Anton Cozijnsen

A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver T-RM Cell-Mediated Immunity against Malaria in Mice

Ana Maria Valencia-Hernandez, Wei Yi Ng, Nazanin Ghazanfari, Sonia Ghilas, Maria N de Menezes, Lauren E Holz, Cheng Huang, Kieran English, Myo Naung, Peck Szee Tan, Kirsteen M Tullett, Thiago M Steiner, Matthias H Enders, Lynette Beattie, Yu Cheng Chua, Claerwen M Jones, Anton Cozijnsen, Vanessa Mollard, Yeping Cai, David G Bowen, et al.

Journal article  |  2020  |  Cell Host & Microbe

Liver-resident memory CD8+ T (TRM) cells remain in and constantly patrol the liver to elicit rapid immunity upon antigen encounter..

Glycolipid-peptide vaccination induces liver-resident memory CD8( ) T cells that protect against rodent malaria

Lauren E Holz, Yu Cheng Chua, Maria N de Menezes, Regan J Anderson, Sarah L Draper, Benjamin J Compton, Susanna TS Chan, Juby Mathew, Jasmine Li, Lukasz Kedzierski, Zhongfang Wang, Lynette Beattie, Matthias H Enders, Sonia Ghilas, Rose May, Thiago M Steiner, Joshua Lange, Daniel Fernandez-Ruiz, Ana Maria Valencia-Hernandez, Taryn L Osmond, et al.

Journal article  |  2020  |  Science Immunology

Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vacc..

Glycolipid-peptide vaccination induces liver-resident memory CD8 T cells that protect against malaria

Lauren Holz, Yu Cheng Chua, Regan Anderson, Sarah Draper, Benjamin Compton, Susanna Chan, Juby Mathew, Maria de Menezes, Anton Cozijnsen, Vanessa Mollard, Geoffrey McFadden, Gavin Painter, William R Heath

Conference Proceedings  |  2020  |  JOURNAL OF IMMUNOLOGY

Alternative splicing is required for stage differentiation in malaria parasites

Lee M Yeoh, Christopher D Goodman, Vanessa Mollard, Emma McHugh, V Vern Lee, Angelika Sturm, Anton Cozijnsen, Geoffrey I McFadden, Stuart A Ralph

Journal article  |  2019  |  Genome Biology

CD8( ) T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

Lauren E Holz, Julia E Prier, David Freestone, Thiago M Steiner, Kieran English, Darryl N Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M Davey, Dale Godfrey, Katsuyuki Yui, Laura K Mackay, Mireille H Lahoud, Irina Caminschi, Geoffrey McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R Heath

Journal article  |  2018  |  Cell Reports

Development of a Novel CD4( ) TCR Transgenic Line That Reveals a Dominant Role for CD8( ) Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari, Claerwen M Jones, Wei Yi Ng, Gayle M Davey, Dorothee Berthold, Lauren Holz, Yu Kato, Matthias H Enders, Ganchimeg Bayarsaikhan, Sanne H Hendriks, Lianne IM Lansink, Jessica A Engel, Megan SF Soon, Kylie R James, Anton Cozijnsen, Vanessa Mollard, Alessandro D Uboldi, Christopher J Tonkin, et al.

Journal article  |  2017  |  The Journal of Immunology

LIVER-RESIDENT MEMORY T CELLS CAN BE HARNESSED FOR UNPRECEDENTED PROTECTION AGAINST MALARIA

Daniel Fernandez-Ruiz, Wei Yi Ng, Lauren Holz, Anton Cozijnsen, Vanessa Mollard, Roghieh Skandari, Jonathan H Manton, Szun Szun Tay, David G Bowen, Friedrich Koch-Nolte, Bjorn Rissiek, Francis R Carbone, Brendan S Crabb, Scott N Mueller, Patrick Bertolino, Geoffrey I McFadden, Irina Caminschi, William R Heath

Conference Proceedings  |  2017  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Liver-Resident Memory CD8( ) T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

Daniel Fernandez-Ruiz, Wei Yi Ng, Lauren E Holz, Joel Z Ma, Ali Zaid, Yik Chun Wong, Lei Shong Lau, Vanessa Mollard, Anton Cozijnsen, Nicholas Collins, Jessica Li, Gayle M Davey, Yu Kato, Sapna Devi, Roghieh Skandari, Michael Pauley, Jonathan H Manton, Dale I Godfrey, Asolina Braun, Szun Szun Tay, et al.

Journal article  |  2016  |  Immunity

Liver resident memory T cells express CXCR6 and patrol in the sinusoids

L Holz, D Fernandez-Ruiz, A Zaid, WY Ng, YC Wong, V Mollard, A Cozijnsen, G Davey, D Bowen, SS Tay, M Lahoud, P Bertolino, S Mueller, G McFadden, I Caminschi, W Heath

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Using a "prime-and-trap" vaccine strategy to generate liver TRM and protect mice form malaria liver-stage infection

WY Ng, D Fernandez-Ruiz, J Ma, A Zaid, YC Wong, LS Lau, V Mollard, A Cozijnsen, N Collins, J Li, GM Davey, L Holz, SS Tay, PS Tan, DG Bowen, F Koch-Nolte, R Bjoern, FR Carbone, BS Crabb, M Lahoud, et al.

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY