Karen Laurie

Cell-Based Manufacturing Technology Increases Antigenic Match of Influenza Vaccine and Results in Improved Effectiveness.

Steven Rockman, Karen Laurie, Chi Ong, Sankarasubramanian Rajaram, Ian McGovern, Vy Tran, John Youhanna

Journal article  |  2022  |  Vaccines (Basel)

To ensure that vaccination offers the best protection against an infectious disease, sequence identity between the vaccine and the..

Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation.

Xiaoming Liu, Xiang Li, Ling Chen, Alan Chen-Yu Hsu, Kelly L Asquith, Chi Liu, Karen Laurie, Ian Barr, Paul S Foster, Ming Yang

Journal article  |  2022  |  Front Immunol

Virus-induced asthma exacerbation is a health burden worldwide and lacks effective treatment. To better understand the disease pat..

Enhanced isolation of influenza viruses in qualified cells improves the probability of well-matched vaccines

Heidi Peck, Karen L Laurie, Steve Rockman, Vivian Leung, Hilda Lau, Sally Soppe, Cleve Rynehart, Chantal Baas, Heidi Trusheim, Ian G Barr

Journal article  |  2021  |  NPJ VACCINES

Influenza vaccines are utilised to combat seasonal and pandemic influenza. The key to influenza vaccination currently is the avail..

Influenza lineage extinction during the COVID-19 pandemic?

Marios Koutsakos, Adam K Wheatley, Karen Laurie, Stephen J Kent, Steve Rockman

Journal article  |  2021  |  NATURE REVIEWS MICROBIOLOGY

The SARS-CoV-2 pandemic has seen a notable global reduction in influenza cases of both influenza A and B viruses. In particular, t..

IL-17A is a common and critical driver of impaired lung function and immunopathology induced by influenza virus, rhinovirus and respiratory syncytial virus

Xiaoming Liu, Thi Hiep Nguyen, Leon Sokulsky, Xiang Li, Keilah Garcia Netto, Alan Chen-Yu Hsu, Chi Liu, Karen Laurie, Ian Barr, Hock Tay, Fiona Eyers, Paul S Foster, Ming Yang

Journal article  |  2021  |  RESPIROLOGY

BACKGROUND AND OBJECTIVE: Influenza virus (FLU), rhinovirus (RV) and respiratory syncytial virus (RSV) are the most common acute r..

Impact of prior vaccination on antibody response and influenza-like illness among Australian healthcare workers after influenza vaccination in 2016

Vivian KY Leung, Annette Fox, Louise A Carolan, Malet Aban, Karen L Laurie, Julian Druce, Yi-Mo Deng, Monica A Slavin, Caroline Marshall, Sheena G Sullivan

Journal article  |  2021  |  VACCINE

BACKGROUND: Epidemiological studies suggest that influenza vaccine effectiveness decreases with repeated administration. We examin..

Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients

Thi HO Nguyen, Marios Koutsakos, Carolien E van de Sandt, Jeremy Chase Crawford, Liyen Loh, Sneha Sant, Ludivine Grzelak, Emma K Allen, Tim Brahm, E Bridie Clemens, Maria Auladell, Luca Hensen, Zhongfang Wang, Simone Nussing, Xiaoxiao Jia, Patrick Gunther, Adam K Wheatley, Stephen J Kent, Malet Aban, Yi-Mo Deng, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

How innate and adaptive immune responses work in concert to resolve influenza disease is yet to be fully investigated in one singl..

Which influenza viruses will emerge following the SARS-CoV-2 pandemic?

Karen L Laurie, Steve Rockman

Journal article  |  2021  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

The world has experienced five pandemics in just over one hundred years, four due to influenza and one due to coronavirus (SARS-Co..

New Technologies for Influenza Vaccines

Steven Rockman, Karen L Laurie, Simone Parkes, Adam Wheatley, Ian G Barr

Journal article  |  2020  |  MICROORGANISMS

Vaccine development has been hampered by the long lead times and the high cost required to reach the market. The 2020 pandemic, ca..

Immunogenicity of the inactivated influenza vaccine in children who have undergone autologous stem cell transplant

Anne L Ryan, Ushma D Wadia, Peter Jacoby, Laurence C Cheung, Fiona Kerr, Chris Fraser, Heather Tapp, Louise A Carolan, Karen L Laurie, Ian G Barr, Christopher C Blyth, Nicholas G Gottardo, Peter C Richmond, Rishi S Kotecha

Journal article  |  2020  |  BONE MARROW TRANSPLANTATION