Wayne Kimpton

Characterisation of ovine lymphatic vessels in fresh specimens

Hung-Hsun Yen, Christina Murray, Elizabeth Washington, Wayne Kimpton, Helen Davies

Journal article  |  2019  |  PLoS One

Abstract Background and aim The development and use of experimental models using lymphatic cannulation techniques have been hampe..

Changes in duodenal CD163-positive cells in dogs with chronic enteropathy after successful treatment

Julien RS Dandrieux, Lina Maria Martinez Lopez, Andrew Stent, Albert Jergens, Karin Allenspach, Cameron J Nowell, Simon M Firestone, Wayne Kimpton, Caroline S Mansfield

Journal article  |  2018  |  INNATE IMMUNITY

Chronic enteropathy (CE) in dogs is characterized retrospectively per treatment response as food-responsive enteropathy (FRE), ant..

Lymphatic cannulation models in sheep: Recent advances for immunological and biomedical research

Elizabeth A Washington, Stuart R Barber, Christina M Murray, Helen MS Davies, Wayne G Kimpton, Hung-Hsun Yen

Journal article  |  2018  |  Journal of Immunological Methods

Lymphatic cannulation models are useful tools for studying the immunobiology of the lymphatic system and the immunopathology of sp..

Inhibition of the K(Ca)3.1 Channel Alleviates Established Pulmonary Fibrosis in a Large Animal Model

Louise Organ, Barbara Bacci, Emmanuel Koumoundouros, Wayne G Kimpton, Chrishan S Samuel, Cameron J Nowell, Peter Bradding, Katy M Roach, Glen Westall, Jade Jaffar, Ken J Snibson

Journal article  |  2017  |  American Journal of Respiratory Cell and Molecular Biology

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease of increasing prevalence marked by poor prognosis and limite..

Immunoselected STRO-3( ) mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis

Anwar Abdalmula, Laura M Dooley, Claire Kaufman, Elizabeth A Washington, Jacqueline V House, Barbara A Blacklaws, Peter Ghosh, Silviu Itescu, Simon R Bailey, Wayne G Kimpton

Journal article  |  2017  |  STEM CELL RESEARCH & THERAPY

BACKGROUND: The purpose of this study was to investigate the therapeutic efficacy of intravenously administered immunoselected STR..

Development of an ovine efferent mammary lymphatic cannulation model with minimal tissue damage

Hung-Hsun Yen, Elizabeth Washington, Wayne Kimpton, Evan Hallein, Joanne Allen, Silk Yu Lin, Stuart Barber

Journal article  |  2016  |  BMC Veterinary Research

BACKGROUND: Two mammary lymphatic cannulation models in sheep have been described with minimal use in the past 50 years. The purpo..

KCA3.1 ION CHANNEL-BLOCKADE ATTENUATES ESTABLISHED PULMONARY FIBROSIS IN A SEGMENTAL BLEOMYCIN CHALLENGE MODEL IN SHEEP

L Organ, E Koumoundouros, B Bacci, C Samuel, W Kimpton, K Snibson

Conference Proceedings  |  2016  |  RESPIROLOGY

Structural and functional correlations in a large animal model of bleomycin-induced pulmonary fibrosis

Louise Organ, Barbara Bacci, Emmanuel Koumoundouros, Garry Barcham, Marjorie Milne, Wayne Kimpton, Chrishan Samuel, Ken Snibson

Journal article  |  2015  |  BMC Pulmonary Medicine

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a severe and progressive respiratory disease with poor prognosis. Despite the p..

Lymphatic System

Elizabeth A Washington, Thilini AN Mahakapuge, Jean‐Pierre Y Scheerlinck, Wayne G Kimpton

Scholarly edition  |  2015

Effect of Mesenchymal Precursor Cells on the Systemic Inflammatory Response and Endothelial Dysfunction in an Ovine Model of Collagen-Induced Arthritis

Laura M Dooley, Anwar Abdalmula, Elizabeth A Washington, Claire Kaufman, Elizabeth M Tudor, Peter Ghosh, Silviu Itescu, Wayne G Kimpton, Simon R Bailey

Journal article  |  2015  |  PLOS ONE

BACKGROUND AND AIM: Mesenchymal precursor cells (MPC) are reported to possess immunomodulatory properties that may prove beneficia..