Vicky Perreau

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse

Jacqueline Heighway, Alicia Sedo, Anjali Garg, Lauren Eldershaw, Victoria Perreau, Geza Berecki, Christopher A Reid, Steven Petrou, Snezana Maljevic

Journal article  |  2022  |  NEUROBIOLOGY OF DISEASE

Genetic variation in voltage-gated sodium (NaV) channels is a significant contributor to neurodevelopmental disorders. NaV channel..

Acetylcholine Muscarinic M-4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents

Leigh C Walker, Alice E Berizzi, Nicola A Chen, Patricia Rueda, Victoria M Perreau, Katherine Huckstep, Jirawoot Srisontiyakul, Piyarat Govitrapong, Xiaojian Jia, Craig W Lindsley, Carrie K Jones, Darren M Riddy, Arthur Christopoulos, Christopher J Langmead, Andrew J Lawrence

Journal article  |  2020  |  BIOLOGICAL PSYCHIATRY

BACKGROUND: Alcohol use disorder (AUD) is a major socioeconomic burden on society, and current pharmacotherapeutic treatment optio..

MUSCARINIC ACETYLCHOLINE RECEPTORS IN ALCOHOL USE DISORDER

LC Walker, AE Berrizi, NA Chen, P Rueda, VM Perreau, K Huckstep, CW Lidsley, CK Jones, DM Riddy, A Christopoulos, CJ Langmead, AJ Lawrence

Conference Proceedings  |  2020  |  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Inflammation in Traumatic Brain Injury: Roles for Toxic A1 Astrocytes and Microglial-Astrocytic Crosstalk

David PQ Clark, Victoria M Perreau, Sandy R Shultz, Rhys D Brady, Enie Lei, Shilpi Dixit, Juliet M Taylor, Philip M Beart, Wah Chin Boon

Journal article  |  2019  |  NEUROCHEMICAL RESEARCH

Traumatic brain injury triggers neuroinflammation that may contribute to progressive neurodegeneration. We investigated patterns o..

Short-Term Environmental Stimulation Spatiotemporally Modulates Specific Serotonin Receptor Gene Expression and Behavioral Pharmacology in a Sexually Dimorphic Manner in Huntington's Disease Transgenic Mice

Michelle S Zajac, Thibault Renoir, Victoria M Perreau, Shanshan Li, Wendy Adams, Maarten van den Buuse, Anthony J Hannan

Journal article  |  2018  |  FRONTIERS IN MOLECULAR NEUROSCIENCE

Huntington's disease (HD) is a neurodegenerative disorder caused by a tandem repeat mutation encoding an expanded polyglutamine tr..

Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety

AK Short, S Yeshurun, R Powell, VM Perreau, A Fox, JH Kim, TY Pang, AJ Hannan

Journal article  |  2017  |  TRANSLATIONAL PSYCHIATRY

There is growing evidence that the preconceptual lifestyle and other environmental exposures of a father can significantly alter t..

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring

AK Short, KA Fennell, VM Perreau, A Fox, MK O'Bryan, JH Kim, TW Bredy, TY Pang, AJ Hannan

Journal article  |  2016  |  TRANSLATIONAL PSYCHIATRY

Recent studies have suggested that physiological and behavioral traits may be transgenerationally inherited through the paternal l..

Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes

He Xu, Victoria M Perreau, Krista A Dent, Ashley I Bush, David I Finkelstein, Paul A Adlard

Journal article  |  2016  |  JOURNAL OF ALZHEIMERS DISEASE

BACKGROUND: There is strong evidence that iron homeostasis is impaired in the aging and Alzheimer's disease (AD) brain and that th..

Microarray profiling to analyze the effect of Snai1 loss in mouse intestinal epithelium

Gary R Hime, Katja Horvay, Thierry Jarde, Franca Casagranda, Victoria M Perreau, Helen E Abud

Journal article  |  2015  |  GENOMICS DATA

Epithelial stem cells from a variety of tissues have been shown to express genes linked to mesenchymal cell states. The Snail fami..

Galanin is an Autocrine Myelin and Oligodendrocyte Trophic Signal Induced by Leukemia Inhibitory Factor

Melissa M Gresle, Helmut Butzkueven, Victoria M Perreau, Anna Jonas, Junhua Xiao, Stefan Thiem, Fiona E Holmes, William Doherty, Pik-Ying Soo, Michele D Binder, Rainer Akkermann, Vilija G Jokubaitis, Holly S Cate, Mark P Marriott, Andrew L Gundlach, David Wynick, Trevor J Kilpatrick

Journal article  |  2015  |  GLIA

In order to further investigate the molecular mechanisms that regulate oligodendrocyte (OC) survival, we utilized microarrays to c..