Kerry Landman

Mathematical modelling indicates that lower activity of the haemostatic system in neonates is primarily due to lower prothrombin concentration

Ivo Siekmann, Stefan Bjelosevic, Kerry Landman, Paul Monagle, Vera Ignjatovic, Edmund J Crampin

Journal article  |  2019  |  SCIENTIFIC REPORTS

Haemostasis is governed by a highly complex system of interacting proteins. Due to the central role of thrombin, thrombin generati..

Addressing Interdisciplinary Difficulties in Developmental Biology/Mathematical Collaborations: A Neural Crest Example

Donald F Newgreen, Kerry A Landman, James M Osborne

Journal article  |  2019  |  NEURAL CREST CELLS

Mathematical modeling can allow insight into the biological processes that can be difficult to access by conventional biological m..

Stochastic clonal expansion of "superstars" enhances the reserve capacity of enteric nervous system precursor cells

Dongcheng Zhang, James M Osborne, Kwaku Dad Abu-Bonsrah, Bevan L Cheeseman, Kerry A Landman, Boaz Jurkowicz, Donald F Newgreen

Journal article  |  2018  |  Developmental Biology

We quantified cell population increase in the quail embryo enteric nervous system (ENS) from E2.5 (about 1500 cells) to E12 (about..

Distinguishing cell shoving mechanisms

Pingyu Nan, Darragh M Walsh, Kerry A Landman, Barry D Hughes

Journal article  |  2018  |  PLOS ONE

Motivated by in vitro time-lapse images of ovarian cancer spheroids inducing mesothelial cell clearance, the traditional agent-bas..

A Multicellular Model of Intestinal Crypt Buckling and Fission

Axel A Almet, Barry D Hughes, Kerry A Landman, Inke S Nathke, James M Osborne

Journal article  |  2018  |  BULLETIN OF MATHEMATICAL BIOLOGY

Crypt fission is an in vivo tissue deformation process that is involved in both intestinal homeostasis and colorectal tumourigenes..

PCA Modelling of Multi-species Cell Clusters: Ganglion Development in the Gastrointestinal Nervous System

Kerry A Landman, Donald F Newgreen

Book Chapter  |  2018

A defining characteristic of the enteric nervous system (ENS) is mesoscale patterned entities called ganglia. Ganglia are clusters..

What is the optimal distribution of myelin along a single axon?

Darragh M Walsh, Kerry A Landman, Barry D Hughes

Journal article  |  2017  |  Neuroscience Letters

The myelin sheath that insulates some axons in the central nervous system allows for faster signal conduction. Previously, axons w..

Enteric nervous system formation: disproportionate stochastic clonal expansion of a few initiating vagal neural crest cells

Donald Newgreen, Dongcheng Zhang, James Osborne, Bevan Cheeseman, Benjamin Binder, Kerry Landman

Conference Proceedings  |  2017  |  MECHANISMS OF DEVELOPMENT

Differential Clonal Expansion in an Invading Cell Population: Clonal Advantage or Dumb Luck?

Donald F Newgreen, Dongcheng Zhang, Bevan L Cheeseman, Benjamin J Binder, Kerry A Landman

Conference Proceedings  |  2017  |  CELLS TISSUES ORGANS

In neoplastic cell growth, clones and subclones are variable both in size and mutational spectrum. The largest of these clones are..

Evidence for Cooperative Selection of Axons for Myelination by Adjacent Oligodendrocytes in the Optic Nerve

Darragh M Walsh, Tobias D Merson, Kerry A Landman, Barry D Hughes

Journal article  |  2016  |  PLOS ONE

The cellular mechanisms that regulate the topographic arrangement of myelin internodes along axons remain largely uncharacterized...