Antony Burgess

Regulation of Signaling from the Epidermal Growth Factor Family.

Antony W Burgess

Journal article  |  2022  |  J Phys Chem B

The epidermal growth factor (EGF) system has allowed chemists, biologists, and clinicians to improve our understanding of cell pro..

Dual drug targeting to kill colon cancers.

Silvia Paola Corona, Francesca Walker, Janet Weinstock, Guillaume Lessene, Maree Faux, Antony W Burgess

Journal article  |  2022  |  Cancer Med

INTRODUCTION: Colorectal cancer (CRC) is driven by a small set of oncogenic and tumour suppressor mutations. However, different co..

Combined Treatment with a WNT Inhibitor and the NSAID Sulindac Reduces Colon Adenoma Burden in Mice with Truncated APC.

Maree C Faux, Janet Weinstock, Sophia Gogos, Emma Prato, Alexander I Azimpour, Ryan O'Keefe, Yasmin Cathcart-King, Alexandra L Garnham, Matthias Ernst, Adele Preaudet, Michael Christie, Tracy L Putoczki, Michael Buchert, Antony W Burgess

Journal article  |  2022  |  Cancer Res Commun

UNLABELLED: Adenomatous polyposis coli (APC) truncations occur in many colorectal cancers and are often associated with immune inf..

Regulation of Signaling from the Epidermal Growth Factor Family

AW Burgess

Journal article  |  2022  |  Journal of Physical Chemistry C

The epidermal growth factor (EGF) system has allowed chemists, biologists, and clinicians to improve our understanding of cell pro..

Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1(-/-) mice

Jun T Low, Gwo-Yaw Ho, Mark Scott, Chin Wee Tan, Lachlan Whitehead, Kathy Barber, Hon YK Yip, Johanna F Dekkers, Yumiko Hirokawa, John Silke, Antony W Burgess, Andreas Strasser, Tracy L Putoczki, Lorraine A O'Reilly

Journal article  |  2021  |  CELL DEATH & DISEASE

The Diverse Applications of Pancreatic Ductal Adenocarcinoma Organoids

Ronnie Ren Jie Low, Wei Wen Lim, Paul M Nguyen, Belinda Lee, Michael Christie, Antony W Burgess, Peter Gibbs, Sean M Grimmond, Frederic Hollande, Tracy L Putoczki

Journal article  |  2021  |  CANCERS

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies. While immortalized cancer cell lines and gen..

Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Yumiko Hirokawa, Jordan Clarke, Michelle Palmieri, Tao Tan, Dmitri Mouradov, Shan Li, Cong Lin, Fuqiang Li, Huijuan Luo, Kui Wu, Maree Faux, Chin Wee Tan, Margaret Lee, Grace Gard, Peter Gibbs, Antony W Burgess, Oliver M Sieber

Journal article  |  2021  |  COMMUNICATIONS BIOLOGY

Cell embedment into a solid support matrix is considered essential for the culture of intestinal epithelial organoids and tumoroid..

Immunohistochemical evaluation of the prognostic and predictive power of epidermal growth factor receptor ligand levels in patients with metastatic colorectal cancer

Siavash Foroughi, Ryan A Hutchinson, Hui-li Wong, Michael Christie, Ahida Batrouney, Rachel Wong, Margaret Lee, Jeanne Tie, Antony Wilks Burgess, Peter Gibbs

Journal article  |  2021  |  GROWTH FACTORS

For patients with metastatic colorectal cancer (mCRC), epidermal growth factor receptor (EGFR) inhibitors are limited to patients ..

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

Christoph Grohmann, Francesca Walker, Mark Devlin, Meng-Xiao Luo, Anderly C Chueh, Judy Doherty, Francois Vaillant, Gwo-Yaw Ho, Matthew J Wakefield, Clare E Weeden, Alvin Kamili, Jayne Murray, Sela T Po'uha, Janet Weinstock, Serena R Kane, Maree C Faux, Esmee Broekhuizen, Ye Zheng, Kristy Shield-Artin, Nadia J Kershaw, et al.

Journal article  |  2021  |  CELL DEATH & DISEASE

Targeting cell division by chemotherapy is a highly effective strategy to treat a wide range of cancers. However, there are limita..

Genomic Signature of Oral Squamous Cell Carcinomas from Non-Smoking Non-Drinking Patients

Kendrick Koo, Dmitri Mouradov, Christopher M Angel, Tim A Iseli, David Wiesenfeld, Michael J McCullough, Antony W Burgess, Oliver M Sieber

Journal article  |  2021  |  CANCERS

Molecular alterations in 176 patients with oral squamous cell carcinomas (OSCC) were evaluated to delineate differences in non-smo..