Aimee Tan

The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media.

Luke V Blakeway, Aimee Tan, Joseph A Jurcisek, Lauren O Bakaletz, John M Atack, Ian R Peak, Kate L Seib

Journal article  |  2019  |  BMC Microbiology

BACKGROUND: Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic obstructive pulmonary disease (COPD). M. cat..

The Serogroup B Meningococcal Vaccine Bexsero Elicits Antibodies to Neisseria gonorrhoeae

Evgeny A Semchenko, Aimee Tan, Ray Borrow, Kate L Seib

Journal article  |  2019  |  Clinical Infectious Diseases

Background: Neisseria gonorrhoeae and Neisseria meningitidis are closely related bacteria that cause a significant global burden o..

Dietary zinc and the control of Streptococcus pneumoniae infection

Bart A Eijkelkamp, Jacqueline R Morey, Stephanie L Neville, Aimee Tan, Victoria G Pederick, Nerida Cole, Prashina P Singh, Cheryl-Lynn Y Ong, Raquel Gonzalez de Vega, David Clases, Bliss A Cunningham, Catherine E Hughes, Iain Comerford, Erin B Brazel, Jonathan J Whittall, Charles D Plumptre, Shaun R McColl, James C Paton, Alastair G McEwan, Philip A Doble, et al.

Journal article  |  2019  |  PLOS Pathogens

Moraxella catarrhalis NucM is an entry nuclease involved in extracellular DNA and RNA degradation, cell competence and biofilm scaffolding

Aimee Tan, Wing-Sze Li, Anthony D Verderosa, Luke Blakeway, Tsitsi D Mubaiwa, Makrina Totsika, Kate L Seib

Journal article  |  2019  |  Scientific Reports

Screening DNA Repeat Tracts of Phase Variable Genes by Fragment Analysis.

Freda E-C Jen, Kate L Seib, Aimee Tan

Book Chapter  |  2019  |  Methods in Molecular Biology

Fragment analysis (or fragment length analysis) is a PCR-based method which allows quantification of the size and proportion of a ..

Moraxella catarrhalis Restriction-Modification Systems Are Associated with Phylogenetic Lineage and Disease

Luke V Blakeway, Aimee Tan, Rachael Lappan, Amir Ariff, Janessa L Pickering, Christopher S Peacock, Christopher C Blyth, Charlene M Kahler, Barbara J Chang, Deborah Lehmann, Lea-Ann S Kirkham, Timothy F Murphy, Michael P Jennings, Lauren O Bakaletz, John M Atack, Ian R Peak, Kate L Seib

Journal article  |  2018  |  Genome Biology and Evolution

Phasevarions of Bacterial Pathogens: Methylomics Sheds New Light on Old Enemies

John M Atack, Aimee Tan, Lauren O Bakaletz, Michael P Jennings, Kate L Seib

Journal article  |  2018  |  Trends in Microbiology

Virulence determinants of Moraxella catarrhalis: distribution and considerations for vaccine development

Luke V Blakeway, Aimee Tan, Ian RA Peak, Kate L Seib

Journal article  |  2017  |  Microbiology

Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic Neisseria

Kate L Seib, Freda E-C Jen, Adeana L Scott, Aimee Tan, Michael P Jennings

Journal article  |  2017  |  Pathogens and Disease

Complete Genome Sequence of Moraxella catarrhalis Strain CCRI-195ME, Isolated from the Middle Ear

Aimee Tan, Luke V Blakeway, Lauren O Bakaletz, Matthew Boitano, Tyson A Clark, Jonas Korlach, Michael P Jennings, Ian R Peak, Kate L Seib

Journal article  |  2017  |  Genome Announcements

The Capricious Nature of Bacterial Pathogens: Phasevarions and vaccine Development

Aimee Tan, John M Atack, Michael P Jennings, Kate L Seib

Journal article  |  2016  |  Frontiers in Immunology

Distribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: implications for gene regulation and virulence

Aimee Tan, Dorothea MC Hill, Odile B Harrison, Yogitha N Srikhanta, Michael P Jennings, Martin CJ Maiden, Kate L Seib

Journal article  |  2016  |  Scientific Reports

Specificity of the ModA11, ModA12 and ModD1 epigenetic regulator N-6-adenine DNA methyltransferases of Neisseria meningitidis

Kate L Seib, Freda E-C Jen, Aimee Tan, Adeana L Scott, Ritesh Kumar, Peter M Power, Li-Tzu Chen, Hsing-Ju Wu, Andrew H-J Wang, Dorothea MC Hill, Yvette A Luyten, Richard D Morgan, Richard J Roberts, Martin CJ Maiden, Matthew Boitano, Tyson A Clark, Jonas Korlach, Desirazu N Rao, Michael P Jennings

Journal article  |  2015  |  Nucleic Acids Research

Evolutionary Adaptation of an AraC-Like Regulatory Protein in Citrobacter rodentium and Escherichia Species

Aimee Tan, Nicola K Petty, Dianna Hocking, Vicki Bennett-Wood, Matthew Wakefield, Judyta Praszkier, Marija Tauschek, Ji Yang, Roy Robins-Browne

Journal article  |  2015  |  Infection and Immunity

Autogenous Transcriptional Regulation of the regA Gene, Encoding an AraC-Like, Essential Virulence Regulator in Citrobacter rodentium

Aimee Tan, Ji Yang, Marija Tauschek, Judyta Praszkier, Roy M Robins-Browne

Journal article  |  2011  |  Journal of Bacteriology

Transcriptional Analysis of the grlRA Virulence Operon from Citrobacter rodentium

Marija Tauschek, Ji Yang, Dianna Hocking, Kristy Azzopardi, Aimee Tan, Emily Hart, Judyta Praszkier, Roy M Robins-Browne

Journal article  |  2010  |  Journal of Bacteriology

Placental hypoxia during placental malaria

Philippe Boeuf, Aimee Tan, Cleofe Romagosa, Jane Radford, Victor Mwapasa, Malcolm E Molyneux, Steven R Meshnick, Nicholas H Hunt, Stephen J Rogerson

Journal article  |  2008  |  Journal of Infectious Diseases