Ruth Mackinnon

Detailed molecular cytogenetic characterisation of the myeloid cell line U937 reveals the fate of homologous chromosomes and shows that centromere capture is a feature of genome instability

Ruth N MacKinnon, Joanne Peverall, Lynda J Campbell, Meaghan Wall

Journal article  |  2020  |  Molecular Cytogenetics

BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus-associated T/NK-cell lymphoma

Nenad Sejic, Lindsay C George, Rosemary J Tierney, Catherine Chang, Olga Kondrashova, Ruth N MacKinnon, Ping Lan, Andrew Bell, Guillaume Lessene, Heather M Long, Andreas Strasser, Claire Shannon-Lowe, Gemma L Kelly

Journal article  |  2020  |  Blood Advances

Epstein-Barr virus (EBV)-associated T- and natural killer (NK)-cell malignancies, such as extranodal NK-/T-cell lymphoma (ENKTL), ..

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

Matthew Ku, Ruth N MacKinnon, Meaghan Wall, Nisha Narayan, Carl Walkley, Heung-Chin Cheng, Lynda J Campbell, Louise E Purton, Harshal Nandurkar

Journal article  |  2019  |  Scientific Reports

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

Anuratha Sakthianandeswaren, Marie J Parsons, Dmitri Mouradov, Ruth N MacKinnon, Bruno Catimel, Sheng Liu, Michelle Palmieri, Christopher Love, Robert N Jorissen, Shan Li, Lachlan Whitehead, Tracy L Putoczki, Adele Preaudet, Cary Tsui, Cameron J Nowell, Robyn L Ward, Nicholas J Hawkins, Jayesh Desai, Peter Gibbs, Matthias Ernst, et al.

Journal article  |  2018  |  Cancer Discovery

Analysis of Chromothripsis by Combined FISH and Microarray Analysis

Ruth N MacKinnon

Journal article  |  2018  |  Methods in molecular biology (Clifton, N.J.)

Active centromere and chromosome identification in fixed cell lines

Thian T Beh, Ruth N MacKinnon, Paul Kalitsis

Journal article  |  2016  |  Molecular Cytogenetics

The Dicentric Chromosome dic(20;22) Is a Recurrent Abnormality in Myelodysplastic Syndromes and Is a Product of Telomere Fusion

Ruth N MacKinnon, Hendrika M Duivenvoorden, Lynda J Campbell, Meaghan Wall

Journal article  |  2016  |  Cytogenetic and Genome Research

Src family kinases and their role in hematological malignancies

Matthew Ku, Meaghan Wall, Ruth N MacKinnon, Carl R Walkley, Louise E Purton, Constantine Tam, David Izon, Lynda Campbell, Heung-Chin Cheng, Harshal Nandurkar

Journal article  |  2015  |  Leukemia & Lymphoma

Chromothripsis under the microscope: a cytogenetic perspective of two cases of AML with catastrophic chromosome rearrangement

Ruth N MacKinnon, Lynda J Campbell

Journal article  |  2013  |  Cancer Genetics

Genome organization and the role of centromeres in evolution of the erythroleukaemia cell line HEL.

Ruth N Mackinnon, Meaghan Wall, Adrian Zordan, Srilakshmi Nutalapati, Bruce Mercer, Joanne Peverall, Lynda J Campbell

Journal article  |  2013  |  Evolution Medicine and Public Health

BACKGROUND AND OBJECTIVES: The human erythroleukaemia (HEL) cell line has a highly rearranged genome. We matched whole chromosome ..