Fran Maher

Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation

AR White, F Maher, MW Brazier, MF Jobling, J Thyer, LR Stewart, A Thompson, R Gibson, CL Masters, G Multhaup, K Beyreuther, CJ Barrow, SJ Collins, R Cappai

Journal article  |  2003  |  BRAIN RESEARCH

The Alzheimer's disease Abeta peptide can increase the levels of cell-associated amyloid precursor protein (APP) in vitro. To dete..

Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126

LR Stewart, AR White, MF Jobling, BE Needham, F Maher, J Thyer, K Beyreuther, CL Masters, SJ Collins, R Cappai

Journal article  |  2001  |  JOURNAL OF NEUROSCIENCE RESEARCH

Transmissible spongiform encephalopathies are characterised by the transformation of the normal cellular prion protein (PrP(C)) in..