Dhana Gorasia

Structural Characterization of the Type IX Secretion System in Porphyromonas gingivalis.

Dhana G Gorasia, Eric Hanssen, Paul D Veith, Eric C Reynolds

Journal article  |  2021  |  Methods in molecular biology (Clifton, N.J.)

The type IX secretion system (T9SS) is the most recently discovered secretion system in the gram-negative bacteria and is specific..

Quantitative proteomic analysis of the type IX secretion system mutants in Porphyromonas gingivalis

Dhana G Gorasia, Michelle D Glew, Paul D Veith, Eric C Reynolds

Journal article  |  2020  |  Molecular Oral Microbiology

Porphyromonas gingivalis is an anaerobic, Gram-negative human oral pathogen highly associated with chronic periodontitis. P. gingi..

Localization of Outer Membrane Proteins in Treponema denticola by Quantitative Proteome Analyses of Outer Membrane Vesicles and Cellular Fractions

Paul D Veith, Michelle D Glew, Dhana G Gorasia, Dina Chen, Neil M O'Brien-Simpson, Eric C Reynolds

Journal article  |  2019  |  Journal of Proteome Research

Porphyromonas gingivalis Gingipains Display Transpeptidation Activity

Lianyi Zhang, Paul D Veith, N Laila Huq, Yu-Yen Chen, Christine A Seers, Keith J Cross, Dhana G Gorasia, Eric C Reynolds

Journal article  |  2018  |  Journal of Proteome Research

Type IX secretion: the generation of bacterial cell surface coatings involved in virulence, gliding motility and the degradation of complex biopolymers

Paul D Veith, Michelle D Glew, Dhana G Gorasia, Eric C Reynolds

Journal article  |  2017  |  MOLECULAR MICROBIOLOGY

PorV is an Outer Membrane Shuttle Protein for the Type IX Secretion System

Michelle D Glew, Paul D Veith, Dina Chen, Dhana G Gorasia, Ben Peng, Eric C Reynolds

Journal article  |  2017  |  SCIENTIFIC REPORTS

Structural Insights into the PorK and PorN Components of the Porphyromonas gingivalis Type IX Secretion System

Dhana G Gorasia, Paul D Veith, Eric G Hanssen, Michelle D Glew, Keiko Sato, Hideharu Yukitake, Koji Nakayama, Eric C Reynolds

Journal article  |  2016  |  PLOS PATHOGENS

A prominent role of PDIA6 in processing of misfolded proinsulin

Dhana G Gorasia, Nadine L Dudek, Helena Safavi-Hemami, Rochelle Ayala Perez, Ralf B Schittenhelm, Philippa M Saunders, Sheena Wee, Jon E Mangum, Michael J Hubbard, Anthony W Purcell

Journal article  |  2016  |  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism

Dhana G Gorasia, Paul D Veith, Dina Chen, Christine A Seers, Helen A Mitchell, Yu-Yen Chen, Michelle D Glew, Stuart G Dashper, Eric C Reynolds

Journal article  |  2015  |  PLOS PATHOGENS

Pancreatic Beta Cells Are Highly Susceptible to Oxidative and ER Stresses during the Development of Diabetes

Dhana G Gorasia, Nadine L Dudek, Paul D Veith, Renu Shankar, Helena Safavi-Hemami, Nicholas A Williamson, Eric C Reynolds, Michael J Hubbard, Anthony W Purcell

Journal article  |  2015  |  Journal of Proteome Research

Porphyromonas gingivalis Outer Membrane Vesicles Exclusively Contain Outer Membrane and Periplasmic Proteins and Carry a Cargo Enriched with Virulence Factors

Paul D Veith, Yu-Yen Chen, Dhana G Gorasia, Dina Chen, Michelle D Glew, Neil M O'Brien-Simpson, Jessica D Cecil, James A Holden, Eric C Reynolds

Journal article  |  2014  |  Journal of Proteome Research

Combined Proteomic and Transcriptomic Interrogation of the Venom Gland of Conus geographus Uncovers Novel Components and Functional Compartmentalization*

Helena Safavi-Hemami, Hao Hu, Dhana G Gorasia, Pradip K Bandyopadhyay, Paul D Veith, Neil D Young, Eric C Reynolds, Mark Yandell, Baldomero M Olivera, Anthony W Purcell

Journal article  |  2014  |  Molecular and Cellular Proteomics

Protein Substrates of a Novel Secretion System Are Numerous in the Bacteroidetes Phylum and Have in Common a Cleavable C-Terminal Secretion Signal, Extensive Post-Translational Modification, and Cell-Surface Attachment

Paul D Veith, Nor A Nor Muhammad, Stuart G Dashper, Vladimir A Likic, Dhana G Gorasia, Dina Chen, Samantha J Byrne, Deanne V Catmull, Eric C Reynolds

Journal article  |  2013  |  JOURNAL OF PROTEOME RESEARCH

Constitutive and Inflammatory Immunopeptidome of Pancreatic beta-Cells

Nadine L Dudek, Chor Teck Tan, Dhana G Gorasia, Nathan P Croft, Patricia T Illing, Anthony W Purcell

Journal article  |  2012  |  Diabetes

Modulation of Conotoxin Structure and Function Is Achieved through a Multienzyme Complex in the Venom Glands of Cone Snails

Helena Safavi-Hemami, Dhana G Gorasia, Andrew M Steiner, Nicholas A Williamson, John A Karas, Joanna Gajewiak, Baldomero M Olivera, Grzegorz Bulaj, Anthony W Purcell

Journal article  |  2012  |  JOURNAL OF BIOLOGICAL CHEMISTRY

PG0026 Is the C-terminal Signal Peptidase of a Novel Secretion System of Porphyromonas gingivalis

Michelle D Glew, Paul D Veith, Benjamin Peng, Yu-Yen Chen, Dhana G Gorasia, Qiaohui Yang, Nada Slakeski, Dina Chen, Caroline Moore, Simon Crawford, Eric C Reynolds

Journal article  |  2012  |  Journal of Biological Chemistry

Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands

Katherine E Scull, Nadine L Dudek, Alexandra J Corbett, H Ramarathinam, Dhana G Gorasia, Nicholas A Williamson, Anthony W Purcell

Journal article  |  2012  |  Molecular Immunology

Quantification of GFAP Expression in Two EAE Variants Reveals Contrasting Astrocytic Reactivity

CS D'Souza, H Pham, J Doerrbecker, AA Ramp, DG Gorasia, AW Purcell, MM Ayers, JM Orian

Conference Proceedings  |  2012  |  MULTIPLE SCLEROSIS JOURNAL

Specialisation of the Venom Gland Proteome in Predatory Cone Snails Reveals Functional Diversification of the Conotoxin Biosynthetic Pathway

Helena Safavi-Hemami, William A Siero, Dhana G Gorasia, Neil D Young, David MacMillan, Nicholas A Williamson, Anthony W Purcell

Journal article  |  2011  |  Journal of Proteome Research