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FEATURED Journal article
Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy.Read more
Ken Snibson's selected work
A Large Trial To Evaluate The Efficacy And Safety Of A Bioactive Molecule In A Sheep Mode..
The potential use of L-sulforaphane for the treatment of chronic inflammatory diseases: A ..
Using A Sheep Model Of Pulmonary Fibrosis To Test The Efficacy Of Bioactive Compounds
Displaying the 7 most recent projects by Ken Snibson.
Displaying the 61 most recent scholarly works by Ken Snibson.
Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy.
Nadia Mazarakis, Jitraporn Vongsvivut, Keith R Bambery, Katherine Ververis, Mark J Tobin, Simon G Royce, Chrishan S Samuel, Kenneth J Snibson, Paul V Licciardi, Tom C Karagiannis
Journal article | 2020 | Scientific Reports
The ovalbumin-induced (OVA) chronic allergic airways murine model is a well-established model for investigating pre-clinical thera..
The potential use of L-sulforaphane for the treatment of chronic inflammatory diseases: A review of the clinical evidence
Nadia Mazarakis, Kenneth Snibson, Paul V Licciardi, Tom C Karagiannis
Journal article | 2020 | Clinical Nutrition
According to the World Health Organisation, 70% of all deaths globally can be attributed to chronic inflammatory diseases such as ..
The efficacy of pirfenidone in a sheep model of pulmonary fibrosis.
Sasika NV Dewage, Louise Organ, Emmanuel Koumoundouros, Habtamu B Derseh, Kopiyawaththage UE Perera, Chrishan S Samuel, Andrew W Stent, Ken J Snibson
Journal article | 2020 | Experimental Lung Research
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disease with unknown cause. While the drugs nintedanib ..
K(Ca)3.1 channel blockade attenuates microvascular remodelling in a large animal model of bleomycin-induced pulmonary fibrosis
Habtamu B Derseh, Sasika N Vithana Dewage, Kopiyawaththage UE Perera, Charles N Pagel, Emmanuel Koumoundouros, Louise Organ, Ken J Snibson
Journal article | 2019 | Scientific Reports
In vivo blockade of KCa3.1 ion channel alleviates ER stress in type II alveolar epithelial cells and macrophages in pulmonary fibrosis
K Udari Eshani Perera, Sasika Nimanthi Vithana Dewage, Habtamu B Derseh, Paul John Benham, Andrew Stent, Louise Organ, Ken Snibson
Conference Proceedings | 2019 | Idiopathic interstitial pneumonias
Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling
Junfei Wang, Alen Faiz, Qi Ge, Cornelis J Vermeulen, Joanne Van der Velden, Kenneth J Snibson, Rob van de Velde, Sonia Sawant, Dikaia Xenaki, Brian Oliver, Wim Timens, Nick ten Hacken, Maarten van den Berge, Alan James, John G Elliot, Liang Dong, Janette K Burgess, Anthony W Ashton
Journal article | 2018 | Journal of Cellular and Molecular Medicine
Unique Mechanisms of Connective Tissue Growth Factor Regulation in Airway Smooth Muscle in Asthma: Relationship with Airway Remodelling
JK Burgess, J Wang, A Faiz, Q Ge, CJ Vermeulen, K Snibson, BGG Oliver, W Timens, NH Hacken, M Van den Berge, AL James, J Elliot, L Dong, AW Ashton
Conference Proceedings | 2018 | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Synchrotron-Fourier transform infrared maps of ovalbumin-induced murine chronic allergic airways disease: Correlation with conventional histology.
Nadia Mazarakis, Jitraporn Vongsvivut, Keith R Bambery, Kenneth J Snibson, Simon G Royce, Tom C Karagiannis
Journal article | 2017 | Hellenic journal of nuclear medicine
Asthma is a chronic respiratory disease characterised by airway inflammation, remodeling and hyperresponsiveness. The ability to r..
Inhibition of the K(Ca)3.1 Channel Alleviates Established Pulmonary Fibrosis in a Large Animal Model
Louise Organ, Barbara Bacci, Emmanuel Koumoundouros, Wayne G Kimpton, Chrishan S Samuel, Cameron J Nowell, Peter Bradding, Katy M Roach, Glen Westall, Jade Jaffar, Ken J Snibson
Journal article | 2017 | American Journal of Respiratory Cell and Molecular Biology
The Effects of Tumstatin on Vascularity, Airway Inflammation and Lung Function in an Experimental Sheep Model of Chronic Asthma
Joanne Van der Velden, Louise M Harkness, Donna M Barker, Garry J Barcham, Cathryn L Ugalde, Emmanuel Koumoundouros, Heidi Bao, Louise A Organ, Ana Tokanovic, Janette K Burgess, Kenneth J Snibson
Journal article | 2016 | Scientific Reports
Nebulized perflubron and carbon dioxide rapidly dilate constricted airways in an ovine model of allergic asthma
Tamer Y El Mays, Parichita Choudhury, Richard Leigh, Emmanuel Koumoundouros, Joanne Van der Velden, Grishma Shrestha, Cora A Pieron, John H Dennis, Francis HY Green, Ken J Snibson
Journal article | 2014 | Respiratory Research
Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer
Katrin Friedbichler, Madeleine Themanns, Kristina M Mueller, Michaela Schlederer, Jan-Wilhelm Kornfeld, Luigi M Terracciano, Andrey V Kozlov, Susanne Haindl, Lukas Kenner, Thomas Kolbe, Mathias Mueller, Kenneth J Snibson, Markus H Heim, Richard Moriggl
Journal article | 2012 | Hepatology
Combined mucosal and systemic immunity following pulmonary delivery of ISCOMATRIX (TM) adjuvanted recombinant antigens
Ana Vujanic, Janet LK Wee, Kenneth J Snibson, Stirling Edwards, Martin Pearse, Charles Quinn, Margaret Moloney, Shirley Taylor, Jean-Pierre Y Scheerlinck, Philip Sutton
Journal article | 2010 | Vaccine
Measurement and impact of remodeling in the lung: airway neovascularization in asthma.
Robert J Bischof, Jane E Bourke, Stuart J Hirst, Els NT Meeusen, Kenneth J Snibson, Joanne Van Der Velden
Journal article | 2009 | Proceedings of the American Thoracic Society
Expansion of the airway wall vascular compartment has recently been established as a feature of asthma involving both enlargement ..
Oesophageal techniques for deriving the lung dynamics of quietly breathing sheep
E Koumoundouros, K Snibson, IMY Mareels
Conference Proceedings | 2008 | Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: 'Personalized Healthcare through Technology'
Claims of current inhaled corticosteroid patents for treating asthma.
Shari Lofthouse, Ken Snibson
Journal article | 2007 | Recent Patents on Inflammation & Allergy Drug Discovery
The advent and evolution of corticosteroid treatment strategies over the preceding decades means that asthma is now at least contr..
Ultrastructural localization and gradient of activity of alkaline phosphatase activity during rodent odontogenesis.
HJ Orams, KJ Snibson
Journal article | 1982 | Calcified Tissue International
The ultrastructural localization and gradient of activity of alkaline phosphatase were studied with respect to cell differentiatio..