Laura Vella

Non-invasive screening of a microRNA-based dysregulation signature in oral cancer and oral potentially malignant disorders

T Yap, C Seers, K Koo, L Cheng, LJ Vella, AF Hill, E Reynolds, A Nastri, N Cirillo, M McCullough

Journal article  |  2019  |  Oral Oncology

Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth

Luan Luu, Giuseppe D Ciccotosto, Laura J Vella, Lesley Cheng, Laila C Roisman, Gerhard Multhaup, Andrew F Hill, Lisa-Marie Munter, Roberto Cappai

Journal article  |  2019  |  Molecular Neurobiology

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Thery, Kenneth W Witwer, Elena Aikawa, Maria Jose Alcaraz, Johnathon D Anderson, Ramaroson Andriantsitohaina, Anna Antoniou, Tanina Arab, Fabienne Archer, Georgia K Atkin-Smith, D Craig Ayre, Jean-Marie Bach, Daniel Bachurski, Hossein Baharvand, Leonora Balaj, Shawn Baldacchino, Natalie N Bauer, Amy A Baxter, Mary Bebawy, Carla Beckham, et al.

Journal article  |  2019  |  Journal of Extracellular Vesicles

Predicting the Presence of Oral Squamous Cell Carcinoma Using Commonly Dysregulated MicroRNA in Oral Swirls

Tami Yap, Kendrick Koo, Lesley Cheng, Laura J Vella, Andrew F Hill, Eric Reynolds, Alf Nastri, Nicola Cirillo, Christine Seers, Michael McCullough

Journal article  |  2018  |  Cancer Prevention Research

Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease

Leah C Beauchamp, Jacky Chan, Lin W Hung, Benjamin S Padman, Laura J Vella, Xiang M Liu, Bradley Coleman, Ashley I Bush, Michael Lazarou, Andrew F Hill, Laura Jacobson, Kevin J Barnham

Journal article  |  2018  |  Acta Neuropathologica Communications

Intercellular Resistance to BRAF Inhibition Can Be Mediated by Extracellular Vesicle-Associated PDGFR beta

Laura J Vella, Andreas Behren, Bradley Coleman, David W Greening, Andrew F Hill, Jonathan Cebon

Journal article  |  2017  |  Neoplasia

A rigorous method to enrich for exosomes from brain tissue

Laura J Vella, Benjamin J Scicluna, Lesley Cheng, Emma G Bawden, Colin L Masters, Ching-Seng Ang, Nicholas Willamson, Catriona McLean, Kevin J Barnham, Andrew F Hill

Journal article  |  2017  |  Journal of Extracellular Vesicles

Generation of Infectious Prions and Detection with the Prion-Infected Cell Assay

Laura J Vella, Bradley Coleman, Andrew F Hill

Journal article  |  2017  |  Methods in molecular biology (Clifton, N.J.)

The contribution of tumour-derived exosomes to the hallmarks of cancer

Katie Meehan, Laura J Vella

Journal article  |  2016  |  Critical Reviews in Clinical Laboratory Sciences

Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease

Laura J Vella, Andrew F Hill, Lesley Cheng

Journal article  |  2016  |  International Journal of Molecular Sciences

EVpedia: a community web portal for extracellular vesicles research

Dae-Kyum Kim, Jaewook Lee, Sae Rom Kim, Dong-Sic Choi, Yae Jin Yoon, Ji Hyun Kim, Gyeongyun Go, Dinh Nhung, Kahye Hong, Su Chul Jang, Si-Hyun Kim, Kyong-Su Park, Oh Youn Kim, Hyun Taek Park, Ji Hye Seo, Elena Aikawa, Monika Baj-Krzyworzeka, Bas WM van Balkom, Mattias Belting, Lionel Blanc, et al.

Journal article  |  2015  |  Bioinformatics

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma

Aparna Jayachandran, Matthew Anaka, Prashanth Prithviraj, Christopher Hudson, Sonja J McKeown, Pu-Han Lo, Laura J Vella, Colin R Goding, Jonathan Cebon, Andreas Behren

Journal article  |  2014  |  Oncotarget

The kinase inhibitors dabrafenib and trametinib affect isolated immune cell populations

Laura J Vella, Miles C Andrews, Anupama Pasam, Katherine Woods, Andreas Behren, Jonathan S Cebon

Journal article  |  2014  |  OncoImmunology

MEK Inhibition, Alone or in Combination with BRAF Inhibition, Affects Multiple Functions of Isolated Normal Human Lymphocytes and Dendritic Cells

Laura J Vella, Anupama Pasam, Nektaria Dimopoulos, Miles Andrews, Ashley Knights, Anne-Laure Puaux, Jamila Louahed, Weisan Chen, Katherine Woods, Jonathan S Cebon

Journal article  |  2014  |  Cancer Immunology Research

The emerging role of exosomes in epithelial-mesenchymal-transition in cancer.

Laura Jayne Vella

Journal article  |  2014  |  Frontiers in Oncology

Metastasis in cancer consists of multiple steps, including epithelial-mesenchymal-transition (EMT), which is characterized by the ..

BRAF Inhibitor-Driven Tumor Proliferation in a KRAS-Mutated Colon Carcinoma Is Not Overcome by MEK1/2 Inhibition

Miles C Andrews, Andreas Behren, Fiona Chionh, John Mariadason, Laura J Vella, Hongdo Do, Alexander Dobrovic, Niall Tebbutt, Jonathan Cebon

Journal article  |  2013  |  Journal of Clinical Oncology

The Ludwig Institute for Cancer Research Melbourne Melanoma Cell Line Panel

Andreas Behren, Matthew Anaka, Pu-Han Lo, Laura J Vella, Ian D Davis, Jenny Catimel, Tracy Cardwell, Craig Gedye, Christopher Hudson, Rodica Stan, Jonathan Cebon

Journal article  |  2013  |  Pigment Cell & Melanoma Research

The Amyloid Precursor Protein Copper Binding Domain Histidine Residues 149 and 151 Mediate APP Stability and Metabolism

Loredana Spoerri, Laura J Vella, Chi LL Pham, Kevin J Barnham, Roberto Cappai

Journal article  |  2012  |  Journal of Biological Chemistry

Identification of a novel amyloid precursor protein processing pathway that generates secreted N-terminal fragments

Laura J Vella, Roberto Cappai

Journal article  |  2012  |  FASEB Journal

FOXP3 is not mutated in human melanoma

BeeShin Tan, Andreas Behren, Matthew Anaka, Laura Vella, Jonathan Cebon, John M Mariadason, Weisan Chen

Journal article  |  2012  |  Pigment Cell & Melanoma Research

C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

Jodi Meyerowitz, Sarah J Parker, Laura J Vella, Dominic CH Ng, Katherine A Price, Jeffrey R Liddell, Aphrodite Caragounis, Qiao-Xin Li, Colin L Masters, Takashi Nonaka, Masato Hasegawa, Marie A Bogoyevitch, Katja M Kanninen, Peter J Crouch, Anthony R White

Journal article  |  2011  |  Molecular Neurodegeneration

PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site

Cathryn L Haigh, Victoria A Lewis, Laura J Vella, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins

Journal article  |  2009  |  Cell Research

Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid

Laura J Vella, Deanne LV Greenwood, Roberto Cappai, Jean-Pierre Y Scheerlinck, Andrew F Hill

Journal article  |  2008  |  Veterinary Immunology and Immunopathology

Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

Robyn A Sharples, Laura J Vella, Rebecca M Nisbet, Ryan Naylor, Keyla Perez, Kevin J Barnham, Colin L Masters, Andrew F Hill

Journal article  |  2008  |  FASEB Journal

The role of exosomes in the processing of proteins associated with neurodegenerative diseases

Laura J Vella, Robyn A Sharples, Rebecca M Nisbet, Roberto Cappai, Andrew F Hill

Journal article  |  2008  |  European Biophysics Journal

Generation of cell lines propagating infectious prions and the isolation and characterization of cell-derived exosomes.

Laura J Vella, Andrew F Hill

Book Chapter  |  2008  |  Methods in Molecular Biology

Prion-propagating cell lines are an efficient and useful means for studying the cellular and molecular mechanisms implicated in pr..

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture

Victoria A Lawson, Laura J Velia, James D Stewart, Robyn A Sharples, Helen Klemm, Dorothy M Machalek, Colin L Masters, Roberto Cappai, Steven J Collins, Andrew F Hill

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.

V LAWSON, L VELLA, J STEWART, R SHARPLES, H KLEMM, D MACHALEK, C MASTERS, R Cappai, SJ Collins, A HILL

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

Generation of cell lines propagating infectious prions and the isolation and characterization of cell-derived exosomes

LJ Vella, AF Hill

Journal article  |  2008  |  Methods in Molecular Biology

Packaging of prions into exosomes is associated with a novel pathway of PrP processing

LJ Vella, RA Sharples, VA Lawson, CL Masters, R Cappai, AF Hill

Journal article  |  2007  |  Journal of Pathology

Alteration of the proline at position 7 of the HIV-1 spacer peptide p1 suppresses viral infectivity in a strain dependent manner.

Melissa K Hill, Anna Bellamy-McIntyre, Laura J Vella, Shahan M Campbell, John A Marshall, Gilda Tachedjian, Johnson Mak

Journal article  |  2007  |  Current HIV Research

The HIV-1 spacer peptide p1 is located in the C-terminus of the Gag polyprotein and separates the nucleocapsid (NC) and p6(Gag). R..

Investigating the propagation and spread of infectious prions in neuronal cells

LJ Vella, RA Sharples, CL Masters, R Cappai, AF Hill

Conference Proceedings  |  2006  |  JOURNAL OF NEUROCHEMISTRY

Mechanisms of prion toxicity and their relationship to prion infectivity

L Vella, AF Hill, R Cappai

Book Chapter  |  2005

Investigations into the propagation and spread of infectious prions in cultured cells

AF Hill, LJ Vella, RA Sharples, VA Lawson, SJ Collins, R Cappai, CL Masters

Conference Proceedings  |  2005  |  JOURNAL OF NEUROCHEMISTRY

Proteomic investigation into the propagation and spread of infectious prions in non-neuronal cells.

LJ Vella, RA Sharples, VA Lawson, SJ Collins, CL Masters, R Cappai, AF Hill

Conference Proceedings  |  2005  |  FEBS JOURNAL