda Dalyell, et al.

Journal article  |  2019  |  Transfusion

BACKGROUND: Cryopreservation extends platelet (PLT) shelf life from 5 to 7 days to 2 to 4 years. However, only 73 patients have be..

Fresh Red Cells for Transfusion in Critically Ill Adults: An Economic Evaluation of the Standard Issue Transfusion Versus Fresher Red-Cell Use in Intensive Care (TRANSFUSE) Clinical Trial

Adam Irving, Alisa Higgins, Bridget Ady, Rinaldo Bellomo, D James Cooper, Craig French, Dashiell Gantner, Anthony Harris, David O Irving, Lynne Murray, Alistair Nichol, Dennis Petrie, Zoe K McQuilten

Journal article  |  2019  |  Critical Care Medicine

Retrospective frailty determination in critical illness from a review of the intensive care unit clinical record

Jai N Darvall, Tristan Boonstra, Jen Norman, Donal Murphy, Michael Bailey, Theodore J Iwashyna, Sean M Bagshaw, Rinaldo Bellomo

Journal article  |  2019  |  Anaesthesia and Intensive Care

Hospital-acquired complications in intensive care unit patients with diabetes: A before-and-after study of a conventional versus liberal glucose control protocol

Nora Luethi, Luca Cioccari, Glenn Eastwood, Peter Biesenbach, Rhys Morgan, Stephanie Sprogis, Helen Young, Leah Peck, Christine Knee Chong, Sandra Moore, Kylie Moon, Elif I Ekinci, Adam M Deane, Rinaldo Bellomo, Johan Martensson

Journal article  |  2019  |  Acta Anaesthesiologica Scandinavica

Characteristics and outcomes of patients with acute liver failure admitted to Australian and New Zealand intensive care units

Stephen Warrillow, Michael Bailey, David Pilcher, Alex Kazemi, Colin McArthur, Paul Young, Rinaldo Bellomo

Journal article  |  2019  |  Internal Medicine Journal

Early Sedation with Dexmedetomidine in Critically Ill Patients

Y Shehabi, BD Howe, R Bellomo, YM Arabi, M Bailey, FE Bass, S Bin Kadiman, CJ McArthur, L Murray, MC Reade, IM Seppelt, J Takala, MP Wise, SA Webb

Journal article  |  2019  |  New England Journal of Medicine

BACKGROUND: Dexmedetomidine produces sedation while maintaining a degree of arousability and may reduce the duration of mechanical..

Renal Cortical Perfusion, Measured by Superb Microvascular Imaging, during Infusion of Norepinephrine in Experimental Cardiopulmonary Bypass

Naoya Iguchi, Yugeesh R Lankadeva, Roger G Evans, Andrew D Cochrane, Bruno Marino, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  American Journal of Respiratory and Critical Care Medicine

Sepsis uncouples serum C-peptide and insulin levels in critically ill patients with type 2 diabetes mellitus

Laurent Bitker, Salvatore L Cutuli, Luca Cioccari, Eduardo A Osawa, Lisa Toh, Nora Luethi, Helen Young, Leah Peck, Glenn M Eastwood, Johan Martensson, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVE: To assess the effects of sepsis and exogenous insulin on C-peptide levels and C-peptide to insulin ratios in intensive ..

Trauma-related admissions to intensive care units in Australia: the influence of Indigenous status on outcomes

Fraser Magee, Anthony Wilson, Michael J Bailey, David Pilcher, Paul J Secombe, Paul Young, Rinaldo Bellomo

Journal article  |  2019  |  Medical Journal of Australia

Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial

Alisa M Higgins, Sandra L Peake, Rinaldo Bellomo, D Jamie Cooper, Anthony Delaney, Anthony H Harris, Belinda D Howe, Alistair D Nichol, Steve A Webb, Patricia J Williams

Journal article  |  2019  |  Critical Care Medicine

In this issue of CCR.

Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Association of Net Ultrafiltration Rate With Mortality Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous Hemodiafiltration A Secondary Analysis of the Randomized Evaluation of Normal vs Augmented Level (RENAL) of Renal Replacement Therapy Trial

Raghavan Murugan, Samantha J Kerti, Chung-Chou H Chang, Martin Gallagher, Gilles Clermont, Paul M Palevsky, John A Kellum, Rinaldo Bellomo

Journal article  |  2019  |  JAMA Network Open

Importance: Net ultrafiltration (NUF) is frequently used to treat fluid overload among critically ill patients, but whether the ra..

Prevalence of low-normal body temperatures and use of active warming in emergency department patients presenting with severe infection

Oliver T Gouldthorpe, David Pilcher, Rinaldo Bellomo, Andrew A Udy

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVE: To describe the prevalence of low-normal body temperatures in emergency department (ED) patients presenting with severe..

Importance of intraoperative oliguria during major abdominal surgery: findings of the Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery trial

Paul S Myles, David R McIlroy, Rinaldo Bellomo, Sophie Wallace

Journal article  |  2019  |  British Journal of Anaesthesia

Sodium bicarbonate therapy for critically ill patients with metabolic acidosis: A scoping and a systematic review

Tomoko Fujii, Andrew Udy, Elisa Licari, Lorena Romero, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Critical Care

Intravenous amino acid therapy for kidney protection in cardiac surgery patients: A pilot randomized controlled trial

Hong Pu, Gordon S Doig, Philippa T Heighes, Matilde J Allingstrup, Andy Wang, John Brereton, Carol Pollock, Douglas Chesher, Rinaldo Bellomo

Journal article  |  2019  |  The Journal of Thoracic and Cardiovascular Surgery

Do we need to stabilise plasma vitamin C samples?

J Collie, R Greaves, R Zakaria, A Deane, R Bellomo

Conference Proceedings  |  2019  |  Clinica Chimica Acta

Fentanyl versus morphine for analgo-sedation in mechanically ventilated adult ICU patients

Andrew Casamento, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Strategies that improve renal medullary oxygenation during experimental cardiopulmonary bypass may mitigate postoperative acute kidney injury

Yugeesh R Lankadeva, Andrew D Cochrane, Bruno Marino, Naoya Iguchi, Sally G Hood, Rinaldo Bellomo, Clive N May, Roger G Evans

Journal article  |  2019  |  Kidney International

Persistent critical illness: baseline characteristics, intensive care course, and cause of death

Jai N Darvall, Tristan Boonstra, Jen Norman, Donal Murphy, Michael Bailey, Theodore J Iwashyna, Sean M Bagshaw, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

OBJECTIVES: Persistent critical illness (PerCI) is associated with high mortality and discharge to institutional care. Little is k..

Vitamin C, Hydrocortisone and Thiamine in Patients with Septic Shock (VITAMINS) trial: study protocol and statistical analysis plan

Tomoko Fujii, Andrew A Udy, Adam M Deane, Nora Luethi, Michael Bailey, Glenn M Eastwood, Daniel Frei, Craig French, Neil Orford, Yahya Shehabi, Paul J Young, Rinaldo Bellomo

Journal article  |  2019  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

BACKGROUND: Septic shock is associated with poor outcomes. Vitamin C (ascorbic acid) is a cellular antioxidant and has anti-inflam..

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The SCARLET Randomized Clinical Trial

Jean-Louis Vincent, Bruno Francois, Igor Zabolotskikh, Mradul Kumar Daga, Jean-Baptiste Lascarrou, Mikhail Y Kirov, Ville Pettila, Xavier Wittebole, Ferhat Meziani, Emmanuelle Mercier, Suzana M Lobo, Philip S Barie, Mark Crowther, Charles T Esmon, Jawed Fareed, Satoshi Gando, Kenneth J Gorelick, Marcel Levi, Jean-Paul Mira, Steven M Opal, et al.

Journal article  |  2019  |  JAMA

Carotid artery and cerebral blood flow during experimental cardiopulmonary resuscitation: A systematic review of the literature

Luca Lucchetta, Timothy N Kwan, Junko Kosaka, Aiko Tanaka, Glenn M Eastwood, Matthew Chan, Johan Martensson, Clive N May, Rinaldo Bellomo

Journal article  |  2019  |  Resuscitation

A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Reducing Mortality

Chiara Sartini, Vladimir Lomivorotov, Manna Pieri, Juan Carlos Lopez-Delgado, Martina Baiardo Redaelli, Ludhmila Hajjar, Antonio Pisano, Valery Likhvantsev, Evgeny Fominskiy, Nikola Bradic, Luca Cabrini, Maxim Novikov, Daniele Avancini, Hynek Riha, Rosalba Lembo, Gordana Gazivoda, Gianluca Paternoster, Chengbin Wang, Simona Tama, Gabriele Alvaro, et al.

Journal article  |  2019  |  Journal of Cardiothoracic and Vascular Anesthesia

The rise of ward monitoring: opportunities and challenges for critical care specialists

Frederic Michard, Rinaldo Bellomo, Andreas Taenzer

Journal article  |  2019  |  Intensive Care Medicine

MAGNESIUM STATUS AND MAGNESIUM THERAPY IN CARDIAC SURGERY: A SYSTEMATIC REVIEW AND META-ANALYSIS FOCUSING ON ARRHYTHMIA PREVENTION

Jessica L Fairley, Ling Zhang, Neil J Glassford, Rinaldo Bellomo

Conference Proceedings  |  2019  |  INTERNAL MEDICINE JOURNAL

Fever control in critically ill adults. An individual patient data meta-analysis of randomised controlled trials

Paul J Young, Rinaldo Bellomo, Gordon R Bernard, Daniel J Niven, Frederique Schortgen, Manoj Saxena, Richard Beasley, Mark Weatherall

Journal article  |  2019  |  Intensive Care Medicine

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis

Jonathan Barnes, Jennifer Hunter, Steve Harris, Manu Shankar-Hari, Elisabeth Diouf, Ib Jammer, Cor Kalkman, Andrew A Klein, Tomas Corcoran, Stefan Dieleman, Michael PW Grocott, Michael G Mythen

Journal article  |  2019  |  British Journal of Anaesthesia

Declining mortality of cirrhotic patients requiring admission to intensive care units for serious infections: A bi-national cohort study

Ammar Majeed, Michael Bailey, Avik Majumdar, William Kemp, Rinaldo Bellomo, David Pilcher, Stuart Roberts

Conference Proceedings  |  2019  |  Journal of Hepatology

Blood Pressure and Early Mobilization After Total Hip and Knee Replacements: A Pilot Study on the Impact of Midodrine Hydrochloride.

Michael Smits, Sandra Lin, Jessica Rahme, Michael Bailey, Rinaldo Bellomo, Andrew Hardidge

Journal article  |  2019  |  JBJS Open Access

Background: Early mobilization is an important therapeutic goal after total knee replacement and total hip replacement. Orthostati..

Modern Critical Care Endocrinology and Its Impact on Critical Care Medicine Preface

Rinaldo Bellomo

Journal article  |  2019  |  Critical Care Clinics

Assessment of agreement and interchangeability between the TEG5000 and TEG6S thromboelastography haemostasis analysers: a prospective validation study

P Lloyd-Donald, L Churilov, F Zia, R Bellomo, G Hart, P McCall, J Martensson, N Glassford, L Weinberg

Journal article  |  2019  |  BMC Anesthesiology

Volatile Anesthetics versus Total Intravenous Anesthesia for Cardiac Surgery

Giovanni Landoni, Vladimir V Lomivorotov, Caetano Nigro Neto, Fabrizio Monaco, Vadim V Pasyuga, Nikola Bradic, Rosalba Lembo, Gordana Gazivoda, Valery V Likhvantsev, Chong Lei, Andrey Lozovskiy, Nora Di Tomasso, Nazar AR Bukamal, Fernanda S Silva, Andrey E Bautin, Jun Ma, Martina Crivellari, Ahmed MGA Farag, Nikolay S Uvaliev, Cristiana Carollo, et al.

Journal article  |  2019  |  New England Journal of Medicine

Predictors and Outcomes of Cardiac Surgery-Associated Delirium. A Single Centre Retrospective Cohort Study

Daryl Jones, George Matalanis, Johan Martensson, Raymond Robbins, Margaret Shaw, Siven Seevanayagam, Dean Cowie, Rinaldo Bellomo

Journal article  |  2019  |  Heart, Lung and Circulation

Effect of communication skills training on outcomes in critically ill patients with life-limiting illness referred for intensive care management: a before-and-after study

Neil R Orford, Sharyn Milnes, Nicholas Simpson, Gerry Keely, Tania Elderkin, Allison Bone, Peter Martin, Rinaldo Bellomo, Michael Bailey, Charlie Corke

Journal article  |  2019  |  BMJ Supportive & Palliative Care

Non-invAsive VentIlation for early General wArd respiraTory failurE (NAVIGATE): A multicenter randomized controlled study. Protocol and statistical analysis plan

Luca Cabrini, Claudia Brusasco, Agostino Roasio, Francesco Corradi, Pasquale Nardelli, Matteo Filippini, Virginia Cotticelli, Alessandro Belletti, Lorenzo Ferrara, Elio Antonucci, Martina Baiardo Redaelli, Marco Lattuada, Sergio Colombo, Luigi Olper, Giuseppe Ponzetta, Sofia Ananiadou, Giacomo Monti, Luca Severi, Giulia Maj, Giuseppe Giardina, et al.

Journal article  |  2019  |  Contemporary Clinical Trials

Reported practice of temperature adjustment (alpha-stat v pH-stat) for arterial blood gases measurement among investigators from two major cardiac arrest trials

Glenn M Eastwood, Niklas Nielsen, Alistair D Nichol, Markus B Skrifvars, Craig French, Rinaldo Bellomo

Journal article  |  2019  |  Critical Care and Resuscitation

BACKGROUND: Two major cardiac arrest trials are evaluating different strategies that may potentially mitigate neurological injury ..

The normal cardiac index in older healthy individuals: a scoping review

Luca Cioccari, Nora Luethi, Neil J Glassford, Rinaldo Bellomo

Journal article  |  2019  |  Critical Care and Resuscitation

OBJECTIVE: Despite the growing number of older patients having major surgery, the normal resting values for the cardiac index of o..

Blood Pressure Covariance Not Accounted for in Angiotensin II for the Treatment of High-Output Shock 3 Subgroup Analysis Reply

Rinaldo Bellomo, Stew Kroll, Lakhmir S Chawla, George F Tidmarsh

Journal article  |  2019  |  Critical Care Medicine

Renal perfusion, oxygenation, and sympathetic nerve activity during volatile or intravenous general anaesthesia in sheep

Naoya Iguchi, Junko Kosaka, Lindsea C Booth, Yoko Iguchi, Roger G Evans, Rinaldo Bellomo, Clive N May, Yugeesh R Lankadeva

Journal article  |  2019  |  British Journal of Anaesthesia

Urinary Biomarkers may Complement the Cleveland Score for Prediction of Adverse Kidney Events After Cardiac Surgery: A Pilot Study

Christian Albert, Michael Haase, Annemarie Albert, Siegfried Kropf, Rinaldo Bellomo, Sabine Westphal, Mark Westerman, Ruediger Christian Braun-Dullaeus, Anja Haase-Fielitz

Journal article  |  2019  |  Annals of Laboratory Medicine

BACKGROUND: The ability of urinary biomarkers to complement established clinical risk prediction models for postoperative adverse ..

Conservative versus conventional oxygen therapy for cardiac surgical patients: A before-and-after study

Glenn M Eastwood, Matthew J Chan, Leah Peck, Helen Young, Johan Martensson, Neil J Glassford, Hidetoshi Kagaya, Satoshi Suzuki, Sean Galvin, George Matalanis, Rinaldo Bellomo

Journal article  |  2019  |  Anaesthesia and Intensive Care

Avoiding hypoxaemia is considered crucial in cardiac surgery patients admitted to the intensive care unit (ICU). However, avoiding..

EFFECTS OF CLONIDINE ON THE CARDIOVASCULAR, RENAL, AND INFLAMMATORY RESPONSES TO EXPERIMENTAL BACTEREMIA

Paolo Calzavacca, Lindsea C Booth, Yugeesh R Lankadeva, Simon R Bailey, Louise M Burrell, Michael Bailey, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  SHOCK

In this issue of CCR.

Rinaldo Bellomo

Journal article  |  2019  |  Critical Care and Resuscitation

"Likely overassistance" during invasive pressure support ventilation in patients in the intensive care unit: a multicentre prospective observational study

Wisam Al-Bassam, Fabian Dade, Michael Bailey, Glenn Eastwood, Eduardo Osawa, Chris Eyeington, James Anesty, George Yi, Jolene Ralph, Nima Kakho, Vishnu Kurup, Elisa Licari, Emma C King, Cameron Knott, Timothy Chimunda, Julie Smith, Ashwin Subramaniam, Mallikarjuna Reddy, Cameron Green, Geoffrey Parkin, et al.

Journal article  |  2019  |  Critical Care and Resuscitation

OBJECTIVE: To evaluate the prevalence of "likely overassistance" (categorised by respiratory rate [RR] ≤ 17 breaths/min or rapid s..

Sex and mortality in septic severe acute kidney injury

Zachary O'Brien, Alan Cass, Louise Cole, Simon Finfer, Martin Gallagher, Colin McArthur, Shay McGuiness, John Myburgh, Rinaldo Bellomo, Johan A Martensson

Journal article  |  2019  |  Journal of Critical Care

Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial

Markus B Skrifvars, Elizabeth Moore, Johan Martensson, Michael Bailey, Craig French, Jeffrey Presneill, Alistair Nichol, Lorraine Little, Jacques Duranteau, Olivier Huet, Samir Haddad, Yaseen Arabi, Colin McArthur, David J Cooper, Rinaldo Bellomo

Journal article  |  2019  |  Acta Anaesthesiologica Scandinavica

Sepsis-induced acute kidney injury: A disease of the microcirculation

Shuai Ma, Roger G Evans, Naoya Iguchi, Marianne Tare, Helena C Parkington, Rinaldo Bellomo, Clive N May, Yugeesh R Lankadeva

Journal article  |  2019  |  Microcirculation

The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis, a multicentre observational study (ARISE FLUIDS observational study): Rationale, methods and analysis plan

Gerben Keijzers, Stephen PJ Macdonald, Andrew A Udy, Glenn Arendts, Michael Bailey, Rinaldo Bellomo, Gabriel E Blecher, Jonathon Burcham, Anthony Delaney, Andrew R Coggins, Daniel M Fatovich, John F Fraser, Amanda Harley, Peter Jones, Fran Kinnear, Katya May, Sandra Peake, David McD Taylor, Julian Williams, Patricia Williams

Journal article  |  2019  |  Emergency Medicine Australasia

Rapid response team review of hemodynamically unstable ward patients: The accuracy of cardiac index assessment

Christopher T Eyeington, Patryck Lloyd-Donald, Matthew J Chan, Glenn M Eastwood, Helen Youn, Leah Peck, Daryl A Jones, Rinaldo Bellomo

Journal article  |  2019  |  Journal of Critical Care

Why do multicenter randomized controlled trials not confirm the positive findings of single center randomized controlled trials in acute care?

Giovanni Landoni, Marina Pieri, Paul J Young, Rinaldo Bellomo

Journal article  |  2019  |  Minerva Anestesiologica

Persistent decrease of renal functional reserve in patients after cardiac surgery-associated acute kidney injury despite clinical recovery

Faeq Husain-Syed, Fiorenza Ferrari, Aashish Sharma, Tommaso Hinna Danesi, Percia Bezerra, Salvador Lopez-Giacoman, Sara Samoni, Massimo de Cal, Valentina Corradi, Grazia Maria Virzi, Silvia De Rosa, Maria Jimena Mucino Bermejo, Carla Estremadoyro, Gianluca Villa, Jose J Zaragoza, Carlotta Caprara, Alessandra Brocca, Horst-Walter Birk, Hans-Dieter Walmrath, Werner Seeger, et al.

Journal article  |  2019  |  Nephrology Dialysis Transplantation

Preface

C Ronco, R Bellomo, JA Kellum, Z Ricci

Book  |  2019

Is research from databases reliable? No

Anders Perner, Rinaldo Bellomo, Morten Hylander Moller

Journal article  |  2019  |  Intensive Care Medicine

Modern technology-derived normative values for cerebral tissue oxygen saturation in adults

Christopher T Eyeington, Paolo Ancona, Eduardo A Osawa, Salvatore L Cutuli, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2019  |  Anaesthesia and Intensive Care

Modern near-infrared spectroscopy technology is increasingly adopted to measure cerebral tissue oxygen saturation. However, the no..

The Incidence, Predictors and Outcomes of QTC Prolongation in Critically Ill Patients

Hollie Russell, Rinaldo Bellomo

Conference Proceedings  |  2019  |  Australian Critical Care

Long-term risk of adverse outcomes after acute kidney injury: a systematic review and meta-analysis of cohort studies using consensus definitions of exposure

Emily J See, Kushani Jayasinghe, Neil Glassford, Michael Bailey, David W Johnson, Kevan R Polkinghorne, Nigel D Toussaint, Rinaldo Bellomo

Conference Proceedings  |  2019  |  Kidney International

The ten pitfalls of lactate clearance in sepsis

Glenn Hernandez, Rinaldo Bellomo, Jan Bakker

Journal article  |  2019  |  Intensive Care Medicine

Outcome of Acetaminophen-Induced Acute Liver Failure Managed Without Intracranial Pressure Monitoring or Transplantation

Jennifer Porteous, Luca Cioccari, Paolo Ancona, Eduardo Osawa, Kelly Jones, Paul Gow, Peter Angus, Stephen Warrillow, Rinaldo Bellomo

Journal article  |  2019  |  Liver Transplantation

Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury

Yugeesh R Lankadeva, Junko Kosaka, Naoya Iguchi, Roger G Evans, Lindsea C Booth, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  Critical Care Medicine

Vasoactive Drugs, Renal Function, and Acute Kidney Injury

YR Lankadeva, RG Evans, R Bellomo, CN May

Book Chapter  |  2019

Blood Purification for Sepsis

V Cantaluppi, M Marengo, ZY Peng, JA Kellum, R Bellomo, C Ronco

Book Chapter  |  2019

Control of Confounding and Reporting of Results in Causal Inference Studies Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals

David J Lederer, Scott C Bell, Richard D Branson, James D Chalmers, Rachel Marshall, David M Maslove, David E Ost, Naresh M Punjabi, Michael Schatz, Alan R Smyth, Paul W Stewart, Samy Suissa, Alex A Adjei, Cezmi A Akdis, Elie Azoulay, Jan Bakker, Zuhair K Ballas, Philip G Bardin, Esther Barreiro, Rinaldo Bellomo, et al.

Journal article  |  2019  |  Annals of the American Thoracic Society

Oxygenation targets in acutely ill patients: still a matter of debate

Daniel Martin, Michael Grocott, Rinaldo Bellomo

Journal article  |  2018  |  The Lancet

Prediction of tracheostomy in critically ill trauma patients: a systematic review

Andrew J Casamento, Bronwyn Bebee, Neil J Glassford, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

Haemodynamic effects of cold versus warm fluid bolus in healthy volunteers: a randomised crossover trial

Olof Wall, Lars Ehrenberg, Eva Joelsson-Alm, Johan Martensson, Rinaldo Bellomo, Christer Svensen, Maria Cronhjort

Journal article  |  2018  |  Critical Care and Resuscitation

The effect on survival from the use of a saphenous vein graft during coronary bypass surgery: a large cohort study

Alistair Royse, Zulfayandi Pawanis, David Canty, Jared Ou-Young, David Eccleston, Andrew Ajani, Christopher M Reid, Rinaldo Bellomo, Colin Royse

Journal article  |  2018  |  European Journal of Cardio-Thoracic Surgery

Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial

Stephen PJ Macdonald, Gerben Keijzers, David McD Taylor, Frances Kinnear, Glenn Arendts, Daniel M Fatovich, Rinaldo Bellomo, David McCutcheon, John F Fraser, Juan-Carlos Ascencio-Lane, Sally Burrows, Edward Litton, Amanda Harley, Matthew Anstey, Ashes Mukherjee

Journal article  |  2018  |  Intensive Care Medicine

The impact of non-blinding in critical care medicine trials

M Baiardo Redaelli, A Belletti, G Monti, R Lembo, A Ortalda, G Landoni, R Bellomo

Journal article  |  2018  |  Journal of Critical Care

Predictors of return to work in survivors of critical illness

Carol L Hodgson, Kimberley J Haines, Michael Bailey, Jonathan Barrett, Rinaldo Bellomo, Tracey Bucknall, Belinda J Gabbe, Alisa M Higgins, Theodore J Iwashyna, Julian Hunt-Smith, Lynne J Murray, Paul S Myles, Jennie Ponsford, David Pilcher, Andrew A Udy, Craig Walker, Meredith Young, DJ Jamie Cooper

Journal article  |  2018  |  Journal of Critical Care

What should we target after TARGET?

Paul J Young, Rinaldo Bellomo, Marianne J Chapman, Adam M Deane, Sandra L Peake

Journal article  |  2018  |  Critical Care and Resuscitation

Perioperative renal protection

Emmanuel Canet, Rinaldo Bellomo

Journal article  |  2018  |  Current Opinion in Critical Care

Timing of onset of persistent critical illness: a multi-centre retrospective cohort study

Sean M Bagshaw, Henry T Stelfox, Theodore J Iwashyna, Rinaldo Bellomo, Dan Zuege, Xioaming Wang

Journal article  |  2018  |  Intensive Care Medicine

Alterations in regional kidney oxygenation during expansion of extracellular fluid volume in conscious healthy sheep

Yugeesh R Lankadeva, Roger G Evans, Junko Kosaka, Lindsea C Booth, Naoya Iguchi, Rinaldo Bellomo, Clive N May

Journal article  |  2018  |  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Intensive care implications of epidemic thunderstorm asthma

Jai N Darvall, Matthew Durie, David Pitcher, Geoffrey Wigmore, Craig French, Dharshi Karalapillai, Forbes McGain, Edward Newbigin, Timothy Byrne, Vineet Sarode, Ben Gelbart, Andrew Casamento, John Dyett, Ashley Crosswell, Joseph Vetro, Joseph McCaffrey, Gopal Taori, Ashwin Subramaniam, Christopher Macisaac, Anthony Cross, et al.

Journal article  |  2018  |  Critical Care and Resuscitation

qSOFA as predictor of mortality and prolonged ICU admission in Emergency Department patients with suspected infection

Emmanuel Canet, David McD Taylor, Richard Khor, Vivek Krishnan, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Renal replacement therapy in the ICU: intermittent hemodialysis, sustained low-efficiency dialysis or continuous renal replacement therapy?

Amanda Ying Wang, Rinaldo Bellomo

Journal article  |  2018  |  Current Opinion in Critical Care

Laboratory alerts to guide early intensive care team review in surgical patients: A feasibility, safety, and efficacy pilot randomized controlled trial

Rinaldo Bellomo, Matthew Chan, Christopher Guy, Helena Proimos, Federica Franceschi, Marco Crisman, Aniket Nadkarni, Paolo Ancona, Kevin Pan, Francesca Di Muzio, Barbara Presello, James Bailey, Marcus Young, Graeme K Hart

Journal article  |  2018  |  Resuscitation

Acute glycemic control in diabetics. How sweet is oprimal? Pro: Sweeter is better in diabetes

Rinaldo Bellomo

Journal article  |  2018  |  Journal of Intensive Care

Energy-Dense versus Routine Enteral Nutrition in the Critically Ill

Marianne Chapman, Sandra L Peake, Rinaldo Bellomo, Andrew Davies, Adam Deane, Michael Horowitz, Sally Hurford, Kylie Lange, Lorraine Little, Diane Mackle, Stephanie O'Connor, Jeffrey Presneill, Emma Ridley, Patricia Williams, Paul Young

Journal article  |  2018  |  New England Journal of Medicine

Changes in bone mineral density in women before critical illness: a matched control nested cohort study

Neil R Orford, Michael Bailey, Rinaldo Bellomo, Julie A Pasco, David J Cooper, Mark A Kotowicz

Journal article  |  2018  |  Archives of Osteoporosis

Discussion about "Association of frailty with short-term outcomes, organ support and resource use in critically ill patients"

Jai N Darvall, David Pilcher, Rinaldo Bellomo, Fernando G Zampieri, Theodore J Iwashyna, Elizabeth M Viglianti, Marcio Soares

Journal article  |  2018  |  Intensive Care Medicine

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: renal endpoints

DR McIlroy, R Bellomo, FT Billings, K Karkouti, JR Prowle, AD Shaw, PS Myles

Journal article  |  2018  |  British Journal of Anaesthesia

Changes in Temperature Management of Cardiac Arrest Patients Following Publication of the Target Temperature Management Trial*

Ryan Salter, Michael Bailey, Rinaldo Bellomo, Glenn Eastwood, Andrew Goodwin, Niklas Nielsen, David Pilcher, Alistair Nichol, Manoj Saxena, Yahya Shehabi, Paul Young

Journal article  |  2018  |  Critical Care Medicine

Small volume resuscitation with 20% albumin in intensive care: physiological effects: The SWIPE randomised clinical trial

Johan Martensson, Shailesh Bihari, Jonathan Bannard-Smith, Neil J Glassford, Patryck Lloyd-Donald, Luca Cioccari, Nora Luethi, Aiko Tanaka, Marco Crisman, Nicolas Rey de Castro, Marcus Ottochian, Agnes Huang, Maria Cronhjort, Andrew D Bersten, Shivesh Prakash, Michael Bailey, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2018  |  Intensive Care Medicine

Angiotensin converting enzyme defects in shock: implications for future therapy

Lakhmir S Chawla, Steve Chen, Rinaldo Bellomo, George F Tidmarsh

Journal article  |  2018  |  Critical Care

Hospital variability of postoperative sepsis and sepsis-related mortality after elective coronary artery bypass grafting surgery

Lixin Ou, Jack Chen, Arthas Flabouris, Ken Hillman, Michael Parr, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

A Double-Blind Randomized Controlled Trial of High Cutoff Versus Standard Hemofiltration in Critically Ill Patients With Acute Kidney Injury

Rafidah Atan, Leah Peck, John Prowle, Elisa Licari, Glenn M Eastwood, Markus Storr, Hermann Goehl, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care Medicine

Liberal Versus Restrictive Intravenous Fluid Therapy for Early Septic Shock: Rationale for a Randomized Trial

Wesley H Self, Matthew W Semler, Rinaldo Bellomo, Samuel M Brown, Bennett P deboisblanc, Matthew C Exline, Adit A Ginde, Colin K Grissom, David R Janz, Alan E Jones, Kathleen D Liu, Stephen PJ Macdonald, Chadwick D Miller, Pauline K Park, Lora A Reineck, Todd W Rice, Jay S Steingrub, Daniel Talmor, Donald M Yealy, Ivor S Douglas, et al.

Journal article  |  2018  |  Annals of Emergency Medicine

Restrictive or Liberal Fluid Therapy for Major Abdominal Surgery Reply

Paul S Myles, Rinaldo Bellomo

Journal article  |  2018  |  New England Journal of Medicine

Net ultrafiltration intensity and mortality in critically ill patients with fluid overload

Raghavan Murugan, Vikram Balakumar, Samantha J Kerti, Priyanka Priyanka, Chung-Chou H Chang, Gilles Clermont, Rinaldo Bellomo, Paul M Palevsky, John A Kellum

Journal article  |  2018  |  Critical Care

Magnesium sulfate therapy after cardiac surgery: a before-and-after study comparing strategies involving bolus and continuous infusion

Eduardo Osawa, Peter Biesenbach, Salvatore L Cutuli, Glenn M Eastwood, Johan Martensson, George Matalanis, Jessica Fairley, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

PREDICTION OF THE OUTCOME OF ACUTE RENAL REPLACEMENT THERAPY

Y Wang, M Gallagher, Q Li, R Bellomo

Conference Proceedings  |  2018  |  NEPHROLOGY

The relationship between the change in central venous pressure and intravenous fluid volume in patients presenting to the emergency department with septic shock

Benjamin Reddi, Mark Finnis, Andrew A Udy, Matthew Maiden, Anthony Delaney, Rinaldo Bellomo, Sandra Peake

Journal article  |  2018  |  Intensive Care Medicine

The effect of protamine dosing variation on bleeding and transfusion after heparinisation for cardiopulmonary bypass

Stephen A Kunz, Lachlan F Miles, Damian J Ianno, Kelly L Mirowska-Allen, George Matalanis, Rinaldo Bellomo, Siven Seevanayagam

Journal article  |  2018  |  Perfusion

Urinary neutrophil gelatinase-associated lipocalin-guided risk assessment for major adverse kidney events after open-heart surgery

Christian Albert, Annemarie Albert, Rinaldo Bellomo, Siegfried Kropf, Prasad Devarajan, Sabine Westphal, Hassina Baraki, Ingo Kutschka, Christian Butter, Michael Haase, Anja Haase-Fielitz

Journal article  |  2018  |  Biomarkers in Medicine

Understanding the rationale for parenteral ascorbate (vitamin C) during an acute inflammatory reaction: a biochemical perspective

Robert McNamara, Adam M Deane, James Anstey, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

Body temperature measurement methods and targets in Australian and New Zealand intensive care units

Salvatore L Cutuli, Eduardo A Osawa, Neil J Glassford, David Marshall, Christopher T Eyeington, Glenn M Eastwood, Paul J Young, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

In this issue of CCR.

Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

PROGNOSTIC SIGNIFICANCE OF LOW LEVEL OF BLOOD GLUCOSE IN SEVERE ACUTE KIDNEY INJURY: A SECONDARY ANALYSIS FROM THE RENAL STUDY

Y Xie, J Lin, M Gallagher, R Bellomo, M Jardine, A Wang

Conference Proceedings  |  2018  |  NEPHROLOGY

Stability of intravenous vitamin C solutions: a technical report

Anitra Carr, Christina Wohlrab, Paul Young, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

Intravenous fluid therapy in critically ill adults

Simon Finfer, John Myburgh, Rinaldo Bellomo

Journal article  |  2018  |  Nature Reviews Nephrology

A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol

Paul J Young, Sean M Bagshaw, Andrew Forbes, Alistair Nichol, Stephen E Wright, Rinaldo Bellomo, Michael J Bailey, Richard W Beasley, Glenn M Eastwood, Marino Festa, David Gattas, Frank van Haren, Edward Litton, Paul R Mouncey, Leanlove Navarra, David Pilcher, Diane M Mackie, Colin J McArthur, Shay P McGuinness, Manoj K Saxena, et al.

Journal article  |  2018  |  Critical Care and Resuscitation

Progress in Prevention and Treatment of Acute Kidney Injury Moving Beyond Kidney Attack

John A Kellum, Rinaldo Bellomo, Claudio Ronco

Journal article  |  2018  |  JAMA

Urinary NGAL-guided risk assessment for adverse kidney-related events after open heart surgery

A Haase-Fielitz, C Albert, A Albert, R Bellomo, S Kropf, P Devarajan, S Westphal, H Baraki, I Kutschka, C Butter, M Haase

Conference Proceedings  |  2018  |  EUROPEAN HEART JOURNAL

Late organ failures in patients with prolonged intensive care unit stays

Elizabeth M Viglianti, Rachel Kramer, Andrew J Admon, Michael W Sjoding, Carol L Hodgson, Rinaldo Bellomo, Theodore J Iwashyna

Journal article  |  2018  |  Journal of Critical Care

The systemic inflammatory response syndrome criteria and their differential association with mortality

Kirsi-Maija Kaukonen, Michael Bailey, David Pitcher, D James Cooper, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Should hydroxyethyl starch be banned? - Authors' reply

Ian Roberts, Haleema Shakur, Rinaldo Bellomo, Julian Bion, Simon Finfer, Beverley Hunt, John Myburgh, Anders Perner, Konrad Reinhart

Journal article  |  2018  |  The Lancet

In reply.

L Weinberg, Mhg Li, L Churilov, R Bellomo

Journal article  |  2018  |  Anaesthesia and intensive care

Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery

PS Myles, R Bellomo, T Corcoran, A Forbes, P Peyton, D Story, C Christophi, K Leslie, S McGuinness, R Parke, J Serpell, MTV Chan, T Painter, S McCluskey, G Minto, S Wallace

Journal article  |  2018  |  New England Journal of Medicine

Ventilation management in Victorian intensive care unit patients without acute respiratory distress syndrome

Christopher T Eyeington, Neil J Glassford, Jai Darvall, Andrew Casamento, Tim Haydon, Gopal Taori, Cameron Knott, Forbes McGain, Joseph Vetro, Nick Simpson, Vineet Sarode, Angus Richardson, Charles Dunnachie, Marco Crisman, Jason Musci, Nicholas Woinarski, Rohan Lynham, Glenn M Eastwood, Rinaldo Bellomo, Dharshi Karalapillai

Journal article  |  2018  |  Critical Care and Resuscitation

Characteristics, incidence and outcome of patients admitted to intensive care unit with Guillain-Barre syndrome in Australia and New Zealand

Paolo Ancona, Michael Bailey, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Urinary biomarkers may provide prognostic information for subclinical acute kidney injury after cardiac surgery

Christian Albert, Annemarie Albert, Johanna Kube, Rinaldo Bellomo, Nicholas Wettersten, Hermann Kuppe, Sabine Westphal, Michael Haase, Anja Haase-Fielitz

Journal article  |  2018  |  The Journal of Thoracic and Cardiovascular Surgery

Characteristics, incidence, and outcome of patients admitted to the intensive care unit with myasthenia gravis

Wisam Al-bassam, Mark Kubicki, Michael Bailey, Laurence Walker, Paul Young, David V Pilcher, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Influence of ward round order on critically ill patient outcomes

Steve Evans, Jai Darvall, Alexandra Gorelik, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial

Menaka Pai, Neill KJ Adhikari, Marlies Ostermann, Diane Heels-Ansdell, James D Douketis, Yoanna Skrobik, Ismael Qushmaq, Maureen Meade, Gordon Guyatt, William Geerts, Michael W Walsh, Mark A Crowther, Jan O Friedrich, Lisa Burry, Rinaldo Bellomo, Nilton Brendao da Silva, Rubens Costa Filho, Michael J Cox, Suzana Alves Silva, Deborah J Cook

Journal article  |  2018  |  PLOS ONE

Pharmacokinetics of Magnesium Bolus Therapy in Cardiothoracic Surgery

Peter Biesenbach, Johan Martensson, Luca Lucchetta, Ravi Bangia, Jessica Fairley, Irmelin Jansen, George Matalanis, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Cardiothoracic and Vascular Anesthesia

Paediatric sequential organ failure assessment score (pSOFA): a plea for the world-wide collaboration for consensus

Tatsuya Kawasaki, Nobuaki Shime, Lahn Straney, Rinaldo Bellomo, Graeme MacLaren, David Pilcher, Luregn J Schlapbach

Journal article  |  2018  |  Intensive Care Medicine

Effect of active temperature management on mortality in intensive care unit patients

Jonathan Dallimore, Stefan Ebmeier, Darmiga Thayabaran, Rinaldo Bellomo, Gordon Bernard, Frederique Schortgen, Manoj Saxena, Richard Beasley, Mark Weatherall, Paul Young

Journal article  |  2018  |  Critical Care and Resuscitation

Repeated sensor use for regional cerebral oxygenation measurements by near-infrared spectroscopy: a technical report

Paolo Ancona, Christopher T Eyeington, Salvatore L Cutuli, Neil J Glassford, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

Impact of unit-wide chlorhexidine bathing in intensive care on bloodstream infection and drug-resistant organism acquisition

Karen F Urbancic, Johan Martensson, Neil Glassford, Christopher Eyeington, Raymond Robbins, Peter B Ward, Darren Williams, Paul DR Johnson, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

The Presence of Diabetes and Higher HbA(1c) Are Independently Associated With Adverse Outcomes After Surgery

Priscilla H Yong, Laurence Weinberg, Niloufar Torkamani, Leonid Churilov, Raymond J Robbins, Ronald Ma, Rinaldo Bellomo, Que T Lam, James D Burns, Graeme K Hart, Jeremy F Lew, Johan Martensson, David Story, Andrew N Motley, Douglas Johnson, Jeffrey D Zajac, Elif I Ekinci

Journal article  |  2018  |  Diabetes Care

Epinephrine and short-term survival in cardiogenic shock: an individual data meta-analysis of 2583 patients

Valentine Leopold, Etienne Gayat, Romain Pirracchio, Jindrich Spinar, Jiri Parenica, Tuukka Tarvasmaki, Johan Lassus, Veli-Pekka Harjola, Sebastien Champion, Faiez Zannad, Serafina Valente, Philip Urban, Horng-Ruey Chua, Rinaldo Bellomo, Batric Popovic, Dagmar M Ouweneel, Jose PS Henriques, Gregor Simonis, Bruno Levy, Antoine Kimmoun, et al.

Journal article  |  2018  |  Intensive Care Medicine

Renal replacement therapy intensity for acute kidney injury and recovery to dialysis independence: a systematic review and individual patient data meta-analysis

Ying Wang, Martin Gallagher, Qiang Li, Serigne Lo, Alan Cass, Simon Finfer, John Myburgh, Catherine Bouman, Robert Faulhaber-Walter, John A Kellum, Pual M Palevsky, Claudio Ronco, Patrick Saudan, Ashita Tolwani, Rinaldo Bellomo

Journal article  |  2018  |  Nephrology Dialysis Transplantation

Sample size calculations for cluster randomised crossover trials in Australian and New Zealand intensive care research

Sarah J Arnup, Joanne E McKenzie, David Pitcher, Rinaldo Bellomo, Andrew B Forbes

Journal article  |  2018  |  Critical Care and Resuscitation

Early glycemia and mortality in critically ill septic patients: Interaction with insulin-treated diabetes

Fraser Magee, Michael Bailey, David V Pilcher, Johan Martensson, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II

James A Tumlin, Raghavan Murugan, Adam M Deane, Marlies Ostermann, Laurence W Busse, Kealy R Ham, Kianoush Kashani, Harold M Szerlip, John R Prowle, Azra Bihorac, Kevin W Finkel, Alexander Zarbock, Lui G Forni, Shannan J Lynch, Jeff Jensen, Stew Kroll, Lakhmir S Chawla, George F Tidmarsh, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care Medicine

\ Liberal Glucose Control in ICU Patients With Diabetes: A Before-and-After Study

Nora Luethi, Luca Cioccari, Peter Biesenbach, Luca Lucchetta, Hidetoshi Kagaya, Rhys Morgan, Francesca Di Muzio, Barbara Presello, Duaa Gaafar, Alison Hay, Marco Crisman, Roisin Toohey, Hollie Russell, Neil J Glassford, Glenn M Eastwood, Elif I Ekinci, Adam M Deane, Rinaldo Bellomo, Johan Martensson

Journal article  |  2018  |  Critical Care Medicine

Sedation Intensity in the First 48 Hours of Mechanical Ventilation and 180-Day Mortality: A Multinational Prospective Longitudinal Cohort Study

Yahya Shehabi, Rinaldo Bellomo, Suhaini Kadiman, Lian Kah Ti, Belinda Howe, Michael C Reade, Tien Meng Khoo, Anita Alias, Yu-Lin Wong, Amartya Mukhopadhyay, Colin McArthur, Ian Seppelt, Steven A Webb, Maja Green, Michael J Bailey

Journal article  |  2018  |  Critical Care Medicine

The Melbourne epidemic thunderstorm asthma event 2016: an investigation of environmental triggers, effect on health services, and patient risk factors

Francis Thien, Paul J Beggs, Danny Csutoros, Jai Darvall, Mark Hew, Janet M Davies, Philip G Bardin, Tony Bannister, Sara Barnes, Rinaldo Bellomo, Timothy Byrne, Andrew Casamento, Matthew Conron, Anthony Cross, Ashley Crosswell, Jo A Douglass, Matthew Durie, John Dyett, Elizabeth Ebert, Bircan Erbas, et al.

Journal article  |  2018  |  The Lancet Planetary Health

BACKGROUND: A multidisciplinary collaboration investigated the world's largest, most catastrophic epidemic thunderstorm asthma eve..

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Matthew J Maiden, Mark E Finnis, Sandra Peake, Simon McRae, Anthony Delaney, Michael Bailey, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care

A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients

SJ Ebmeier, M Barker, M Bacon, RC Beasley, R Bellomo, C Knee Chong, GM Eastwood, J Gilchrist, H Kagaya, J Pilcher, SK Reddy, E Ridgeon, N Sarma, S Spragas, A Tanaka, M Tweedie, M Weatherall, PJ Young

Journal article  |  2018  |  Anaesthesia and Intensive Care

Reply to: The problem of using standardised base excess

Laurence Weinberg, David Story, Rinaldo Bellomo

Journal article  |  2018  |  Perfusion

Plasma-Lyte 148 vs. Hartmann's solution for cardiopulmonary bypass pump prime: a prospective double-blind randomized trial

Laurence Weinberg, Elizabeth Chiam, James Hooper, Frank Liskaser, Angela Kim Hawkins, Denise Massie, Andrew Ellis, Chong O Tan, David Story, Rinaldo Bellomo

Journal article  |  2018  |  Perfusion

Non-invasive estimation of cardiac index in healthy volunteers

CT Eyeington, P Ancona, L Cioccari, N Luethi, NJ Glassford, GM Eastwood, HK Proimos, F Franceschi, MJ Chan, D Jones, R Bellomo

Journal article  |  2018  |  Anaesthesia and Intensive Care

PROGNOSTIC SIGNIFICANCE OF LOW LEVEL OF BLOOD GLUCOSE IN SEVERE ACUTE KIDNEY INJURY: A SECONDARY ANALYSIS FROM THE RENAL STUDY

Ying Xie, Jin Lin, Martin Gallagher, Rinaldo Bellomo, Xia Wang, Meg Jardine, Amanda Ying Wang

Conference Proceedings  |  2018  |  NEPHROLOGY DIALYSIS TRANSPLANTATION

Which organ dysfunction scores to use in children with infection?

Francis Leclerc, Alain Duhamel, Stephane Leteurtre, Lahn Straney, Rinaldo Bellomo, Graeme MacLaren, David Pilcher, Luregn J Schlapbach

Journal article  |  2018  |  Intensive Care Medicine

The hemodynamic effects of intravenous paracetamol (acetaminophen) vs normal saline in cardiac surgery patients: A single center placebo controlled randomized study

Elizabeth Chiam, Rinaldo Bellomo, Leonid Churilov, Laurence Weinberg

Journal article  |  2018  |  PLOS ONE

Fluids in sepsis

JR Anstey, AM Deane, R Bellomo

Book Chapter  |  2018

Does Fluid Type and Amount Affect Kidney Function in Critical Illness?

Neil J Glassford, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care Clinics

Quantitative relationships among plasma lactate, inorganic phosphorus, albumin, unmeasured anions and the anion gap in lactic acidosis

James Figge, Rinaldo Bellomo, Moritoki Egi

Journal article  |  2018  |  Journal of Critical Care

Erythropoietin Does Not Alter Serum Profiles of Neuronal and Axonal Biomarkers After Traumatic Brain Injury: Findings From the Australian EPO-TBI Clinical Trial

Sarah C Hellewell, Stefania Mondello, Alison Conquest, Gerry Shaw, Irina Madorsky, Jay V Deng, Lorraine Little, Firas Kobeissy, Nicole Bye, Rinaldo Bellomo, David J Cooper, Shirley Vallance, Jasmine Board, Maria C Morganti-Kossmann

Journal article  |  2018  |  Critical Care Medicine

Magnesium supplementation: Pharmacokinetics in cardiac surgery patients with normal renal function

Peter Biesenbach, Johan Martensson, Eduardo Osawa, Glenn Eastwood, Salvatore Cutuli, Jessica Fairley, George Matalanis, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Patient characteristics, incidence, technique, outcomes and early prediction of tracheostomy in the state of Victoria, Australia

Andrew Casamento, Michael Bailey, Ray Robbins, David Pilcher, Stephen Warrillow, Angaj Ghosh, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Critical Care

Preoperative Renal Functional Reserve Predicts Risk of Acute Kidney Injury After Cardiac Operation

Faeq Husain-Syed, Fiorenza Ferrari, Aashish Sharma, Tommaso Hinna Danesi, Percia Bezerra, Salvador Lopez-Giacoman, Sara Samoni, Massimo de Cal, Valentina Corradi, Grazia Maria Virzi, Silvia De Rosa, Maria Jimena Mucino Bermejo, Carla Estremadoyro, Gianluca Villa, Jose J Zaragoza, Carlotta Caprara, Alessandra Brocca, Horst-Walter Birk, Hans-Dieter Walmrath, Werner Seeger, et al.

Journal article  |  2018  |  The Annals of Thoracic Surgery

Are systematic reviews and meta-analyses still useful research? No

Sylvie Chevret, Niall D Ferguson, Rinaldo Bellomo

Journal article  |  2018  |  Intensive Care Medicine

Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX)

Diane M Mackle, Michael J Bailey, Richard W Beasley, Rinaldo Bellomo, Victoria L Bennett, Adam M Deane, Glenn M Eastwood, Simon Finfer, Ross C Freebairn, Edward Litton, Natalie J Linke, Colin J McArthur, Shay P McGuinness, Rakshit Panwar, Paul J Young

Journal article  |  2018  |  Critical Care and Resuscitation

Renal haemodynamics and oxygenation during and after cardiac surgery and cardiopulmonary bypass

RG Evans, YR Lankadeva, AD Cochrane, B Marino, N Iguchi, MZL Zhu, SG Hood, JA Smith, R Bellomo, BS Gardiner, C-J Lee, DW Smith, CN May

Journal article  |  2018  |  Acta Physiologica

Differential effects of isotonic and hypotonic 4% albumin solution on intracranial pressure and renal perfusion and function

Naoya Iguchi, Junko Kosaka, Joseph Bertolini, Clive N May, Yugeesh R Lankadeva, Rinaldo Bellomo

Journal article  |  2018  |  Critical Care and Resuscitation

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock

B Venkatesh, S Finfer, J Cohen, D Rajbhandari, Y Arabi, R Bellomo, L Billot, M Correa, P Glass, M Harward, C Joyce, Q Li, C McArthur, A Perner, A Rhodes, K Thompson, S Webb, J Myburgh

Journal article  |  2018  |  New England Journal of Medicine

Risk factors for unfavourable postoperative outcome in patients with Crohn's disease undergoing right hemicolectomy or ileocaecal resection. An international audit by ESCP and S-ECCO

A El-Hussuna, T Pinkney, O Zmora, M Frasson, A Bhangu, N Battersby, S Chaudhri, D Nepogodiev, B Singh, S Vennix, D Altomare, W Bemelman, P Christensen, A D'Hoore, S Laurberg, D Morton, T Pinkney, M Rubbini, C Vaizey, L Magill, et al.

Journal article  |  2018  |  Colorectal Disease

Erythropoietin to Reduce Mortality in Traumatic Brain Injury A Post-hoc Dose-effect Analysis

Dashiell C Gantner, Michael Bailey, Jeffrey Presneill, Craig J French, Alistair Nichol, Lorraine Little, Rinaldo Bellomo

Journal article  |  2018  |  Annals of Surgery

Hydroxyethyl starch solutions and patient harm

Ian Roberts, Haleema Shakur, Rinaldo Bellomo, Julian Bion, Simon Finfer, Beverley Hunt, John Myburgh, Anders Perner, Konrad Reinhart

Journal article  |  2018  |  The Lancet

Response to the letter by Sion Jo et al

Rinaldo Bellomo, Ida F Ukor

Journal article  |  2018  |  Journal of Critical Care

Nonsurgical Strategies to Reduce Mortality in Patients Undergoing Cardiac Surgery: An Updated Consensus Process

Giovanni Landoni, Vladimir Lomivorotov, Simona Silvietti, Caetanor Nigro Neto, Antonio Pisano, Gabriele Alvaro, Ludmilla Abrahao Hajjar, Gianluca Paternoster, Hynek Riha, Fabrizio Monaco, Andrea Szekely, Rosalba Lembo, Nesrin A Asian, Giovanni Affronti, Valery Likhvantsev, Cristiano Amarelli, Evgeny Fominskiy, Martina Baiardo Redaelli, Alessandro Putzu, Massimo Baiocchi, et al.

Journal article  |  2018  |  Journal of Cardiothoracic and Vascular Anesthesia

Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit

Luregn J Schlapbach, Lahn Straney, Rinaldo Bellomo, Graeme MacLaren, David Pilcher

Journal article  |  2018  |  Intensive Care Medicine

Review article: Sepsis in the emergency department - Part 2: Investigations and monitoring

Amith Shetty, Stephen PJ Macdonald, Gerben Keijzers, Julian M Williams, Benjamin Tang, Bas De Groot, Kelly Thompson, John F Fraser, Simon Finfer, Rinaldo Bellomo, Jonathan Iredell

Journal article  |  2018  |  Emergency Medicine Australasia

Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials

Luca Cabrini, Giovanni Landoni, Martina Baiardo Radaelli, Omar Saleh, Carmine D Votta, Evgeny Fominskiy, Alessandro Putzu, Cezar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi, Alberto Zangrillo

Journal article  |  2018  |  Critical Care

Cause and Timing of Death and Subgroup Differential Effects of Erythropoietin in the EPO-TBI Study

Markus B Skrifvars, Craig French, Michael Bailey, Jeffrey Presneill, Alistair Nichol, Lorraine Little, Jacques Durantea, Olivier Huet, Samir Haddad, Yaseen Arabi, Colin McArthur, D James Cooper, Rinaldo Bellomo

Journal article  |  2018  |  Journal of Neurotrauma

Can Even One Saphenous Vein Graft Influence Late Survival in Coronary Surgery?

D Canty, A Royse, Z Pawanis, R Bellomo, C Reid, J Ou-Young, D Eccleston, A Ajani, C Royse

Conference Proceedings  |  2018

Extra-Renal Indications for Continuous Renal Replacement Therapy

Suvi T Vaara, Rinaldo Bellomo

Book Chapter  |  2018  |  Contributions to Nephrology

Preface

C Ronco, R Bellomo, JA Kellum, G La Manna

Book  |  2018  |  Contributions to Nephrology

Frequency and significance of qSOFA criteria during adult rapid response team reviews: A prospective cohort study

Maurice LeGuen, Yvonne Ballueer, Richard McKay, Glenn Eastwood, Rinaldo Bellomo, Daryl Jones

Journal article  |  2018  |  Resuscitation

40 Years of Continuous Renal Replacement Therapy Preface

Claudio Ronco, Rinaldo Bellomo, John A Kellum, Gaetano La Manna

Book Chapter  |  2018  |  Contributions to Nephrology

Higher versus Lower Continuous Renal Replacement Therapy Intensity in Critically ill Patients with Liver Dysfunction

Zachary O'Brien, Alan Cass, Louise Cole, Simon Finfer, Martin Gallagher, Colin McArthur, Shay McGuiness, John Myburgh, Rinaldo Bellomo, Johan Martensson

Journal article  |  2018  |  Blood Purification

Fluid bolus therapy for the ward treatment of oliguria after major abdominal surgery

MA Kubicki, GM Eastwood, R Bellomo

Journal article  |  2018  |  Anaesthesia and intensive care

Respiratory Failure Patterns in Persistently Critically Ill Patients

EM Viglianti, RD Kramer, MW Sjoding, CL Hodgson, R Bellomo, TJ Iwashyna

Conference Proceedings  |  2018  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic Acute Kidney Injury

Yugeesh R Lankadeva, Junko Kosaka, Roger G Evans, Rinaldo Bellomo, Clive N May

Journal article  |  2018  |  Critical Care Medicine

Associations of fluid amount, type, and balance and acute kidney injury in patients undergoing major surgery

L Weinberg, MHG Li, L Churilov, A Armellini, M Gibney, T Hewitt, CO Tan, R Robbins, D Tremewen, C Christophi, R Bellomo

Journal article  |  2018  |  Anaesthesia and Intensive Care

Angiotensin II for the Treatment of Vasodilatory Shock REPLY

Ashish Khanna, Marlies Ostermann, Rinaldo Bellomo

Journal article  |  2017  |  New England Journal of Medicine

Continuous Renal Replacement Therapy: Modalities and Their Selection

R Bellomo, C Ronco

Book Chapter  |  2017

Critical Care Nephrology: Third Edition

C Ronco, R Bellomo, JA Kellum, Z Ricci

Book  |  2017

Renal Replacement Therapy for Septic Acute Kidney Injury

MJ Maiden, R Bellomo

Book Chapter  |  2017

Blood Glucose Control in Critical Care

J Mårtensson, M Egi, R Bellomo

Book Chapter  |  2017

The Concept of Renal Replacement Therapy Dose and Efficiency

Z Ricci, R Bellomo, JA Kellum, S Romagnoli, C Ronco

Book Chapter  |  2017

Pharmacodynamics of intravenous frusemide bolus in critically ill patients

Luca Cioccari, Rinaldo Bellomo

Journal article  |  2017  |  CRITICAL CARE AND RESUSCITATION

More quality for trials in critically ill patients

Martina Baiardo Redaelli, Luca Cabrini, Giovanni Landoni, Rinaldo Bellomo

Journal article  |  2017  |  Journal of Critical Care

Renal effects of an emergency department chloride-restrictive intravenous fluid strategy in patients admitted to hospital for more than 48 hours

Nor'azim Mohd Yunos, Rinaldo Bellomo, David McD Taylor, Simon Judkins, Fergus Kerr, Harvey Sutcliffe, Colin Hegarty, Michael Bailey

Journal article  |  2017  |  Emergency Medicine Australasia

The effect of low-dose furosemide in critically ill patients with early acute kidney injury: A pilot randomized blinded controlled trial (the SPARK study)

Sean M Bagshaw, RT Noel Gibney, Peter Kruger, Imran Hassan, Finlay A McAlister, Rinaldo Bellomo

Journal article  |  2017  |  Journal of Critical Care

The SPICE III study protocol and analysis plan: a randomised trial of early goal-directed sedation compared with standard care in mechanically ventilated patients

Yahya Shehabi, Andrew B Forbes, Yaseen Arabi, Frances Bass, Rinaldo Bellomo, Suhaini Kadiman, Belinda D Howe, Colin McArthur, Michael C Reade, Ian Seppelt, Jukka Takala, Steve Webb, Matthew P Wise

Journal article  |  2017  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Magnesium status and magnesium therapy in cardiac surgery: A systematic review and meta-analysis focusing on arrhythmia prevention

Jessica L Fairley, Ling Zhang, Neil J Glassford, Rinaldo Bellomo

Journal article  |  2017  |  Journal of Critical Care

lnterobserver agreement for post mortem renal histopathology and diagnosis of acute tubular necrosis in critically ill patients

Neil J Glassford, Alison Skene, Maria B Guardiola, Matthew J Chan, Sean M Bagshaw, Rinaldo Bellomo, Kim Solez

Journal article  |  2017  |  CRITICAL CARE AND RESUSCITATION

Declining mortality in critically ill patients with cirrhosis in Australia and New Zealand between 2000 and 2015

Avik Majumdar, Michael Bailey, William M Kemp, Rinaldo Bellomo, Stuart K Roberts, David Pilcher

Journal article  |  2017  |  Journal of Hepatology

Review article: Sepsis in the emergency department - Part 1: Definitions and outcomes

Stephen PJ Macdonald, Julian M Williams, Amith Shetty, Rinaldo Bellomo, Simon Finfer, Nathan Shapiro, Gerben Keijzers

Journal article  |  2017  |  Emergency Medicine Australasia

The impact of disability in survivors of critical illness (vol 43, pg 992, 2017)

Carol L Hodgson, Andrew A Udy, Michael Bailey, Jonathan Barrett, Rinaldo Bellomo, Tracey Bucknall, Belinda J Gabbe, Alisa M Higgins, Theodore J Iwashyna, Julian Hunt-Smith, Lynne J Murray, Paul S Myles, Jennie Ponsford, David Pilcher, Craig Walker, Meredith Young, DJ Cooper

Journal article  |  2017  |  Intensive Care Medicine

Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase

Paul J Young, Diane M Mackie, Michael J Bailey, Richard W Beasley, Victoria L Bennett, Adam M Deane, Glenn M Eastwood, Simon Finfer, Ross C Freebairn, Edward Litton, Natalie J Linke, Colin J McArthur, Shay P McGuinness, Rakshit Panwar, Rinaldo Bellomo

Journal article  |  2017  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

Interobserver agreement for post mortem renal histopathology and diagnosis of acute tubular necrosis in critically ill patients.

Neil J Glassford, Alison Skene, Maria B Guardiola, Matthew J Chan, Sean M Bagshaw, Rinaldo Bellomo, Kim Solez

Journal article  |  2017  |  Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine

BACKGROUND: The renal histopathology of critically ill patients dying with acute kidney injury (AKI) in intensive care units of hi..

Levosimendan in Cardiac Surgery.

Giovanni Landoni, Vladimir V Lomivorotov, Rinaldo Bellomo

Journal article  |  2017  |  New England Journal of Medicine

Levosimendan in Cardiac Surgery.

Giovanni Landoni, Vladimir V Lomivorotov, Rinaldo Bellomo

Journal article  |  2017  |  N Engl J Med

Age of Red Cells for Transfusion and Outcomes in Critically Ill Adults

D James Cooper, Zoe K McQuilten, Alistair Nichol, Bridget Ady, Cecile Aubron, Michael Bailey, Rinaldo Bellomo, Dashiell Gantner, David O Irving, Kirsi-Maija Kaukonen, Colin McArthur, Lynne Murray, Ville Pettila, Craig French

Journal article  |  2017  |  New England Journal of Medicine

Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass Reply

Giovanni Landoni, Vladimir V Lomivorotov, Rinaldo Bellomo

Journal article  |  2017  |  NEW ENGLAND JOURNAL OF MEDICINE

Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment

Ying Wang, Rinaldo Bellomo

Journal article  |  2017  |  Nature Reviews Nephrology

Vitamin B1 in critically ill patients: needs and challenges

Jake TB Collie, Ronda F Greaves, Oliver AH Jones, Que Lam, Glenn M Eastwood, Rinaldo Bellomo

Journal article  |  2017  |  Clinical Chemistry and Laboratory Medicine (CCLM)

Defining fluid removal in the intensive care unit: A national and international survey of critical care practice.

Michael E O'Connor, Sarah L Jones, Neil J Glassford, Rinaldo Bellomo, John R Prowle

Journal article  |  2017  |  Journal of the Intensive Care Society