James Hurley

Asymmetric Effects of Decontamination Using Topical Antibiotics for the ICU Patient

James C Hurley

Journal article  |  2021  |  SYMMETRY-BASEL

There are several antiseptic, antibiotic and non-decontamination-based interventions for preventing intensive care unit (ICU) acqu..

Could simulation methods solve the curse of sparse data within clinical studies of antibiotic resistance?

James C Hurley, David Brownridge

Journal article  |  2021  |  JAC Antimicrob Resist

Infectious disease (ID) physicians and ID pharmacists commonly confront therapeutic questions relating to antibiotic resistance. R..

Candida-Acinetobacter-Pseudomonas Interaction Modelled within 286 ICU Infection Prevention Studies

James C Hurley

Journal article  |  2020  |  JOURNAL OF FUNGI

BACKGROUND: Whether Candida interacts to enhance the invasive potential of Acinetobacter and Pseudomonas bacteria cannot be resolv..

Estimated Treatment Effects of Tight Glycaemic Targets in Mild Gestational Diabetes Mellitus: A Multiple Cut-Off Regression Discontinuity Study Design

David Song, James C Hurley, Maryanne Lia

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

Background: We investigated the treatment effects of tight glycaemic targets in a population universally screened according to the..

Oral Vancomycin Prophylaxis for Clostridioides difficile infection; cause or effect?

James C Hurley

Journal article  |  2020  |  Clin Infect Dis

Structural equation modeling the "control of gut overgrowth" in the prevention of ICU-acquired Gram-negative infection

James C Hurley

Journal article  |  2020  |  CRITICAL CARE

BACKGROUND: Conceptually, the "control of gut overgrowth" (COGO) is key in mediating prevention against infection with Gram-negati..

Selective Digestive Decontamination Is Neither Safe Nor Efficacious for Critically Ill Patients

James C Hurley

Journal article  |  2020  |  CRITICAL CARE MEDICINE

Forrest plots or caterpillar plots?

James C Hurley

Journal article  |  2020  |  JOURNAL OF CLINICAL EPIDEMIOLOGY

Antibiotics in the ICU; benefit or harm?

James C Hurley

Journal article  |  2020  |  INTENSIVE CARE MEDICINE

How the Cluster-randomized Trial "Works"

James C Hurley

Journal article  |  2020  |  CLINICAL INFECTIOUS DISEASES

Cluster-randomized trials (CRTs) are able to address research questions that randomized controlled trials (RCTs) of individual pat..