Richard MacIsaac

Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility

Sih Min Tan, Mark Ziemann, Vicki Thallas-Bonke, Matthew Snelson, Vinod Kumar, Adrienne Laskowski, Tuong-Vi Nguyen, Kevin Huynh, Michele V Clarke, Renata Libianto, Scott T Baker, Alison Skene, David A Power, Richard J MacIsaac, Darren C Henstridge, Rick A Wetsel, Assam El-Osta, Peter J Meikle, Scott G Wilson, Josephine M Forbes, et al.

Journal article  |  2020  |  Diabetes

The sequelae of diabetes mellitus include microvascular complications such as diabetic kidney disease (DKD), which involves glucos..

Diabetes and higher HbA1c levels are independently associated with adverse renal outcomes in inpatients following multiple hospital admissions.

N Torkamani, L Churilov, R Robbins, G Jerums, V Beik, N Radcliffe, S Patterson, R Bellomo, J Burns, GK Hart, Q Lam, DA Power, RJ MacIsaac, DF Johnson, J Zajac, EI Ekinci

Journal article  |  2020  |  Journal of Diabetes and its Complications

OBJECTIVE: To assess the association between glycaemic status prior to the first hospital presentation with developing adverse ren..

Effect of salt supplementation on sympathetic activity and endothelial function in salt sensitive type 2 diabetes.

Sara Baqar, Yee Wen Kong, Angela X Chen, Christopher O'callaghan, Richard J Macisaac, Maree Bouterakos, Gavin W Lambert, George Jerums, Elisabeth E Lambert, Elif I Ekinci

Journal article  |  2019  |  The Journal of Clinical Endocrinology & Metabolism

OBJECTIVE: To determine if sympathetic nervous system (SNS) activation and endothelial dysfunction contribute to these observation..

A physician-initiated double-blind, randomised, placebo-controlled, phase 2 study evaluating the efficacy and safety of inhibition of NADPH oxidase with the first-in-class Nox-1/4 inhibitor, GKT137831, in adults with type 1 diabetes and persistently elevated urinary albumin excretion: protocol and statistical considerations.

Anne T Reutens, Karin Jandeleit-Dahm, Merlin Thomas, Leon A Bach, Peter G Colman, Timothy ME Davis, Michael D'Emden, Elif I Ekinci, Greg Fulcher, Peter Shane Hamblin, Mark A Kotowicz, Richard J MacIsaac, Claire Morbey, David Simmons, Georgia Soldatos, Gary Wittert, Ted Wu, Mark E Cooper, Jonathan E Shaw

Journal article  |  2019  |  Contemporary Clinical Trials

PURPOSE: Kidney disease caused by type 1 diabetes can progress to end stage renal disease and can increase mortality risk. Nicotin..

Reducing glucose variability with continuous subcutaneous insulin infusion is associated with reversal of axonal dysfunction in type 1 diabetes mellitus

Jordan Kamel, Margaret Loh, Mark Cook, Richard J MacIsaac, Leslie J Roberts

Journal article  |  2019  |  Muscle & Nerve

INTRODUCTION: We assess whether improvement in control of type 1 diabetes mellitus (T1DM) with continuous subcutaneous insulin inf..

Changes in soluble tumor necrosis factor receptor type 1 levels and early renal function decline in patients with diabetes

Richard J MacIsaac, Matthew Farag, Varuni Obeyesekere, Michele Clarke, Ray Boston, Glenn M Ward, George Jerums, Elif Ekinci

Journal article  |  2019  |  Journal of Diabetes Investigation

The relationship between serial changes in soluble tumor necrosis factor receptor type 1 (TNFR1) levels and an early decline in es..

Progression of Diabetic Kidney Disease in the Absence of Albuminuria

Richard J MacIsaac, Elif I Ekinci

Journal article  |  2019  |  Diabetes Care

Correction: Diagnostic performance of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation at estimating glomerular filtration rate in adults with diabetes mellitus: a systematic review and meta-analysis protocol.

Journal article  |  2019  |  BMJ Open

Impact of type 2 diabetes on hospitalization and mortality in people with malignancy.

KV Kiburg, GM Ward, S Vogrin, K Steele, E Mulrooney, M Loh, SA McLachlan, V Sundararajan, RJ MacIsaac

Journal article  |  2019  |  Diabetic Medicine

AIM: To compare the characteristics of and outcomes for people with malignancies with and without a co-diagnosis of diabetes. METH..

Clinicians feel comfortable discussing alcohol but not illicit drug use with young adults with Type 1 diabetes: a survey of clinicians

A Pastor, J Conn, CL O'Brien, J Teng, M Loh, L Collins, RJ MacIsaac, Y Bonomo

Journal article  |  2019  |  Diabetic Medicine

Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.

Angela X Chen, John L Moran, Renata Libianto, Sara Baqar, Christopher O'Callaghan, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2019  |  Journal of Human Hypertension

High blood pressure variability (BPV) has been associated with increased cardiovascular (CV) risk. The effect of dietary salt and ..

Inflammatory proteins in diabetic kidney disease-potential as biomarkers and therapeutic targets

Angie S Xiang, Elif I Ekinci, Richard J MacIsaac

Journal article  |  2019  |  Annals of Translational Medicine

Complement C5a induces renal injury in diabetic kidney disease via mitochondrial reprogramming

MT Coughlan, S Tan, M Ziemann, M Snelson, A El-Osta, RJ MacIsaac, PJ Meikle, JM Forbes, ME Cooper, EI Ekinci, TM Woodruff

Conference Proceedings  |  2019  |  DIABETOLOGIA

SGLT2 Inhibitors Increase the Risk of Diabetic Ketoacidosis Developing in the Community and During Hospital Admission

Peter S Hamblin, Rosemary Wong, Elif Ekinci, Spiros Fourlanos, Sonali Shah, Alicia R Jones, Matthew JL Hare, Genevieve L Calder, Dilan Seneviratne Epa, Elizabeth M George, Rinky Giri, Mark A Kotowicz, Mervyn Kyi, Nicole Lafontaine, Richard J MacIsaac, Brendan J Nolan, David N O'Neal, Debra Renouf, Suresh Varadarajan, Jennifer Wong, et al.

Journal article  |  2019  |  The Journal of Clinical Endocrinology & Metabolism

CONTEXT: Diabetic ketoacidosis (DKA) has been associated with the use of sodium glucose cotransporter 2 inhibitors (SGLT2is). OBJE..

Diagnostic performance of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation at estimating glomerular filtration rate in adults with diabetes mellitus: a systematic review and meta-analysis protocol

Neda Zafari, Leonid Churilov, Richard J MacIsaac, Niloufar Torkamani, Helen Baxter, Katerina V Kiburg, Elif Ekinci

Journal article  |  2019  |  BMJ Open

INTRODUCTION: Timely detection leading to the implementation of reno-protective measures reduces the progression of diabetic kidne..

Glucose Control in Adults with Type 1 Diabetes Using a Medtronic Prototype Enhanced-Hybrid Closed-Loop System: A Feasibility Study

Melissa H Lee, Sara Vogrin, Barbora Paldus, Hannah M Jones, Varuni Obeyesekere, Catriona Sims, Sue-Anne Wyatt, Glenn M Ward, Sybil A McAuley, Richard J MacIsaac, Balasubramanian Krishnamurthy, Vijaya Sundararajan, Alicia J Jenkins, David N O'Neal

Journal article  |  2019  |  Diabetes Technology & Therapeutics

Is hyperfiltration associated with higher urine albumin-to-creatinine ratio at follow up among Indigenous Australians? The eGFR follow-up study

Elif Ekinci, Elizabeth LM Barr, Federica Barzi, Jaquelyne T Hughes, Paul D Lawton, Graham RD Jones, Wendy Hoy, Alan Cass, Mark Thomas, Ashim Sinha, George Jerums, Kerin O'Dea, Richard J MacIsaac, Louise J Maple-Brown

Journal article  |  2019  |  Journal of Diabetes and its Complications

Three Dimensional Glomerular Reconstruction: A Novel Approach to Evaluate Renal Microanatomy in Diabetic Kidney Disease

Niloufar Torkamani, George Jerums, Paul Crammer, Alison Skene, David A Power, Sianna Panagiotopoulos, Michele Clarke, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2019  |  Scientific Reports

Australia and New Zealand Islet and Pancreas Transplant Registry Annual Report 2018-Islet Donations, Islet Isolations, and Islet Transplants

Angela C Webster, James A Hedley, Patricia F Anderson, Wayne J Hawthorne, Toni Radford, Chris Drogemuller, Natasha Rogers, David Goodman, Melissa H Lee, Thomas Loudovaris, Patrick J Kelly, Philip J O'Connell, D Jane Holmes-Walker, Thomas W Kay, Richard J MacIsaac, Glenn M Ward, Ms Kathy Howe, P Toby Coates, David Torpy, Anthony Roberts, et al.

Journal article  |  2019  |  Transplantation Direct

DRIVEN TO HYPERGLYCAEMIA: ADULTS WITH TYPE 1 DIABETES HAVE HIGHER GLUCOSE LEVELS WHEN DRIVING

S Trawley, S McAuley, M Lee, B Paldus, L Bach, M Burt, P Clarke, N Cohen, P Colman, M Debock, C Hendrieckx, D Holmes-Walker, A Jenkins, J Kaye, A Keech, K Kumareswaran, R Macisaac, R McCallum, C Sims, J Speight, et al.

Conference Proceedings  |  2019  |  DIABETES TECHNOLOGY & THERAPEUTICS

Glucose Control Using a Standard Versus an Enhanced Hybrid Closed Loop System: A Randomized Crossover Study

Barbora Paldus, Melissa H Lee, Hannah M Jones, Sybil A McAuley, Jodie C Horsburgh, Kerryn L Roem, Glenn M Ward, Richard J MacIsaac, Neale Cohen, Peter G Colman, Alicia J Jenkins, David N O'Neal

Journal article  |  2019  |  Diabetes Technology & Therapeutics

Bone health in chronic kidney disease-mineral and bone disorder: a clinical case seminar and update

Jasna Aleksova, Kong W Ng, Caroline Jung, Howard Zeimer, Karen M Dwyer, Frances Milat, Richard J MacIsaac

Journal article  |  2018  |  Internal Medicine Journal

Empagliflozin as an adjunctive therapy for type 1 diabetes

Richard J MacIsaac, Melissa H Lee, Sybil A McAuley, Glenn M Ward, David N O'Neal

Journal article  |  2018  |  Annals of Translational Medicine

Mortality in People With Type 1 Diabetes, Severe Hypoglycemia, and Impaired Awareness of Hypoglycemia Referred for Islet Transplantation

Melissa H Lee, Glenn M Ward, Richard J MacIsaac, Kathy Howe, D Jane Holmes-Walker, Patricia Anderson, Toni Radford, P Toby Coates, Thomas W Kay, Philip J O'Connell, David J Goodman

Journal article  |  2018  |  Transplantation Direct

Suboptimal behaviour and knowledge regarding overnight glycaemia in adults with type 1 diabetes is common

Christina R Larsson, Andrzej S Januszewski, Rachel T McGrath, Johnny Ludvigsson, Anthony C Keech, Richard J MacIsaac, Glenn M Ward, David N O'Neal, Gregory R Fulcher, Alicia J Jenkins

Journal article  |  2018  |  Internal Medicine Journal

Systemic mastocytosis identified in two women developing fragility fractures during lactation

JJ Zhu, D Mahendran, MH Lee, J Seah, S Fourlanos, S Varadarajan, A Ghasem-Zadeh, RJ MacIsaac, E Seeman

Journal article  |  2018  |  Osteoporosis International

Contribution of cardiometabolic risk factors to estimated glomerular filtration rate decline in Indigenous Australians with and without albuminuria - the eGFR Follow-up Study

Elizabeth LM Barr, Federica Barzi, Jaquelyne T Hughes, George Jerums, Kerin O'Dea, Alex DH Brown, Elif I Ekinci, Graham RD Jones, Paul D Lawton, Ashim Sinha, Richard J MacIsaac, Alan Cass, Louise J Maple-Brown

Journal article  |  2018  |  Nephrology

Experiences of young adults with type 1 diabetes while using alcohol and recreational drugs: An interpretative phenomenological analysis (IPA) of semi-structured interviews

Adam Pastor, Casey L O'Brien, Jessie Teng, Jennifer Conn, Margaret Loh, Lisa Collins, Richard J MacIsaac, Yvonne Bonomo

Journal article  |  2018  |  Diabetes Research and Clinical Practice

Two cases of adrenocortical carcinoma

Alice Y Hong, Anneke Graf, Melissa Lee, Dilshani Jayawardene, David A Pattison, Richard J MacIsaac, Nirupa Sachithanandan

Conference Proceedings  |  2018  |  CLINICAL ENDOCRINOLOGY

Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: a randomised controlled trial protocol

Sybil A McAuley, Martin de Bock, Vijaya Sundararajan, Melissa H Lee, Barbora Paldus, Geoff R Ambler, Leon A Bach, Morton G Burt, Fergus J Cameron, Philip M Clarke, Neale D Cohen, Peter G Colman, Elizabeth A Davis, Jan M Fairchild, Christel Hendrieckx, D Jane Holmes-Walker, Jodie C Horsburgh, Alicia J Jenkins, Joey Kaye, Anthony C Keech, et al.

Journal article  |  2018  |  BMJ Open

Use of Readily Accessible inflammatory Markers to Predict Diabetic Kidney Disease

Lauren Winter, Lydia A Wong, George Jerums, Jas-Mine Seah, Michele Clarke, Sih Min Tan, Melinda T Coughlan, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2018  |  Frontiers in Endocrinology

Glucose Control Using a Standard vs. an Enhanced Hybrid Closed-Loop System—A Pilot Study

BARBORA PALDUS, MELISSAH LEE, HANNAH JONES, SYBILA MCAULEY, JODIEC HORSBURGH, KERRYNL ROEM, GLENN WARD, RICHARD MACISAAC, NEALE COHEN, PETERG COLMAN, ALICIA JENKINS, DAVIDN O'NEAL

Journal article  |  2018  |  Diabetes

Diabetic ketoacidosis in adult patients: an audit of factors influencing time to normalisation of metabolic parameters

Melissa H Lee, Genevieve L Calder, John D Santamaria, Richard J MacIsaac

Journal article  |  2018  |  Internal Medicine Journal

Pathophysiological Links Between Diabetes and Blood Pressure

Renata Libianto, Duygu Batu, Richard J MacIsaac, Mark E Cooper, Elif I Ekinci

Journal article  |  2018  |  Canadian Journal of Cardiology

Systematic review and meta-analysis of prevalence of sarcopenia in post acute inpatient rehabilitation

I Churilov, L Churilov, RJ MacIsaac, EI Ekinci

Journal article  |  2018  |  Osteoporosis International

Summary: Sarcopenia is associated with poor function and increased risk of falls and disability. This work reports a systematic re..

Diagnostic challenges in a patient with an occult insulinoma:Ga-68-DOTA-exendin-4 PET/CT and Ga-68-DOTATATE PET/CT

Elisa Bongetti, Melissa H Lee, David A Pattison, Rodney J Hicks, Richard Norris, Nirupa Sachithanandan, Richard J MacIsaac

Journal article  |  2018  |  Clinical Case Reports

High Baseline Levels of Tumor Necrosis Factor Receptor 1 Are Associated With Progression of Kidney Disease in Indigenous Australians With Diabetes: The eGFR Follow-up Study

Elizabeth LM Barr, Federica Barzi, Jaquelyne T Hughes, George Jerums, Wendy E Hoy, Kerin O'Dea, Graham RD Jones, Paul D Lawton, Alex DH Brown, Mark Thomas, Elif I Ekinci, Ashim Sinha, Alan Cass, Richard J MacIsaac, Louise J Maple-Brown

Journal article  |  2018  |  Diabetes Care

Diagnosis and Significance of Pulmonary Microvascular Disease in Diabetes

Timothy J Roberts, Andrew T Burns, Richard J MacIsaac, Andrew I MacIsaac, David L Prior, Andre La Gerche

Journal article  |  2018  |  Diabetes Care

Exercise capacity in diabetes mellitus is predicted by activity status and cardiac size rather than cardiac function: a case control study

Timothy J Roberts, Andrew T Burns, Richard J MacIsaac, Andrew I MacIsaac, David L Prior, Andre La Gerche

Journal article  |  2018  |  Cardiovascular Diabetology

Feasibility and patient acceptability of a novel artificial intelligence-based screening model for diabetic retinopathy at endocrinology outpatient services: a pilot study

Stuart Keel, Pei Ying Lee, Jane Scheetz, Zhixi Li, Mark A Kotowicz, Richard J MacIsaac, Mingguang He

Journal article  |  2018  |  Scientific Reports

Glycemic Control as Primary Prevention for Diabetic Kidney Disease

Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2018  |  Advances in Chronic Kidney Disease

Trajectories of eGFR decline over a four year period in an Indigenous Australian population at high risk of CKD-the eGFR follow up study

Federica Barzi, Graham RD Jones, Jaquelyne T Hughes, Paul D Lawton, Wendy Hoy, Kerin O'Dea, George Jerums, Richard J MacIsaac, Alan Cass, Louise J Maple-Brown

Journal article  |  2018  |  Clinical Biochemistry

Effects of Diabetes Medications Targeting the Incretin System on the Kidney

Richard J MacIsaac, Merlin C Thomas

Journal article  |  2018  |  Clinical Journal of the American Society of Nephrology

Lipid-lowering therapy use and achievement of cholesterol targets in an Australian diabetes clinic

Katerina V Kiburg, Glenn M Ward, David N O'Neal, Richard J MacIsaac

Journal article  |  2018  |  Internal Medicine Journal

Relationship between urinary sodium-to-potassium ratio and ambulatory blood pressure in patients with diabetes mellitus

Renata Libianto, John Moran, Christopher O'Callaghan, Sara Baqar, Angela X Chen, Scott T Baker, Michelle Clarke, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2018  |  Clinical and Experimental Pharmacology and Physiology

Cross-sectional associations of albuminuria among Aboriginal and Torres Strait Islander adults: the eGFR Study

JT Hughes, LJ Maple-Brown, M Thomas, PD Lawton, A Sinha, A Cass, F Barzi, GRD Jones, G Jerums, RJ MacIsaac, K O'Dea, WE Hoy

Journal article  |  2018  |  Nephrology

Long-term intra-individual variability of albuminuria in type 2 diabetes mellitus: implications for categorization of albumin excretion rate

Amanda Leong, Elif Ilhan Ekinci, Cattram Nguyen, Michele Milne, Mariam Hachem, Matthew Dobson, Richard J MacIsaac, George Jerums

Journal article  |  2017  |  BMC Nephrology

Comparative effectiveness of cardiovascular outcomes in new users of sodium-glucose cotransporter-2 inhibitors: SGLT2 inhibitors in the real world

Richard J MacIsaac, Elif I Ekinci

Journal article  |  2017  |  Annals of Translational Medicine

The threat among us: significance and scale of diabetic chronic kidney disease in Australia

Ashani Lecamwasam, Elif I Ekinci, Richard J MacIsaac, Richard Saffery, Karen M Dwyer

Journal article  |  2017  |  Internal Medicine Journal

Bilirubin concentration is positively associated with haemoglobin concentration and inversely associated with albumin to creatinine ratio among Indigenous Australians: eGFR Study

JT Hughes, F Barzi, WE Hoy, GRD Jones, G Rathnayake, SW Majoni, MAB Thomas, A Sinha, A Cass, RJ MacIsaac, K O'Dea, LJ Maple-Brown

Journal article  |  2017  |  Clinical Biochemistry

Hyponatraemia and hypopituitarism: an easily missed entity

Melissa H Lee, Genevieve L Calder, Richard J MacIsaac, Nirupa Sachithanandan

Journal article  |  2017  |  Medical Journal of Australia

Assessing cutaneous microvascular function with iontophoresis: Avoiding non-specific vasodilation

Jordan Loader, Matthieu Roustit, Frances Taylor, Richard J MacIsaac, Simon Stewart, Christian Lorenzen, Guillaume Walther

Journal article  |  2017  |  Microvascular Research

Alcohol and recreational drug use in young adults with type 1 diabetes

Adam Pastor, Jennifer Conn, Jessie Teng, Casey L O'Brien, Margaret Loh, Lisa Collins, Richard MacIsaac, Yvonne Bonomo

Journal article  |  2017  |  Diabetes Research and Clinical Practice

Asymmetric changes in circulating insulin levels after an increase compared with a reduction in insulin pump basal rate in people with Type 1 diabetes

SA McAuley, GM Ward, JC Horsburgh, JL Gooley, AJ Jenkins, RJ MacIsaac, DN O'Neal

Journal article  |  2017  |  Diabetic Medicine

"It Is Definitely a Game Changer'': A Qualitative Study of Experiences with In-home Overnight Closed-Loop Technology Among Adults with Type 1 Diabetes

Christel Hendrieckx, Lucinda A Poole, Amin Sharifi, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Leon A Bach, Peter G Colman, Kavita Kumareswaran, Alicia J Jenkins, Richard J MacIsaac, Glenn M Ward, Benyamin Grosman, Anirban Roy, David N O'Neal, Jane Speight

Journal article  |  2017  |  Diabetes Technology & Therapeutics

Overnight Counter-Regulatory Hormone Levels and Next Day Glycemia in Adults with Type 1 Diabetes During Closed-Loop Insulin Delivery Versus Sensor-Augmented Pump with Low-Glucose Suspend

Anneke Graf, Glenn M Ward, Sara Vogrin, Vijaya Sundararajan, Amin Sharifi, Martin I De Bock, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Carolyn L Berthold, Nirubasini Paramalingam, Leon A Bach, Peter G Colman, Elizabeth A Davis, Benyamin Grosman, Alicia J Jenkins, Kavita Kumareswaran, Natalie Kurtz, Andrew Kyoong, Richard J MacIsaac, et al.

Journal article  |  2017  |  Diabetes Technology & Therapeutics

Closed-Loop Insulin Delivery for Adults with Type 1 Diabetes Undertaking High-Intensity Interval Exercise Versus Moderate-Intensity Exercise: A Randomized, Crossover Study

Dilshani C Jayawardene, Sybil A McAuley, Jodie C Horsburgh, Andre La Gerche, Alicia J Jenkins, Glenn M Ward, Richard J Maclsaac, Timothy J Roberts, Benyamin Grosman, Natalie Kurtz, Anirban Roy, David N O'Neal

Journal article  |  2017  |  Diabetes Technology & Therapeutics

Effects of glycaemic management on diabetic kidney disease

Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2017  |  World Journal of Diabetes

Comparison of creatinine and cystatin C based eGFR in the estimation of glomerular filtration rate in Indigenous Australians: The eGFR Study

Elizabeth LM Barr, Louise J Maple-Brown, Federica Barzi, Jaquelyne T Hughes, George Jerums, Elif I Ekinci, Andrew G Ellis, Graham RD Jones, Paul D Lawton, Cherian Sajiv, Sandawana W Majoni, Alex DH Brown, Wendy E Hoy, Kerin O'Dea, Alan Cass, Richard J MacIsaac

Journal article  |  2017  |  Clinical Biochemistry

Are the diagnoses of sarcopenia and diabetes associated with patients' progress in inpatient rehabilitation and how is this progress measured? A systematic literature review

Irina Churilov, Leonid Churilov, Richard MacIsaac, Elif Ilhan Ekinci

Conference Proceedings  |  2017  |  AUSTRALASIAN JOURNAL ON AGEING

Effectiveness of the cardiac-diabetes transcare program: protocol for a randomised controlled trial

Chiung-Jung Jo Wu, John J Atherton, Richard J MacIsaac, Mary Courtney, Anne M Chang, David R Thompson, Karam Kostner, Andrew I MacIsaac, Michael d'Emden, Nick Graves, Steven M McPhail

Journal article  |  2017  |  BMC Health Services Research

Aceruloplasminaemia: a disorder of diabetes and neurodegeneration

Genevieve L Calder, Melissa H Lee, Nirupa Sachithanandan, Sally Bell, Howard Zeimer, Richard J MacIsaac

Journal article  |  2017  |  Internal Medicine Journal

Clinical predictive factors in diabetic kidney disease progression

Nicholas J Radcliffe, Jas-Mine Seah, Michele Clarke, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2017  |  Journal of Diabetes Investigation

Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System Overnight Versus Sensor-Augmented Pump with Low-Glucose Suspend Function: A Randomized Crossover Study

Amin Sharifi, Martin I De Bock, Dilshani Jayawardene, Margaret M Loh, Jodie C Horsburgh, Carolyn L Berthold, Nirubasini Paramalingam, Leon A Bach, Peter G Colman, Elizabeth A Davis, Benyamin Grosman, Christel Hendrieckx, Alicia J Jenkins, Kavita Kumareswaran, Natalie Kurtz, Andrew Kyoong, Richard J MacIsaac, Jane Speight, Steven Trawley, Glenn M Ward, et al.

Journal article  |  2016  |  Diabetes Technology & Therapeutics

Decrease in serum potassium levels post saline suppression test in primary aldosteronism: an under-recognised phenomenon?

MH Lee, JE Moxey, MM Derbyshire, GM Ward, RJ Maclsaac, N Sachithanandan

Journal article  |  2016  |  Journal of Human Hypertension

A Prospective Study of Renal Transplant Recipients: A Fall in Insulin Secretion Underpins Dysglycemia After Renal Transplantation

David Langsford, Varuni Obeyesekere, Sara Vogrin, Jessie Teng, Richard J MacIsaac, Glenn Ward, Frank Alford, Karen M Dwyer

Journal article  |  2016  |  Transplantation Direct

Associations of serum adiponectin with markers of cardio-metabolic disease risk in Indigenous Australian adults with good health, diabetes and chronic kidney disease

JT Hughes, K O'Dea, K Piera, F Barzi, A Cass, WE Hoy, RJ Maclsaac, LJ Maple-Brown

Journal article  |  2016  |  Obesity Research & Clinical Practice

Does a single bout of resistance or aerobic exercise after insulin dose reduction modulate glycaemic control in type 2 diabetes? A randomised cross-over trial

Brett A Gordon, Stephen R Bird, Richard J MacIsaac, Amanda C Bensons

Journal article  |  2016  |  Journal of Science and Medicine in Sport

Cardio-renal protection with empagliflozin

Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2016  |  Journal of Translational Medicine

The Mental Health in Diabetes Service (MINDS) to enhance psychosocial health: study protocol for a randomized controlled trial

Casey L O'Brien, Chantal F Ski, David R Thompson, Gaye Moore, Serafino Mancuso, Alicia Jenkins, Glenn Ward, Richard J MacIsaac, Margaret Loh, Simon R Knowles, Susan L Rossell, David J Castle

Journal article  |  2016  |  Trials

Insulin pump basal adjustment for exercise in type 1 diabetes: a randomised crossover study

Sybil A McAuley, Jodie C Horsburgh, Glenn M Ward, Andre La Gerche, Judith L Gooley, Alicia J Jenkins, Richard J MacIsaac, David N O'Neal

Journal article  |  2016  |  Diabetologia

Cushing's conundrum: an unusual case of primary pigmented nodular adrenal disease in a 60-year-old woman

Jasna Aleksova, Glenn Ward, Kim Taubman, Jason Tan, Stephen Farrell, Stuart Galloway, Richard J MacIsaac, Nirupa Sachithanandan

Journal article  |  2016  |  The Lancet Diabetes & Endocrinology

A prospective study of renal transplant recipients: the interrelationship between insulin secretion and sensitivity underpins dysglycemia post following renal transplantation

Karen M Dwyer, David Langsford, Varuni Obeyesekere, Jessie Teng, Sara Vogrin, Richard MacIsaac, Glenn Ward, Frank Alford

Conference Proceedings  |  2016  |  TRANSPLANTATION

Progression of Kidney Disease in Indigenous Australians: The eGFR Follow-up Study

Louise J Maple-Brown, Jaquelyne T Hughes, Rebecca Ritte, Federica Barzi, Wendy E Hoy, Paul D Lawton, Graham RD Jones, Elizabeth Death, Alison Simmonds, Ashim K Sinha, Sajiv Cherian, Mark AB Thomas, Robyn McDermott, Alex DH Brown, Kerin O'Dea, George Jerums, Alan Cass, Richard J Maclsaac

Journal article  |  2016  |  Clinical Journal of the American Society of Nephrology

Feasibility of an Orthogonal Redundant Sensor incorporating Optical plus Redundant Electrochemical Glucose Sensing.

Sybil A McAuley, Tri T Dang, Jodie C Horsburgh, Anubhuti Bansal, Glenn M Ward, Sarkis Aroyan, Alicia J Jenkins, Richard J MacIsaac, Rajiv V Shah, David N O'Neal

Journal article  |  2016  |  Journal of Diabetes Science and Technology

BACKGROUND: Orthogonal redundancy for glucose sensing (multiple sensing elements utilizing distinct methodologies) may enhance per..

Redundancy in Glucose Sensing: Enhanced Accuracy and Reliability of an Electrochemical Redundant Sensor for Continuous Glucose Monitoring.

Amin Sharifi, Andrea Varsavsky, Johanna Ulloa, Jodie C Horsburgh, Sybil A McAuley, Balasubramanian Krishnamurthy, Alicia J Jenkins, Peter G Colman, Glenn M Ward, Richard J MacIsaac, Rajiv Shah, David N O'Neal

Journal article  |  2016  |  Journal of Diabetes Science and Technology

BACKGROUND: Current electrochemical glucose sensors use a single electrode. Multiple electrodes (redundancy) may enhance sensor pe..

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis

Melinda T Coughlan, Gavin C Higgins, Nguyen Tuong-Vi, Sally A Penfold, Vicki Thallas-Bonke, Sih Mm Tan, Georg Ramm, Nicole J Van Bergen, Darren C Henstridge, Karly C Sourris, Brooke E Harcourt, Ian A Trounce, Portia M Robb, Adrienne Laskowski, Sean L McGee, Amanda J Genders, Ken Walder, Brian G Drew, Paul Gregorevic, Hongwei Qian, et al.

Journal article  |  2016  |  Diabetes

Elevated baseline glomerular filtration rate (GFR) is independently associated with a more rapid decline in renal function of patients with type 1 diabetes

Hilary J Thomson, Elif I Ekinci, Nicholas J Radcliffe, Jas-mine Seah, Richard J MacIsaac, George Jerums, Erosha Premaratne

Journal article  |  2016  |  Journal of Diabetes and its Complications

Association of sex hormone-binding globulin and free testosterone with mortality in men with type 2 diabetes mellitus

Aye N Tint, Rudolf Hoermann, Henry Wong, Elif I Ekinci, Richard J MacIsaac, George Jerums, Jeffrey D Zajac, Mathis Grossmann

Journal article  |  2016  |  European Journal of Endocrinology

Estimating glomerular filtration rate: Performance of the CKD-EPI equation over time in patients with type 2 diabetes

Anna J Wood, Leonid Churilov, Nayomi Perera, David Thomas, Aurora Poon, Richard J MacIsaac, George Jerums, Elif I Ekinci

Journal article  |  2016  |  Journal of Diabetes and its Complications

The Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) equation does not improve the underestimation of Glomerular Filtration Rate (GFR) in people with diabetes and preserved renal function

Richard J MacIsaac, Elif I Ekinci, Erosha Premaratne, Zhong X Lu, Jas-mine Seah, Yue Li, Ray Boston, Glenn M Ward, George Jerums

Journal article  |  2015  |  BMC Nephrology

Hyperfiltration in Indigenous Australians with and without diabetes

Elif I Ekinci, Jaquelyne T Hughes, Mark D Chatfield, Paul D Lawton, Graham RD Jones, Andrew G Ellis, Alan Cass, Mark Thomas, Richard J MacIsaac, Kerin O'Dea, George Jerums, Louise J Maple-Brown

Journal article  |  2015  |  Nephrology Dialysis Transplantation

Short-term dietary salt supplementation blunts telmisartan induced increases in plasma renin activity in hypertensive patients with type 2 diabetes mellitus

Angela X Chen, George Jerums, Sara Baqar, Elisabeth Lambert, Goji Somarajah, Georgina Thomas, Christopher O'Callaghan, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2015  |  Clinical Science

Cardiovascular outcomes with antihypertensive therapy in type 2 diabetes: an analysis of intervention trials

G Jerums, S Panagiotopoulos, E Ekinci, RJ MacIsaac

Journal article  |  2015  |  Journal of Human Hypertension

The Association of Estimated Glomerular Filtration Rate With Diabetic Retinopathy and Macular Edema

Ryan Eyn Kidd Man, Muhammad Bayu Sasongko, Jie Jin Wang, Richard MacIsaac, Tien Yin Wong, Charumathi Sabanayagam, Ecosse L Lamoureux

Journal article  |  2015  |  Investigative Opthalmology & Visual Science

How does exercise affect kidney disease in T1DM?

George Jerums, Richard J MacIsaac

Journal article  |  2015  |  Nature Reviews Endocrinology

Deficiency in Apoptosis Inducing Factor Recapitulates Diabetic Nephropathy via Aberrant Mitochondrial Homeostasis

Melinda T Coughlan, Gavin C Higgins, Tuong-Vi Nguyen, Sally A Penfold, Vicki Thallas-Bonke, Sih Min Tan, Georg Ramm, Nicole J Van Bergen, Darren C Henstridge, Ian A Trounce, Karly C Sourris, Brooke E Harcourt, Portia M Robb, Adrienne Laskowski, Sean L Mcgee, Ken Walder, Paul Gregorevic, Hongwei Qian, Merlin C Thomas, Brian G Drew, et al.

Conference Proceedings  |  2015  |  DIABETES

Combining cutaneous silent periods with quantitative sudomotor axon reflex testing in the assessment of diabetic small fiber neuropathy

JT Kamel, SJ Vogrin, RJ Knight-Sadler, NK Willems, L Seiderer, MJ Cook, RJ MacIsaac, LJ Roberts

Journal article  |  2015  |  Clinical Neurophysiology

Untitled

Sally Abell, Howard Zeimer, Alvin Chong, Richard J MacIsaac

Journal article  |  2015  |  AUSTRALASIAN JOURNAL OF DERMATOLOGY

Adding Measures of Body Composition to the CKD-EPI GFR Estimating Equation in Indigenous Australians: The eGFR Study

Louise J Maple-Brown, Jaquelyne T Hughes, Mark D Chatfield, Leigh C Ward, Leonard S Piers, Graham RD Jones, Paul D Lawton, Andrew G Ellis, Alan Cass, Wendy E Hoy, Kerin O'Dea, Richard J MacIsaac, George Jerums

Journal article  |  2015  |  American Journal of Kidney Diseases

The impact of hyperfiltration on the diabetic kidney

E Premaratne, S Verma, EI Ekinci, G Theverkalam, G Jerums, RJ MacIsaac

Journal article  |  2015  |  Diabetes & Metabolism

The shifting paradigm of albuminuria in diabetic kidney disease

AK Watts, KM Dwyer, EI Ekinci, G Jerums, RJ MacIsaac

Journal article  |  2015  |  Medicine Today

Prolonged life-threatening hypoglycaemia following dose escalation of octreotide LAR in a patient with malignant polysecreting pancreatic neuroendocrine tumour

Sally K Abell, Jessie Teng, Anthony Dowling, Michael S Hofman, Richard J MacIsaac, Nirupa Sachithanandan

Journal article  |  2015  |  Endocrinology, Diabetes & Metabolism Case Reports

Protracted hypocalcaemia following a single dose of denosumab in humoral hypercalcaemia of malignancy due to PTHrP-secreting neuroendocrine tumour

Jessie Teng, Sally Abell, Rodney J Hicks, Michael S Hofman, Nirupa Sachithanandan, Penny McKelvie, Richard J MacIsaac

Journal article  |  2014  |  Clinical Endocrinology

New Treatments for Type 2 Diabetes: Cardiovascular Protection Beyond Glucose Lowering?

Dilshani Jayawardene, Glenn M Ward, David N O'Neal, Geetha Theverkalam, Andrew I MacIsaac, Richard J MacIsaac

Journal article  |  2014  |  Heart, Lung and Circulation

The high burden of inpatient diabetes mellitus: the Melbourne Public Hospitals Diabetes Inpatient Audit

Leon A Bach, Elif I Ekinci, Dennis Engler, Chris Gilfillan, P Shane Hamblin, Richard J MacIssac, Georgia Soldatos, Cheryl Steele, Glenn M Ward, Sue Wyatt

Journal article  |  2014  |  Medical Journal of Australia

Spectrum of renal disease in diabetes

Jessie Teng, Karen M Dwyer, Prue Hill, Emily See, Elif I Ekinci, George Jerums, Richard J Macisaac

Journal article  |  2014  |  Nephrology

Serum vitamin D levels, diabetes and cardio-metabolic risk factors in Aboriginal and Torres Strait Islander Australians

Louise J Maple-Brown, Jaquelyne T Hughes, Zhong X Lu, Kanakamani Jeyaraman, Paul Lawton, Graham RD Jones, Andrew Ellis, Ashim Sinha, Alan Cass, Richard J MacIsaac, George Jerums, Kerin O'Dea

Journal article  |  2014  |  Diabetology & Metabolic Syndrome

Performance of formulas for estimating glomerular filtration rate in Indigenous Australians with and without Type 2 diabetes: the eGFR Study

LJ Maple-Brown, EI Ekinci, JT Hughes, M Chatfield, PD Lawton, GRD Jones, AG Ellis, A Sinha, A Cass, WE Hoy, K O'Dea, G Jerums, RJ MacIsaac

Journal article  |  2014  |  Diabetic Medicine

Symptomatic Pneumocephalus After Trans-sphenoidal Surgery

Jessie Teng, Richard J MacIsaac, Yi Yuen Wang

Journal article  |  2014  |  The Journal of Clinical Endocrinology & Metabolism

'Progressive diabetic nephropathy. How useful is microalbuminuria?: Contra'

Richard J Maclsaac, Elif I Ekinci, G Jerums

Journal article  |  2014  |  Kidney International

Predicting renal function decline in patients with T2DM

George Jerums, Richard J MacIsaac

Journal article  |  2014  |  Nature Reviews Endocrinology

Relationship Between Urinary Sodium Excretion Over Time and Mortality in Type 2 Diabetes

Elif I Ekinci, John L Moran, Merlin C Thomas, Karey Cheong, Sophie Clarke, Angela Chen, Matt Dobson, Amanda Leong, Richard J MacIsaac, George Jerums

Journal article  |  2014  |  Diabetes Care

Markers of and Risk Factors for the Development and Progression of Diabetic Kidney Disease

Richard J MacIsaac, Elif I Ekinci, George Jerums

Journal article  |  2014  |  American Journal of Kidney Diseases

Prevalence, predictors and evolution of echocardiographically defined cardiac abnormalities in adults with type 1 diabetes: an observational cohort study

Bryan Wai, Sheila K Patel, Michelle Ord, Richard J MacIsaac, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2014  |  Journal of Diabetes and its Complications

Relationship between urinary sodium excretion and serum aldosterone in patients with diabetes in the presence and absence of modifiers of the renin-.a ngiotensin-aldosterone system

Renata Libianto, George Jerums, Que Lam, Angela Chen, Sara Baqar, Felicity Pyrlis, Richard J Macisaac, John Moran, Elif I Ekinci

Journal article  |  2014  |  Clinical Science

Reducing the complications of type 2 diabetes: Challenges in individualising care

JM Seah, H Yao, RJ MacIsaac, EI Ekinci, G Jerums

Journal article  |  2014  |  Medicine Today

Renal Structure in Normoalbuminuric and Albuminuric Patients With Type 2 Diabetes and Impaired Renal Function

Elif I Ekinci, George Jerums, Alison Skene, Paul Crammer, David Power, Karey Y Cheong, Sianna Panagiotopoulos, Karen McNeil, Scott T Baker, Paola Fioretto, Richard J MacIsaac

Journal article  |  2013  |  Diabetes Care

Glycemic response varies between resistance and aerobic exercise in inactive males with long-term type 2 diabetes

Brett A Gordon, Stephen R Bird, Richard J MacIsaac, Amanda C Benson

Journal article  |  2013  |  Applied Physiology, Nutrition and Metabolism

Development of a novel polyclonal antibody-based immunoassay for the quantitation of non-albumin urinary proteins

WB Haigh, DM Guralski, LM Arrigo, JT Letsinger, M Clarke, RJ MacIsaac, G Jerums, DL Very

Journal article  |  2013  |  The Open Clinical Chemistry Journal

Background: Better diagnostic methods to detect urinary proteinuria or albuminuria, important indicators of di..

Urinary Proteomics for Early Diagnosis in Diabetic Nephropathy

Petra Zuerbig, George Jerums, Peter Hovind, Richard J MacIsaac, Harald Mischak, Stine E Nielsen, Sianna Panagiotopoulos, Frederic Persson, Peter Rossing

Journal article  |  2012  |  Diabetes

Early glomerular filtration rate loss as a marker of diabetic nephropathy

G Jerums, E Ekinci, S Panagiotopoulos, RJ MacIsaac

Journal article  |  2012  |  European Endocrinology

In the early 1980s, studies in type 1 diabetes suggested that glomerular filtration rate (GFR) loss begins with the onset of macro..

Accurate Assessment of Kidney Function in Indigenous Australians: The Estimated GFR Study

Louise J Maple-Brown, Jaquelyne T Hughes, Paul D Lawton, Graham RD Jones, Andrew G Ellis, Katrina Drabsch, Alex DH Brown, Alan Cass, Wendy E Hoy, Richard J MacIsaac, Kerin O'Dea, George Jerums

Journal article  |  2012  |  American Journal of Kidney Diseases

Chronic kidney disease and measurement of albuminuria or proteinuria: a position statement

David W Johnson, Graham RD Jones, Timothy H Mathew, Marie J Ludlow, Stephen J Chadban, Tim Usherwood, Kevan Polkinghorne, Stephen Colagiuri, George Jerums, Richard MacIsaac, Helen Martin

Journal article  |  2012  |  MEDICAL JOURNAL OF AUSTRALIA

ACCURATE ASSESSMENT OF KIDNEY FUNCTION IN INDIGENOUS AUSTRALIANS: THE EGFR STUDY

LJ Maple-Brown, JT Hughes, PD Lawton, GRD Jones, AG Ellis, K Drabsch, A Cass, WE Hoy, RJ Macisaac, K O'Dea, G Jerums

Conference Proceedings  |  2012  |  NEPHROLOGY

Hypothyroidism Investigation and management

Michelle So, Richard J MacIsaac, Mathis Grossmann

Journal article  |  2012  |  Australian Family Physician

Early glomerular filtration rate loss as a marker of diabetic nephropathy

G Jerums, E Ekinci, S Panagiotopoulos, RJ MacIsaac

Journal article  |  2012  |  US endocrinology

In the early 1980s, studies in type 1 diabetes suggested that glomerular filtration rate (GFR) loss begins with the onset of macro..

The CTGF gene-945 G/C polymorphism is not associated with cardiac or kidney complications in subjects with type 2 diabetes

Sheila K Patel, Bryan Wai, Richard J MacIsaac, Sharon Grant, Elena Velkoska, Michelle Ord, Sianna Panagiotopoulos, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2012  |  Cardiovascular Diabetology

Diabetic Chronic Kidney Disease

RJ Macisaac, G Jerums, GF Watts

Book Chapter  |  2012

Hypocalcemia induced by raloxifene.

Thuy DT Vu, Suresh Varadarajan, Ego Seeman, George Jerums, Richard J MacIsaac

Journal article  |  2012  |  Current Drug Safety

Raloxifene is an anti-resorptive agent used in postmenopausal osteoporosis. This is the first report of the occurrence of clinical..

Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes

Sheila K Patel, Bryan Wai, Michelle Ord, Richard J MacIsaac, Sharon Grant, Elena Velkoska, Sianna Panagiotopoulos, George Jerums, Piyush M Srivastava, Louise M Burrell

Journal article  |  2012  |  American Journal of Hypertension

Early Glomerular Filtration Rate Loss as a Marker of Diabetic Nephropathy

G Jerums, EI Ekinci, S Panagiotopoulos, RJ Macisaac

Journal article  |  2012  |  European Nephrology

Estimating glomerular filtration rate in diabetes using serum cystatin C

RJ MacIsaac, E Premaratne, G Jerums

Journal article  |  2011  |  Clinical Biochemist Reviews

Intensive Glucose Control and Cardiovascular Outcomes in Type 2 Diabetes

Richard J MacIsaac, George Jerums

Journal article  |  2011  |  Heart, Lung and Circulation

New approaches for the evaluation of renal vascular function in diabetes

G Jerums, RJ MacIsaac

Journal article  |  2011  |  Diabetologia

Failure of functional imaging with gallium-68-DOTA-D-Phe1-Tyr3-octreotide positron emission tomography to localize the site of ectopic adrenocorticotropic hormone secretion: a case report.

Linsey U Gani, Emily J Gianatti, Ada S Cheung, George Jerums, Richard J Macisaac

Journal article  |  2011  |  Journal of Medical Case Reports

INTRODUCTION: The diagnostic efficacy of biochemical and imaging modalities for investigating the causes of Cushing's syndrome are..

Response to Comment on: Ekinci et al. Dietary Salt Intake and Mortality in Patients With Type 2 Diabetes. Diabetes Care 2011;34:703–709.

Elif I Ekinci, Richard J MacIsaac, Merlin C Thomas, George Jerums

Journal article  |  2011  |  Diabetes Care

Diabetic kidney disease with and without albuminuria

Richard J MacIsaac, George Jerums

Journal article  |  2011  |  Current Opinion in Nephrology and Hypertension

Dietary Salt Intake and Mortality in Patients With Type 2 Diabetes

Elif I Ekinci, Sophie Clarke, Merlin C Thomas, John L Moran, Karey Cheong, Richard J MacIsaac, George Jerums

Journal article  |  2011  |  Diabetes Care

Advanced Glycation Urinary Protein-Bound Biomarkers and Severity of Diabetic Nephropathy in Man

Melinda T Coughlan, Sheila K Patel, George Jerums, Sally A Penfold, Nguyen Tuong-Vi, Karly C Sourris, Sianna Panagiotopoulos, Piyush M Srivastava, Mark E Cooper, Louise M Burrell, Richard J MacIsaac, Josephine M Forbes

Journal article  |  2011  |  American Journal of Nephrology

High sodium and low potassium intake in patients with Type 2 diabetes

EI Ekinci, KY Cheong, M Dobson, E Premaratne, S Finch, RJ MacIsaac, G Jerums

Journal article  |  2010  |  Diabetic Medicine

The clinical significance of hyperfiltration in diabetes

G Jerums, E Premaratne, S Panagiotopoulos, RJ MacIsaac

Journal article  |  2010  |  Diabetologia

Type 2 diabetes Controlling hyperglycaemia with early insulin use

Richard MacIsaac, Ada Cheung, George Jerums

Journal article  |  2010  |  Australian Family Physician

Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy

Sally A Penfold, Melinda T Coughlan, Sheila K Patel, Piyush M Srivastava, Karly C Sourris, David Steer, Diane E Webster, Merlin C Thomas, Richard J MacIsaac, George Jerums, Louise M Burrell, Mark E Cooper, Josephine M Forbes

Journal article  |  2010  |  Kidney International

Salt supplementation blunts the blood pressure response to telmisartan with or without hydrochlorothiazide in hypertensive patients with type 2 diabetes

EI Ekinci, G Thomas, RJ MacIsaac, C Johnson, C Houlihan, S Panagiotopoulos, E Premaratne, H Hao, S Finch, C O'Callaghan, G Jerums

Journal article  |  2010  |  Diabetologia

Prevention and management of chronic kidney disease in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Cost-effectiveness and socioeconomic implications of prevention and management of chronic kidney disease in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Assessment of kidney function in type 2 diabetes

S Chadban, M Howell, S Twigg, M Thomas, G Jerums, A Cass, D Campbell, K Nicholls, A Tong, G Mangos, A Stack, RJ MacIsaac, S Girgis, R Colagiuri, S Colagiuri, J Craig

Journal article  |  2010  |  Nephrology

Study Protocol - Accurate assessment of kidney function in Indigenous Australians: aims and methods of the eGFR Study

Louise J Maple-Brown, Paul D Lawton, Jaquelyne T Hughes, Suresh K Sharma, Graham RD Jones, Andrew G Ellis, Wendy Hoy, Alan Cass, Richard J MacIsaac, Ashim K Sinha, Mark AB Thomas, Leonard S Piers, Leigh C Ward, Katrina Drabsch, Sianna Panagiotopoulos, Robyn McDermott, Kevin Warr, Sajiv Cherian, Alex Brown, George Jerums, et al.

Journal article  |  2010  |  BMC Public Health

Type 2 diabetes Controlling hyperglycaemia in type 2 diabetes by the early use of insulin

RJM Macisaac, A Cheung, GJ Jerums

Journal article  |  2010  |  Australian Family Physician

Erratum: Patterns of glycaemic control in Australian primary care (NEFRON 8). (Internal Medicine Journal (2009) 39 (512-518))

RJ MacIsaac, G Jerums, AJ Weekes, MC Thomas

Journal article  |  2009  |  Internal Medicine Journal

Nonalbuminuric Renal Impairment in Type 2 Diabetic Patients and in the General Population (National Evaluation of the Frequency of Renal Impairment cO-existing with NIDDM [NEFRON] 11)

Merlin C Thomas, Richard J MacIsaac, George Jerums, Andrew Weekes, John Moran, Jonathan E Shaw, Robert C Atkins

Journal article  |  2009  |  Diabetes Care

Effects of Salt Supplementation on the Albuminuric Response to Telmisartan With or Without Hydrochlorothiazide Therapy in Hypertensive Patients With Type 2 Diabetes Are Modulated by Habitual Dietary Salt Intake

Elif I Ekinci, Georgina Thomas, David Thomas, Cameron Johnson, Richard J MacIsaac, Christine A Houlihan, Sue Finch, Sianna Panagiotopoulos, Chris O'Callaghan, George Jerums

Journal article  |  2009  |  Diabetes Care

Patterns of glycaemic control in Australian primary care (NEFRON 8)

RJ MacIsaac, G Jerums, AJ Weekes, MC Thomas

Journal article  |  2009  |  Internal Medicine Journal

Blood pressure lowering and outcomes in type 2 diabetes: Implications of the blood pressure-lowering arm of the advance trial

RJ MacIsaac, D Barit, G Jerums

Journal article  |  2009  |  Current Hypertension Reviews

Integrating albuminuria and GFR in the assessment of diabetic nephropathy

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, Richard J MacIsaac

Journal article  |  2009  |  Nature Reviews Nephrology

Low testosterone and anaemia in men with type 2 diabetes

Mathis Grossmann, Sianna Panagiotopolous, Ken Sharpe, Richard J MacIsaac, Sophie Clarke, Jeffrey D Zajac, George Jerums, Merlin C Thomas

Journal article  |  2009  |  Clinical Endocrinology

Cost-effectiveness of multipronged agressive management vs standard care in type 2 diabetes

R MACISAAC, G JERUMS

Journal article  |  2009  |  Diabetes Management Journal

Insulin e-Learning module an effective means of education delivery to hospital health professionals?

L Ho, TP To, R MacIsaac

Journal article  |  2009  |  Journal of Pharmacy Practice and Research

New and old markers of progression of diabetic nephropathy

G Jerums, E Premaratne, S Panagiotopoulos, S Clarke, DA Power, RJ MacIsaac

Journal article  |  2008  |  Diabetes Research and Clinical Practice

The significance of glycaemic control in reducing cardio events

RJ Macisaac

Journal article  |  2008  |  Australian Journal of Pharmacy

Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes

Richard J MacIsaac, Merlin C Thomas, Sianna Panagiotopoulos, Trudy J Smith, Huming Hao, D Geoffrey Matthews, George Jerums, Louise M Burrell, Piyush M Srivastava

Journal article  |  2008  |  Cardiovascular Diabetology

Low testosterone levels are common and associated with insulin resistance in men with diabetes

Mathis Grossmann, Merlin C Thomas, Sianna Panagiotopoulos, Ken Sharpe, Richard J MacIsaac, Sophie Clarke, Jeffrey D Zajac, George Jerums

Journal article  |  2008  |  Journal of Clinical Endocrinology and Metabolism

Serial measurements of cystatin C are more accurate than creatinine-based methods in detecting declining renal function in type 1 diabetes

Erosha Premaratne, Richard J Macisaac, Sue Finch, Sianna Panagiotopoulos, Elif Ekinci, George Jerums

Journal article  |  2008  |  Diabetes Care

Low Testosterone Levels Are Common and Associated with Insulin Resistance in Men with Diabetes

Mathis Grossmann, Merlin C Thomas, Sianna Panagiotopoulos, Ken Sharpe, Richard J MacIsaac, Sophie Clarke, Jeffrey D Zajac, George Jerums

Journal article  |  2008  |  Journal of Clinical Endocrinology & Metabolism

Outcomes for general medical inpatients with diabetes mellitus and new hyperglycaemia

Scott T Baker, Cherie Y Chiang, Jeffrey D Zajac, Leon A Bach, George Jerums, Richard J Maclsaac

Journal article  |  2008  |  Medical Journal of Australia

Prevalence and predictors of cardiac hypertrophy and dysfunction in patients with Type 2 diabetes

Piyush M Srivastava, Paul Calafiore, Richard J Macisaac, Sheila K Patel, Merlin C Thomas, George Jerums, Louise M Burrell

Journal article  |  2008  |  Clinical Science

Lowering of Proteinuria in Response to Antihypertensive Therapy Predicts Improved Renal Function in Late but Not in Early Diabetic Nephropathy: A Pooled Analysis

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, David A Power, Richard J MacIsaac

Journal article  |  2008  |  American Journal of Nephrology

Lowering of proteinuria in response to antihypertensive therapy predicts improved renal function in late but not in early diabetic nephropathy: A pooled analysis

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, David A Power, Richard J Maclsaac

Journal article  |  2008  |  American Journal of Nephrology

The accuracy of cystatin C and commonly used creatinine-based methods for detecting moderate and mild chronic kidney disease in diabetes

RJ MacIsaac, C Tsalamandris, MC Thomas, E Premaratne, S Panagiotopoulos, TJ Smith, A Poon, MA Jenkins, SI Ratnaike, DA Power, G Jerums

Journal article  |  2007  |  Diabetic Medicine

Management of Acute Illness in Adults with Type 1 Diabetes

R MACISAAC, G JERUMS

Journal article  |  2007  |  Diabetes Management

Measuring renal function in subjects with diabetes

R MACISAAC, G JERUMS

Journal article  |  2007  |  Clinical Chemistry and Laboratory Medicine

The epidemiology of hemoglobin levels in patients with type 2 diabetes

Merlin C Thomas, Con Tsalamandris, Richard J Maclsaac, George Jerums

Journal article  |  2006  |  American Journal of Kidney Diseases

Optimizing heart failure management: An Australian experience

Peter Barlis, Richard MacIsaac, David L Hare, Louise M Burrell

Journal article  |  2006  |  International Journal of Cardiology

Optimizing heart failure management: An Australian experience

Peter Barlis, Richard MacIsaac, David L Hare, Louise M Burrell

Journal article  |  2006  |  International Journal of Cardiology

Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease?

Richard J MacIsaac, Sianna Panagiotopoulos, Karen J McNeil, Trudy J Smith, Con Tsalamandris, Huming Hao, P Geoffrey Matthews, Merlin C Thomas, David A Power, George Jerums

Journal article  |  2006  |  Diabetes Care

Estimating glomerular filtration rate in diabetes: a comparison of cystatin-C- and creatinine-based methods

RJ MacIsaac, C Tsalamandris, MC Thomas, E Premaratne, S Panagiotopoulos, TJ Smith, A Poon, MA Jenkins, SI Ratnaike, DA Power, G Jerums

Journal article  |  2006  |  Diabetologia

Estimating glomerular filtration rate in diabetes: a comparison of cystatin-C- and creatinine-based methods

RJ MacIsaac, C Tsalamandris, MC Thomas, E Premaratne, S Panagiotopoulos, TJ Smith, A Poon, MA Jenkins, SI Ratnaike, DA Power, G Jerums

Journal article  |  2006  |  Diabetologia

Is nonalbuminuric renal insufficiency in type 2 diabetes related to an increase in intrarenal vascular disease?

Richard J MacIsaac, Sianna Panagiotopoulos, Karen J McNeil, Trudy J Smith, Con Tsalamandris, Huming Hao, P Geoffrey Matthews, Merlin C Thomas, David A Power, George Jerums

Journal article  |  2006  |  Diabetes Care

OBJECTIVE: To investigate the role of intrarenal vascular disease in the pathogenesis of nonalbuminuric renal insufficiency in typ..

Diabetes and the Kidney

RJ Macisaac, GF Watts

Book Chapter  |  2006

Functional erythropoietin deficiency in patients with Type 2 diabetes and anaemia

MC Thomas, C Tsalamandris, R MacIsaac, G Jerums

Journal article  |  2006  |  Diabetic Medicine

Anemia and Diabetic Nephropathy

G JERUMS, R MACISAAC, S PANAGIOTOPOULOS, undefined thomas

Book Chapter  |  2006

Podocytes and Diabetic Nephropathy

G JERUMS, S PANAGIOTOPOULOS, R MACISAAC

Book Chapter  |  2006

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

Piyush M Srivastava, Merlin C Thomas, Paul Calafiore, Richard J MacIsaac, George Jerums, Louise M Burrell

Journal article  |  2006  |  Clinical Science

Anaemia is common in patients with diabetes and associated with an increased risk of diabetic complications. Although the role of ..

Pathogenesis of Nephropathy

G JERUMS, R MACISAAC

Journal article  |  2006  |  Diabetes Management Journal

Diastolic dysfunction is associated with anaemia in patients with Type II diabetes

PM Sristava, MC Thomas, P Calafiore, RJ MacIsaac, G Jerums, LM Burrell

Journal article  |  2006  |  Clinical Science

A case of mucormycosis limited to the parotid gland

A Chandu, RJ MacIsaac, DP MacGregor, MC Campbell, MJ Wilson, LA Bach

Journal article  |  2005  |  Head & Neck

Renal hyperfiltration in type 2 diabetes: effect of age-related decline in glomerular filtration rate

E Premaratne, RJ MacIsaac, C Tsalamandris, S Panagiotopoulos, T Smith, G Jerums

Journal article  |  2005  |  Diabetologia

Albuminuric and non-albuminuric pathways to renal impairment in diabetes.

RJ Macisaac, G Jerums

Journal article  |  2005  |  Minerva Endocrinologica

Traditionally, microvascular disease resulting in a glomerulopathy and an increase in albumin excretion rate (AER) is believed to ..

Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes

MC Thomas, G Jerums, C Tsalamandris, R MacIsaac, S Panagiotopoulos, ME Cooper

Journal article  |  2005  |  Kidney International

Anemia with impaired erythropoietin response in diabetic patients

MC Thomas, ME Cooper, C Tsalamandris, R MacIsaac, G Jerums

Journal article  |  2005  |  Archives of Internal Medicine

Anaemia in diabetes: an emerging complication of microvascular disease.

Merlin Thomas, Con Tsalamandris, Richard MacIsaac, George Jerums

Journal article  |  2005  |  Current Diabetes Reviews

Diabetes as the dominant cause of ESRD is also the major cause of renal anaemia. However, most patients with diabetic kidney disea..

How long before I will need dialysis?

G JERUMS, S PANAGIOTOPOULOS, R MACISAAC

Conference Proceedings  |  2005  |  International Diabetes Federation

Low-molecular weight advanced glycation end products: Markers of tissue AGE accumulation and more?

MC Thomas, JM Forbes, R MacIsaac, G Jerums, ME Cooper

Journal article  |  2005  |  Annals of The New York Academy of Sciences

Low-molecular-weight AGEs are associated with GFR and anemia in patients with type 2 diabetes

MC Thomas, C Tsalamandris, R MacIsaac, T Medley, B Kingwell, ME Cooper, G Jerums

Journal article  |  2004  |  Kidney International

Anemia in patients with type 1 diabetes

MC Thomas, RJ MacIsaac, C Tsalamandris, L Molyneaux, I Goubina, G Fulcher, D Yue, G Jerums

Journal article  |  2004  |  Journal of Clinical Endocrinology & Metabolism

Thiazolidinediones and congestive heart failure - exacerbation or new onset of left ventricular dysfunction?

PM Srivastava, P Calafiore, RJ MacIsaac, DL Hare, G Jerums, LM Burrell

Journal article  |  2004  |  Diabetic Medicine

Elevated iron indices in patients with diabetes

MC Thomas, RJ MacIsaac, C Tsalamandris, G Jerums

Journal article  |  2004  |  Diabetic Medicine

The burden of anaemia in type 2 diabetes and the role of nephropathy: a cross-sectional audit

MC Thomas, RJ MacIsaac, C Tsalamandris, L Molyneaux, I Goubina, G Fulcher, D Yue, G Jerums

Journal article  |  2004  |  Nephrology, Dialysis, Transplantation

High prevalence of immunounreactive albumin in urine from diabetic patients with a low glomerular filtration rate and normoalbuminuria

TM Osicka, RJ MacIsaac, G Jerums, WD Comper

Journal article  |  2004  |  Diabetes Care

High Prevalence of Immunounreactive Albumin in Urine From Diabetic Patients With a Low Glomerular Filtration Rate and Normoalbuminuria

TM Osicka, RJ MacIsaac, G Jerums, WD Comper

Journal article  |  2004  |  Diabetes Care

Clinical indications of thiazolidinediones

RJ MacIsaac, G Jerums

Journal article  |  2004  |  Australian Prescriber

Earlier detection of micro albuminuria in diabetic patients using a new urinary albumin assay

WD Comper, TM Osicka, M Clark, RJ MacIsaac, G Jerums

Journal article  |  2004  |  Kidney International

New insights into the significance of microalbuminuria

RJ Maclsaac, G Jerums, ME Cooper

Journal article  |  2004  |  Current Opinion in Nephrology and Hypertension

Microalbuminuria and GFR in type 1 and type 2 diabetes

G JERUMS, S PANAGIOTOPOULOS, RJ MACISAAC

Book Chapter  |  2004

Nonalbuminuric renal insufficiency in type 2 diabetes

R MacIsaac, C Tsalamandris, S Panagiotopoulos, T Smith, K McNeil, G Jerums

Journal article  |  2004  |  Diabetes Care

Microalbuminuria and diabetic cardiovascular disease.

Richard J MacIsaac, Mark E Cooper

Journal article  |  2003  |  Current Atherosclerosis Reports

Unrecognized anemia in patients with diabetes - A cross-sectional survey

MC Thomas, R MacIsaac, C Tsalamandris, D Power, G Jerums

Journal article  |  2003  |  Diabetes Care

Diabetes and dysbetalipoproteinaemia

JD BEST, M YEO, RJ MACISAAC

Book Chapter  |  2003

Diabetic nephropathy: epidemiology and clinical description

G JERUMS, S PANAGIOTOPOULOS, RJ MACISAAC

Book Chapter  |  2003

Mixed diabetic ketoacidosis and hyperosmolarity

RJ MACISAAC, G JERUMS

Book Chapter  |  2003

Seizures after alendronate

RJ Maclsaac, E Seeman, G Jerums

Journal article  |  2002  |  JRSM

Diabetic muscle infarction

RJ MacIsaac, G Jerums, L Scurrah

Journal article  |  2002  |  Medical Journal of Australia

Influence of age on the presentation and outcome of acidotic and hyperosmolar diabetic emergencies

RJ MacIsaac, LY Lee, KJ McNeil, C Tsalamandris, G Jerums

Journal article  |  2002  |  Internal Medicine Journal

Diabetic ketoacidosis secondary to dento-alveolar infection

A Chandu, RJ MacIsaac, ACH Smith, LA Bach

Journal article  |  2002  |  International Journal of Oral and Maxillofacial Surgery

Treatment of dyslipidaemia in the elderly

RJ MacIsaac, G Jerums

Journal article  |  2002  |  Journal of Pharmacy Practice and Research

Diabetic muscle infarction

RJ MACISAAC, G JERUMS, L SCURRAH

Journal article  |  2002  |  Medical Journal of Australia

Treatment of microalbuminuria in patients with type 2 diabetes mellitus.

George Jerums, Richard J MacIsaac

Journal article  |  2002  |  Treatments in Endocrinology

The incidence of type 2 diabetes mellitus is increasing world-wide, and is now one of the leading causes of end-stage renal diseas..

Effect of arginine vasopressin and parathyroid hormone-related protein on renal function in the ovine foetus.

RS Horne, RJ MacIsaac, KM Moritz, K Tangalakis, EM Wintour

Journal article  |  1993  |  Clinical and Experimental Pharmacology and Physiology

1. The effects of intravenous infusions of arginine vasopressin (AVP), parathyroid hormone-related protein (PTHrP) and AVP+PTHrP o..

Effects of thyroparathyroidectomy, parathyroid hormone, and PTHrP on kidneys of ovine fetuses

RJ MacIsaac, RSC Horne, IW Caple, TJ Martin, EM Wintour

Journal article  |  1993  |  American Journal of Physiology - Endocrinology and Metabolism

ONTOGENY OF PARATHYROID HORMONE-RELATED PROTEIN IN THE OVINE PARATHYROID-GLAND

RJ MACISAAC, IW CAPLE, JA DANKS, H DIEFENBACHJAGGER, V GRILL, JM MOSELEY, J SOUTHBY, TJ MARTIN

Journal article  |  1991  |  Endocrinology

Premature birth of live lambs induced by pulsatile infusion of ACTH.

RJ MacIsaac, RS Carson, AP Horvath, EM Wintour

Journal article  |  1990  |  Journal of Endocrinology

This study was designed to investigate the effects of pulsatile infusion of ACTH into ovine fetuses on the endocrine changes that ..

The roles of the parathyroid glands, parathyroid hormone (PTH), parathyroid hormone-related protein (PTHrP), and elevated plasma calcium in bone formation in fetal lambs

IW Caple, JA Heath, TT Pham, RJ MacIsaac, CP Rodda, W Farrugia, JD Wark, AD Care, TJ Martin

Conference Proceedings  |  1990  |  Calcium regulation and bone metabolism. Basic and clinical aspects: proceedings of the 10th International Conference on calcium regulating hormones and bone metabolism. ICS886

In vivo regulation of adrenocorticotrophin secretion in the immature ovine fetus. Modulation by ovine corticotrophin releasing hormone and arginine vasopressin.

RJ MacIsaac, M Congiu, M Levidiotis, JG McDougall, EM Wintour

Journal article  |  1989  |  Journal of Developmental Physiology

This study investigates the in vivo regulation of ACTH secretion in the immature ovine fetus by AVP and oCRH. Previously we have d..

Cortisol feedback on ovine fetal ACTH secretion during the last fifth of gestation.

RJ MacIsaac, JG McDougall, EM Wintour

Journal article  |  1989  |  Reproduction, Fertility and Development

This study investigates the development of the feedback relationship between cortisol and ACTH in ovine fetuses at 117-119 (n = 5)..

Effect of hormone-induced premature parturition on hemoglobin switching in sheep.

A Horvath, A Butkus, RJ MacIsaac, L Pontefract, EM Wintour

Journal article  |  1988  |  Pediatric Research

This study examines the effect of premature delivery on the switch from fetal (alpha 2 tau 2) to adult (alpha 2 beta 2) Hb, in lam..

The role of the fetal adrenal in hemoglobin switching in sheep.

EM Wintour, J Haralambidis, A Horvath, RJ MacIsaac, JD Penschow, L Pontefract

Journal article  |  1987  |  Progress in clinical and biological research

Effect of long-term infusion of ovine corticotrophin-releasing factor in the immature ovine fetus.

EM Wintour, RJ Bell, RS Carson, RJ MacIsaac, GW Tregear, W Vale, XM Wang

Journal article  |  1986  |  Journal of Endocrinology

Synthetic ovine corticotrophin-releasing factor (oCRF) was infused continuously into the jugular veins of six ovine fetuses for 5-..

The value of urine osmolality as an index of stress in the ovine fetus.

EM Wintour, RJ Bell, M Congui, RJ MacIsaac, X Wang

Journal article  |  1985  |  Journal of Developmental Physiology

In ovine fetuses, during 100-130 days of gestation, urine osmolalities less than 175 mosmol/kg water were associated with plasma i..

Development of the hypothalamic-pituitary-axis in the ovine fetus: ontogeny of action of ovine corticotropin-releasing factor.

RJ MacIsaac, RJ Bell, JG McDougall, GW Tregear, X Wang, EM Wintour

Journal article  |  1985  |  Journal of Developmental Physiology

In samples from twenty chronically cannulated ovine fetuses the plasma immunoreactive adrenocorticotrophin (ACTH) concentrations w..

New Treatments for Diabetic Chronic Kidney Disease

Richard J MacIsaac

Journal article  |  Journal of Nephrology & Therapeutics