Kathleen Nicholls

Efficacy of the pharmacologic chaperone migalastat in a subset of male patients with the classic phenotype of Fabry disease and migalastat-amenable variants: data from the phase 3 randomized, multicenter, double-blind clinical trial and extension study

Dominique P Germain, Kathy Nicholls, Roberto Giugliani, Daniel G Bichet, Derralynn A Hughes, Laura M Barisoni, Robert B Colvin, J Charles Jennette, Nina Skuban, Jeffrey P Castelli, Elfrida Benjamin, Jay A Barth, Christopher Viereck

Journal article  |  2019  |  Genetics in Medicine

PURPOSE: Outcomes in patients with Fabry disease receiving migalastat during the phase 3 FACETS trial (NCT00925301) were evaluated..

Safety of switching to Migalastat from enzyme replacement therapy in Fabry disease: Experience from the Phase 3 ATTRACT study

Derralynn A Hughes, Kathleen Nicholls, Gere Sunder-Plassmann, Ana Jovanovic, Ulla Feldt-Rasmussen, Raphael Schiffmann, Robert Giugliani, Vipul Jain, Chris Viereck, Jeffrey P Castelli, Nina Skuban, Jay A Barth, Daniel G Bichet

Journal article  |  2019  |  American Journal of Medical Genetics Part A

Pegunigalsidase alfa, a novel PEGylated enzyme replacement therapy for Fabry disease, provides sustained plasma concentrations and favorable pharmacodynamics: A 1-year Phase 1/2 clinical trial

Raphael Schiffmann, Ozlem Goker-Alpan, Myrl Holida, Pilar Giraldo, Laura Barisoni, Robert B Colvin, Charles J Jennette, Gustavo Maegawa, Simeon A Boyadjiev, Derlis Gonzalez, Kathy Nicholls, Ahmad Tuffaha, Mohamed G Atta, Bonita Rup, Martha R Charney, Alona Paz, Mali Szlaifer, Sari Alon, Einat Brill-Almon, Raul Chertkoff, et al.

Journal article  |  2019  |  Journal of Inherited Metabolic Disease

Fatal Enteroviral Encephalitis in a Patient with Common Variable Immunodeficiency Harbouring a Novel Mutation in NFKB2

Charlotte A Slade, Catriona McLean, Thomas Scerri, Binh Giang Tran, Steven Megaloudis, Alexander Strathmore, Jessica C Tempany, Katherine Nicholls, Colleen D'Arcy, Melanie Bahlo, Philip D Hodgkin, Jo A Douglass, Vanessa L Bryant

Journal article  |  2019  |  Journal of Clinical Immunology

Cardio- Renal Outcomes With Long- Term Agalsidase Alfa Enzyme Replacement Therapy: A 10-Year Fabry Outcome Survey (FOS) Analysis

Uma Ramaswami, Michael Beck, Derralynn Hughes, Christoph Kampmann, Jaco Botha, Guillem Pintos-Morell, Michael L West, Dau-Ming Niu, Kathy Nicholls, Roberto Giugliani

Journal article  |  2019  |  Drug Design, Development and Therapy

Management of refractory lupus nephritis: challenges and solutions

JH Yo, TD Barbour, K Nicholls

Journal article  |  2019  |  Open Access Rheumatology: Research and Reviews

Critical care usage after major gastrointestinal and liver surgery: a prospective, multicentre observational study.

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Journal article  |  2019  |  British Journal of Anaesthesia

BACKGROUND: Patient selection for critical care admission must balance patient safety with optimal resource allocation. This study..

Elevated Lyso-Gb3 Suggests the R118C GLA Mutation Is a Pathological Fabry Variant.

Andrew Talbot, Kathy Nicholls

Journal article  |  2019  |  JIMD reports

BACKGROUND: Fabry disease (FD), an X-linked lysosomal storage disease, results from an α-galactosidase A deficiency and altered sp..

Association between peri-operative angiotensin-converting enzyme inhibitors and angiotensin-2 receptor blockers and acute kidney injury in major elective non-cardiac surgery: a multicentre, prospective cohort study.

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Journal article  |  2018  |  Anaesthesia

The peri-operative use of angiotensin-converting enzyme inhibitors or angiotensin-2 receptor blockers is thought to be associated ..

Absence of renal phenotype in hereditary haemorrhagic telangiectasia

Lachlan Healy, Kathleen Nicholls, Robert Gibson, Damien Stella, Michael Bogwitz, Jessica Taylor, Maie Walsh, Liz Donaldson, Ingrid Winship

Journal article  |  2018  |  Internal Medicine Journal

Allergic rhinoconjunctivitis: Allergen-specific immunotherapy options in Australia

S Chan, K Nicholls

Journal article  |  2018  |  Medicine Today

Phenotypic characteristics of the p.Asn215Ser (p.N215S) GLA mutation in male and female patients with Fabry disease: A multicenter Fabry Registry study

Dominique P Germain, Eva Brand, Alessandro Burlina, Franco Cecchi, Scott C Garman, Judy Kempf, Dawn A Laney, Ales Linhart, Laszlo Marodi, Kathy Nicholls, Alberto Ortiz, Federico Pieruzzi, Suma P Shankar, Stephen Waldek, Christoph Wanner, Ana Jovanovic

Journal article  |  2018  |  Molecular Genetics & Genomic Medicine

Delayed Diagnosis and Complications of Predominantly Antibody Deficiencies in a Cohort of Australian Adults

Charlotte A Slade, Julian J Bosco, Tran Binh Giang, Elizabeth Kruse, Robert G Stirling, Paul U Cameron, Fiona Hore-Lacy, Michael F Sutherland, Sara L Barnes, Stephen Holdsworth, Samar Ojaimi, Gary A Unglik, Joseph De Luca, Mittal Patel, Jeremy McComish, Kymble Spriggs, Yang Tran, Priscilla Auyeung, Katherine Nicholls, Robyn E O'Hehir, et al.

Journal article  |  2018  |  Frontiers in Immunology

Migalastat improves diarrhea in patients with Fabry disease: clinical-biomarker correlations from the phase 3 FACETS trial

Raphael Schiffmann, Daniel G Bichet, Ana Jovanovic, Derralynn A Hughes, Roberto Giugliani, Ulla Feldt-Rasmussen, Suma P Shankar, Laura Barisoni, Robert B Colvin, J Charles Jennette, Fred Holdbrook, Andrew Mulberg, Jeffrey P Castelli, Nina Skuban, Jay A Barth, Kathleen Nicholls

Journal article  |  2018  |  Orphanet Journal of Rare Diseases

Improvement of Fabry Disease-Related Gastrointestinal Symptoms in a Significant Proportion of Female Patients Treated with Agalsidase Beta: Data from the Fabry Registry

William R Wilcox, Ulla Feldt-Rasmussen, Ana Maria Martins, Alberto Ortiz, Roberta M Lemay, Ana Jovanovic, Dominique P Germain, Carmen Varas, Katherine Nicholls, Frank Weidemann, Robert J Hopkin

Journal article  |  2018  |  JIMD reports

Mastocytosis: a case series of 107 consecutive patients

H Bhullar, R Martyres, K Nicholls, G Varigos, J Douglass, A Saracino

Journal article  |  2018  |  British Journal of Dermatology

Migalastat for the treatment of Fabry disease

Gere Sunder-Plassmann, Raphael Schiffmann, Kathleen Nicholls

Journal article  |  2018  |  Expert Opinion on Orphan Drugs

A simple method for quantification of plasma globotriaosylsphingosine: Utility for Fabry disease

Andrew Talbot, Kathy Nicholls, Janice M Fletcher, Maria Fuller

Journal article  |  2017  |  Molecular Genetics and Metabolism

Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study

Derralynn A Hughes, Kathleen Nicholls, Suma P Shankar, Gere Sunder-Plassmann, David Koeller, Khan Nedd, Gerard Vockley, Takashi Hamazaki, Robin Lachmann, Toya Ohashi, Iacopo Olivotto, Norio Sakai, Patrick Deegan, David Dimmock, Francois Eyskens, Dominique P Germain, Ozlem Goker-Alpan, Eric Hachulla, Ana Jovanovic, Charles M Lourenco, et al.

Journal article  |  2017  |  Journal of Medical Genetics

Bull's eye and pigment maculopathy are further retinal manifestations of an abnormal Bruch's membrane in Alport syndrome

Judy Savige, Yanyan Wang, Andrew Crawford, James Smith, Andrew Symons, Heather Mack, Kathy Nicholls, Diane Wilson, Deb Colville

Journal article  |  2017  |  Ophthalmic Genetics

Sleep Disturbance, Obstructive Sleep Apnoea and Abnormal Periodic Leg Movements: Very Common Problems in Fabry Disease

Andrew Talbot, Gary Hammerschlag, Jeremy Goldin, Kathy Nicholls

Journal article  |  2017  |  JIMD reports

Safety of Nonsteroidal Anti-inflammatory Drugs in Major Gastrointestinal Surgery: A Prospective, Multicenter Cohort Study.

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Journal article  |  2017  |  World Journal of Surgery

BACKGROUND: Significant safety concerns remain surrounding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) following gast..

An unusual urticarial eruption: Familial cold autoinflammatory syndrome

Rebecca Nguyen, Aaron Robinson, Katherine Nicholls, George Varigos, Con Dolianitis

Journal article  |  2016  |  Australasian Journal of Dermatology

Immunoglobulin E-Mediated Hypersensitivity Reaction to Ketamine

John Ozcan, Katherine Nicholls, Karin Jones

Journal article  |  2016  |  Pain Practice

Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat

DP Germain, DA Hughes, K Nicholls, DG Bichet, R Giugliani, WR Wilcox, C Feliciani, SP Shankar, F Ezgu, H Amartino, D Bratkovic, U Feldt-Rasmussen, K Nedd, U Sharaf El Din, CM Lourenco, M Banikazemi, J Charrow, M Dasouki, D Finegold, P Giraldo, et al.

Journal article  |  2016  |  New England Journal of Medicine

A 15-year perspective of the fabry outcome survey

R Giugliani, DM Niu, U Ramaswami, M West, D Hughes, C Kampmann, G Pintos-Morell, K Nicholls, JM Schenk, M Beck

Journal article  |  2016  |  Journal of Inborn Errors of Metabolism and Screening

Fabry in the older patient: Clinical consequences and possibilities for treatment

Olivier Lidove, Frederic Barbey, Dau-Ming Niu, Eva Brand, Kathleen Nicholls, Svetlana Bizjajeva, Derralynn A Hughes

Journal article  |  2016  |  Molecular Genetics and Metabolism

Multicentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery.

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Journal article  |  2016  |  British Journal of Surgery

BACKGROUND: There is currently conflicting evidence surrounding the effects of obesity on postoperative outcomes. Previous studies..

Single-dose rituximab in refractory lupus nephritis

P Kotagiri, A Martin, P Hughes, G Becker, K Nicholls

Journal article  |  2016  |  Internal Medicine Journal

Safety and efficacy of a novel short occlusive regimen of imiquimod for selected non-melanotic skin lesions in renal transplant patients

G Das, B Tan, K Nicholls

Journal article  |  2016  |  Internal Medicine Journal

Retinal disease in the C3 glomerulopathies and the risk of impaired vision

J Savige, L Amos, Frank Ierino, HG Mack, RC Andrew Symons, P Hughes, K Nicholls, D Colville

Journal article  |  2016  |  Ophthalmic Genetics

Lipiduria - with special relevance to Fabry disease

Gavin J Becker, Kathleen Nicholls

Journal article  |  2015  |  Clinical Chemistry and Laboratory Medicine (CCLM)

Foot screening in a dialysis unit - a pilot educational project

Joan Leo, Kathleen Nicholls

Journal article  |  2015  |  Renal Society of Australasia Journal

Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active alpha-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase

David G Warnock, Daniel G Bichet, Myrl Holida, Ozlem Goker-Alpan, Kathy Nicholls, Mark Thomas, Francois Eyskens, Suma Shankar, Mathews Adera, Sheela Sitaraman, Richie Khanna, John J Flanagan, Brandon A Wustman, Jay Barth, Carrolee Barlow, Kenneth J Valenzano, David J Lockhart, Pol Boudes, Franklin K Johnson

Journal article  |  2015  |  PLOS ONE

HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome

Rasheed A Gbadegesin, Adebowale Adeyemo, Nicholas JA Webb, Larry A Greenbaum, Asiri Abeyagunawardena, Shenal Thalgahagoda, Arundhati Kale, Debbie Gipson, Tarak Srivastava, Jen-Jar Lin, Deepa Chand, Tracy E Hunley, Patrick D Brophy, Arvind Bagga, Aditi Sinha, Michelle N Rheault, Joanna Ghali, Kathy Nicholls, Elizabeth Abraham, Halima S Janjua, et al.

Journal article  |  2015  |  Journal of the American Society of Nephrology

Adoptive T Cell Immunotherapy for Treatment of Ganciclovir-Resistant Cytomegalovirus Disease in a Renal Transplant Recipient

N Macesic, D Langsford, K Nicholls, P Hughes, DJ Gottlieb, L Clancy, E Blyth, K Micklethwaite, B Withers, S Majumdar, S Fleming, J Sasadeusz

Journal article  |  2015  |  American Journal of Transplantation

Cardiovascular outcomes in Fabry disease are linked to severity of chronic kidney disease.

Andrew S Talbot, Nigel T Lewis, Kathy M Nicholls

Journal article  |  2015  |  Heart

OBJECTIVES: Assess the impact of end-stage renal disease (chronic kidney disease stage 5 (CKD5)) on cardiovascular outcomes in pat..

IMPROVING TREATMENT DELIVERY IN IMMUNOGLOBULIN DEFICIENCY: A QUALITY IMPROVEMENT SURVEY

Josh Chatelier, Kymble Spriggs, Daniel Lichtblau, Jeremy McComish, Katherine Nicholls, Gary Unglik, Maia Brewerton, Charlotte Slade, Jo Douglass

Journal article  |  2014  |  INTERNAL MEDICINE JOURNAL

SEVERITY OF FABRY NEPHROPATHY - A MARKER OF CARDIOVASCULAR OUTCOME: 10-YEAR DATA FROM AN AUSTRALIAN COHORT ON ENZYME REPLACEMENT THERAPY

A Talbot, K Nicholls

Journal article  |  2014  |  NEPHROLOGY

Efficacy and Safety of Abatacept in Lupus Nephritis A Twelve-Month, Randomized, Double-Blind Study

Richard Furie, Kathy Nicholls, Tien-Tsai Cheng, Frederic Houssiau, Ruben Burgos-Vargas, Shun-Le Chen, Jan L Hillson, Stephanie Meadows-Shropshire, Michael Kinaszczuk, Joan T Merrill

Journal article  |  2014  |  Arthritis & Rheumatology

Antiepileptic Medications Increase Osteoporosis Risk in Male Fabry Patients: Bone Mineral Density in an Australian Cohort

Andrew Talbot, Joanna R Ghali, Kathy Nicholls

Book Chapter  |  2014  |  JIMD Reports

A clinical approach to allergic rhinitis

E Lin, K Nicholls

Journal article  |  2014  |  Medicine Today

Changes in plasma and urine globotriaosylceramide levels do not predict Fabry disease progression over 1 year of agalsidase alfa

Raphael Schiffmann, Markus Ries, Derek Blankenship, Kathy Nicholls, Atul Mehta, Joe TR Clarke, Robert D Steiner, Michael Beck, Bruce A Barshop, William Rhead, Michael West, Rick Martin, David Amato, Nitin Nair, Pedro Huertas

Journal article  |  2013  |  Genetics in Medicine

Analysis of left ventricular mass in untreated men and in men treated with agalsidase-beta: data from the Fabry Registry

Dominique P Germain, Frank Weidemann, Ademola Abiose, Manesh R Patel, Marta Cizmarik, J Alexander Cole, Dana Beitner-Johnson, Karelle Benistan, Gustavo Cabrera, Joel Charrow, Ilkka Kantola, Ales Linhart, Kathy Nicholls, Markus Niemann, C Ronald Scott, Katherine Sims, Stephen Waldek, David G Warnock, Joerg Strotmann

Journal article  |  2013  |  Genetics in Medicine

Kidney transplantation and enzyme replacement therapy in patients with Fabry disease

Markus Cybulla, Christine Kurschat, Michael West, Kathy Nicholls, Joan Torras, Gere Sunder-Plassmann, Sandro Feriozzi

Journal article  |  2013  |  Journal of Nephrology

A Phase 2 study of migalastat hydrochloride in females with Fabry disease: Selection of population, safety and pharmacodynamic effects

R Giugliani, S Waldek, DP Germain, K Nicholls, DG Bichet, JK Simosky, AC Bragat, JP Castelli, ER Benjamin, PF Boudes

Journal article  |  2013  |  Molecular Genetics and Metabolism

Migalastat HCl Reduces Globotriaosylsphingosine (Lyso-Gb(3)) in Fabry Transgenic Mice and in the Plasma of Fabry Patients

Brandy Young-Gqamana, Nastry Brignol, Hui-Hwa Chang, Richie Khanna, Rebecca Soska, Maria Fuller, Sheela A Sitaraman, Dominique P Germain, Roberto Giugliani, Derralynn A Hughes, Atul Mehta, Kathy Nicholls, Pol Boudes, David J Lockhart, Kenneth J Valenzano, Elfrida R Benjamin

Journal article  |  2013  |  PLoS One

Safety and pharmacodynamic effects of a pharmacological chaperone on alpha-galactosidase A activity and globotriaosylceramide clearance in Fabry disease: report from two phase 2 clinical studies

Dominique P Germain, Roberto Giugliani, Derralynn A Hughes, Atul Mehta, Kathy Nicholls, Laura Barisoni, Charles J Jennette, Alexander Bragat, Jeff Castelli, Sheela Sitaraman, David J Lockhart, Pol F Boudes

Journal article  |  2012  |  Orphanet Journal of Rare Diseases

Increased arterial stiffness is associated with high cardiovascular mortality in male Fabry patients

Kathleen Nicholls

Journal article  |  2012  |  Journal of Inherited Metabolic Disease

The Effectiveness of Long-Term Agalsidase Alfa Therapy in the Treatment of Fabry Nephropathy

Sandro Feriozzi, Joan Torras, Markus Cybulla, Kathy Nicholls, Gere Sunder-Plassmann, Michael West

Journal article  |  2012  |  Clinical Journal of the American Society of Nephrology

Effect of Reduced Agalsidase Beta Dosage in Fabry Patients: The Australian Experience

Joanna Ghali, Kathy Nicholls, Charles Denaro, David Sillence, Ian Chapman, Jack Goldblatt, Mark Thomas, Janice Fletcher

Book Chapter  |  2012  |  JIMD Reports

Carpal Tunnel Syndrome in Fabry Disease

Joanna Ghali, Anand Murugasu, Timothy Day, Kathy Nicholls

Book Chapter  |  2012  |  JIMD Reports

Severe Infusion Reactions to Fabry Enzyme Replacement Therapy: Rechallenge After Tracheostomy

K Nicholls, K Bleasel, G Becker

Book Chapter  |  2012  |  JIMD Reports

Targeted urine microscopy in Anderson-Fabry Disease: a cheap, sensitive and specific diagnostic technique

Mathu Selvarajah, Kathy Nicholls, Tim D Hewitson, Gavin J Becker

Journal article  |  2011  |  Nephrology, Dialysis, Transplantation

Cardiovascular Events in Patients With Fabry Disease Natural History Data From the Fabry Registry

Manesh R Patel, Franco Cecchi, Marta Cizmarik, Ilkka Kantola, Ales Linhart, Kathy Nicholls, Joerg Strotmann, Jose Tallaj, Chien Tran Thi, Michael L West, Dana Beitner-Johnson, Ademola Abiose

Journal article  |  2011  |  Journal of the American College of Cardiology

Ethnicity and lupus nephritis: an Australian single centre study

C Ong, K Nicholls, G Becker

Journal article  |  2011  |  Internal Medicine Journal

Low-dose valaciclovir and cytomegalovirus immunoglobulin to prevent cytomegalovirus disease in high-risk renal transplant recipients

Nigel D Toussaint, Marcus BP Tan, Kathy Nicholls, Rowan G Walker, Solomon J Cohney

Journal article  |  2011  |  Nephrology

Therapeutic goals in the treatment of Fabry disease

Atul Mehta, Michael L West, Guillem Pintos-Morell, Ricardo Reisin, Kathy Nicholls, Luis E Figuera, Rossella Parini, Luiz R Carvalho, Christoph Kampmann, Gregory M Pastores, Olivier Lidove

Journal article  |  2010  |  Genetics in Medicine

Effects of enzyme replacement therapy in Fabry disease-A comprehensive review of the medical literature

Olivier Lidove, Michael L West, Guillem Pintos-Morell, Ricardo Reisin, Kathy Nicholls, Luis E Figuera, Rossella Parini, Luiz R Carvalho, Christoph Kampmann, Gregory M Pastores, Atul Mehta

Journal article  |  2010  |  Genetics in Medicine

Prevention and management of chronic kidney disease in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Cost-effectiveness and socioeconomic implications of prevention and management of chronic kidney disease in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Assessment of kidney function in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Agalsidase Alfa and Kidney Dysfunction in Fabry Disease

Michael West, Kathy Nicholls, Atul Mehta, Joe TR Clarke, Robert Steiner, Michael Beck, Bruce A Barshop, William Rhead, Robert Mensah, Markus Ries, Raphael Schiffmann

Journal article  |  2009  |  Journal of the American Society of Nephrology

Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis.

Gerald B Appel, Gabriel Contreras, Mary Anne Dooley, Ellen M Ginzler, David Isenberg, David Jayne, Lei-Shi Li, Eduardo Mysler, Jorge Sánchez-Guerrero, Neil Solomons, David Wofsy, undefined Aspreva Lupus Management Study Group

Journal article  |  2009  |  Journal of the American Society of Nephrology

Recent studies have suggested that mycophenolate mofetil (MMF) may offer advantages over intravenous cyclophosphamide (IVC) for th..

Thrombotic thrombocytopenic purpura is associated with a high relapse rate after plasma exchange: a single-centre experience

N Frawley, AP Ng, K Nicholls, S Cohney, C Hogan, A Grigg

Journal article  |  2009  |  Intern. Med. J.

Cardiovascular testing in Fabry disease: exercise capacity reduction, chronotropic incompetence and improved anaerobic threshold after enzyme replacement

T Lobo, J Morgan, A Bjorksten, K Nicholls, L Grigg, E Centra, G Becker

Journal article  |  2008  |  Internal Medicine Journal

Conversion of cyclosporine to tacrolimus in stable renal allograft recipients: Quantification of effects on the severity of gingival enlargement and hirsutism and patient-reported outcomes

Rowan G Walker, Stephen Cottrell, Kathleen Sharp, Rosamaria Tripodi, Kathy M Nicholls, Ian Fraser, George A Varigos, Belinda E Butcher

Journal article  |  2007  |  Nephrology

Neurology of Fabry disease

M Low, K Nicholls, N Tubridy, P Hand, D Velakoulis, L Kiers, P Mitchell, G Becker

Journal article  |  2007  |  Internal Medicine Journal

Anti-CD20 antibody in thrombotic thrombocytopenic purpura refractory to plasma exchange

KV Chow, R Carroll, P Branley, K Nicholls, G Becker, C Hogan

Journal article  |  2007  |  Internal Medicine Journal

Fabry disease: Baseline medical characteristics of a cohort of 1765 males and females in the Fabry Registry

CM Eng, J Fletcher, WR Wilcox, S Waldek, CR Scott, DO Sillence, F Breunig, J Charrow, DP Germain, K Nicholls, M Banikazemi

Conference Proceedings  |  2007  |  Journal of Inherited Metabolic Disease

Prevention of progression of kidney disease: diabetic nephropathy - CARI guidelines

Kathy Nicholls

Journal article  |  2007  |  Australian family physician

The CARI guidelines. Prevention of progression of kidney disease.

David Harris, Merlin Thomas, David Johnson, Kathy Nicholls, Adrian Gillin, undefined Caring for Australasians with Renal Impairment (CARI)

Conference Proceedings  |  2006  |  Nephrology

Diabetic nephropathy--how might we prevent, retard, or cope with it?

Kathy Nicholls

Journal article  |  2005  |  Australian Family Physician

BACKGROUND: Working life for most Australian doctors in adult practice is heavily involved with diabetes and its complications. Th..

A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients.

Raymund R Razonable, Robert A Brown, Atul Humar, Emma Covington, Emma Alecock, Carlos V Paya, undefined PV16000 Study Group

Journal article  |  2005  |  The Journal of Infectious Diseases

In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observ..

Actuarial survival in Australian male patients with Fabry's disease [3]

K Nicholls, G Becker

Journal article  |  2005  |  Internal Medicine Journal

Actuarial survival in Australian male patients with Fabry's disease

K Nicholls, G Becker

Journal article  |  2005  |  Internal Medicine Journal

Ophthalmological manifestations of Fabry disease: A survey of patients at the Royal Melbourne Fabry Disease Treatment Centre

TT Nguyen, T Gin, K Nicholls, M Low, J Galanos, A Crawford

Journal article  |  2005  |  Clinical and Experimental Ophthalmology

Cardiac involvement in Fabry's disease.

Kathy Nicholls

Journal article  |  2005  |  Heart, Lung and Circulation

Clinical Fabry's disease is due to any of multiple mutations in the X-linked alpha-galactosidase gene. These mutations are kindred..

Sirolimus: A single center experience in combination with calcineurin inhibitors

R Masterson, M Leikis, V Perkovic, K Nicholls, R Walker

Journal article  |  2003  |  Transplantation Proceedings

Clinical features of Fabry's disease in Australian patients

J Galanos, K Nicholls, L Grigg, L Kiers, A Crawford, G Becker

Journal article  |  2002  |  Internal Medicine Journal

Glomerular size and global glomerulosclerosis in normal Caucasian donor kidneys: effects of aging and gender.

Mingxi Li, Kathy M Nicholls, Gavin J Becker

Journal article  |  2002  |  Journal of Nephrology

BACKGROUND: To assess the effects of aging and gender on glomerular size and global glomerulosclerosis (GS) and evaluate the relat..

Risk factors for late renal allograft dysfunction: Effects of baseline glomerular size

MX Li, KM Nicholls, GJ Becker

Journal article  |  2002  |  Journal of Nephrology

Alteplase: A safe and cost-effective alternative to urokinase [1]

V Reginato, KM Nicholls

Journal article  |  2002  |  Journal of Pharmacy Practice and Research

Hyaluronan and rat renal fibroblasts: In vitro studies

E Pedagogos, TD Hewitson, KM Nicholls, GJ Becker

Journal article  |  2001  |  Nephron

Sirolimus does not potentiate indices of chronic cyclosporin nephrotoxicity

AWC Tang, RG Walker, KM Nicholls, GJ Becker

Journal article  |  2001  |  Transplantation Proceedings

Human renal fibroblast contraction of collagen I lattices is an integrin-mediated process

KJ Kelynack, TD Hewitson, KM Nicholls, IA Darby, GJ Becker

Journal article  |  2000  |  Nephrology Dialysis Transplantation

Influence of anti-rejection therapy on the timing of cytomegalovirus disease and other infections in renal transplant recipients

B Jamil, KM Nicholls, GJ Becker, RG Walker

Journal article  |  2000  |  Clinical Transplantation

Impact of acute rejection therapy on infections and malignancies in renal transplant recipients

B Jamil, K Nicholls, GJ Becker, RG Walker

Journal article  |  1999  |  Transplantation

Renal myofibroblasts contract collagen I matrix lattices in vitro

KJ Kelynack, TD Hewitson, E Pedagogos, KM Nicholls, GJ Becker

Journal article  |  1999  |  American Journal of Nephrology

Cell kinetics and tissue contraction following renal parenchymal cell death

KJ Kelynack, TD Hewitson, KM Nicholls, GJ Becker, CL Jones

Journal article  |  1998  |  Nephrology

Effects of perindopril on renal histomorphometry in diabetic subjects with microalbuminuria: A 3-year placebo-controlled biopsy study

A Nankervis, K Nicholls, G Kilmartin, P Allen, S Ratnaike, FIR Martin

Conference Proceedings  |  1998  |  Metabolism: Clinical and Experimental

Myofibroblast involvement in chronic transplant rejection

E Pedagogos, TD Hewitson, RG Walker, KM Nicholls, GJ Becker

Journal article  |  1997  |  Transplantation

Renal myofibroblasts contract solidified collagen matrix.

K Kelynack, T Hewitson, E Pedagogos, K Nicholls, G Becker

Journal article  |  1997  |  JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Myofibroblasts and arteriolar sclerosis in human diabetic nephropathy

E Pedagogos, T Hewitson, I Fraser, K Nicholls, G Becker

Journal article  |  1997  |  American Journal of Kidney Diseases

Myofibroblasts correlate with fibrotic markers in diabetic nephropathy.

E Pedagogos, I Fraser, T Hewitson, K Nicholls, G Becker

Journal article  |  1997  |  KIDNEY INTERNATIONAL

The myofibroblast in acute transplant rejection.

E Pedagogos, T Hewitson, K Nicholls, R Walker, G Becker

Journal article  |  1997  |  KIDNEY INTERNATIONAL

Significance of focal and segmental hyalinosis and sclerosis (FSHS) in IgA nephropathy.

DK Packham, HD Yan, TD Hewitson, KM Nicholls, PS KincaidSmith, GJ Becker

Journal article  |  1996  |  KIDNEY INTERNATIONAL

The significance of focal and segmental hyalinosis and sclerosis (FSHS) and nephrotic range proteinuria in IgA nephropathy

DK Packham, HD Yan, TD Hewitson, KM Nicholls, KF Fairley, P KincaidSmith, GJ Becker

Journal article  |  1996  |  Clinical Nephrology

Kidney transplantation from living non-related donors.

MA Cunningham, DM Francis, R Millar, KM Nicholls, I Fraser, RG Walker

Journal article  |  1996  |  Medical Journal of Australia

Lymphoproliferative disorder post renal transplantation: Recent experience at a single centre

E Pedagogos, J Dowling, S Rockman, K Nicholls, I Fraser, R Walker

Journal article  |  1996  |  Nephrology

ANTIPHOSPHOLIPID SYNDROME AND RENAL THROMBOTIC MICROANGIOPATHY

K NICHOLLS, P KINCAIDSMITH

Journal article  |  1995  |  Journal of Nephrology

ACUTE-RENAL-FAILURE IN IGA NEPHROPATHY

DK PACKHAM, TD HEWITSON, HD YAN, CE ELLIOTT, K NICHOLLS, GJ BECKER

Journal article  |  1994  |  Clinical Nephrology

KAPOSIS-SARCOMA POST RENAL-TRANSPLANTATION

E PEDAGOGOS, K NICHOLLS, J DOWLING, G BECKER

Journal article  |  1994  |  Australian and New Zealand Journal of Medicine

LIVE DONOR RENAL-TRANSPLANTATION WITH LOW-DOSE TRIPLE IMMUNOSUPPRESSION

DMA FRANCIS, RJ MILLAR, RG WALKER, K NICHOLLS, H POWELL, C JONES, R KOCKELBERGH, G BECKER

Journal article  |  1992  |  Transplantation Proceedings

LUPUS NEPHRITIS AND PREGNANCY

DK PACKHAM, SS LAM, K NICHOLLS, KF FAIRLEY, PS KINCAIDSMITH

Journal article  |  1992  |  QJM: An International Journal of Medicine

Nutritional status in alcoholism

B Wood, KM Nicholls, KJ Breen

Journal article  |  1992  |  Journal of Human Nutrition and Dietetics

[IgA nephropathy in Chinese and Australian patients: a comparison between clinical and pathological features].

L Li, K Tao, K Nicholls, P Kincaid-Smith

Journal article  |  1991  |  Zhonghua yi xue za zhi

The clinical and pathological data were compared between 88 Chinese and 88 Australian patients with IgA nephropathy, whose age, se..

RENAL THROMBOTIC MICROVASCULAR DISEASE ASSOCIATED WITH LUPUS ANTICOAGULANT

P KINCAIDSMITH, K NICHOLLS

Journal article  |  1990  |  Nephron

Plasma exchange in progressive IgA nephropathy.

K Nicholls, G Becker, R Walker, C Wright, P Kincaid-Smith

Journal article  |  1990  |  Journal of Clinical Apheresis

A therapeutic trial of plasma exchange was performed in 13 patients with documented progressive IgA nephropathy. Comparison of the..

POLYMORPHS INFILTRATE GLOMERULI IN MESANGIAL IGA GLOMERULONEPHRITIS

P KINCAIDSMITH, K NICHOLLS, I BIRCHALL

Journal article  |  1989  |  Kidney International

Severe flank pain as the predominant symptom of IgA nephropathy.

P Kincaid-Smith, K Nicholls

Journal article  |  1989  |  American Journal of Kidney Diseases

EXPRESSION OF COMPLEMENT-3 RECEPTORS (CR-1 AND CR3) ON NEUTROPHILS AND ERYTHROCYTES IN PATIENTS WITH IGA NEPHROPATHY

K TAO, K NICHOLLS, S ROCKMAN, P KINCAIDSMITH

Journal article  |  1989  |  Clinical Nephrology

ADVANCED GLYCOSYLATION END-PRODUCTS IN EXPERIMENTAL MURINE DIABETIC NEPHROPATHY - EFFECT OF ISLET ISOGRAFTING AND OF AMINOGUANIDINE

K NICHOLLS, TE MANDEL

Journal article  |  1989  |  Laboratory Investigation

CLINICOPATHOLOGICAL ASSOCIATIONS IN MESANGIAL IGA NEPHROPATHY

WM BENNETT, K NICHOLLS, P KINCAIDSMITH

Journal article  |  1987  |  American Journal of Nephrology

Factors determining renal response to water immersion in non-excretor cirrhotic patients.

KM Nicholls, MD Shapiro, BS Groves, RW Schrier

Journal article  |  1986  |  Kidney International

Non-excretor cirrhotic patients, defined by their inability to normally excrete a standard water load, display variable responses ..

Role of glomerular filtration rate in the impaired sodium and water excretion of patients with the nephrotic syndrome.

MD Shapiro, KM Nicholls, BM Groves, RW Schrier

Journal article  |  1986  |  American Journal of Kidney Diseases

Hemodynamic and hormonal factors were monitored in nine patients with nephrotic syndrome who were evaluated relative to their capa..

Sodium excretion in advanced cirrhosis: effect of expansion of central blood volume and suppression of plasma aldosterone.

KM Nicholls, MD Shapiro, R Kluge, HM Chung, DG Bichet, RW Schrier

Journal article  |  1986  |  Hepatology

Sodium excretion in 13 patients with decompensated cirrhosis was measured under baseline conditions of water loading (n = 13) and ..

Interrelationship between cardiac output and vascular resistance as determinants of effective arterial blood volume in cirrhotic patients.

MD Shapiro, KM Nicholls, BM Groves, R Kluge, HM Chung, DG Bichet, RW Schrier

Journal article  |  1985  |  Kidney International

The effect of head-out water immersion (HWI) in decompensated cirrhotic patients to correct sodium and water excretion has been fo..

Elevated plasma norepinephrine concentrations in decompensated cirrhosis. Association with increased secretion rates, normal clearance rates, and suppressibility by central blood volume expansion.

KM Nicholls, MD Shapiro, VJ Van Putten, R Kluge, HM Chung, DG Bichet, RW Schrier

Journal article  |  1985  |  Circulation Research

Plasma norepinephrine concentrations are elevated in patients with decompensated cirrhosis, and correlate inversely with urinary s..

MALIGNANT IGA NEPHROPATHY

K NICHOLLS, RG WALKER, JP DOWLING, P KINCAIDSMITH

Journal article  |  1985  |  American Journal of Kidney Diseases

Acute renal failure in mesangial IgA nephropathy.

P Kincaid-Smith, GB Ryan, JP Dowling, K Nicholls

Journal article  |  1984  |  Contributions to nephrology

DEFECTIVE INVIVO FC-RECEPTOR AND C3B-RECEPTOR FUNCTION IN IGA NEPHROPATHY

K NICHOLLS, P KINCAIDSMITH

Journal article  |  1984  |  American Journal of Kidney Diseases

The clinical course of mesangial IgA associated nephropathy in adults.

KM Nicholls, KF Fairley, JP Dowling, P Kincaid-Smith

Journal article  |  1984  |  Quarterly Journal of Medicine

Clinical data in 244 patients with IgA nephropathy and biopsy findings in 519 biopsies (107 patients had at least two biopsies) we..

MESANGIAL IGA NEPHROPATHY

P KINCAIDSMITH, K NICHOLLS

Journal article  |  1983  |  American Journal of Kidney Diseases

Rhabdomyolysis and renal failure. Complications of narcotic abuse.

K Nicholls, JF Niall, JE Moran

Journal article  |  1982  |  Medical Journal of Australia

Massive adrenal haemorrhage complicating adrenal neoplasm.

K Nicholls

Journal article  |  1979  |  Medical Journal of Australia

Two patients presented to hospital with clinical features of acute retroperitoneal haemorrhage. In each case, laparotomy revealed ..

Transient myeloid and erythroid aplasia associated with infectious hepatitis.

FC Firkin, K Nicholls, G Whelan

Journal article  |  1978  |  BMJ