Nada Slakeski

The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis

Hong Min Ng, Nada Slakeski, Catherine A Butler, Paul D Veith, Yu-Yen Chen, Sze Wei Liu, Brigitte Hoffmann, Stuart G Dashper, Eric C Reynolds

Journal article  |  2019  |  Frontiers in Cellular and Infection Microbiology

A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis

Neil M O'Brien-Simpson, James A Holden, Jason C Lenzo, Yan Tan, Gail C Brammar, Katrina A Walsh, William Singleton, Rebecca KH Orth, Nada Slakeski, Keith J Cross, Ivan B Darby, Dorit Becher, Tony Rowe, Adriana Baz Morelli, Andrew Hammet, Andrew Nash, Anna Brown, Bing Ma, Didier Vingadassalom, Jacqueline McCluskey, et al.

Journal article  |  2016  |  npj Vaccines

PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System

Jacqueline E Heath, Christine A Seers, Paul D Veith, Catherine A Butler, Nor A Nor Muhammad, Yu-Yen Chen, Nada Slakeski, Benjamin Peng, Lianyi Zhang, Stuart G Dashper, Keith J Cross, Steven M Cleal, Caroline Moore, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

Spheres of influence: Porphyromonas gingivalis outer membrane vesicles

MJ Gui, SG Dashper, N Slakeski, Y-Y Chen, EC Reynolds

Journal article  |  2016  |  Molecular Oral Microbiology

Bacterial interactions in pathogenic subgingival plaque

Hong Min Ng, Lin Xin Kin, Stuart G Dashper, Nada Slakeski, Catherine A Butler, Eric C Reynolds

Journal article  |  2016  |  Microbial Pathogenesis

Porphyromonas gingivalis and Treponema denticola Exhibit Metabolic Symbioses

Kheng H Tan, Christine A Seers, Stuart G Dashper, Helen L Mitchell, James S Pyke, Vincent Meuric, Nada Slakeski, Steven M Cleal, Jenny L Chambers, Malcolm J McConville, Eric C Reynolds

Journal article  |  2014  |  PLoS Pathogens

Porphyromonas gingivalis and Treponema denticola Synergistic Polymicrobial Biofilm Development

Ying Zhu, Stuart G Dashper, Yu-Yen Chen, Simon Crawford, Nada Slakeski, Eric C Reynolds

Journal article  |  2013  |  PLoS One

Propeptide-Mediated Inhibition of Cognate Gingipain Proteinases

N Laila Huq, Christine A Seers, Elena CY Toh, Stuart G Dashper, Nada Slakeski, Lianyi Zhang, Brent R Ward, Vincent Meuric, Dina Chen, Keith J Cross, Eric C Reynolds

Journal article  |  2013  |  PLoS One

Reversible redox regulation of specificityof Arg-gingipain B in Porphyromonas gingivalis

Yu-Yen Chen, Christine A Seers, Nada Slakeski, Caroline Moore, Lianyi Zhang, Eric C Reynolds

Journal article  |  2013  |  FEBS Letters

PG0026 Is the C-terminal Signal Peptidase of a Novel Secretion System of Porphyromonas gingivalis

Michelle D Glew, Paul D Veith, Benjamin Peng, Yu-Yen Chen, Dhana G Gorasia, Qiaohui Yang, Nada Slakeski, Dina Chen, Caroline Moore, Simon Crawford, Eric C Reynolds

Journal article  |  2012  |  Journal of Biological Chemistry

C-Terminal Domain Residues Important for Secretion and Attachment of RgpB in Porphyromonas gingivalis

Nada Slakeski, Christine A Seers, Kaiting Ng, Caroline Moore, Steven M Cleal, Paul D Veith, Alvin W Lo, Eric C Reynolds

Journal article  |  2011  |  Journal of Bacteriology

Treponema denticola biofilm-induced expression of a bacteriophage, toxin-antitoxin systems and transposases

Helen L Mitchell, Stuart G Dashper, Deanne V Catmull, Rita A Paolini, Steven M Cleal, Nada Slakeski, Kheng H Tan, Eric C Reynolds

Journal article  |  2010  |  Microbiology

Response of Porphyromonas gingivalis to Heme Limitation in Continuous Culture

Stuart G Dashper, Ching-Seng Ang, Paul D Veith, Helen L Mitchell, Alvin WH Lo, Christine A Seers, Katrina A Walsh, Nada Slakeski, Dina Chen, J Patricia Lissel, Catherine A Butler, Neil M O'Brien-Simpson, Ian G Barr, Eric C Reynolds

Journal article  |  2009  |  Journal of Bacteriology

Comparative transcriptomic analysis of Porphyromonas gingivalis biofilm and planktonic cells

Alvin W Lo, Christine A Seers, John D Boyce, Stuart G Dashper, Nada Slakeski, J Patricia Lissel, Eric C Reynolds

Journal article  |  2009  |  BMC Microbiology

P. gingivalis antigenic composition

E REYNOLDS, N SLAKESKI, CG Chen, IG Barr

Patent  |  2008

Kgp and RgpB, but not RgpA, are important for Porphyromonas gingivalis virulence in the murine periodontitis model

Rishi D Pathirana, Neil M O'Brien-Simpson, Gail C Brammar, Nada Slakeski, Eric C Reynolds

Journal article  |  2007  |  Infection and Immunity

Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with Porphyromonas gingivalis

E REYNOLDS, N O'BRIEN-SIMPSON, N SLAKESKI

Patent  |  2007

Vaccination with recombinant adhesins from the RgpA-Kgp proteinase-adhesin complex protects against Porphyromonas gingivalis infection

Leanne T Frazer, Neil M O'Brien-Simpson, Nada Slakeski, Katrina A Walsh, Paul D Veith, Chao Guang Chen, Ian G Barr, Eric C Reynolds

Journal article  |  2006  |  Vaccine

The RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalis

Christine A Seers, Nada Slakeski, Paul D Veith, Todd Nikolof, Yu-Yen Chen, Stuart G Dashper, Eric C Reynolds

Journal article  |  2006  |  Journal of Bacteriology

Role of oxyR in the oral anaerobe Porphyromonas gingivalis

PI Diaz, N Slakeski, EC Reynolds, R Morona, AH Rogers, PE Kolenbrander

Journal article  |  2006  |  Journal of Bacteriology

Hemoglobin hydrolysis and heme acquisition by Porphyromonas gingivalis

SG Dashper, KJ Cross, N Slakeski, P Lissel, P Aulakh, C Moore, EC Reynolds

Journal article  |  2004  |  Oral Microbiology and Immunology

Haemoglobin hydrolysis and haem acquisition by Porphyromonas gingivalis.

SG Dashper, P Aulakh, P Lissel, N Slakeski, K Cross, EC Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

Expression of a recombinant Porphyromonas gingivalis adhesin, Kgp39, and analysis of its immunogenicity using the murine lesion model.

L Taylor, N Slakeski, R Paolini, N O'Brien-Simpson, E Reynolds

Conference Proceedings  |  2003  |  JOURNAL OF DENTAL RESEARCH

Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis

E REYNOLDS, N SLAKESKI, A Hendtlass

Patent  |  2003

Diagnostics and treatments of periodontal disease

E REYNOLDS, P Bhogal, N SLAKESKI

Patent  |  2003

CPG70 is a novel basic metallocarboxypeptidase with C-terminal polycystic kidney disease domains from Porphyromonas gingivalis

YY Chen, KJ Cross, RA Paolini, JE Fielding, N Slakeski, EC Reynolds

Journal article  |  2002  |  Journal of Biological Chemistry

Characterization and expression of a novel Porphyromonas gingivalis outer membrane protein, Omp28

N Slakeski, M Margetts, C Moore, L Czajkowski, IG Barr, EC Reynolds

Journal article  |  2002  |  Oral Microbiology and Immunology

Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model

PS Rajapakse, NM O'Brien-Simpson, N Slakeski, B Hoffmann, EC Reynolds

Journal article  |  2002  |  Infection and Immunity

Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50.

Paul D Veith, Gert H Talbo, Nada Slakeski, Stuart G Dashper, Caroline Moore, Rita A Paolini, Eric C Reynolds

Journal article  |  2002  |  Biochemical Journal

Porphyromonas gingivalis is an anaerobic, asaccharolytic Gram-negative rod associated with chronic periodontitis. We have undertak..

Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50

PD Veith, GH Talbo, N Slakeski, SG Dashper, C Moore, RA Paolini, EC Reynolds

Journal article  |  2002  |  Biochemical Journal

Role of RgpA, RgpB, and Kgp proteinases in virulence of Porphyromonas gingivalis W50 in a murine lesion model

NM O'Brien-Simpson, RA Paolini, B Hoffman, N Slakeski, SG Dashper, EC Reynolds

Journal article  |  2001  |  Infection and Immunity

Identification of a novel heterodimeric outer membrane protein of Porphyromonas gingivalis by two-dimensional gel electrophoresis and peptide mass fingerprinting

PD Veith, GH Talbo, N Slakeski, EC Reynolds

Journal article  |  2001  |  European Journal of Biochemistry

Sodium ion-driven serine/threonine transport in Porphyromonas gingivalis

SG Dashper, L Brownfield, N Slakeski, PS Zilm, AH Rogers, EC Reynolds

Journal article  |  2001  |  Journal of Bacteriology

A Porphyromonas gingivalis genetic locus encoding a heme transport system

N Slakeski, SG Dashper, P Cook, C Poon, C Moore, EC Reynolds

Journal article  |  2000  |  Oral Microbiology and Immunology

Characterization of a novel outer membrane hemin-binding protein of Porphyromonas gingivalis

SG Dashper, A Hendtlass, N Slakeski, C Jackson, KJ Cross, L Brownfield, R Hamilton, I Barr, EC Reynolds

Journal article  |  2000  |  Journal of Bacteriology

A consensus Porphyromonas gingivalis promoter sequence

CA Jackson, B Hoffmann, N Slakeski, S Cleal, AJ Hendtlass, EC Reynolds

Journal article  |  2000  |  FEMS Microbiology Letters

A consensus Porphyromonas gingivalis promoter sequence.

CA Jackson, B Hoffmann, N Slakeski, S Cleal, AJ Hendtlass, EC Reynolds

Journal article  |  2000  |  FEMS Microbiology Letters

We have determined the transcription start points (tsp) for recently identified Porphyromonas gingivalis W50 genes, kgp, rgpA, rgp..

A Porphyromonas gingivalis hemin transport system.

N Slakeski, C Poon, P Cook, EC Reynolds

Conference Proceedings  |  2000  |  JOURNAL OF DENTAL RESEARCH

Serum immunoglobulin G (IgG) and IgG subclass responses to the RgpA-Kgp proteinase-adhesin complex of Porphyromonas gingivalis in adult periodontitis

NM O'Brien-Simpson, CL Black, PS Bhogal, SM Cleal, N Slakeski, TJ Higgins, EC Reynolds

Journal article  |  2000  |  Infection and Immunity

Characterization of a Porphyromonas gingivalis gene prtK that encodes a lysine-specific cysteine proteinase and three sequence-related adhesins

N Slakeski, SM Cleal, PS Bhogal, EC Reynolds

Journal article  |  1999  |  Oral Microbiology and Immunology

Characterization of a second cell-associated Arg-specific cysteine proteinase of Porphyromonas gingivalis and identification of an adhesin-binding motif involved in association of the prtR and prtK proteinases and adhesins into large complexes

N Slakeski, PS Bhogal, NM O'Brien-Simpson, EC Reynolds

Journal article  |  1998  |  Microbiology

Arg- and Lys-specific cysteine proteinases of Porphyromonas gingivalis W50.

EC Reynolds, N Slakeski, PS Bhogal, N O'Brien-Simpson, P Riley, S Cleal

Conference Proceedings  |  1998  |  JOURNAL OF DENTAL RESEARCH

Characterisation of three Porphyromonas gingivalis cysteine proteinase genes.

N Slakeski, EC Reynolds

Conference Proceedings  |  1998  |  JOURNAL OF DENTAL RESEARCH

Identification of a putative adhesin-binding motif in Porphyromonas gingivalis cysteine proteinase genes.

N Slakeski, NM O'Brien-Simpson, EC Reynolds

Conference Proceedings  |  1998  |  JOURNAL OF DENTAL RESEARCH

A cell-associated protein complex of Porphyromonas gingivalis W50 composed of Arg- and Lys-specific cysteine proteinases and adhesins

PS Bhogal, N Slakeski, EC Reynolds

Journal article  |  1997  |  Microbiology

Characterization of a Porphyromonas gingivalis gene prtR that encodes an arginine-specific thiol proteinase and multiple adhesins

N Slakeski, SM Cleal, EC Reynolds

Journal article  |  1996  |  Biochemical and Biophysical Research Communications

NUCLEOTIDE-SEQUENCE OF A GENE (PRTR) ENCODING AN ARGININE-SPECIFIC ENDOPEPTIDASE FROM PORPHYROMONAS-GINGIVALIS

C SOTIROPOULOS, L KIRSZBAUM, N SLAKESKI, C JACKSON, S CLEAL, EC REYNOLDS

Conference Proceedings  |  1995  |  JOURNAL OF DENTAL RESEARCH

COMPLETE NUCLEOTIDE-SEQUENCE OF A GENE PRTR OF PORPHYROMONAS-GINGIVALIS W50 ENCODING A 132KDA PROTEIN THAT CONTAINS AN ARGININE-SPECIFIC THIOL ENDOPEPTIDASE DOMAIN AND A HEMAGGLUTININ DOMAIN

L KIRSZBAUM, C SOTIROPOULOS, C JACKSON, S CLEAL, N SLAKESKI, EC REYNOLDS

Journal article  |  1995  |  Biochemical and Biophysical Research Communications

COMPLETE NUCLEOTIDE-SEQUENCE OF A GENE PRTR OF PORPHYROMONAS-GINGIVALIS W50

L KIRSZBAUM, C SOTIROPOULOS, C JACKSON, S CLEAL, N SLAKESKI, EC REYNOLDS

Conference Proceedings  |  1995  |  JOURNAL OF DENTAL RESEARCH

BARLEY (1-]3,1-]4)-BETA-GLUCANASE ISOENZYME EI-GENE EXPRESSION IS MEDIATED BY AUXIN AND GIBBERELLIC-ACID

N SLAKESKI, GB FINCHER

Journal article  |  1992  |  FEBS Letters

Treatment of young barley leaves with indole acetic acid (IAA) or gibberellic acid (GA3) results in a dramatic increase in levels ..

DEVELOPMENTAL REGULATION OF (1-]3,1-]4)-BETA-GLUCANASE GENE-EXPRESSION IN BARLEY - TISSUE-SPECIFIC EXPRESSION OF INDIVIDUAL ISOENZYMES

N SLAKESKI, GB FINCHER

Journal article  |  1992  |  Plant Physiology

STRUCTURE AND TISSUE-SPECIFIC REGULATION OF GENES ENCODING BARLEY (1-]3, 1-]4)-BETA-GLUCAN ENDOHYDROLASES

N SLAKESKI, DC BAULCOMBE, KM DEVOS, B AHLUWALIA, DNP DOAN, GB FINCHER

Journal article  |  1990  |  MGG Molecular & General Genetics

Two genes encode (1----3, 1----4)-beta-glucan 4-glucanohydrolase (EC 3.2.1.73) isoenzymes in barley. A gene for isoenzyme EI has b..