Marshall Lightowlers

Protection against cystic echinococcosis in sheep using an Escherichia coli-expressed recombinant antigen (EG95) as a bacterin

Charles G Gauci, David J Jenkins, Marshall W Lightowlers

Journal article  |  2022  |  PARASITOLOGY

The EG95 recombinant vaccine is protective against cystic echinococcus in animal intermediate hosts. Preparation of the existing, ..

Chromosome-scale Echinococcus granulosus (genotype G1) genome reveals the Eg95 gene family and conservation of the EG95-vaccine molecule

Pasi K Korhonen, Liina Kinkar, Neil D Young, Huimin Cai, Marshall W Lightowlers, Charles Gauci, Abdul Jabbar, Bill CH Chang, Tao Wang, Andreas Hofmann, Anson Koehler, Junhua Li, Jiandong Li, Daxi Wang, Jiefang Yin, Huanming Yang, David J Jenkins, Urmas Saarma, Teivi Laurimae, Mohammad Rostami-Nejad, et al.

Journal article  |  2022  |  COMMUNICATIONS BIOLOGY

Cystic echinococcosis is a socioeconomically important parasitic disease caused by the larval stage of the canid tapeworm Echinoco..

Advances in the treatment, diagnosis, control and scientific understanding of taeniid cestode parasite infections over the past 50 years

Marshall W Lightowlers, Robin B Gasser, Andrew Hemphill, Thomas Romig, Francesca Tamarozzi, Peter Deplazes, Paul R Torgerson, Hector H Garcia, Peter Kern

Journal article  |  2021  |  International Journal for Parasitology

In the past 50 years, enormous progress has been made in the diagnosis, treatment and control of taeniid cestode infections/diseas..

Immunodiagnostic usefulness of monoclonal antibodies specific to conformational epitopes of Taenia solium oncosphere protein TSOL18

Emmanuel Assana, Andre Pagnah Zoli, Charles G Gauci, Marshall W Lightowlers, Pierre Dorny

Journal article  |  2021  |  JOURNAL OF IMMUNOLOGICAL METHODS

Taenia solium oncosphere protein TSOL18 is the host-protective antigen against porcine cysticercosis. Little attention has been gi..

Combined use of two separate but protective vaccine antigens provides protection against Taenia ovis infection in lambs in the presence of protective maternal antibody

GBL Harrison, DD Heath, CM Robinson, SB Lawrence, RP Dempster, CG Gauci, MW Lightowlers, MD Rickard

Journal article  |  2021  |  VACCINE

Three recombinant Taenia ovis antigens (To45, To16, To18) each induce protective immunity in lambs or ewes against infection with ..

Control trial of porcine cysticercosis in Uganda using a combination of the TSOL18 vaccination and oxfendazole

Zachary Nsadha, Chris Rutebarika, Chrisostom Ayebazibwe, Bukenya Aloys, M Mwanja, E Jane Poole, Elizabeth Chesang, Angela Colston, Meritxell Donadeu, Marshall W Lightowlers

Journal article  |  2021  |  INFECTIOUS DISEASES OF POVERTY

BACKGROUND: Neurocysticercosis caused by Taenia solium when the parasite lodges in the central nervous system, is an important cau..

Control of cystic echinococcosis in the Middle Atlas, Morocco: Field evaluation of the EG95 vaccine in sheep and cesticide treatment in dogs

Fatimaezzahra Amarir, Abdelkbir Rhalem, Abderrahim Sadak, Marianne Raes, Mohamed Oukessou, Aouatif Saadi, Mohammed Bouslikhane, Charles G Gauci, Marshall W Lightowlers, Nathalie Kirschvink, Tanguy Marcotty

Journal article  |  2021  |  PLOS NEGLECTED TROPICAL DISEASES

BACKGROUND: Cystic echinococcosis (CE) is an important cause of human morbidity and mortality worldwide, particularly in Morocco a..

Kathmandu Declaration on Cysticercosis : Towards Eradication

Basant Pant, Sharad Onta, Sushil Nath Pyakurel, Biraj Man Karmacharya, Bimal Kumar Nirmal, Ana Flisser, Marshall Lightowlers

Journal article  |  2021  |  Annapurna Journal of Health Sciences

In December 2018, an international conference on cysticercosis was held in Kathmandu,Nepal with the theme, “Towards Eradication”. ..

Performance of Ag-ELISA in the diagnosis of Taenia solium cysticercosis in naturally infected pigs in Tanzania

Mwemezi L Kabululu, Maria V Johansen, James ED Mlangwa, Ernatus M Mkupasi, Uffe C Braae, Chiara Trevisan, Angela Colston, Claudia Cordel, Marshall W Lightowlers, Helena A Ngowi

Journal article  |  2020  |  PARASITES & VECTORS

BACKGROUND: Taenia solium is a zoonotic parasite responsible for neurocysticercosis-a major cause of late-onset acquired epilepsy ..

Immunological responses and potency of the EG95NC(-) recombinant sheep vaccine against cystic echinococcosis

M Jazouli, MW Lightowlers, Z Bamouh, CG Gauci, K Tadlaoui, MM Ennaji, M Elharrak

Journal article  |  2020  |  PARASITOLOGY INTERNATIONAL

Cystic echinococcosis (CE) is a zoonotic disease caused by the cestode parasite Echinococcus granulosus. The disease has an import..