Prof Ian Wicks

Find out more about Ian Wicks' experience

Ian Wicks' highlights

FEATURED Journal article

The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

Ian Wicks' selected work

The Consequences Of Osteoarthritis In Australia: Work Productivity Loss And Health Service..

Research Grant

Leukocyte Tetraspanin CD53 Restrains alpha(3) Integrin Mobilization and Facilitates Cytosk..

Journal article

The Consequences Of Osteoarthritis In Australia: Work Productivity Loss And Health Service..

Research Grant

Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

Journal article

Inflammasomes and Cell Death: Common Pathways in Microparticle Diseases.

Journal article

Circulating small non-coding RNA biomarkers of response to triple DMARD therapy in Caucasi..

Projects

Displaying the 2 most recent projects by Ian Wicks.

The Consequences Of Osteoarthritis In Australia: Work Productivity Loss And Health Service Utilisation

This project will determine the burden of osteoarthritis in Australia. Although osteoarthritis is one of the most common and costly conditio..

2008 - 2010

Completed

The Consequences Of Osteoarthritis In Australia: Work Productivity Loss And Health Service Utilisation

This project will determine the burden of osteoarthritis in Australia. Although osteoarthritis is one of the most common and costly conditio..

2008 - 2010

Completed

2

Projects

Project Types

Research Grant

Scholarly Works

Displaying the 186 most recent scholarly works by Ian Wicks.

Leukocyte Tetraspanin CD53 Restrains alpha(3) Integrin Mobilization and Facilitates Cytoskeletal Remodeling and Transmigration in Mice

Louisa Yeung, Jeremy ML Anderson, Janet L Wee, Maria C Demaria, Michaela Finsterbusch, Yuxin S Liu, Pam Hall, Brodie C Smith, Wendy Dankers, Kirstin D Elgass, Ian P Wicks, Hang Fai Kwok, Mark D Wright, Michael J Hickey

Journal article | 2020 | The Journal of Immunology

The importance of tetraspanin proteins in regulating migration has been demonstrated in many diverse cellular systems. However, th..

Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease

Holly Anderton, Ian P Wicks, John Silke

Journal article | 2020 | Nature Reviews Rheumatology

Inflammasomes and Cell Death: Common Pathways in Microparticle Diseases.

Maryam Rashidi, Ian P Wicks, James E Vince

Journal article | 2020 | Trends in Molecular Medicine

The accumulation of cellular and environmental microparticles has been linked to many diseases associated with tissue inflammation..

Circulating small non-coding RNA biomarkers of response to triple DMARD therapy in Caucasian women with early rheumatoid arthritis.

Andrew D Foers, Alexandra L Garnham, Gordon K Smyth, Susanna M Proudman, Lesley Cheng, Andrew F Hill, Ken C Pang, Ian P Wicks

Journal article | 2020 | The Journal of Rheumatology

OBJECTIVE: To identify small non-coding RNA (sncRNA) serum biomarkers that predict response to triple disease-modifying antirheuma..

Correspondence regarding research letter to the editor by Mathian et al, 'Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus under long-term treatment with hydroxychloroquine'.

Mandana Nikpour, Benjamin Teh, Ian P Wicks, Marc Pellegrini

Journal article | 2020 | Annals of the Rheumatic Diseases

NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

Cynthia Louis, Fernando Souza-Fonseca-Guimaraes, Yuyan Yang, Damian D'Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J Davis, Jeffrey J Babon, Bogoljub Ciric, Eric Vivier, Warren S Alexander, Nicholas D Huntington, Ian P Wicks

Journal article | 2020 | Journal of Experimental Medicine

Despite increasing recognition of the importance of GM-CSF in autoimmune disease, it remains unclear how GM-CSF is regulated at si..

NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS (vol 217, e20191421, 2020)

Cynthia Louis, Fernando Guimaraes, Yuyan Yang, Damian D'Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J Davis, Jeffrey J Babon, Bogoljub Ciric, Eric Vivier, Warren S Alexander, Nicholas D Huntington, Ian P Wicks

Journal article | 2020 | Journal of Experimental Medicine

TBK1 and IKK epsilon Act Redundantly to Mediate STING-Induced NF-kappa B Responses in Myeloid Cells

Katherine R Balka, Cynthia Louis, Tahnee L Saunders, Amber M Smith, Dale J Calleja, Damian B D'Silva, Fiona Moghaddas, Maximilien Tailler, Kate E Lawlor, Yifan Zhan, Christopher J Burns, Ian P Wicks, Jonathan J Miner, Benjamin T Kile, Seth L Masters, Dominic De Nardo

Journal article | 2020 | Cell Reports

Stimulator of Interferon Genes (STING) is a critical component of host innate immune defense but can contribute to chronic autoimm..

Genetic susceptibility to hydroxychloroquine retinal toxicity

Heather G Mack, Tanya Kowalski, Alexis Lucattini, Rc Andrew Symons, Ian Wicks, Anthony Jh Hall

Journal article | 2020 | Ophthalmic Genetics

Background: Hydroxychloroquine retinal toxicity can occur in up to 7.5% of patients receiving treatment; however, possible genetic..

The neutrophil-lymphocyte ratio in early rheumatoid arthritis and its ability to predict subsequent failure of triple therapy

Daniel Boulos, Susanna M Proudman, Robert G Metcalf, Leah McWilliams, Cindy Hall, Ian P Wicks

Journal article | 2019 | Seminars in Arthritis and Rheumatism

SIDT2 RNA Transporter Promotes Lung and Gastrointestinal Tumor Development

Tan A Nguyen, Kathryn T Bieging-Rolett, Tracy L Putoczki, Ian P Wicks, Laura D Attardi, Ken C Pang

Journal article | 2019 | iScience

RNautophagy is a newly described type of selective autophagy whereby cellular RNAs are transported into lysosomes for degradation...

Factors Contributing to Capturing Positive Findings on Temporal Artery Biopsy: An Australian Experience from Two Rheumatology Referral Centers

Victor Yang, Benjamin Sutu, Christopher McMaster, Claire Owen, Alexander Strathmore, Gene-Siew Ngian, Shereen Oon, Jessica Leung, Ian Wicks, Russell Buchanan, David Liew

Conference Proceedings | 2019 | ARTHRITIS & RHEUMATOLOGY

Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling

X Liu, AA D'Cruz, J Hansen, BA Croker, KE Lawlor, NA Sims, IP Wicks

Journal article | 2019 | Osteoarthritis and Cartilage

OBJECTIVE: To investigate the impact of deleting Suppressor of Cytokine Signaling (SOCS)-3 (SOCS3) in chondrocytes during murine s..

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1 beta Release

Maryam Rashidi, Daniel S Simpson, Anne Hempel, Daniel Frank, Emma Petrie, Angelina Vince, Rebecca Feltham, Jane Murphy, Simon M Chatfield, Guy S Salvesen, James M Murphy, Ian P Wicks, James E Vince

Journal article | 2019 | The Journal of Immunology

The pyroptotic cell death effector gasdermin D (GSDMD) is required for murine models of hereditary inflammasome-driven, IL-1β-depe..

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm

Tan A Nguyen, Blake RC Smith, Kirstin D Elgass, Sarah J Creed, Shane Cheung, Michelle D Tate, Gabrielle T Belz, Ian P Wicks, Seth L Masters, Ken C Pang

Journal article | 2019 | The Journal of Immunology

The Selective Expansion and Targeted Accumulation of Bone Marrow-Derived Macrophages Drive Cardiac Vasculitis

Angus T Stock, Nicholas Collins, Gordon K Smyth, Yifang Hu, Jacinta A Hansen, Damian B D'Silva, Hamdi A Jama, Andrew M Lew, Thomas Gebhardt, Catriona A McLean, Ian P Wicks

Journal article | 2019 | The Journal of Immunology

TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease

Angus T Stock, Hamdi A Jama, Jacinta A Hansen, Ian P Wicks

Journal article | 2019 | The Journal of Immunology

All Hands

I Wicks

Journal article | 2019 | JAMA

NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology

Susan Schlenner, Emanuela Pasciuto, Vasiliki Lagou, Oliver Burton, Teresa Prezzemolo, Steffie Junius, Carlos P Roca, Cyril Seillet, Cynthia Louis, James Dooley, Kylie Luong, Erika Van Nieuwenhove, Ian P Wicks, Gabrielle Belz, Stephanie Humblet-Baron, Carine Wouters, Adrian Liston

Journal article | 2019 | Annals of the Rheumatic Diseases

A potential association between IL-3 and type I and III interferons in systemic lupus erythematosus

Shereen Oon, Katherine Monaghan, Milica Ng, Alberta Hoi, Eric Morand, Gino Vairo, Eugene Maraskovsky, Andrew D Nash, Ian P Wicks, Nicholas J Wilson

Journal article | 2019 | Clinical & Translational Immunology

Objectives: Plasmacytoid dendritic cells (pDCs), through the production of type 1 interferons (IFNs) and other cytokines, are majo..

Therapeutic Effects of a TANK-Binding Kinase 1 Inhibitor in Germinal Center-Driven Collagen-Induced Arthritis

Cynthia Louis, Devi Ngo, Damian B D'Silva, Jacinta Hansen, Louisa Phillipson, Helene Jousset, Patrizia Novello, David Segal, Kate E Lawlor, Christopher J Burns, Ian P Wicks

Journal article | 2019 | Arthritis & Rheumatology

Dysregulated IL-1-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

Man Lyang Kim, William J Martin, Gabriela Minigo, Joanne L Keeble, Alexandra L Garnham, Guido Pacini, Gordon K Smyth, Terence P Speed, Jonathan Carapetis, Ian P Wicks

Journal article | 2018 | Circulation

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface

Fiona Moghaddas, Ping Zeng, Yuxia Zhang, Heike Schuetzle, Sebastian Brenner, Sigrun R Hofmann, Reinhard Berner, Yuanbo Zhao, Bingtai Lu, Xiaoyun Chen, Li Zhang, Suyun Cheng, Stefan Winkler, Kai Lehmberg, Scott W Canna, Peter E Czabotar, Ian P Wicks, Dominic De Nardo, Christian M Hedrich, Huasong Zeng, et al.

Journal article | 2018 | Journal of Allergy and Clinical Immunology

Rheumatic immune-related adverse events secondary to anti-programmed death-1 antibodies and preliminary analysis on the impact of corticosteroids on anti-tumour response: A case series

Emma L Mitchell, Peter Kar Han Lau, Chloe Khoo, David Liew, Jessica Leung, Bonnia Liu, Adam Rischin, Albert G Frauman, Damien Kee, Kortnye Smith, Benjamin Brady, Danny Rischin, Andrew Gibson, Linda Mileshkin, Oliver Klein, Andrew Weickhardt, Surein Arulananda, Mark Shackleton, Grant McArthur, Andrew Ostor, et al.

Journal article | 2018 | European Journal of Cancer

Is establishing a specialist back pain assessment and management service in primary care a safe and effective model? Twelve-month results from the Back pain Assessment Clinic (BAC) prospective cohort pilot study

John HY Moi, Uyen Phan, Adam de Gruchy, Danny Liew, Tanya I Yuen, John E Cunningham, Ian P Wicks

Journal article | 2018 | BMJ Open

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

Andrew D Foers, Simon Chatfield, Laura F Dagley, Benjamin J Scicluna, Andrew I Webb, Lesley Cheng, Andrew F Hill, Ian P Wicks, Ken C Pang

Journal article | 2018 | Journal of Extracellular Vesicles

Information in referrals to public outpatient specialist clinics for back pain: audit results and consensus recommendations

Lauren Ross, Adam de Gruchy, Uyen M Phan, Matthew Warrender-Sparkes, Ian P Wicks, John HY Moi

Journal article | 2018 | Medical Journal of Australia

TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity

Cynthia Louis, Chris Burns, Ian Wicks

Journal article | 2018 | Frontiers in Immunology

Monosodium Urate Crystals Generate Nuclease-Resistant Neutrophil Extracellular Traps via a Distinct Molecular Pathway

Simon M Chatfield, Kathrin Grebe, Lachlan W Whitehead, Kelly L Rogers, Thomas Nebl, James M Murphy, Ian P Wicks

Journal article | 2018 | The Journal of Immunology

A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever

Fiona Moghaddas, Rafael Llamas, Dominic De Nardo, Helios Martinez-Banaclocha, Juan J Martinez-Garcia, Pablo Mesa-del-Castillo, Paul J Baker, Vanessa Gargallo, Anna Mensa-Vilaro, Scott Canna, Ian P Wicks, Pablo Pelegrin, Juan I Arostegui, Seth L Masters

Journal article | 2017 | Annals of the Rheumatic Diseases

Extracellular Vesicles in Joint Inflammation

Andrew D Foers, Lesley Cheng, Andrew F Hill, Ian P Wicks, Ken C Pang

Journal article | 2017 | Arthritis & Rheumatology

Pneumocystis jirovecii pneumonia in systemic autoimmune rheumatic disease: A case-control study

Susan Tadros, Andrew J Teichtahl, Sabina Ciciriello, Ian P Wicks

Journal article | 2017 | Seminars in Arthritis and Rheumatism

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Ian K Campbell, David Leong, Kirsten M Edwards, Veronika Rayzman, Milica Ng, Gabrielle L Goldberg, Nicholas J Wilson, Karen Scalzo-Inguanti, Charley Mackenzie-Kludas, Kate E Lawlor, Ian P Wicks, Lorena E Brown, Adriana Baz Morelli, Con Panousis, Michael J Wilson, Andrew D Nash, Brent S McKenzie, Arna E Andrews

Journal article | 2016 | The Journal of Immunology

GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease

Angus T Stock, Jacinta A Hansen, Matthew A Sleeman, Brent S McKenzie, Ian P Wicks

Journal article | 2016 | The Journal of Experimental Medicine

Atherosclerotic lesion regression is impaired in the K/BxN model of rheumatoid arthritis, independent of circulating cholesterol levels

D Dragoljevic, A Whillas, M Kraakman, D Ngo, W Shihata, S van Doornum, I Wicks, M Febbraio, J Chin-Dusting, AJ Murphy

Conference Proceedings | 2016 | EUROPEAN JOURNAL OF IMMUNOLOGY

G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis (vol 186, pg 172, 2016)

Gabrielle L Goldberg, Ann L Cornish, Jane Murphy, Ee Shan Pang, Damian B D'Silva, Lyndell L Lim, Ian K Campbell, Karen Scalzo-Inguanti, Xiangting Chen, Paul G McMenamin, Eugene Maraskovsky, Brent S McKenzie, Ian P Wicks

Journal article | 2016 | The American Journal of Pathology

A cytotoxic anti-IL-3R alpha antibody targets key cells and cytokines implicated in systemic lupus erythematosus

Shereen Oon, Huy Huynh, Tsin Yee Tai, Milica Ng, Katherine Monaghan, Mark Biondo, Gino Vairo, Eugene Maraskovsky, Andrew D Nash, Ian P Wicks, Nicholas J Wilson

Journal article | 2016 | JCI Insight

Targeted therapeutics in SLE: emerging strategies to modulate the interferon pathway

Shereen Oon, Nicholas J Wilson, Ian Wicks

Journal article | 2016 | Clinical & Translational Immunology

Suppression of inflammatory disease activity in rheumatoid arthritis is associated with improvements in retinal microvascular health

John Hsing-Yih Moi, Lauren AB Hodgson, Ian P Wicks, Tien Yin Wong, Sharon Van Doornum

Journal article | 2016 | Rheumatology

Targeting GM-CSF in inflammatory diseases

Ian P Wicks, Andrew W Roberts

Journal article | 2016 | Nature Reviews Rheumatology

G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis

Gabrielle L Goldberg, Ann L Cornish, Jane Murphy, Ee Shan Pang, Lyndell L Lim, Ian K Campbell, Karen Scalzo-Inguanti, Xiangting Chen, Paul G McMenamin, Eugene Maraskovsky, Brent S McKenzie, Ian P Wicks

Journal article | 2016 | The American Journal of Pathology

Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3

X Liu, R Liu, BA Croker, KE Lawlor, GK Smyth, IP Wicks

Journal article | 2015 | Osteoarthritis and Cartilage

Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis

DEA Greven, ES Cohen, DM Gerlag, J Campbell, J Woods, N Davis, A van Nieuwenhuijze, A Lewis, S Heasmen, M McCourt, D Corkill, A Dodd, J Elvin, G Statache, IP Wicks, IK Anderson, A Nash, MA Sleeman, PP Tak

Journal article | 2015 | Annals of the Rheumatic Diseases

Post-infectious group A streptococcal autoimmune syndromes and the heart

William John Martin, Andrew C Steer, Pierre Robert Smeesters, Joanne Keeble, Michael Inouye, Jonathan Carapetis, Ian P Wicks

Journal article | 2015 | Autoimmunity Reviews

Pneumocystis jirovecci pneumonia in connective tissue diseases: Comparison with other immunocompromised patients

Andrew J Teichtahl, Kathleen Morrisroe, Sabina Ciciriello, Ian Jennens, Susan Tadros, Ian Wicks

Journal article | 2015 | Seminars in Arthritis and Rheumatism

Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-kappa B ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis

Annemarie EM van Nieuwenhuijze, Fons A van de Loo, Birgitte Walgreen, Miranda Bennink, Monique Helsen, Liduine van den Bersselaar, Ian P Wicks, Wim B van den Berg, Marije I Koenders

Journal article | 2015 | Arthritis Research & Therapy

Bcl-2 Antagonists Kill Plasmacytoid Dendritic Cells From Lupus-Prone Mice and Dampen Interferon-alpha Production

Yifan Zhan, Emma M Carrington, Hyun-Ja Ko, Ingela B Vikstrom, Shereen Oon, Jian-Guo Zhang, David Vremec, Jamie L Brady, Philippe Bouillet, Li Wu, David CS Huang, Ian P Wicks, Eric F Morand, Andreas Strasser, Andrew M Lew

Journal article | 2015 | Arthritis & Rheumatology

Increased 30-day and 1-year mortality rates and lower coronary revascularisation rates following acute myocardial infarction in patients with autoimmune rheumatic disease

Sharon Van Doornum, Megan Bohensky, Mark A Tacey, Caroline A Brand, Vijaya Sundararajan, Ian P Wicks

Journal article | 2015 | Arthritis Research & Therapy

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E Lawlor, Nufail Khan, Alison Mildenhall, Motti Gerlic, Ben A Croker, Akshay A D'Cruz, Cathrine Hall, Sukhdeep Kaur Spall, Holly Anderton, Seth L Masters, Maryam Rashidi, Ian P Wicks, Warren S Alexander, Yasuhiro Mitsuuchi, Christopher A Benetatos, Stephen M Condon, W Wei-Lynn Wong, John Silke, David L Vaux, James E Vince

Journal article | 2015 | Nature Communications

In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression

Xiangting Chen, Jelena M Kezic, John V Forrester, Gabrielle L Goldberg, Ian P Wicks, Claude C Bernard, Paul G McMenamin

Journal article | 2015 | Journal of Neuroinflammation

Interleukin-6 In Rheumatoid Arthritis - From The Laboratory To The Bedside

Xiao Liu, Andrew J Teichtahl, Ian P Wicks

Journal article | 2015 | Current Pharmaceutical Design

Arterial stiffness is increased in systemic sclerosis: a cross-sectional comparison with matched controls

G-S Ngian, J Sahhar, IP Wicks, S Van Doornum

Journal article | 2014 | Clinical and experimental rheumatology

Synergism Between GM-CSF and IL-17 Causes Enhanced Joint Pathology Via the Production of IL-6 and IL-23

Annemarie EM van Nieuwenhuijze, Debbie M Roeleveld, Birgitte Walgreen, Miranda Bennink, Monique M Helsen, Liduine van den Bersselaar, Ian P Wicks, Wim B van den Berg, Fons A van de Loo, Marije I Koenders

Conference Proceedings | 2014 | ARTHRITIS & RHEUMATOLOGY

Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine-Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis

Xiao Liu, Ben A Croker, Ian K Campbell, Stephanie J Gauci, Warren S Alexander, Brett A Tonkin, Nicole C Walsh, Edmond M Linossi, Sandra E Nicholson, Kate E Lawlor, Ian P Wicks

Journal article | 2014 | Arthritis & Rheumatology

Infection Mobilizes Hematopoietic Stem Cells through Cooperative NOD-like Receptor and Toll-like Receptor Signaling

Aaron Burberry, Melody Y Zeng, Lei Ding, Ian Wicks, Naohiro Inohara, Sean J Morrison, Gabriel Nunez

Journal article | 2014 | Cell Host & Microbe

SYNERGISM BETWEEN GM-CSF AND IL-17 CAUSES ENHANCED JOINT PATHOLOGY VIA THE PRODUCTION OF IL-6 AND IL-23

AE van Nieuwenhuijze, DM Roeleveld, B Walgreen, MM Helsen, L van den Bersselaar, IP Wicks, WB van den Berg, FA van de Loo, MI Koenders

Conference Proceedings | 2014 | Annals of the Rheumatic Diseases

Improving treatment with methotrexate in rheumatoid arthritis-Development of a multimedia patient education program and the MiRAK, a new instrument to evaluate methotrexate-related knowledge

Sabina Ciciriello, Rachelle Buchbinder, Richard H Osborne, Ian P Wicks

Journal article | 2014 | Seminars in Arthritis and Rheumatism

Transgenic Expression of GM-CSF in T Cells Causes Disseminated Histiocytosis

Annemarie E van Nieuwenhuijze, Elise Coghill, Daniel Gray, Sandro Prato, Donald Metcalf, Warren S Alexander, Ian P Wicks

Journal article | 2014 | American Journal of Pathology

Statin initiation and treatment non-adherence following a first acute myocardial infarction in patients with inflammatory rheumatic disease versus the general population

Megan Bohensky, Mark Tacey, Caroline Brand, Vijaya Sundararajan, Ian Wicks, Sharon Van Doornum

Journal article | 2014 | Arthritis Research & Therapy

GM-CSF as a therapeutic target in inflammatory diseases

Annemarie van Nieuwenhuijze, Marije Koenders, Debbie Roeleveld, Matthew A Sleeman, Wim van den Berg, Ian P Wicks

Journal article | 2013 | Molecular Immunology

Suppressor Of Cytokine Signaling-3 Is a Critical Regulator Of gp130 Cytokine Signaling In Articular Chondrocytes

Xiao Liu, Kate E Lawlor, Ben A Croker, Ian P Wicks

Conference Proceedings | 2013 | ARTHRITIS AND RHEUMATISM

Synergism Between Granulocyte-Macrophage Colony Stimulating Factor and Interleukin-17 Causes Joint Damage Via The Production Of Interleukin-23, Receptor Activator Of NF-kappa B Ligand and S100A8

Annemarie EM Van Nieuwenhuijze, Fons AJ Van de Loo, Birgitte Walgreen, Miranda B Bennink, Monique M Helsen, Liduine Van den Bersselaar, Ian P Wicks, Wim B Van den Berg, Marije I Koenders

Conference Proceedings | 2013 | ARTHRITIS AND RHEUMATISM

Comparison Of Medication Usage Following Myocardial Infarction In Patients With Autoimmune Rheumatic Disease Versus Controls

Sharon Van Doornum, Mark Tacey, Megan Bohensky, Caroline Brand, Vijaya Sundararajan, Ian Wicks

Conference Proceedings | 2013 | ARTHRITIS AND RHEUMATISM

Mortality Rates, Readmissions and Revascularisation Following a First Myocardial Infarction In Patients With Autoimmune Rheumatic Disease Compared With Controls.

Sharon Van Doornum, Megan Bohensky, Mark Tacey, Caroline Brand, Vijaya Sundararajan, Ian Wicks

Conference Proceedings | 2013 | ARTHRITIS AND RHEUMATISM

Primary angiitis of the central nervous system: experience of a Victorian tertiary-referral hospital

S Oon, C Roberts, A Gorelik, I Wicks, C Brand

Journal article | 2013 | Internal Medicine Journal

LIVE CELL IMAGING OF HUMAN NEUTROPHIL RESPONSES TO MSU CRYSTALS

S Chatfield, B McKenzie, I Wicks

Journal article | 2013 | Annals of the Rheumatic Diseases

Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering Fc gamma RIIb expression and monocyte homeostasis

Kate E Lawlor, Annemarie van Nieuwenhuijze, Karen L Parker, Sarah F Drake, Ian K Campbell, Scott D Smith, James E Vince, Andreas Strasser, Ian P Wicks

Journal article | 2013 | Journal of Leukocyte Biology

Multimedia educational interventions for consumers about prescribed and over-the-counter medications

Sabina Ciciriello, Renea V Johnston, Richard H Osborne, Ian Wicks, Tanya deKroo, Rosemary Clerehan, Clare O'Neill, Rachelle Buchbinder

Journal article | 2013 | Cochrane Database of Systematic Reviews

Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis

Gene-Siew Ngian, Joanne Sahhar, Susanna M Proudman, Wendy Stevens, Ian P Wicks, Sharon Van Doornum

Journal article | 2012 | Annals of the Rheumatic Diseases

Arterial Stiffness Is Increased in Systemic Sclerosis: A Cross-Sectional Comparison with Matched Controls.

Gene-Siew Ngian, Joanne Sahhar, Ian Wicks, Sharon Van Doornum

Conference Proceedings | 2012 | ARTHRITIS AND RHEUMATISM

TRANSGENIC OVER-EXPRESSION OF GM-CSF IN T CELLS CAUSES HISTIOCYTOSIS

A Van Nieuwenhuijze, E Coghill, W Alexander, D Gray, I Wicks

Journal article | 2012 | INTERNAL MEDICINE JOURNAL

SOCS-3 IS A CRITICAL REGULATOR OF GP130 CYTOKINE SIGNALLING IN ARTICULAR CHONDROCYTES

X Liu, B Croker, K Lawlor, I Wicks

Journal article | 2012 | INTERNAL MEDICINE JOURNAL

Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis

G NGIAN, J Sahhar, SM Proudman, W Stevens, IP Wicks, S Van Doornum

Journal article | 2012 | Annals of the Rheumatic Diseases

Evaluation of the Bcl-2 family antagonist ABT-737 in collagen-induced arthritis

Kate E Lawlor, Scott D Smith, Annemarie van Nieuwenhuijze, David CS Huang, Ian P Wicks

Journal article | 2011 | Journal of Leukocyte Biology

GM-CSF increases cross-presentation and CD103 expression by mouse CD8( ) spleen dendritic cells

Yifan Zhan, Emma M Carrington, Annemarie van Nieuwenhuijze, Sammy Bedoui, Shirley Seah, Yuekang Xu, Nancy Wang, Justine D Mintern, Jose A Villadangos, Ian P Wicks, Andrew M Lew

Journal article | 2011 | European Journal of Immunology

Defects in the Bcl-2-Regulated Apoptotic Pathway Lead to Preferential Increase of CD25(low)Foxp3( ) Anergic CD4( ) T Cells

Yifan Zhan, Yuxia Zhang, Daniel Gray, Emma M Carrington, Philippe Bouillet, Hyun-Ja Ko, Lorraine O'Reilly, Ian P Wicks, Andreas Strasser, Andrew M Lew

Journal article | 2011 | Journal of Immunology

ANTI-INFLAMMATORY EFFECTS OF HAEMATOPOIETIC OVER-EXPRESSION OF BCL-2 IN EXPERIMENTAL ARTHRITIS

K Lawlor, A Van Nieuwenhuijze, K Parker, S Drake, I Campbell, S Smith, A Strasser, I Wicks

Journal article | 2011 | INTERNAL MEDICINE JOURNAL

Differentiation of Inflammatory Dendritic Cells Is Mediated by NF-kappa B1-Dependent GM-CSF Production in CD4 T Cells

Ian K Campbell, Annemarie van Nieuwenhuijze, Elodie Segura, Kristy O'Donnell, Elise Coghill, Mirja Hommel, Steve Gerondakis, Jose A Villadangos, Ian P Wicks

Journal article | 2011 | Journal of Immunology

Retinal vascular calibre is altered in patients with rheumatoid arthritis: a biomarker of disease activity and cardiovascular risk?

Sharon Van Doornum, Gemma Strickland, Ryo Kawasaki, Jing Xie, Ian P Wicks, Lauren AB Hodgson, Tien Y Wong

Journal article | 2011 | Rheumatology

Cardiovascular disease in systemic sclerosis - an emerging association?

Gene-Siew Ngian, Joanne Sahhar, Ian P Wicks, Sharon Van Doornum

Journal article | 2011 | Arthritis Research & Therapy

Regulation of interleukin-1 beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

Seth L Masters, Lisa A Mielke, Ann L Cornish, Caroline E Sutton, Joanne O'Donnell, Louise H Cengia, Andrew W Roberts, Ian P Wicks, Kingston HG Mills, Ben A Croker

Journal article | 2010 | EMBO Reports

Reply to Burgdorf et al.: The mannose receptor is not involved in antigen cross-presentation by steady-state dendritic cells

Elodie Segura, Nishma Gupta, Anthony L Albiston, Ian P Wicks, Siew Yeen Chai, Jose A Villadangos

Journal article | 2010 | Proceedings of the National Academy of Sciences

Rheumatoid arthritis patients receive less frequent acute reperfusion and secondary prevention therapy after myocardial infarction compared with the general population

Sharon Van Doornum, Caroline Brand, Vijaya Sundararajan, Andrew E Ajani, Ian P Wicks

Journal article | 2010 | Arthritis Research & Therapy

Different cross-presentation pathways in steady-state and inflammatory dendritic cells

Elodie Segura, Anthony L Albiston, Ian P Wicks, Siew Yeen Chai, Jose A Villadangos

Journal article | 2009 | Proceedings of the National Academy of Sciences of the United States of America

Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress.

AH Iyo, N Kieran, A Chandran, PR Albert, I Wicks, G Bissette, MC Austin

Journal article | 2009 | Neuroscience

Chronic stress is known to affect brain areas involved in learning and emotional responses. These changes, thought to be related t..

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

Ann L Cornish, Ian K Campbell, Brent S McKenzie, Simon Chatfield, Ian P Wicks

Journal article | 2009 | Nature Reviews Rheumatology

Administered G-CSF boosts low affinity antibody production during T cell-dependent responses

Ann L Cornish, Jo L Eyles, Jane Murphy, Sarah F Drake, Donald Metcalf, Andrew W Roberts, David M Tarlinton, Ian P Wicks

Conference Proceedings | 2009 | Cytokine

Anti-citrullinated peptide antibody: death of the rheumatoid factor?

Simon M Chatfield, Ian P Wicks, Allan D Sturgess, Lynden J Roberts

Journal article | 2009 | Medical Journal of Australia

Autoimmune Regulator Controls T Cell Help for Pathogenetic Autoantibody Production in Collagen-Induced Arthritis

Ian K Campbell, Sarah A Kinkel, Sarah F Drake, Annemarie van Nieuwenhuijze, Francois-Xavier Hubert, David M Tarlinton, William R Heath, Hamish S Scott, Ian P Wicks

Journal article | 2009 | Arthritis and Rheumatism

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis

Jo L Eyles, Michael J Hickey, M Ursula Norman, Ben A Croker, Andrew W Roberts, Sarah F Drake, Will G James, Donald Metcalf, Ian K Campbell, Ian P Wicks

Journal article | 2008 | Blood

Promotion of the Local Differentiation of Murine Th17 Cells by Synovial Macrophages During Acute Inflammatory Arthritis

Paul J Egan, Annemarie van Nieuwenhuijze, Ian K Campbell, Ian P Wicks

Journal article | 2008 | Arthritis & Rheumatism

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis

H Patrick McNeil, Kichul Shin, Ian K Campbell, Ian P Wicks, Roberto Adachi, David M Lee, Richard L Stevens

Journal article | 2008 | Arthritis & Rheumatism

G-CSF induces leukocyte recruitment in vivo via the leukocyte G-CSF receptor

Michael Hickey, M Ursula Norman, Ben Croker, Andrew Roberts, Ian Wicks, Jo Eyles

Journal article | 2008 | FASEB JOURNAL

Experienced physiotherapists as gatekeepers to hospital orthopaedic outpatient care

Caroline A Brand, Richard H Osborne, Ian P Wicks, Richard N de Steiger

Journal article | 2008 | Medical Journal of Australia

Prevalence and cost of musculoskeletal disorders: A population-based, public hospital system healthcare consumption approach

Richard H Osborne, Mandana Nikpour, Lucy Busija, Vijaya Sundararajan, Ian P Wicks

Journal article | 2007 | Journal of Rheumatology

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Benjamin T Kile, Athanasia D Panopoulos, Roslynn A Stirzaker, Douglas F Hacking, Lubna H Tahtamouni, Tracy A Willson, Lisa A Mielke, Katya J Henley, Jian-Guo Zhang, Ian P Wicks, William S Stevenson, Paquita Nurden, Stephanie S Watowich, Monica J Justice

Journal article | 2007 | Blood

The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

Kristy Boyle, Paul Egan, Steven Rakar, Tracy A Willson, Ian P Wicks, Donald Metcalf, Douglas J Hilton, Nicos A Nicola, Warren S Alexander, Andrew W Roberts, Lorraine Robb

Journal article | 2007 | Blood

Prevalence and cost of musculoskeletal disorders: a population-based, public hospital system healthcare consumption approach.

R Osborne, undefined Nikpour, L Busija, undefined Sundarajan, IP Wicks

Journal article | 2007 | Journal of Rheumatology

Prevalence and cost of musculoskeletal disorders.

Richard H Osborne, Mandana Nikpour, Lucy Busija, Ian P Wicks

Conference Proceedings | 2006 | ARTHRITIS AND RHEUMATISM

Granulocyte colony-stimulating factor and neutrophils - forgotten mediators of inflammatory disease

Jo L Eyles, Andrew W Roberts, Donald Metcalf, Ian P Wicks

Journal article | 2006 | Nature Clinical Practice Rheumatology

Prioritization for hip and knee joint replacement surgery (JRS): A new system that assigns queue position to get the right person to the right care at the right time.

Richard H Osborne, Kerry Haynes, Caroline Brand, Paul A Dieppe, Ian P Wicks, Stephen E Graves

Conference Proceedings | 2006 | ARTHRITIS AND RHEUMATISM

SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis

Peter KK Wong, Paul J Egan, Ben A Croker, Kristy O'Donnell, Natalie A Sims, Sarah Drake, Hiu Kiu, Edward J McManus, Warren S Alexander, Andrew W Roberts, Ian P Wicks

Journal article | 2006 | Journal of Clinical Investigation

Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

Shalin H Naik, Donald Metcalf, Annemarie Van Nieuwenhuijze, Ian Wicks, Li Wu, Meredith O'Keeffe, Ken Shortman

Journal article | 2006 | Nature Immunology

Reducing the cardiovascular disease burden in rheumatoid arthritis

S Van Doornum, GLR Jennings, IP Wicks

Journal article | 2006 | Medical Journal of Australia

Interleukin-6 modulates production of T lymphocyte-derived cytokines in antigen-induced arthritis and drives inflammation-induced osteoclastogenesis

PKK Wong, JMW Quinn, NA Sims, A van Nieuwenhuijze, IK Campbell, IP Wicks

Journal article | 2006 | Arthritis and Rheumatism

Acute CD4 T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor

KE Lawlor, PKK Wong, IK Campbell, N van Rooijen, IP Wicks

Journal article | 2005 | Arthritis & Rheumatism

G-CSF is a pathogenic mediator of inflammatory arthritis in mice

KE Lawlor, IK Campbell, D Metcalf, AW Roberts, IP Wicks

Journal article | 2005 | IMMUNOLOGY

Essential role of NF-kappaB1 (p50) for CD4 T cell function in IL-1 dependent acute inflammatory arthritis

IK Campbell, K O'Donnell, S Gerondakis, A Van Nieuwenhuijze, IP Wicks

Conference Proceedings | 2005 | TISSUE ANTIGENS

Inflammatory status guides dendritic cell development from different precursors

SH Naik, D Metcalf, A Van Nieuwenhuijze, IP Wicks, L Wu, M O'Keeffe, K Shortman

Conference Proceedings | 2005 | TISSUE ANTIGENS

Suppressor of cytokine signalling-3 (SOCS3) negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis

PKK Wong, PJ Egan, BA Croker, K O'Donnell, WS Alexander, AW Roberts, IP Wicks

Conference Proceedings | 2005 | TISSUE ANTIGENS

A critical role for granulocyte colony stimulating factor (G-CSF) and neutrophils during inflammatory arthritis

JL Eyles, IK Campbell, IP Wicks

Conference Proceedings | 2005 | TISSUE ANTIGENS

Tumour necrosis factor antagonists improve disease activity but not arterial stiffness in rheumatoid arthritis

S Van Doornum, G McColl, IP Wicks

Journal article | 2005 | RHEUMATOLOGY

Severely compromised quality of life in women and those of lower socioeconomic status waiting for joint replacement surgery

IN Ackerman, SE Graves, IP Wicks, KL Bennell, RH Osborne

Journal article | 2005 | ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH

Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fc gamma receptor IIa-transgenic mice

CT Sardjono, PL Mottram, NC van de Velde, MS Powell, D Power, RF Slocombe, IP Wicks, IK Campbell, SE McKenzie, M Brooks, AW Stevenson, PM Hogarth

Journal article | 2005 | Arthritis and Rheumatism

Sustained remission, possibly cure, of seronegative arthritis after high-dose chemotherapy and syngeneic hematopoietic stem cell transplantation

GJ McColl, J Szer, IP Wicks

Journal article | 2005 | Arthritis and Rheumatism