Aimee Tan

A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA.

Zhenyao Luo, Jacqueline R Morey, Evelyne Deplazes, Alina Motygullina, Aimee Tan, Katherine Ganio, Stephanie L Neville, Nikolaos Eleftheriadis, Michael Isselstein, Victoria G Pederick, James C Paton, Thorben Cordes, Jeffrey R Harmer, Bostjan Kobe, Christopher A McDevitt

Journal article  |  2021  |  mBio

Zinc is an essential element in all domains of life. Nonetheless, how prokaryotes achieve selective acquisition of zinc from the e..

Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis

David MP De Oliveira, Lisa Bohlmann, Trent Conroy, Freda E-C Jen, Arun Everest-Dass, Karl A Hansford, Raghu Bolisetti, Ibrahim M El-Deeb, Brian M Forde, Phan Minh-Duy, Jake A Lacey, Aimee Tan, Tania Rivera-Hernandez, Stephan Brouwer, Nadia Keller, Timothy J Kidd, Amanda J Cork, Michelle J Bauer, Gregory M Cook, Mark R Davies, et al.

Journal article  |  2020  |  Science Translational Medicine

The emergence of polymyxin resistance in carbapenem-resistant and extended-spectrum β-lactamase (ESBL)-producing bacteria is a cri..

Moraxella catarrhalisphase-variable loci show differences in expression during conditions relevant to disease

Aimee Tan, Luke V Blakeway, undefined Taha, Yuedong Yang, Yaoqi Zhou, John M Atack, Ian R Peak, Kate L Seib

Journal article  |  2020  |  PLoS One

Moraxella catarrhalis is a human-adapted, opportunistic bacterial pathogen of the respiratory mucosa. Although asymptomatic coloni..

Transcriptome RNA Sequencing Data Set of Gene Expression in Moraxella catarrhalis On- and Off-Phase Variants of the Type III DNA Methyltransferase ModM3

Luke V Blakeway, Aimee Tan, Ian R Peak, John M Atack, Kate L Seib

Journal article  |  2020  |  Microbiology Resource Announcements

Proteome of a Moraxella catarrhalis Strain under Iron-Restricted Conditions

Luke Blakeway, Aimee Tan, Ian R Peak, John M Atack, Kate L Seib

Journal article  |  2020  |  Microbiology Resource Announcements

Moraxella catarrhalis is a leading cause of otitis media and exacerbations of chronic obstructive pulmonary disease; however, its ..

The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media.

Luke V Blakeway, Aimee Tan, Joseph A Jurcisek, Lauren O Bakaletz, John M Atack, Ian R Peak, Kate L Seib

Journal article  |  2019  |  BMC Microbiology

BACKGROUND: Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic obstructive pulmonary disease (COPD). M. cat..

The Serogroup B Meningococcal Vaccine Bexsero Elicits Antibodies to Neisseria gonorrhoeae

Evgeny A Semchenko, Aimee Tan, Ray Borrow, Kate L Seib

Journal article  |  2019  |  Clinical Infectious Diseases

Background: Neisseria gonorrhoeae and Neisseria meningitidis are closely related bacteria that cause a significant global burden o..

Dietary zinc and the control of Streptococcus pneumoniae infection

Bart A Eijkelkamp, Jacqueline R Morey, Stephanie L Neville, Aimee Tan, Victoria G Pederick, Nerida Cole, Prashina P Singh, Cheryl-Lynn Y Ong, Raquel Gonzalez de Vega, David Clases, Bliss A Cunningham, Catherine E Hughes, Iain Comerford, Erin B Brazel, Jonathan J Whittall, Charles D Plumptre, Shaun R McColl, James C Paton, Alastair G McEwan, Philip A Doble, et al.

Journal article  |  2019  |  PLoS Pathogens

Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding

Aimee Tan, Wing-Sze Li, Anthony D Verderosa, Luke Blakeway, Tsitsi D Mubaiwa, Makrina Totsika, Kate L Seib

Journal article  |  2019  |  Scientific Reports

Screening DNA Repeat Tracts of Phase Variable Genes by Fragment Analysis.

Freda E-C Jen, Kate L Seib, Aimee Tan

Book Chapter  |  2019  |  Methods in Molecular Biology

Fragment analysis (or fragment length analysis) is a PCR-based method which allows quantification of the size and proportion of a ..