Karen Laurie

New Technologies for Influenza Vaccines

Steven Rockman, Karen L Laurie, Simone Parkes, Adam Wheatley, Ian G Barr

Journal article  |  2020  |  MICROORGANISMS

Vaccine development has been hampered by the long lead times and the high cost required to reach the market. The 2020 pandemic, ca..

Immunogenicity of the inactivated influenza vaccine in children who have undergone autologous stem cell transplant

Anne L Ryan, Ushma D Wadia, Peter Jacoby, Laurence C Cheung, Fiona Kerr, Chris Fraser, Heather Tapp, Louise A Carolan, Karen L Laurie, Ian G Barr, Christopher C Blyth, Nicholas G Gottardo, Peter C Richmond, Rishi S Kotecha

Journal article  |  2020  |  BONE MARROW TRANSPLANTATION

Pandemic Influenza Vaccines: What did We Learn from the 2009 Pandemic and are We Better Prepared Now?

Steven Rockman, Karen Laurie, Ian Barr

Journal article  |  2020  |  VACCINES

In 2009, a novel A(H1N1) influenza virus emerged with rapid human-to-human spread and caused the first pandemic of the 21st centur..

Immunogenicity of the inactivated influenza vaccine in children who have undergone allogeneic haematopoietic stem cell transplant

Anne L Ryan, Ushma D Wadia, Peter Jacoby, Laurence C Cheung, Fiona Kerr, Chris Fraser, Heather Tapp, Francoise Mechinaud, Louise A Carolan, Karen L Laurie, Ian G Barr, Christopher C Blyth, Nicholas G Gottardo, Peter C Richmond, Rishi S Kotecha

Journal article  |  2020  |  BONE MARROW TRANSPLANTATION

Influenza vaccination is recommended for children following allogeneic haematopoietic stem cell transplant (HSCT), however there i..

Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets.

James A Hay, Karen Laurie, Michael White, Steven Riley

Journal article  |  2019  |  PLoS Comput Biol

The strength and breadth of an individual's antibody repertoire is an important predictor of their response to influenza infection..

Influenza A Virus Infection Induces Viral and Cellular Defective Ribosomal Products Encoded by Alternative Reading Frames

Damien J Zanker, Sara Oveissi, David C Tscharke, Mubing Duan, Siyuan Wan, Xiaomu Zhang, Kun Xiao, Nicole A Mifsud, James Gibbs, Lenny Izzard, Daniel Dlugolenski, Pierre Faou, Karen L Laurie, Nathalie Vigneron, Ian G Barr, John Stambas, Benoit J Van den Eynde, Jack R Bennink, Jonathan W Yewdell, Weisan Chen

Journal article  |  2019  |  JOURNAL OF IMMUNOLOGY

The importance of antiviral CD8+ T cell recognition of alternative reading frame (ARF)-derived peptides is uncertain. In this stud..

Measurement of Humoral Immune Competence and the Risk of Sinopulmonary Infection in a Cohort of Kidney Transplant Recipients

C Dendle, RL Stuart, WR Mulley, KR Polkinghorne, PY Gan, J Kanellis, J Ngui, K Laurie, K Thursky, VK Leung, SR Holdsworth

Journal article  |  2018  |  TRANSPLANTATION PROCEEDINGS

PURPOSE: The aim of this study was to determine if measurement of B cell protective immunity was associated with susceptibility to..

Safety, immunogenicity and protection of A(H3N2) live attenuated influenza vaccines containing wild-type nucleoprotein in a ferret model

Daniil A Korenkov, Karen L Laurie, Patrick C Reading, Louise A Carolan, Kok Fei Chan, Irina I Isakova-Sivak, Tatiana A Smolonogina, Kanta Subbarao, Ian G Barr, Julie Villanueva, Svetlana Shcherbik, Tatiana Bousse, Larisa G Rudenko

Journal article  |  2018  |  INFECTION GENETICS AND EVOLUTION

Live attenuated influenza vaccines (LAIVs) are promising tools for the induction of broad protection from influenza due to their a..

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

Kok Fei Chan, Louise A Carolan, Daniil Korenkov, Julian Druce, James McCaw, Patrick C Reading, Ian G Barr, Karen L Laurie

Journal article  |  2018  |  JOURNAL OF INFECTIOUS DISEASES

Epidemiological studies have observed that the seasonal peak incidence of influenza virus infection is sometimes separate from the..

Brugia malayi infection in ferrets - A small mammal model of lymphatic filariasis.

Belinda M Jackson-Thompson, So Young Kim, Shalini Jaiswal, Jessica R Scott, Scott R Jones, C Paul Morris, J Judd Fite, Karen Laurie, Andrew R Hoy, Bernard J Dardzinski, Edward Mitre

Journal article  |  2018  |  PLoS Negl Trop Dis

BACKGROUND: The lack of effective short-course therapies for treatment of the adult stage of filarial worms is a major limitation ..