Nada Slakeski

Metabolic cooperativity betweenPorphyromonas gingivalisandTreponema denticola

Lin Xin Kin, Catherine A Butler, Nada Slakeski, Brigitte Hoffmann, Stuart G Dashper, Eric C Reynolds

Journal article  |  2020  |  JOURNAL OF ORAL MICROBIOLOGY

BACKGROUND:  Porphyromonas gingivalis and Treponema denticola are proteolytic periodontopathogens that co-localize in polymicrobia..

The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis

Hong Min Ng, Nada Slakeski, Catherine A Butler, Paul D Veith, Yu-Yen Chen, Sze Wei Liu, Brigitte Hoffmann, Stuart G Dashper, Eric C Reynolds

Journal article  |  2019  |  FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Chronic periodontitis has a polymicrobial biofilm etiology and interactions between key oral bacterial species, such as Porphyromo..

A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis

Neil M O'Brien-Simpson, James A Holden, Jason C Lenzo, Yan Tan, Gail C Brammar, Katrina A Walsh, William Singleton, Rebecca KH Orth, Nada Slakeski, Keith J Cross, Ivan B Darby, Dorit Becher, Tony Rowe, Adriana Baz Morelli, Andrew Hammet, Andrew Nash, Anna Brown, Bing Ma, Didier Vingadassalom, Jacqueline McCluskey, et al.

Journal article  |  2016  |  NPJ VACCINES

Porphyromonas gingivalis infected mice with an established P. gingivalis-specific inflammatory immune response were protected from..

PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System

Jacqueline E Heath, Christine A Seers, Paul D Veith, Catherine A Butler, Nor A Nor Muhammad, Yu-Yen Chen, Nada Slakeski, Benjamin Peng, Lianyi Zhang, Stuart G Dashper, Keith J Cross, Steven M Cleal, Caroline Moore, Eric C Reynolds

Journal article  |  2016  |  PLOS ONE

Porphyromonas gingivalis utilises the Bacteroidetes-specific type IX secretion system (T9SS) to export proteins across the outer m..

Spheres of influence: Porphyromonas gingivalis outer membrane vesicles

MJ Gui, SG Dashper, N Slakeski, Y-Y Chen, EC Reynolds

Journal article  |  2016  |  MOLECULAR ORAL MICROBIOLOGY

Outer membrane vesicles (OMVs) are asymmetrical single bilayer membranous nanostructures produced by Gram-negative bacteria import..

Bacterial interactions in pathogenic subgingival plaque

Hong Min Ng, Lin Xin Kin, Stuart G Dashper, Nada Slakeski, Catherine A Butler, Eric C Reynolds

Journal article  |  2016  |  MICROBIAL PATHOGENESIS

Chronic periodontitis has a polymicrobial biofilm aetiology. Polymicrobial biofilms are complex, dynamic microbial communities for..

Porphyromonas gingivalis and Treponema denticola Exhibit Metabolic Symbioses

Kheng H Tan, Christine A Seers, Stuart G Dashper, Helen L Mitchell, James S Pyke, Vincent Meuric, Nada Slakeski, Steven M Cleal, Jenny L Chambers, Malcolm J McConville, Eric C Reynolds

Journal article  |  2014  |  PLOS PATHOGENS

Porphyromonas gingivalis and Treponema denticola are strongly associated with chronic periodontitis. These bacteria have been co-l..

Propeptide-Mediated Inhibition of Cognate Gingipain Proteinases

N Laila Huq, Christine A Seers, Elena CY Toh, Stuart G Dashper, Nada Slakeski, Lianyi Zhang, Brent R Ward, Vincent Meuric, Dina Chen, Keith J Cross, Eric C Reynolds

Journal article  |  2013  |  PLOS ONE

Porphyromonas gingivalis is a major pathogen associated with chronic periodontitis. The organism's cell-surface cysteine proteinas..

Reversible redox regulation of specificityof Arg-gingipain B in Porphyromonas gingivalis

Yu-Yen Chen, Christine A Seers, Nada Slakeski, Caroline Moore, Lianyi Zhang, Eric C Reynolds

Journal article  |  2013  |  FEBS LETTERS

Arg-gingipain B (RgpB), a major virulence factor secreted by the periodontal pathogen Porphyromonas gingivalis is an Arg-specific ..

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth

Yi Zhu, Karla MP Pires, Kevin J Whitehead, Curtis D Olsen, Benjamin Wayment, Yi Cheng Zhang, Heiko Bugger, Olesya Ilkun, Sheldon E Litwin, George Thomas, Sara C Kozma, E Dale Abel

Journal article  |  2013  |  PLOS ONE

Chronic periodontitis has a polymicrobial biofilm aetiology and interactions between key bacterial species are strongly implicated..