Jason Ivanusic

Changes to the activity and sensitivity of nerves innervating subchondral bone contribute to pain in late-stage osteoarthritis

Michael Morgan, Jenny Thai, Vida Nazemian, Richard Song, Jason J Ivanusic

Journal article  |  2022  |  PAIN

Although it is clear that osteoarthritis (OA) pain involves activation and/or sensitization of nociceptors that innervate knee joi..

Mini review: The role of sensory innervation to subchondral bone in osteoarthritis pain.

Michael Morgan, Vida Nazemian, Kate Harrington, Jason J Ivanusic

Journal article  |  2022  |  Front Endocrinol (Lausanne)

Osteoarthritis pain is often thought of as a pain driven by nerves that innervate the soft tissues of the joint, but there is emer..

Suprainguinal fascia iliaca block: does it block the obturator nerve?

Thomas Fichtner Bendtsen, Erik Morre Pedersen, Bernhard Moriggl, Peter Hebbard, Jason Ivanusic, Jens Borglum, Thomas Dahl Nielsen, Philip Peng

Journal article  |  2021  |  REGIONAL ANESTHESIA AND PAIN MEDICINE

Anatomical considerations for obturator nerve block with fascia iliaca compartment block

Thomas Fichtner Bendtsen, Erik Morre Pedersen, Bernhard Moriggl, Peter Hebbard, Jason Ivanusic, Jens Borglum, Thomas Dahl Nielsen, Philip Peng

Journal article  |  2021  |  REGIONAL ANESTHESIA AND PAIN MEDICINE

This report reviews the topographical and functional anatomy relevant for assessing whether or not the obturator nerve (ON) can be..

Piezo2 Knockdown Inhibits Noxious Mechanical Stimulation and NGF-Induced Sensitization in A-Delta Bone Afferent Neurons

Sara Nencini, Michael Morgan, Jenny Thai, Andrew II Jobling, Stuart B Mazzone, Jason J Ivanusic

Journal article  |  2021  |  FRONTIERS IN PHYSIOLOGY

Piezo2 is a mechanically gated ion-channel that has a well-defined role in innocuous mechanical sensitivity, but recently has also..

Distribution of Corneal TRPV1 and Its Association With Immune Cells During Homeostasis and Injury

Haihan Jiao, Jason J Ivanusic, Paul G McMenamin, Holly R Chinnery

Journal article  |  2021  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

PURPOSE: Given the role of corneal sensory nerves during epithelial wound repair, we sought to examine the relationship between im..

In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia

Serena Viventi, Stefano Frausin, Sara E Howden, Shiang Y Lim, Rocio K Finol-Urdaneta, Jeffrey R McArthur, Kwaku Dad Abu-Bonsrah, Wayne Ng, Jason Ivanusic, Lachlan Thompson, Mirella Dottori

Journal article  |  2021  |  STEM CELLS TRANSLATIONAL MEDICINE

Friedreich ataxia (FRDA) is an autosomal recessive disease characterized by degeneration of dorsal root ganglia (DRG) sensory neur..

ASIC3 inhibition modulates inflammation-induced changes in the activity and sensitivity of A delta and C fiber sensory neurons that innervate bone

Michael Morgan, Jenny Thai, Phu Trinh, Mohamed Habib, Kelly N Effendi, Jason J Ivanusic

Journal article  |  2020  |  MOLECULAR PAIN

The Acid Sensing Ion Channel 3 (ASIC3) is a non-selective cation channel that is activated by acidification, and is known to have ..

Identifying spinal afferent (sensory) nerve endings that innervate the marrow cavity and periosteum using anterograde tracing

Jenny Thai, Melinda Kyloh, Lee Travis, Nick J Spencer, Jason J Ivanusic

Journal article  |  2020  |  JOURNAL OF COMPARATIVE NEUROLOGY

While sensory and sympathetic neurons are known to innervate bone, previous studies have found it difficult to unequivocally ident..

Partial deletion of p75(NTR)in large-diameter DRG neurons exerts no influence upon the survival of peripheral sensory neuronsin vivo

Zuoheng Qin, David G Gonsalvez, Rhiannon J Wood, Fatemeh Daemi, Sangwon Yoo, Jason J Ivanusic, Elizabeth J Coulson, Simon S Murray, Junhua Xiao

Journal article  |  2020  |  JOURNAL OF NEUROSCIENCE RESEARCH

The p75 neurotrophin receptor (p75NTR ) is required for maintaining peripheral sensory neuron survival and function; however, the ..