Jamie Rossjohn

Letter to the Editor: Growth Hormone Stops Excessive Inflammation After Partial Hepatectomy, Allowing Liver Regeneration and Survival by Induction of H2-Bl/HLA-G REPLY

Andrew J Brooks, Mayumi Ishikawa, Manuel A Fernandez-Rojo, Julian P Vivian, Jamie Rossjohn, Michael J Waters

Journal article  |  2021  |  HEPATOLOGY

We would like to provide information that address the Letter to Editors submitted on 17 July 2020 by Lin and Yan regarding our pub..

The cryo-EM structure of the endocytic receptor DEC-205.

Benjamin S Gully, Hariprasad Venugopal, Alex J Fulcher, Zhihui Fu, Jessica Li, Felix A Deuss, Carmen Llerena, William R Heath, Mireille H Lahoud, Irina Caminschi, Jamie Rossjohn, Richard Berry

Journal article  |  2021  |  J Biol Chem

DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endocytic receptor of dendritic cel..

Growth Hormone Stops Excessive Inflammation After Partial Hepatectomy, Allowing Liver Regeneration and Survival Through Induction of H2-Bl/HLA-G

Mayumi Ishikawa, Andrew J Brooks, Manuel A Fernandez-Rojo, Johan Medina, Yash Chhabra, Shiro Minami, Kathryn A Tunny, Robert G Parton, Julian P Vivian, Jamie Rossjohn, Viral Chikani, Grant A Ramm, Ken KY Ho, Michael J Waters

Journal article  |  2020  |  HEPATOLOGY

BACKGROUND AND AIMS: Growth hormone (GH) is important for liver regeneration after partial hepatectomy (PHx). We investigated this..

Cytomegalovirus replication is associated with enrichment of distinct g 8 T cell subsets following lung transplantation: A novel therapeutic approach?

Sanda Stankovic, Martin S Davey, Evangeline M Shaw, Anouk von Borstel, Yvonne Cristiano, Bronwyn J Levvey, Jamie Rossjohn, Glen P Westall, Gregory I Snell, Andrew G Brooks, Lucy C Sullivan

Journal article  |  2020  |  JOURNAL OF HEART AND LUNG TRANSPLANTATION

BACKGROUND: Anti-viral treatments to control cytomegalovirus (CMV) after lung transplantation (LTx) are associated with toxicity a..

A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response

Roeland Lameris, Adam Shahine, Daniel G Pellicci, Adam P Uldrich, Stephanie Gras, Jerome Le Nours, Richard WJ Groen, Jana Vree, Scott JJ Reddiex, Sergio M Quinones-Parra, Stewart K Richardson, Amy R Howell, Sonja Zweegman, Dale I Godfrey, Tanja D de Gruijl, Jamie Rossjohn, Hans J van der Vliet

Journal article  |  2020  |  NATURE CANCER

Antibody-mediated modulation of major histocompatibility complex (MHC) molecules, or MHC class I-like molecules, could constitute ..

Atypical TRAV1-2(-) T cell receptor recognition of the antigen-presenting molecule MR1

Wael Awad, Erin W Meermeier, Maria L Sandoval-Romero, Jerome Le Nours, Aneta H Worley, Megan D Null, Ligong Liu, James McCluskey, David P Fairlie, David M Lewinsohn, Jamie Rossjohn

Journal article  |  2020  |  JOURNAL OF BIOLOGICAL CHEMISTRY

MR1 presents vitamin B-related metabolites to mucosal associated invariant T (MAIT) cells, which are characterized, in part, by th..

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

Hamish EG McWilliam, Jeffrey YW Mak, Wael Awad, Matthew Zorkau, Sebastian Cruz-Gomez, Hui Jing Lim, Yuting Yan, Sam Wormald, Laura F Dagley, Sidonia BG Eckle, Alexandra J Corbett, Haiyin Liu, Shihan Li, Scott JJ Reddiex, Justine D Mintern, Ligong Liu, James McCluskey, Jamie Rossjohn, David P Fairlie, Jose A Villadangos

Journal article  |  2020  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The antigen-presenting molecule MR1 (MHC class I-related protein 1) presents metabolite antigens derived from microbial vitamin B2..

Overlapping Peptides Elicit Distinct CD8( ) T Cell Responses following Influenza A Virus Infection

Lisa M Assmus, Jing Guan, Ting Wu, Carine Farenc, Xavier YX Sng, Pirooz Zareie, Angela Nguyen, Andrea T Nguyen, David C Tscharke, Paul G Thomas, Jamie Rossjohn, Stephanie Gras, Nathan P Croft, Anthony W Purcell, Nicole L La Gruta

Journal article  |  2020  |  JOURNAL OF IMMUNOLOGY

The presentation of pathogen-derived peptides on MHC class I molecules is essential for the initiation of adaptive CD8+ T cell imm..

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals

Louise C Rowntree, Thi HO Nguyen, Carine Farenc, Hanim Halim, Luca Hensen, Jamie Rossjohn, Tom C Kotsimbos, Anthony W Purcell, Katherine Kedzierska, Stephanie Gras, Nicole A Mifsud

Journal article  |  2020  |  JOURNAL OF IMMUNOLOGY

EBV is one of the most common viruses found in humans and is prototypic of a persistent viral infection characterized by periods o..

Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls

Sara Suliman, Anele Gela, Simon C Mendelsohn, Sarah K Iwany, Kattya Lopez Tamara, Simbarashe Mabwe, Nicole Bilek, Fatoumatta Darboe, Michelle Fisher, Alexandra J Corbett, Lars Kjer-Nielsen, Sidonia BG Eckle, Chuan-Chin Huang, Zibiao Zhang, David M Lewinsohn, James McCluskey, Jamie Rossjohn, Mark Hatherill, Segundo R Leon, Roger Calderon, et al.

Journal article  |  2020  |  JOURNAL OF INFECTIOUS DISEASES

BACKGROUND: In human blood, mucosal-associated invariant T (MAIT) cells are abundant T cells that recognize antigens presented on ..