Graham Giles

A Simple Clinical Tool for Stratifying Risk of Clinically Significant CKD after Nephrectomy: Development and Multinational Validation.

Robert J Ellis, Sharon J Del Vecchio, Kevin MJ Gallagher, Danielle N Aliano, Neil Barber, Damien M Bolton, Etienne TS Chew, Jeff S Coombes, Michael D Coory, Ian D Davis, James F Donaldson, Ross S Francis, Graham G Giles, Glenda C Gobe, Carmel M Hawley, David W Johnson, Alexander Laird, Steve Leung, Manar Malki, David JT Marco, et al.

Journal article  |  2020  |  Journal of the American Society of Nephrology

BACKGROUND: Clinically significant CKD following surgery for kidney cancer is associated with increased morbidity and mortality, b..

Mismatch repair gene pathogenic germline variants in a population-based cohort of breast cancer

Tu Nguyen-Dumont, Jason A Steen, Ingrid Winship, Daniel J Park, Bernard J Pope, Fleur Hammet, Maryam Mahmoodi, Helen Tsimiklis, Derrick Theys, Mark Clendenning, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2020  |  Familial Cancer

The advent of gene panel testing is challenging the previous practice of using clinically defined cancer family syndromes to infor..

The role of renal mass biopsy in the management of small renal masses - patterns of use and surgeon opinion

Melinda M Protani, Andre Joshi, Victoria White, David JT Marco, Rachel E Neale, Michael D Coory, Graham G Giles, Damien M Bolton, Ian D Davis, Simon Wood, Susan J Jordan

Journal article  |  2020  |  Journal of Clinical Urology

Aims: Renal mass biopsy (RMB) is advocated to improve management of small renal masses, however there is concern about its clinica..

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R Barnes, Jamie Allen, Siddhartha Kar, Karen A Pooley, Joe Dennis, Kyriaki Michailidou, Constance Turman, Penny Soucy, Audrey Lemacon, Michael Lush, Jonathan P Tyrer, Maya Ghoussaini, Mahdi Moradi Marjaneh, Xia Jiang, Simona Agata, Kristiina Aittomaki, M Rosario Alonso, et al.

Journal article  |  2020  |  Nature Genetics

Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underl..

Childhood pneumonia, pleurisy and lung function: a cohort study from the first to sixth decade of life

Jennifer L Perret, Caroline J Lodge, Adrian J Lowe, David P Johns, Bruce R Thompson, Dinh S Bui, Lyle C Gurrin, Melanie C Matheson, Christine F McDonald, Richard Wood-Baker, Cecilie Svanes, Paul S Thomas, Graham G Giles, Anne B Chang, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage, Heather Gibson, Bryan Gandevia, Harold Silverstone, et al.

Journal article  |  2020  |  Thorax

INTRODUCTION: Adult spirometry following community-acquired childhood pneumonia has variably been reported as showing obstructive ..

Social connectedness and mortality after prostate cancer diagnosis: A prospective cohort study

Zimu Wu, Nga H Nguyen, Dawei Wang, Brigid M Lynch, Allison M Hodge, Julie K Bassett, Victoria M White, Ron Borland, Dallas R English, Roger L Milne, Graham G Giles, Pierre-Antoine Dugue

Journal article  |  2019  |  International Journal of Cancer

Men with prostate cancer experience side effects for which a supportive social environment may be beneficial. We examined the asso..

Body size and dietary risk factors for aggressive prostate cancer: a case-control study

Mikaela Pal, Allison M Hodge, Nathan Papa, Robert J MacInnis, Julie K Bassett, Damien Bolton, Ian D Davis, Jeremy Millar, Dallas R English, John L Hopper, Gianluca Severi, Melissa C Southey, Roger L Milne, Graham G Giles

Journal article  |  2019  |  Cancer Causes & Control

PURPOSE: Diet and body size may affect the risk of aggressive prostate cancer (APC), but current evidence is inconclusive. METHODS..

Accuracy of Risk Estimates from the iPrevent Breast Cancer Risk Assessment and Management Tool

Kelly-Anne Phillips, Yuyan Liao, Roger L Milne, Robert J MacInnis, Ian M Collins, Richard Buchsbaum, Prue C Weideman, Adrian Bickerstaffe, Stephanie Nesci, Wendy K Chung, Melissa C Southey, Julia A Knight, Alice S Whittemore, Gillian S Dite, David Goldgar, Graham G Giles, Gord Glendon, Jack Cuzick, Antonis C Antoniou, Irene L Andrulis, et al.

Journal article  |  2019  |  JNCI Cancer Spectrum

Background: iPrevent is an online breast cancer (BC) risk management decision support tool. It uses an internal switching algorith..

Alcohol consumption, cigarette smoking, and familial breast cancer risk: findings from the Prospective Family Study Cohort (ProF-SC)

Nur Zeinomar, Julia A Knight, Jeanine M Genkinger, Kelly-Anne Phillips, Mary B Daly, Roger L Milne, Gillian S Dite, Rebecca D Kehm, Yuyan Liao, Melissa C Southey, Wendy K Chung, Graham G Giles, Sue-Anne McLachlan, Michael L Friedlander, Prue C Weideman, Gord Glendon, Stephanie Nesci, Irene L Andrulis, Saundra S Buys, Esther M John, et al.

Journal article  |  2019  |  Breast Cancer Research

BACKGROUND: Alcohol consumption and cigarette smoking are associated with an increased risk of breast cancer (BC), but it is uncle..

Development and validation of a targeted gene sequencing panel for application to disparate cancers

Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, undefined kConFab, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, et al.

Journal article  |  2019  |  Scientific Reports

Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology ..

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna Kiiski, Taru A Muranen, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Manjeet K Bolla, Goska Leslie, Cora M Aalfs, Muriel A Adank, Julian Adlard, Simona Agata, Karen Cadoo, Bjarni A Agnarsson, Thomas Ahearn, et al.

Journal article  |  2019  |  npj Breast Cancer

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1..

Homologous recombination DNA repair defects in PALB2-associated breast cancers

Anqi Li, Felipe C Geyer, Pedro Blecua, Ju Youn Lee, Pier Selenica, David N Brown, Fresia Pareja, Simon SK Lee, Rahul Kumar, Barbara Rivera, Rui Bi, Salvatore Piscuoglio, Hannah Y Wen, John R Lozada, Rodrigo Gularte-Merida, Luca Cavallone, Zoulikha Rezoug, Tu Nguyen-Dumont, Paolo Peterlongo, Carlo Tondini, et al.

Journal article  |  2019  |  npj Breast Cancer

Benign breast disease increases breast cancer risk independent of underlying familial risk profile: Findings from a Prospective Family Study Cohort

Nur Zeinomar, Kelly-Anne Phillips, Mary B Daly, Roger L Milne, Gillian S Dite, Robert J MacInnis, Yuyan Liao, Rebecca D Kehm, Julia A Knight, Melissa C Southey, Wendy K Chung, Graham G Giles, Sue-Anne McLachlan, Michael L Friedlander, Prue C Weideman, Gord Glendon, Stephanie Nesci, Irene L Andrulis, Saundra S Buys, Esther M John, et al.

Journal article  |  2019  |  International Journal of Cancer

Smoking is associated with risks of molecular subtypes of colorectal cancer

Xiaoliang Wang, Efrat Amitay, Barbara L Banbury, Hermann Brenner, Daniel D Buchanan, Peter T Campbell, Jenny Chang-Claude, Steven J Gallinger, Graham G Giles, Tabitha A Harrison, John L Hopper, Mark A Jenkins, Yi Lin, Reiko Nishihara, Polly A Newcomb, Shuji Ogino, Lori C Sakoda, Robert E Schoen, Martha L Slattery, Steven N Thibodeau, et al.

Conference Proceedings  |  2019  |  Epidemiology

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (vol 138, pg 307, 2019)

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

Occupational exposure to solvents and lung function decline: A population based study

Sheikh M Alif, Shyamali Dharmage, Geza Benke, Martine Dennekamp, John Burgess, Jennifer L Perret, Caroline Lodge, Stephen Morrison, David Peter Johns, Graham Giles, Lyle Gurrin, Paul S Thomas, John Llewelyn Hopper, Richard Wood-Baker, Bruce Thompson, Iain Feather, Roel Vermeulen, Hans Kromhout, Debbie Jarvis, Judith Garcia Aymerich, et al.

Journal article  |  2019  |  Thorax

The Use of Optimal Treatment for DLBCL Is Improving in All Age Groups and Is a Key Factor in Overall Survival, but Non-Clinical Factors Influence Treatment

Nicole Wong Doo, Victoria M White, Kara Martin, Julie K Bassett, H Miles Prince, Simon J Harrison, Michael Jefford, Ingrid Winship, Jeremy L Millar, Roger L Milne, John F Seymour, Graham G Giles

Journal article  |  2019  |  Cancers

INTRODUCTION: Diffuse large B cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma for which a cure is usually the ..

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

Xiang Shu, Lang Wu, Nikhil K Khankari, Xiao-Ou Shu, Thomas J Wang, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Roger L Milne, Marjanka K Schmidt, Paul DP Pharoah, Irene L Andrulis, David J Hunter, Jacques Simard, Douglas F Easton, Wei Zheng, Beeghly-Fadiel J Alicia, Hoda Anton-Culver, Natalia N Antonenkova, et al.

Journal article  |  2019  |  International Journal of Epidemiology

Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circula..

Incident Chronic Kidney Disease After Radical Nephrectomy for Renal Cell Carcinoma

Robert J Ellis, Victoria M White, Damien M Bolton, Michael D Coory, Ian D Davis, Ross S Francis, Graham G Giles, Glenda C Gobe, David JT Marco, Rachel E Neale, Simon T Wood, Susan J Jordan, Graham Giles, Victoria White, Michael Coory, Jeremy Millar, Damien Bolton, Ian Davis, Ingrid Winship, Ian Roos, et al.

Journal article  |  2019  |  Clinical Genitourinary Cancer

Dietary Intake of Nutrients Involved in One-Carbon Metabolism and Risk of Gastric Cancer: A Prospective Study

Pierre-Antoine Dugue, Julie K Bassett, Maree T Brinkman, Melissa C Southey, Jihoon E Joo, Ee Ming Wong, Roger L Milne, Dallas R English, Graham G Giles, Alex Boussioutas, Hazel Mitchell, Allison M Hodge

Journal article  |  2019  |  Nutrition and Cancer

Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study

Rebecca D Kehm, John L Hopper, Esther M John, Kelly-Anne Phillips, Robert J MacInnis, Gillian S Dite, Roger L Milne, Yuyan Liao, Nur Zeinomar, Julia A Knight, Melissa C Southey, Linda Vahdat, Naomi Kornhauser, Tessa Cigler, Wendy K Chung, Graham G Giles, Sue-Anne McLachlan, Michael L Friedlander, Prue C Weideman, Gord Glendon, et al.

Journal article  |  2019  |  Breast Cancer Research

Circulating concentrations of B group vitamins and urothelial cell carcinoma

Julie K Bassett, Maree T Brinkman, Pierre-Antoine Dugue, Per M Ueland, Oivind Midttun, Arve Ulvik, Damien Bolton, Melissa C Southey, Dallas R English, Roger L Milne, Allison M Hodge, Graham G Giles

Journal article  |  2019  |  International Journal of Cancer

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Manuel A Ferreira, Eric R Gamazon, Fares Al-Ejeh, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Adalgeir Arason, Volker Arndt, Kristan J Aronson, Banu K Arun, Ella Asseryanis, Jacopo Azzollini, Judith Balmana, Daniel R Barnes, Daniel Barrowdale, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Katarzyna Bialkowska, et al.

Journal article  |  2019  |  Nature Communications

Assessing the ProMCol classifier as a prognostic marker for non-metastatic colorectal cancer within the Melbourne Collaborative Cohort Study

Jihoon E Joo, Harindra Jayasekara, Ee Ming Wong, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Mark A Jenkins, John L Hopper, Dallas R English, Roger L Milne, Graham G Giles, Melissa C Southey, Daniel D Buchanan

Journal article  |  2019  |  Gut

Lifetime alcohol intake and pancreatic cancer incidence and survival: findings from the Melbourne Collaborative Cohort Study

Harindra Jayasekara, Dallas R English, Allison M Hodge, Robin Room, John L Hopper, Roger L Milne, Graham G Giles, Robert J MacInnis

Journal article  |  2019  |  Cancer Causes & Control

10-year performance of four models of breast cancer risk:a validation study

Mary Beth Terry, Yuyan Liao, Alice S Whittemore, Nicole Leoce, Richard Buchsbaum, Nur Zeinotnar, Gillian S Dite, Wendy K Chung, Julia A Knight, Melissa C Southey, Roger L Milne, David Goldgar, Graham G Giles, Sue-Anne McLachlan, Michael L Friedlander, Prue C Weideman, Gord Glendon, Stephanie Nesci, Irene L Andrulis, Esther M John, et al.

Journal article  |  2019  |  The Lancet Oncology

Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians

Christine E McLaren, Wen-Pin Chen, Nadine A Bertalli, Martin B Delatycki, Graham G Giles, Dallas R English, John L Hopper, Katrina J Allen, Lyle C Gurrin

Journal article  |  2019  |  PLOS ONE

Genome-wide association study of germline variants and breast cancer-specific mortality

Maria Escala-Garcia, Qi Guo, Thilo Doerk, Sander Canisius, Renske Keeman, Joe Dennis, Jonathan Beesley, Julie Lecarpentier, Manjeet K Bolla, Qin Wang, Jean Abraham, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Paul L Auer, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Leslie Bernstein, et al.

Journal article  |  2019  |  British Journal of Cancer

Risk-Reducing Oophorectomy and Breast Cancer Risk Across the Spectrum of Familial Risk

Mary Beth Terry, Mary B Daly, Kelly Anne Phillips, Xinran Ma, Nur Zeinomar, Nicole Leoce, Gillian S Dite, Robert J MacInnis, Wendy K Chung, Julia A Knight, Melissa C Southey, Roger L Milne, David Goldgar, Graham G Giles, Prue C Weideman, Gord Glendon, Richard Buchsbaum, Irene L Andrulis, Esther M John, Saundra S Buys, et al.

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Early-life exposure to sibling modifies the relationship between CD14 polymorphisms and allergic sensitization

Melisa YZ Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline J Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Graham Giles, Bruce R Thompson, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Katrina J Allen, Geza Benke, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, et al.

Journal article  |  2019  |  Clinical & Experimental Allergy

Coffee, tea, and caffeine intake and amyotrophic lateral sclerosis mortality in a pooled analysis of eight prospective cohort studies

J Petimar, E O'Reilly, H-O Adami, PA van den Brandt, J Buring, DR English, DM Freedman, GG Giles, N Hakansson, T Kurth, SC Larsson, K Robien, LJ Schouten, E Weiderpass, A Wolk, SA Smith-Warner

Journal article  |  2019  |  European Journal of Neurology

Physical Activity, Television Viewing Time, and DNA Methylation in Peripheral Blood

Eline H van Roekel, Pierre-Antoine Dugue, Chol-Hee Jung, Jihoon E Joo, Enes Makalic, Ee Ming Wong, Dallas R English, Melissa C Southey, Graham G Giles, Brigid M Lynch, Roger L Milne

Journal article  |  2019  |  Medicine & Science in Sports & Exercise

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

Yaohua Yang, Lang Wu, Xiang Shu, Yingchang Lu, Xiao-Ou Shu, Qiuyin Cai, Alicia Beeghly-Fadiel, Bingshan Li, Fei Ye, Andrew Berchuck, Hoda Anton-Culver, Susana Banerjee, Javier Benitez, Line Bjorge, James D Brenton, Ralf Butzow, Ian G Campbell, Jenny Chang-Claude, Kexin Chen, Linda S Cook, et al.

Journal article  |  2019  |  Cancer Research

Inference about causation between body mass index and DNA methylation in blood from a twin family study

Shuai Li, Ee Ming Wong, Minh Bui, Tuong L Nguyen, Ji-Hoon Eric Joo, Jennifer Stone, Gillian S Dite, Pierre-Antoine Dugue, Roger L Milne, Graham G Giles, Richard Saffery, Melissa C Southey, John L Hopper

Journal article  |  2019  |  International Journal of Obesity

Shared heritability and functional enrichment across six solid cancers

Xia Jiang, Hilary K Finucane, Fredrick R Schumacher, Stephanie L Schmit, Jonathan P Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B Kuchenbaecker, Joe Dennis, David V Conti, Graham Casey, Mia M Gaudet, Jeroen R Huyghe, Demetrius Albanes, Melinda C Aldrich, Angeline S Andrew, Irene L Andrulis, Hoda Anton-Culver, Antonis C Antoniou, et al.

Journal article  |  2019  |  Nature Communications

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Nasim Mavaddat, Kyriaki Michailidou, Joe Dennis, Michael Lush, Laura Fachal, Andrew Lee, Jonathan P Tyrer, Ting-Huei Chen, Qin Wang, Manjeet K Bolla, Xin Yang, Muriel A Adank, Thomas Ahearn, Kristiina Aittomaki, Jamie Allen, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Volker Arndt, Kristan J Aronson, et al.

Journal article  |  2019  |  The American Journal of Human Genetics

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study

Charleen D Adams, Rebecca Richmond, Diana L Santos Ferreira, Wes Spiller, Vanessa Tan, Jie Zheng, Peter Wurtz, Jenny Donovan, Freddie Hamdy, David Neal, J Athene Lane, George Davey Smith, Caroline Relton, Rosalind A Eeles, Christopher A Haiman, ZSofia Kote-Jarai, Fredrick R Schumacher, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, et al.

Journal article  |  2019  |  Cancer Epidemiology Biomarkers & Prevention

Tumor size and postoperative kidney function following radical nephrectomy

Robert J Ellis, Victoria M White, Damien M Bolton, Michael D Coory, Ian D Davis, Ross S Francis, Graham G Giles, Glenda C Gobe, Rachel E Neale, Simon T Wood, Susan J Jordan

Journal article  |  2019  |  Clinical Epidemiology

Breast Cancer Risk After Recent Childbirth A Pooled Analysis of 15 Prospective Studies

Hazel B Nichols, Minouk J Schoemaker, Jianwen Cai, Jiawei Xu, Lauren B Wright, Mark N Brook, Michael E Jones, Hans-Olov Adami, Laura Baglietto, Kimberly A Bertrand, William J Blot, Marie-Christine Boutron-Ruault, Miren Dorronsoro, Laure Dossus, A Heather Eliassen, Graham G Giles, Inger T Gram, Susan E Hankinson, Judy Hoffman-Bolton, Rudolf Kaaks, et al.

Journal article  |  2019  |  Annals of Internal Medicine

Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen R Huyghe, Stephanie A Bien, Tabitha A Harrison, Hyun Min Kang, Sai Chen, Stephanie L Schmit, David V Conti, Conghui Qu, Jihyoun Jeon, Christopher K Edlund, Peyton Greenside, Michael Wainberg, Fredrick R Schumacher, Joshua D Smith, David M Levine, Sarah C Nelson, Nasa A Sinnott-Armstrong, Demetrius Albanes, M Henar Alonso, Kristin Anderson, et al.

Journal article  |  2019  |  Nature Genetics

Adiposity and estrogen receptor-positive, postmenopausal breast cancer risk: Quantification of the mediating effects of fasting insulin and free estradiol.

S Ghazaleh Dashti, Julie A Simpson, Amalia Karahalios, Vivian Viallon, Margarita Moreno-Betancur, Lyle C Gurrin, Robert J MacInnis, Brigid M Lynch, Laura Baglietto, Howard A Morris, Marc J Gunter, Pietro Ferrari, Roger L Milne, Graham G Giles, Dallas R English

Journal article  |  2019  |  International Journal of Cancer

Adiposity increases estrogen receptor (ER)-positive postmenopausal breast cancer risk. While mechanisms underlying this relationsh..

Predicting interval and screen-detected breast cancers from mammographic density defined by different brightness thresholds

Tuong L Nguyen, Ye K Aung, Shuai Li, Ho Trinh Nhut, Christopher F Evans, Laura Baglietto, Kavitha Krishnan, Gillian S Dite, Jennifer Stone, Dallas R English, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, John L Hopper

Journal article  |  2018  |  Breast Cancer Research

Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)

Tricia L Larose, Florence Guida, Anouar Fanidi, Arnulf Langhammer, Kristian Kveem, Victoria L Stevens, Eric J Jacobs, Stephanie A Smith-Warner, Edward Giovannucci, Demetrius Albanes, Stephanie J Weinstein, Neal D Freedman, Ross Prentice, Mary Pettinger, Cynthia A Thomson, Qiuyin Cai, Jie Wu, William J Blot, Alan A Arslan, Anne Zeleniuch-Jacquotte, et al.

Journal article  |  2018  |  International Journal of Epidemiology

Genome-wide DNA methylation assessment of 'BRCA1-like' early-onset breast cancer: Data from the Australian Breast Cancer Family Registry

Cameron M Scott, Ee Ming Wong, JiHoon Eric Joo, Pierre-Antoine Dugue, Chol-Hee Jung, Neil O'Callaghan, James Dowty, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2018  |  Experimental and Molecular Pathology

Women's role in the rise in drinking in Australia 1950-80: an age-period-cohort analysis of data from the Melbourne Collaborative Cohort Study

Oliver Stanesby, Harindra Jayasekara, Sarah Callinan, Robin Room, Dallas English, Graham G Giles, Robert J MacInnis, Roger L Milne, Michael Livingston

Journal article  |  2018  |  Addiction

The association between low-density lipoprotein cholesterol predicted by HMGCR genetic variants and breast cancer risk may be mediated by body mass index

Siddhartha Kar, Hermann Brenner, Graham Giles, Dezheng Huo, Roger Milne, Gad Rennert, Jacques Simard, Wei Zheng, Stephen Burgess, Paul Pharoah

Journal article  |  2018

Orho-Melander et al. recently reported that lower low-density lipoprotein cholesterol (LDLC) as predicted by the T-allele of the v..

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

Siddhartha Kar, Irene Andrulis, Hermann Brenner, Stephen Burgess, Jenny Chang-Claude, Daniel Considine, Thilo Dörk, Gareth Evans, Manuela Gago-Domínguez, Graham Giles, Mikael Hartman, Dezheng Huo, Rudolf Kaaks, Jingmei Li, Artitaya Lophatananon, Sara Margolin, Roger Milne, Kenneth Muir, Håkan Olsson, Kevin Punie, et al.

Journal article  |  2018

Abstract Observational studies suggest that higher birth weight (BW) is associated with increased risk of breast cancer in adult l..

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

Marco Matejcic, Edward J Saunders, Tokhir Dadaev, Mark N Brook, Kan Wang, Xin Sheng, Ali Amin Al Olama, Fredrick R Schumacher, Sue A Ingles, Koveela Govindasami, Sara Benlloch, Sonja Berndt, Demetrius Albanes, Stella Koutros, Kenneth Muir, Victoria L Stevens, Susan M Gapstur, Catherine M Tangen, Jyotsna Batra, Judith Clements, et al.

Journal article  |  2018  |  Nature Communications

Domain-specific physical activity and the risk of colorectal cancer: results from the Melbourne Collaborative Cohort Study

Shahid Mahmood, Dallas R English, Robert J MacInnis, Amalia Karahalios, Neville Owen, Roger L Milne, Graham G Giles, Brigid M Lynch

Journal article  |  2018  |  BMC Cancer

Age-specific breast cancer risk by body mass index and familial risk: prospective family study cohort (ProF-SC)

John L Hopper, Gillian S Dite, Robert J MacInnis, Yuyan Liao, Nur Zeinomar, Julia A Knight, Melissa C Southey, Roger L Milne, Wendy K Chung, Graham G Giles, Jeanine M Genkinger, Sue-Anne McLachlan, Michael L Friedlander, Antonis C Antoniou, Prue C Weideman, Gord Glendon, Stephanie Nesci, Irene L Andrulis, Saundra S Buys, Mary B Daly, et al.

Journal article  |  2018  |  Breast Cancer Research

Differences in cancer survival by sex: a population-based study using cancer registry data

Nina Afshar, Dallas R English, Vicky Thursfield, Paul L Mitchell, Luc Te Marvelde, Helen Farrugia, Graham G Giles, Roger L Milne

Journal article  |  2018  |  Cancer Causes & Control

High dietary calcium intakes in men, not women, are associated with increased all-cause mortality: the Melbourne Collaborative Cohort Study

Alexander Rodriguez, David Scott, Belal Khan, Allison Hodge, Dallas English, Graham Giles, Bo Abrahamsen, Peter Ebeling

Conference Proceedings  |  2018  |  JOURNAL OF BONE AND MINERAL RESEARCH

Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women

Minouk J Schoemaker, Hazel B Nichols, Lauren B Wright, Mark N Brook, Michael E Jones, Katie M O'Brien, Hans-Olov Adami, Laura Baglietto, Leslie Bernstein, Kimberly A Bertrand, Marie-Christine Boutron-Ruault, Tonje Braaten, Yu Chen, Avonne E Connor, Miren Dorronsoro, Laure Dossus, A Heather Eliassen, Graham G Giles, Susan E Hankinson, Rudolf Kaaks, et al.

Journal article  |  2018  |  JAMA Oncology

Age at diagnosis and the surgical management of small renal carcinomas: findings from a cross-sectional population-based study

Victoria M White, David JT Marco, Damien Bolton, Nathan Papa, Rachel E Neale, Michael Coory, Ian D Davis, Simon Wood, Graham G Giles, Susan J Jordan

Journal article  |  2018  |  BJU International

Low Free Testosterone and Prostate Cancer Risk: A Collaborative Analysis of 20 Prospective Studies

Eleanor L Watts, Paul N Appleby, Aurora Perez-Cornago, H Bas Bueno-de-Mesquita, June M Chan, Chu Chen, Barbara A Cohn, Michael B Cook, Leon Flicker, Neal D Freedman, Graham G Giles, Edward Giovannucci, Randi E Gislefoss, Graeme J Hankey, Rudolf Kaaks, Paul Knekt, Laurence N Kolonel, Tatsuhiko Kubo, Loic Le Marchand, Robert N Luben, et al.

Journal article  |  2018  |  European Urology

Relationships between intensity, duration, cumulative dose, and timing of smoking with age at menopause: A pooled analysis of individual data from 17 observational studies

Dongshan Zhu, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Janet E Cade, Darren C Greenwood, Sybil L Crawford, Nancy E Avis, Ellen B Gold, Ellen S Mitchell, Nancy F Woods, Debra Anderson, Daniel E Brown, Lynnette L Sievert, Eric J Brunner, Diana Kuh, Rebecca Hardy, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, et al.

Journal article  |  2018  |  PLOS Medicine

Pooled Analysis of Nine Cohorts Reveals Breast Cancer Risk Factors by Tumor Molecular Subtype

Mia M Gaudet, Gretchen L Gierach, Brian D Carter, Juhua Luo, Roger L Milne, Elisabete Weiderpass, Graham G Giles, Rulla M Tamimi, A Heather Eliassen, Bernard Rosner, Alicja Wolk, Hans-Olov Adami, Karen L Margolis, Susan M Gapstur, Montserrat Garcia-Closas, Louise A Brinton

Journal article  |  2018  |  Cancer Research

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions.

Nicholas Mancuso, Simon Gayther, Alexander Gusev, Wei Zheng, Kathryn L Penney, Zsofia Kote-Jarai, Rosalind Eeles, Matthew Freedman, Christopher Haiman, Bogdan Pasaniuc, undefined PRACTICAL consortium

Journal article  |  2018  |  Nature Communications

Although genome-wide association studies (GWAS) for prostate cancer (PrCa) have identified more than 100 risk regions, most of the..

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

Fumiaki Imamura, Amanda Fretts, Matti Marklund, Andres V Ardisson Korat, Wei-Sin Yang, Maria Lankinen, Waqas Qureshi, Catherine Helmer, Tzu-An Chen, Kerry Wong, Julie K Bassett, Rachel Murphy, Nathan Tintle, Chaoyu Ian Yu, Ingeborg A Brouwer, Kuo-Liong Chien, Alexis C Frazier-Wood, Liana C del Gobbo, Luc Djousse, Johanna M Geleijnse, et al.

Journal article  |  2018  |  PLOS Medicine

High calcium intake in men not women is associated with all-cause mortality risk: Melbourne Collaborative Cohort Study

Alexander J Rodriguez, David Scott, Belal Khan, Allison Hodge, Dallas R English, Graham G Giles, B Abrahamsen, Peter R Ebeling

Journal article  |  2018  |  Archives of Osteoporosis

Heritable methylation marks associated with breast and prostate cancer risk

Pierre-Antoine Dugue, James G Dowty, Jihoon E Joo, Ee M Wong, Enes Makalic, Daniel F Schmidt, Dallas R English, John L Hopper, John Pedersen, Gianluca Severi, Robert J MacInnis, Roger L Milne, Graham G Giles, Melissa C Southey

Journal article  |  2018  |  The Prostate

Relationships between nitrogen dioxide exposure, post-bronchodilator airflow obstruction and gas transfer in middle-age

Jennifer Perret, Gayan Bowatte, Luke Knibbs, David Johns, Caroline Lodge, Adrian Lowe, Bui Dinh, Melanie Matheson, Bruce Thompson, Stephen Morrison, Graham Giles, E Haydn Walters, Michael Abramson, Shyamali Dharmage

Conference Proceedings  |  2018  |  Occupational and Environmental Health

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

Yingchang Lu, Alicia Beeghly-Fadiel, Lang Wu, Xingyi Guo, Bingshan Li, Joellen M Schildkraut, Hae Kyung Im, Yian A Chen, Jennifer B Permuth, Brett M Reid, Jamie K Teer, Kirsten B Moysich, Irene L Andrulis, Hoda Anton-Culver, Banu K Arun, Elisa V Bandera, Rosa B Barkardottir, Daniel R Barnes, Javier Benitez, Line Bjorge, et al.

Journal article  |  2018  |  Cancer Research

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Molly Went, Amit Sud, Asta Försti, Britt-Marie Halvarsson, Niels Weinhold, Scott Kimber, Mark van Duin, Gudmar Thorleifsson, Amy Holroyd, David C Johnson, Ni Li, Giulia Orlando, Philip J Law, Mina Ali, Bowang Chen, Jonathan S Mitchell, Daniel F Gudbjartsson, Rowan Kuiper, Owen W Stephens, Uta Bertsch, et al.

Journal article  |  2018  |  Nature Communications

Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of ..

Female reproductive history and risk of type 2 diabetes: A prospective analysis of 126 721 women

Nirmala Pandeya, Rachel R Huxley, Hsin-Fang Chung, Annette J Dobson, Diana Kuh, Rebecca Hardy, Janet E Cade, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Panayotes Demakakos, Mette Kildevaeld Simonsen, Hans-Olov Adami, Elisabete Weiderpass, Gita D Mishra

Journal article  |  2018  |  Diabetes, Obesity and Metabolism

Dietary intake of one-carbon metabolism nutrients and DNA methylation in peripheral blood

James A Chamberlain, Pierre-Antoine Dugue, Julie K Bassett, Allison M Hodge, Maree T Brinkman, JiHoon E Joo, Chol-Hee Jung, Enes Makalic, Daniel F Schmidt, John L Hopper, Daniel D Buchanan, Dallas R English, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2018  |  The American Journal of Clinical Nutrition

Childhood Respiratory Risk Factor Profiles and Middle-Age Lung Function: A Prospective Cohort Study from the First to Sixth Decade

Dinh S Bui, Haydn E Walters, John A Burgess, Jennifer L Perret, Minh Q Bui, Gayan Bowatte, Adrian J Lowe, Melissa A Russell, Bruce R Thompson, Garun S Hamilton, Alan L James, Graham G Giles, Paul S Thomas, Debbie Jarvis, Cecilie Svanes, Judith Garcia-Aymerich, Bircan Erbas, Peter A Frith, Katrina J Allen, Michael J Abramson, et al.

Journal article  |  2018  |  Annals of the American Thoracic Society

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

Linda E Kelemen, Madalene Earp, Brooke L Fridley, Georgia Chenevix-Trench, Peter A Fasching, Matthias W Beckmann, Arif B Ekici, Alexander Hein, Diether Lambrechts, Sandrina Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Mary Anne Rossing, Jennifer A Doherty, Jenny Chang-Claude, Sabine Behrens, Kirsten B Moysich, Rikki Cannioto, Shashikant Lele, Kunle Odunsi, et al.

Journal article  |  2018  |  International Journal of Molecular Sciences

Sunscreen Use and Melanoma Risk Among Young Australian Adults

Caroline G Watts, Martin Drummond, Chris Goumas, Helen Schmid, Bruce K Armstrong, Joanne F Aitken, Mark A Jenkins, Graham G Giles, John L Hopper, Graham J Mann, Anne E Cust

Journal article  |  2018  |  JAMA Dermatology

Identification of nine new susceptibility loci for endometrial cancer

Tracy A O'Mara, Dylan M Glubb, Frederic Amant, Daniela Annibali, Katie Ashton, John Attia, Paul L Auer, Matthias W Beckmann, Amanda Black, Manjeet K Bolla, Hiltrud Brauch, Hermann Brenner, Louise Brinton, Daniel D Buchanan, Barbara Burwinkel, Jenny Chang-Claude, Stephen J Chanock, Chu Chen, Maxine M Chen, Timothy HT Cheng, et al.

Journal article  |  2018  |  Nature Communications

Pancreatic cancer risk is modulated by inflammatory potential of diet and ABO genotype: a consortia-based evaluation and replication study

Samuel O Antwi, William R Bamlet, Katrina S Pedersen, Kari G Chaffee, Harvey A Risch, Nitin Shivappa, Susan E Steck, Kristin E Anderson, Paige M Bracci, Jerry Polesel, Diego Serraino, Carlo La Vecchia, Cristina Bosetti, Donghui Li, Ann L Oberg, Alan A Arslan, Demetrius Albanes, Eric J Duell, Inge Huybrechts, Laufey T Amundadottir, et al.

Journal article  |  2018  |  Carcinogenesis

Body mass index and age at natural menopause: an international pooled analysis of 11 prospective studies

Dongshan Zhu, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Diana Kuh, Sybil L Crawford, Ellen B Gold, Nancy E Avis, Graham G Giles, Fiona Bruinsma, Hans-Olov Adami, Elisabete Weiderpass, Darren C Greenwood, Janet E Cade, Ellen S Mitchell, Nancy F Woods, Eric J Brunner, Mette Kildevaeld Simonsen, Gita D Mishra

Journal article  |  2018  |  European Journal of Epidemiology

Family history-based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios

Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins, Driss Ait Ouakrim

Journal article  |  2018  |  PLOS Medicine

Childhood measles contributes to post-bronchodilator airflow obstruction in middle-aged adults: A cohort study

Jennifer L Perret, Melanie C Matheson, Lyle C Gurrin, David P Johns, John A Burgess, Bruce R Thompson, Adrian J Lowe, James Markos, Stephen S Morrison, Christine F McDonald, Richard Wood-Baker, Cecilie Svanes, Paul S Thomas, John L Hopper, Graham G Giles, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage

Journal article  |  2018  |  Respirology

Dietary intake of nutrients involved in one-carbon metabolism and risk of urothelial cell carcinoma: A prospective cohort study

Pierre-Antoine Dugue, Maree T Brinkman, Allison M Hodge, Julie K Bassett, Damien Bolton, Anthony Longano, John L Hopper, Melissa C Southey, Dallas R English, Roger L Milne, Graham G Giles

Journal article  |  2018  |  International Journal of Cancer

HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes

Sophia S Wang, Mary Carrington, Sonja I Berndt, Susan L Slager, Paige M Bracci, Jenna Voutsinas, James R Cerhan, Karin E Smedby, Henrik Hjalgrim, Joseph Vijai, Lindsay M Morton, Roel Vermeulen, Ora Paltiel, Claire M Vajdic, Martha S Linet, Alexandra Nieters, Silvia de Sanjose, Wendy Cozen, Elizabeth E Brown, Jennifer Turner, et al.

Journal article  |  2018  |  Cancer Research

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

Madalene Earp, Jonathan P Tyrer, Stacey J Winham, Hui-Yi Lin, Ganna Chornokur, Joe Dennis, Katja KH Aben, Hoda Anton-Culver, Natalia Antonenkova, Elisa V Bandera, Yukie T Bean, Matthias W Beckmann, Line Bjorge, Natalia Bogdanova, Louise A Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Clareann H Bunker, Ralf Butzow, Ian G Campbell, et al.

Journal article  |  2018  |  PLOS ONE

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

Lang Wu, Wei Shi, Jirong Long, Xingyi Guo, Kyriaki Michailidou, Jonathan Beesley, Manjeet K Bolla, Xiao-Ou Shu, Yingchang Lu, Qiuyin Cai, Fares Al-Ejeh, Esdy Rozali, Qin Wang, Joe Dennis, Bingshan Li, Chenjie Zeng, Helian Feng, Alexander Gusev, Richard T Barfield, Irene L Andrulis, et al.

Journal article  |  2018  |  Nature Genetics

Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life

Dinh S Bui, Caroline J Lodge, John A Burgess, Adrian J Lowe, Jennifer Perret, Minh Q Bui, Gayan Bowatte, Lyle Gurrin, David P Johns, Bruce R Thompson, Garun S Hamilton, Peter A Frith, Alan L James, Paul S Thomas, Deborah Jarvis, Cecilie Svanes, Melissa Russell, Stephen C Morrison, Iain Feather, Katrina J Allen, et al.

Journal article  |  2018  |  The Lancet Respiratory Medicine

Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980793 adults from 68 prospective studies

Louisa Gnatiuc, William G Herrington, Jim Halsey, Jaakko Tuomilehto, Xianghau Fang, Hyeon C Kim, Dirk DeBacquer, Annette J Dobson, Michael H Criqui, David R Jacobs, David A Leon, Sanne AE Peters, Hirotsugu Ueshima, Paul Sherliker, Richard Peto, Rory Collins, Rachel R Huxley, Jonathan R Emberson, Mark Woodward, Sarah Lewington, et al.

Journal article  |  2018  |  The Lancet Diabetes & Endocrinology

Female Reproductive and Hormonal Factors and Incidence of Primary Total Knee Arthroplasty Due to Osteoarthritis

Sultana Monira Hussain, Yuanyuan Wang, Graham G Giles, Stephen Graves, Anita Wluka, Flavia M Cicuttini

Conference Proceedings  |  2018  |  Arthritis & Rheumatology

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Fredrick R Schumacher, Ali Amin Al Olama, Sonja I Berndt, Sara Benlloch, Mahbubl Ahmed, Edward J Saunders, Tokhir Dadaev, Daniel Leongamornlert, Ezequiel Anokian, Clara Cieza-Borrella, Chee Goh, Mark N Brook, Xin Sheng, Laura Fachal, Joe Dennis, Jonathan Tyrer, Kenneth Muir, Artitaya Lophatananon, Victoria L Stevens, Susan M Gapstur, et al.

Journal article  |  2018  |  Nature Genetics

Resting heart rate, temporal changes in resting heart rate, and overall and cause-specific mortality

Mathias Seviiri, Brigid M Lynch, Allison M Hodge, Yi Yang, Danny Liew, Dallas R English, Graham G Giles, Roger L Milne, Pierre-Antoine Dugue

Journal article  |  2018  |  Heart

Impaired functional vitamin B6 status is associated with increased risk of lung cancer

Despoina Theofylaktopoulou, Oivind Midttun, Per M Ueland, Klaus Meyer, Anouar Fanidi, Wei Zheng, Xiao-Ou Shu, Yong-Bing Xiang, Ross Prentice, Mary Pettinger, Cynthia A Thomson, Graham G Giles, Allison Hodge, Qiuyin Cai, William J Blot, Jie Wu, Mikael Johansson, Johan Hultdin, Kjell Grankvist, Victoria L Stevens, et al.

Journal article  |  2018  |  International Journal of Cancer

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Tokhir Dadaev, Edward J Saunders, Paul J Newcombe, Ezequiel Anokian, Daniel A Leongamornlert, Mark N Brook, Clara Cieza-Borrella, Martina Mijuskovic, Sarah Wakerell, Ali Amin Al Olama, Fredrick R Schumacher, Sonja I Berndt, Sara Benlloch, Mahbubl Ahmed, Chee Goh, Xin Sheng, Zhuo Zhang, Kenneth Muir, Koveela Govindasami, Artitaya Lophatananon, et al.

Journal article  |  2018  |  Nature Communications

Informed consent and internet-based research in epidemiology

Laura Goddard, Fiona J Bruinsma, Graham G Giles

Journal article  |  2018  |  Medical Journal of Australia

Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors

Jihyoun Jeon, Mengmeng Du, Robert E Schoen, Michael Hoffmeister, Polly A Newcomb, Sonja I Berndt, Bette Caan, Peter T Campbell, Andrew T Chan, Jenny Chang-Claude, Graham G Giles, Jian Gong, Tabitha A Harrison, Jeroen R Huyghe, Eric J Jacobs, Li Li, Yi Lin, Loic Le Marchand, John D Potter, Conghui Qu, et al.

Journal article  |  2018  |  Gastroenterology

Predictors of new-onset chronic kidney disease in patients managed surgically for T1a renal cell carcinoma: An Australian population-based analysis

Thomas Ahn, Robert J Ellis, Victoria M White, Damien M Bolton, Michael D Coory, Ian D Davis, Ross S Francis, Graham G Giles, Glenda C Gobe, Carmel M Hawley, David W Johnson, David JT Marco, Megan McStea, Rachel E Neale, Elaine M Pascoe, Simon T Wood, Susan J Jordan

Journal article  |  2018  |  Journal of Surgical Oncology

Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases

LM FitzGerald, S Zhao, A Leonardson, MS Geybels, S Kolb, DW Lin, JL Wright, R Eeles, Z Kote-Jarai, K Govindasami, GG Giles, MC Southey, J Schleutker, TL Tammela, C Sipeky, KL Penney, MJ Stampfer, H Gronberg, F Wiklund, P Stattin, et al.

Journal article  |  2018  |  Prostate Cancer and Prostatic Diseases

Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

Sonja Neumeyer, Barbara L Banbury, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Stephanie A Bien, Dan D Buchanan, Katja Butterbach, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Stephen J Chanock, James Y Dai, Steven Gallinger, Edward L Giovannucci, Graham G Giles, William M Grady, Jochen Hampe, Michael Hoffmeister, et al.

Journal article  |  2018  |  British Journal of Cancer

Consumption of sugar-sweetened and artificially sweetened soft drinks and risk of obesity-related cancers

Allison M Hodge, Julie K Bassett, Roger L Milne, Dallas R English, Graham G Giles

Journal article  |  2018  |  Public Health Nutrition

Genome-wide average DNA methylation is determined in utero

Shuai Li, Ee Ming Wong, Pierre-Antoine Dugue, Allan F McRae, Eunae Kim, Ji-Hoon Eric Joo, Tuong L Nguyen, Jennifer Stone, Gillian S Dite, Nicola J Armstrong, Karen A Mather, Anbupalam Thalamuthu, Margaret J Wright, David Ames, Roger L Milne, Jeffrey M Craig, Richard Saffery, Grant W Montgomery, Yun-Mi Song, Joohon Sung, et al.

Journal article  |  2018  |  International Journal of Epidemiology

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.

Quinn T Ostrom, Ben Kinnersley, Margaret R Wrensch, Jeanette E Eckel-Passow, Georgina Armstrong, Terri Rice, Yanwen Chen, John K Wiencke, Lucie S McCoy, Helen M Hansen, Christopher I Amos, Jonine L Bernstein, Elizabeth B Claus, Dora Il'yasova, Christoffer Johansen, Daniel H Lachance, Rose K Lai, Ryan T Merrell, Sara H Olson, Siegal Sadetzki, et al.

Journal article  |  2018  |  Scientific Reports

Incidence of glioma is approximately 50% higher in males. Previous analyses have examined exposures related to sex hormones in wom..

Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses

Jodie N Painter, Tracy A O'Mara, Andrew P Morris, Timothy HT Cheng, Maggie Gorman, Lynn Martin, Shirley Hodson, Angela Jones, Nicholas G Martin, Scott Gordon, Anjali K Henders, John Attia, Mark McEvoy, Elizabeth G Holliday, Rodney J Scott, Penelope M Webb, Peter A Fasching, Matthias W Beckmann, Arif B Ekici, Alexander Hein, et al.

Journal article  |  2018  |  Cancer Medicine

Allostatic load and subsequent all-cause mortality: which biological markers drive the relationship? Findings from a UK birth cohort.

Raphaële Castagné, Valérie Garès, Maryam Karimi, Marc Chadeau-Hyam, Paolo Vineis, Cyrille Delpierre, Michelle Kelly-Irving, undefined Lifepath Consortium

Journal article  |  2018  |  European Journal of Epidemiology

The concept of allostatic load (AL) refers to the idea of a global physiological 'wear and tear' resulting from the adaptation to ..

Dietary inflammatory index or Mediterranean diet score as risk factors for total and cardiovascular mortality

AM Hodge, JK Bassett, P-A Dugue, N Shivappa, JR Hebert, RL Milne, DR English, GG Giles

Journal article  |  2018  |  Nutrition, Metabolism and Cardiovascular Diseases

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

Mara Colombo, Irene Lòpez-Perolio, Huong D Meeks, Laura Caleca, Michael T Parsons, Hongyan Li, Giovanna De Vecchi, Emma Tudini, Claudia Foglia, Patrizia Mondini, Siranoush Manoukian, Raquel Behar, Encarna B Gómez Garcia, Alfons Meindl, Marco Montagna, Dieter Niederacher, Ane Y Schmidt, Liliana Varesco, Barbara Wappenschmidt, Manjeet K Bolla, et al.

Journal article  |  2018  |  Human Mutation

Although the spliceogenic nature of the BRCA2 c.68-7T > A variant has been demonstrated, its association with cancer risk remains ..

DNA methylation-based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies

Pierre-Antoine Dugue, Julie K Bassett, JiHoon E Joo, Chol-Hee Jung, Ee Ming Wong, Margarita Moreno-Betancur, Daniel Schmidt, Enes Makalic, Shuai Li, Gianluca Severi, Allison M Hodge, Daniel D Buchanan, Dallas R English, John L Hopper, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2018  |  International Journal of Cancer

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

Maya Ghoussaini, Stacey L Edwards, Kyriaki Michailidou, Silje Nord, Richard Cowper-Sal Lari, Kinjal Desai, Siddhartha Kar, Kristine M Hillman, Susanne Kaufmann, Dylan M Glubb, Jonathan Beesley, Joe Dennis, Manjeet K Bolla, Qin Wang, Ed Dicks, Qi Guo, Marjanka K Schmidt, Mitul Shah, Robert Luben, Judith Brown, et al.

Journal article  |  2018  |  Nature Communications

This corrects the article DOI: 10.1038/ncomms5999.

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.

Jayaram Vijayakrishnan, James Studd, Peter Broderick, Ben Kinnersley, Amy Holroyd, Philip J Law, Rajiv Kumar, James M Allan, Christine J Harrison, Anthony V Moorman, Ajay Vora, Eve Roman, Sivaramakrishna Rachakonda, Sally E Kinsey, Eamonn Sheridan, Pamela D Thompson, Julie A Irving, Rolf Koehler, Per Hoffmann, Markus M Nöthen, et al.

Journal article  |  2018  |  Nature Communications

Genome-wide association studies (GWAS) have advanced our understanding of susceptibility to B-cell precursor acute lymphoblastic l..

Obtaining high quality transcriptome data from formalin-fixed, paraffin-embedded diagnostic prostate tumor specimens

Liesel M FitzGerald, Chol-hee Jung, Ee Ming Wong, JiHoon E Joo, Jodee A Gould, Vivien Vasic, Julie K Bassett, Neil O'Callaghan, Tim Nottle, John Pedersen, Graham G Giles, Melissa C Southey

Journal article  |  2018  |  Laboratory Investigation

Traffic related air pollution and development and persistence of asthma and low lung function

Gayan Bowatte, Caroline J Lodge, Luke D Knibbs, Bircan Erbas, Jennifer L Perret, Bin Jalaludin, Geoffrey G Morgan, Dinh S Bui, Graham G Giles, Garun S Hamilton, Richard Wood-Baker, Paul Thomas, Bruce R Thompson, Melanie C Matheson, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage

Journal article  |  2018  |  Environment International

Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium

Anja Rudolph, Minsun Song, Mark N Brook, Roger L Milne, Nasim Mavaddat, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Amber N Wilcox, John L Hopper, Melissa C Southey, Renske Keeman, Peter A Fasching, Matthias W Beckmann, Manuela Gago-Dominguez, Jose E Castelao, Pascal Guenel, Therese Truong, Stig E Bojesen, et al.

Journal article  |  2018  |  International Journal of Epidemiology

Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

Suzanne C Dixon-Suen, Christina M Nagle, Aaron P Thrift, Paul DP Pharoah, Ailith Ewing, Celeste Leigh Pearce, Wei Zheng, Georgia Chenevix-Trench, Peter A Fasching, Matthias W Beckmann, Diether Lambrechts, Ignace Vergote, Sandrina Lambrechts, Els Van Nieuwenhuysen, Mary Anne Rossing, Jennifer A Doherty, Kristine G Wicklund, Jenny Chang-Claude, Audrey Y Jung, Kirsten B Moysich, et al.

Journal article  |  2018  |  British Journal of Cancer

Novel associations between blood DNA methylation and body mass index in middle-aged and older adults

YM Geurts, P-A Dugue, JE Joo, E Makalic, C-H Jung, W Guan, S Nguyen, ML Grove, EM Wong, AM Hodge, JK Bassett, LM FitzGerald, H Tsimiklis, L Baglietto, G Severi, DF Schmidt, DD Buchanan, RJ MacInnis, JL Hopper, JS Pankow, et al.

Journal article  |  2018  |  International Journal of Obesity

Socioeconomic status, non-communicable disease risk factors, and walking speed in older adults: multi-cohort population based study

Silvia Stringhini, Cristian Carmeli, Markus Jokela, Mauricio Avendano, Cathal McCrory, Angelo d'Errico, Murielle Bochud, Henrique Barros, Giuseppe Costa, Marc Chadeau-Hyam, Cyrille Delpierre, Martina Gandini, Silvia Fraga, Marcel Goldberg, Graham G Giles, Camille Lassale, Rose Anne Kenny, Michelle Kelly-Irving, Fred Paccaud, Richard Layte, et al.

Journal article  |  2018  |  BMJ

A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium

Myrto Barrdahl, Federico Canzian, Mia M Gaudet, Susan M Gapstur, Antonia Trichopoulou, Kostas Tsilidis, Carla H van Gils, Signe Borgquist, Elisabete Weiderpass, Kay-Tee Khaw, Graham G Giles, Roger L Milne, Loic Le Marchand, Christopher Haiman, Sara Lindstrom, Peter Kraft, David J Hunter, Regina Ziegler, Stephen J Chanock, Xiaohong R Yang, et al.

Journal article  |  2018  |  International Journal of Cancer

Lifetime alcohol intake and risk of non-Hodgkin lymphoma: Findings from the Melbourne Collaborative Cohort Study

Harindra Jayasekara, Surender Juneja, Allison M Hodge, Robin Room, Roger L Milne, John L Hopper, Dallas R English, Graham G Giles, Robert J MacInnis

Journal article  |  2018  |  International Journal of Cancer

Family History of Cancer and Risk of Biliary Tract Cancers: Results from the Biliary Tract Cancers Pooling Project

Alison L Van Dyke, Margaret S Langhamer, Bin Zhu, Ruth M Pfeiffer, Demetrius Albanes, Gabriella Andreotti, Laura E Beane Freeman, Andrew T Chan, Neal D Freedman, Susan M Gapstur, Graham G Giles, Francine Grodstein, Linda M Liao, Juhua Luo, Roger L Milne, Kristine R Monroe, Marian L Neuhouser, Jenny N Poynter, Mark P Purdue, Kim Robien, et al.

Journal article  |  2018  |  Cancer Epidemiology Biomarkers & Prevention

Association of DNA Methylation-Based Biological Age With Health Risk Factors and Overall and Cause-Specific Mortality

Pierre-Antoine Dugue, Julie K Bassett, JiHoon E Joo, Laura Baglietto, Chol-Hee Jung, Ee Ming Wong, Giovanni Fiorito, Daniel Schmidt, Enes Makalic, Shuai Li, Margarita Moreno-Betancur, Daniel D Buchanan, Paolo Vineis, Dallas R English, John L Hopper, Gianluca Severi, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2018  |  American Journal of Epidemiology

Heritable DNA methylation marks associated with susceptibility to breast cancer

Jihoon E Joo, James G Dowty, Roger L Milne, Ee Ming Wong, Pierre-Antoine Dugue, Dallas English, John L Hopper, David E Goldgar, Graham G Giles, Melissa C Southey

Journal article  |  2018  |  Nature Communications

Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study

Shuai Li, Ee Ming Wong, Minh Bui, Tuong L Nguyen, Ji-Hoon Eric Joo, Jennifer Stone, Gillian S Dite, Graham G Giles, Richard Saffery, Melissa C Southey, John L Hopper

Journal article  |  2018  |  Clinical Epigenetics

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Alison P Klein, Brian M Wolpin, Harvey A Risch, Rachael Z Stolzenberg-Solomon, Evelina Mocci, Mingfeng Zhang, Federico Canzian, Erica J Childs, Jason W Hoskins, Ashley Jermusyk, Jun Zhong, Fei Chen, Demetrius Albanes, Gabriella Andreotti, Alan A Arslan, Ana Babic, William R Bamlet, Laura Beane-Freeman, Sonja I Berndt, Amanda Blackford, et al.

Journal article  |  2018  |  Nature Communications

Is RNASEL:p.Glu265*a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

Tu Nguyen-Dumont, Zhi L Teo, Fleur Hammet, Alexis Roberge, Maryam Mahmoodi, Helen Tsimiklis, Daniel J Park, Bernard J Pope, Andrew Lonie, Miroslav K Kapuscinski, Khalid Mahmood, David E Goldgar, Graham G Giles, Ingrid Winship, John L Hopper, Melissa C Southey

Journal article  |  2018  |  BMC Cancer

Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype

Harindra Jayasekara, Dallas R English, Andrew Haydon, Allison M Hodge, Brigid M Lynch, Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Melissa C Southey, Mark A Jenkins, Robin Room, John L Hopper, Roger L Milne, Daniel D Buchanan, Graham G Giles, Robert J MacInnis

Journal article  |  2018  |  International Journal of Cancer

Epigenetic supersimilarity of monozygotic twin pairs

Timothy E Van Baak, Cristian Coarfa, Pierre-Antoine Dugue, Giovanni Fiorito, Eleonora Laritsky, Maria S Baker, Noah J Kessler, Jianrong Dong, Jack D Duryea, Matt J Silver, Ayden Saffari, Andrew M Prentice, Sophie E Moore, Akram Ghantous, Michael N Routledge, Yun Yun Gong, Zdenko Herceg, Paolo Vineis, Gianluca Severi, John L Hopper, et al.

Journal article  |  2018  |  Genome Biology

The utility of DNA extracted from saliva for genome-wide molecular research platforms.

Fiona J Bruinsma, Jihoon E Joo, Ee Ming Wong, Graham G Giles, Melissa C Southey

Journal article  |  2018  |  BMC Research Notes

OBJECTIVE: The study aimed to investigate the suitability of DNA extracted from saliva for high throughput molecular genotyping an..

Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas

Mark Clendenning, Alvin Huang, Harindra Jayasekara, Marie Lorans, Susan Preston, Neil O'Callaghan, Bernard J Pope, Finlay A Macrae, Ingrid M Winship, Roger L Milne, Graham G Giles, Dallas R English, John L Hopper, Aung K Win, Mark A Jenkins, Melissa C Southey, Christophe Rosty, Daniel D Buchanan

Journal article  |  2018  |  Familial Cancer

Prediagnostic body size and risk of amyotrophic lateral sclerosis death in 10 studies

Eilis J O'Reilly, Molin Wang, Hans-Olov Adami, Alvaro Alonso, Leslie Bernstein, Piet van den Brandt, Julie Buring, Sarah Daugherty, Dennis Deapen, D Michal Freedman, Dallas R English, Graham G Giles, Niclas Hakansson, Tobias Kurth, Catherine Schairer, Elisabete Weiderpass, Alicja Wolk, Stephanie A Smith-Warner

Journal article  |  2018  |  Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Early-onset baldness and the risk of aggressive prostate cancer: findings from a case-control study

Nathan P Papa, Robert J MacInnis, Dallas R English, Damien Bolton, Ian D Davis, Nathan Lawrentschuk, Jeremy L Millar, Gianluca Severi, John L Hopper, Graham G Giles

Journal article  |  2018  |  Cancer Causes & Control

Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men

Eleanor L Watts, Paul N Appleby, Demetrius Albanese, Amanda Black, June M Chan, Chu Chen, Piera M Cirillo, Barbara A Cohn, Michael B Cook, Jenny L Donovan, Luigi Ferrucci, Cedric F Garland, Graham G Giles, Phyllis J Goodman, Laurel A Habel, Christopher A Haiman, Jeff MP Holly, Robert N Hoover, Rudolf Kaaks, Paul Knekt, et al.

Journal article  |  2017  |  PLOS ONE

Mammographic density and risk of breast cancer by tumor characteristics: a case-control study

Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Catriona McLean, Melissa C Southey, Dallas R English, Graham G Giles, John L Hopper

Journal article  |  2017  |  BMC Cancer

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Roger L Milne, Karoline B Kuchenbaecker, Kyriaki Michailidou, Jonathan Beesley, Siddhartha Kar, Sara Lindstrom, Shirley Hui, Audrey Lemacon, Penny Soucy, Joe Dennis, Xia Jiang, Asha Rostamianfar, Hilary Finucane, Manjeet K Bolla, Lesley McGuffog, Qin Wang, Cora M Aalfs, Marcia Adams, Julian Adlard, Simona Agata, et al.

Journal article  |  2017  |  Nature Genetics

Dietary protein from different food sources, incident metabolic syndrome and changes in its components: An 11-year longitudinal study in healthy community-dwelling adults

Xianwen Shang, David Scott, Allison Hodge, Dallas R English, Graham G Giles, Peter R Ebeling, Kerrie M Sanders

Journal article  |  2017  |  Clinical Nutrition

Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies

Jason HY Wu, Matti Marklund, Fumiaki Imamura, Nathan Tintle, Andres V Ardisson Korat, Janette de Goede, Xia Zhou, Wei-Sin Yang, Marcia C de Oliveira Otto, Janine Kroger, Waqas Qureshi, Jyrki K Virtanen, Julie K Bassett, Alexis C Frazier-Wood, Maria Lankinen, Rachel A Murphy, Kalina Rajaobelina, Liana C Del Gobbo, Nita G Forouhi, Robert Luben, et al.

Journal article  |  2017  |  The Lancet Diabetes & Endocrinology

An epigenome-wide association study meta-analysis of educational attainment

R Karlsson Linner, RE Marioni, CA Rietveld, AJ Simpkin, NM Davies, K Watanabe, NJ Armstrong, K Auro, C Baumbach, MJ Bonder, J Buchwald, G Fiorito, K Ismail, S Iurato, A Joensuu, P Karell, S Kasela, J Lahti, AF Mcrae, PR Mandaviya, et al.

Journal article  |  2017  |  Molecular Psychiatry

Association between Cigar or Pipe Smoking and Cancer Risk in Men: A Pooled Analysis of Five Cohort Studies

Jyoti Malhotra, Claire Borron, Neal D Freedman, Christian C Abnet, Piet A van den Brandt, Emily White, Roger L Milne, Graham G Giles, Paolo Boffetta

Journal article  |  2017  |  Cancer Prevention Research

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.

Amit Sud, Hauke Thomsen, Philip J Law, Asta Försti, Miguel Inacio da Silva Filho, Amy Holroyd, Peter Broderick, Giulia Orlando, Oleg Lenive, Lauren Wright, Rosie Cooke, Douglas Easton, Paul Pharoah, Alison Dunning, Julian Peto, Federico Canzian, Rosalind Eeles, ZSofia Kote-Jarai, Kenneth Muir, Nora Pashayan, et al.

Journal article  |  2017  |  Nature Communications

Several susceptibility loci for classical Hodgkin lymphoma have been reported. However, much of the heritable risk is unknown. Her..

Cohort Profile: The Melbourne Collaborative Cohort Study (Health 2020)

RL Milne, AS Fletcher, RJ MacInnis, AM Hodge, AH Hopkins, JK Bassett, FJ Bruinsma, BM Lynch, PA Dugue, H Jayasekara, MT Brinkman, LV Popowski, L Baglietto, G Severi, K O'Dea, JL Hopper, MC Southey, DR English, GG Giles

Journal article  |  2017  |  International Journal of Epidemiology

Body mass index and breast cancer survival: a Mendelian randomization analysis

Qi Guo, Stephen Burgess, Constance Turman, Manjeet K Bolla, Qin Wang, Michael Lush, Jean Abraham, Kristiina Aittomaki, Irene L Andrulis, Carmel Apicella, Volker Arndt, Myrto Barrdahl, Javier Benitez, Christine D Berg, Carl Blomqvist, Stig E Bojesen, Bernardo Bonanni, Judith S Brand, Hermann Brenner, Annegien Broeks, et al.

Journal article  |  2017  |  International Journal of Epidemiology

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1

Xiang Jiao, Christos Aravidis, Rajeshwari Marikkannu, Johanna Rantala, Simone Picelli, Tatjana Adamovic, Tao Liu, Paula Maguire, Barbara Kremeyer, Liping Luo, Susanna Von Holst, Vinaykumar Kontham, Jessada Thutkawkorapin, Sara Margolin, Quan Du, Johanna Lundin, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, et al.

Journal article  |  2017  |  Oncotarget

Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation

Giovanni Fiorito, Silvia Polidoro, Pierre-Antoine Dugue, Mika Kivimaki, Erica Ponzi, Giuseppe Matullo, Simonetta Guarrera, Manuela B Assumma, Panagiotis Georgiadis, Soterios A Kyrtopoulos, Vittorio Krogh, Domenico Palli, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Marc Chadeau-Hyam, Silvia Stringhini, Gianluca Severi, Allison M Hodge, Graham G Giles, et al.

Journal article  |  2017  |  Scientific Reports

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study

Olivier Brouckaert, Anja Rudolph, Annouschka Laenen, Renske Keeman, Manjeet K Bolla, Qin Wang, Adelheid Soubry, Hans Wildiers, Irene L Andrulis, Volker Arndt, Matthias W Beckmann, Javier Benitez, Carl Blomqvist, Stig E Bojesen, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Georgia Chenevix-Trench, Ji-Yeob Choi, Sten Cornelissen, et al.

Journal article  |  2017  |  Breast Cancer Research

Association analysis identifies 65 new breast cancer risk loci

Kyriaki Michailidou, Sara Lindstrom, Joe Dennis, Jonathan Beesley, Shirley Hui, Siddhartha Kar, Audrey Lemacon, Penny Soucy, Dylan Glubb, Asha Rostamianfar, Manjeet K Bolla, Qin Wang, Jonathan Tyrer, Ed Dicks, Andrew Lee, Zhaoming Wang, Jamie Allen, Renske Keeman, Ursula Eilber, Juliet D French, et al.

Journal article  |  2017  |  Nature

The influence of unmet supportive care needs on anxiety and depression during cancer treatment and beyond: a longitudinal study of survivors of haematological cancers

Devesh Oberoi, Victoria M White, John F Seymour, H Miles Prince, Simon Harrison, Michael Jefford, Ingrid Winship, David Hill, Damien Bolton, Anne Kay, Jeremy Millar, Nicole Wong Doo, Graham Giles

Journal article  |  2017  |  Supportive Care in Cancer

Trends in the surgical management of stage 1 renal cell carcinoma: findings from a population-based study

Victoria White, David JT Marco, Damien Bolton, Ian Douglas Davis, Michael Jefford, David Hill, Henry Miles Prince, Jeremy L Millar, Ingrid M Winship, Michael Coory, Graham G Giles

Journal article  |  2017  |  BJU International

Distress and unmet needs during treatment and quality of life in early cancer survivorship: A longitudinal study of haematological cancer patients

Devesh V Oberoi, Victoria M White, John F Seymour, H Miles Prince, Simon Harrison, Michael Jefford, Ingrid Winship, David J Hill, Damien Bolton, Jeremy Millar, Nicole Wong Doo, Anne Kay, Graham Giles

Journal article  |  2017  |  European Journal of Haematology

Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium

Myrto Barrdahl, Anja Rudolph, John L Hopper, Melissa C Southey, Annegien Broeks, Peter A Fasching, Matthias W Beckmann, Manuela Gago-Dominguez, J Esteban Castelao, Pascal Guenel, Therese Truong, Stig E Bojesen, Susan M Gapstur, Mia M Gaudet, Hermann Brenner, Volker Arndt, Hiltrud Brauch, Ute Hamann, Arto Mannermaa, Diether Lambrechts, et al.

Journal article  |  2017  |  International Journal of Cancer

Occupational exposure to pesticides are associated with fixed airflow obstruction in middle-age

Sheikh M Alif, Shyamali C Dharmage, Geza Benke, Martine Dennekamp, John A Burgess, Jennifer L Perret, Caroline J Lodge, Stephen Morrison, David Peter Johns, Graham G Giles, Lyle C Gurrin, Paul S Thomas, John Llewelyn Hopper, Richard Wood-Baker, Bruce R Thompson, Iain H Feather, Roel Vermeulen, Hans Kromhout, E Haydn Walters, Michael J Abramson, et al.

Journal article  |  2017  |  Thorax

Circulating resistin levels and risk of multiple myeloma in three prospective cohorts

Loredana Santo, Lauren R Teras, Graham G Giles, Stephanie J Weinstein, Demetrius Albanes, Ye Wang, Ruth M Pfeiffer, Qing Lan, Nathaniel Rothman, Brenda M Birmann, Graham A Colditz, Michael N Pollak, Mark P Purdue, Jonathan N Hofmann

Journal article  |  2017  |  British Journal of Cancer

Traffic-related air pollution exposure over a 5-year period is associated with increased risk of asthma and poor lung function in middle age

Gayan Bowatte, Bircan Erbas, Caroline J Lodge, Luke D Knibbs, Lyle C Gurrin, Guy B Marks, Paul S Thomas, David P Johns, Graham G Giles, Jennie Hui, Martine Dennekamp, Jennifer L Perret, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage

Journal article  |  2017  |  European Respiratory Journal

Total and beverage-specific alcohol intake and the risk of aggressive prostate cancer: a case-control study

NP Papa, RJ MacInnis, H Jayasekara, DR English, D Bolton, ID Davis, N Lawrentschuk, JL Millar, J Pedersen, G Severi, MC Southey, JL Hopper, GG Giles

Journal article  |  2017  |  Prostate Cancer and Prostatic Diseases

Bronchial hyperresponsiveness and obesity in middle age: insights from an Australian cohort

John A Burgess, Melanie C Matheson, Fei Diao, David P Johns, Bircan Erbas, Adrian J Lowe, Lyle C Gurrin, Caroline J Lodge, Paul S Thomas, Stephen Morrison, Bruce R Thompson, Iain Feather, Jennifer L Perret, Michael J Abramson, Graham G Giles, John L Hopper, Shyamali C Dharmage, Eugene H Walters

Journal article  |  2017  |  European Respiratory Journal

The Premenopausal Breast Cancer Collaboration: A Pooling Project of Studies Participating in the National Cancer Institute Cohort Consortium

Hazel B Nichols, Minouk J Schoemaker, Lauren B Wright, Craig McGowan, Mark N Brook, Kathleen M McClain, Michael E Jones, Hans-Olov Adami, Claudia Agnoli, Laura Baglietto, Leslie Bernstein, Kimberly A Bertrand, William J Blots, Marie-Christine Boutron-Ruault, Lesley Butler, Yu Chenl, Michele M Doody, Laure Dossus, A Heather Eliassen, Graham G Giles, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

Continuing Medical Education: Age-related macular degeneration and mortality: the Melbourne Collaborative Cohort Study

MB McGuinness, RP Finger, A Karahalios, RH Guymer, DR English, EW Chong, AM Hodge, LD Robman, GG Giles, JA Simpson

Journal article  |  2017  |  Eye

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

Artitaya Lophatananon, Sarah Stewart-Brown, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch Garcia, David E Neal, Freddie C Hamdy, Jenny L Donovan, Graham G Giles, Liesel M Fitzgerald, Melissa C Southey, Paul Pharoah, Nora Pashayan, Henrik Gronberg, Fredrik Wiklund, Markus Aly, Janet L Stanford, Hermann Brenner, Aida K Dieffenbach, Volker Arndt, et al.

Journal article  |  2017  |  British Journal of Cancer

Twin birth changes DNA methylation of subsequent siblings

Shuai Li, Eunae Kim, Ee Ming Wong, Ji-Hoon Eric Joo, Tuong L Nguyen, Jennifer Stone, Yun-Mi Song, Louisa B Flander, Richard Saffery, Graham G Giles, Melissa C Southey, Joohon Sung, John L Hopper

Journal article  |  2017  |  Scientific Reports

Ejaculatory frequency and the risk of aggressive prostate cancer: Findings from a case-control study

Nathan P Papa, Robert J MacInnis, Dallas R English, Damien Bolton, Ian D Davis, Nathan Lawrentschuk, Jeremy L Millar, John Pedersen, Gianluca Severi, Melissa C Southey, John L Hopper, Graham G Giles

Journal article  |  2017  |  Urologic Oncology: Seminars and Original Investigations

Antihypertensive medication use and breast cancer risk Reply

Yi Yang, Brigid M Lynch, Allison M Hodge, Danny Liew, Catriona A Mclean, Mathias Seviiri, Melissa C Southey, John L Hopper, Dallas R English, Graham G Giles, Roger L Milne, Pierre-Antoine Dugue

Journal article  |  2017  |  Journal of Hypertension

A Pooled Analysis of 15 Prospective Cohort Studies on the Association between Fruit, Vegetable, and Mature Bean Consumption and Risk of Prostate Cancer

Joshua Petimar, Kathryn M Wilson, Kana Wu, Molin Wang, Demetrius Albanes, Piet A van den Brandt, Michael B Cook, Graham G Giles, Edward L Giovannucci, Gary E Goodman, Phyllis J Goodman, Niclas Hakansson, Kathy Helzlsouer, Timothy J Key, Laurence N Kolonel, Linda M Liao, Satu Mannisto, Marjorie L McCullough, Roger L Milne, Marian L Neuhouser, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

Association between Dairy Product Consumption and Incidence of Total Hip Arthroplasty for Osteoarthritis

Sultana Monira Hussain, Flavia M Cicuttini, Graham G Giles, Stephen E Graves, Anita Wluka, Yuanyuan Wang

Journal article  |  2017  |  The Journal of Rheumatology

Childhood Lung Function Predicts Adult Chronic Obstructive Pulmonary Disease and Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome

Dinh S Bui, John A Burgess, Adrian J Lowe, Jennifer L Perret, Caroline J Lodge, Bui Minh, Stephen Morrison, Bruce R Thompson, Paul S Thomas, Graham G Giles, Judith Garcia-Aymerich, Debbie Jarvis, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage

Journal article  |  2017  |  American Journal of Respiratory and Critical Care Medicine

25-Hydroxyvitamin D concentration and all-cause mortality: the Melbourne Collaborative Cohort Study

Alicia K Heath, Elizabeth J Williamson, David Kvaskoff, Allison M Hodge, Peter R Ebeling, Laura Baglietto, Rachel E Neale, Graham G Giles, Darryl W Eyles, Dallas R English

Journal article  |  2017  |  Public Health Nutrition

Associations between hip bone mineral density, aortic calcification and cardiac workload in community-dwelling older Australians

AJ Rodriguez, D Scott, A Hodge, DR English, GG Giles, PR Ebeling

Journal article  |  2017  |  Osteoporosis International

Blood pressure and risk of breast cancer, overall and by subtypes: a prospective cohort study

Yi Yang, Brigid M Lynch, Allison M Hodge, Danny Liew, Catriona A Mclean, Mathias Seviiri, Melissa C Southey, John L Hopper, Dallas R English, Graham G Giles, Roger L Milne, Pierre-Antoine Dugue

Journal article  |  2017  |  Journal of Hypertension

Young Adult and Usual Adult Body Mass Index and Multiple Myeloma Risk: A Pooled Analysis in the International Multiple Myeloma Consortium (IMMC)

Brenda M Birmann, Gabriella Andreotti, Anneclaire J De Roos, Nicola J Camp, Brian CH Chiu, John J Spinelli, Nikolaus Becker, Veronique Benhaim-Luzon, Parveen Bhatti, Paolo Boffetta, Paul Brennan, Elizabeth E Brown, Pierluigi Cocco, Laura Costas, Wendy Cozen, Silvia de Sanjose, Lenka Foretova, Graham G Giles, Marc Maynadie, Kirsten Moysich, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide

Anya Burton, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martin Lajous, Ruy Lopez-Ridaura, Megan Rice, Ana Pereira, Maria Luisa Garmendia, Rulla M Tamimi, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Samera A Qureshi, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, et al.

Journal article  |  2017  |  PLOS Medicine

Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations

Oivind Midttun, Despoina Theofylaktopoulou, Adrian McCann, Anouar Fanidi, David C Muller, Klaus Meyer, Arve Ulvik, Wei Zheng, Xiao-Ou Shu, Yong-Bing Xiang, Ross Prentice, Cynthia A Thomson, Mary Pettinger, Graham G Giles, Allison Hodge, Qiuyin Cai, William J Blot, Jie Wu, Mikael Johansson, Johan Hultdin, et al.

Journal article  |  2017  |  The American Journal of Clinical Nutrition

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer

Hermela Shimelis, Romy LS Mesman, Catharina Von Nicolai, Asa Ehlen, Lucia Guidugli, Charlotte Martin, Fabienne MGR Calleja, Huong Meeks, Emily Hallberg, Jamie Hinton, Jenna Lilyquist, Chunling Hu, Cora M Aalfs, Kristiina Aittomaki, Irene Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Javier Benitez, Natalia V Bogdanova, et al.

Journal article  |  2017  |  Cancer Research

Pooled analysis of active cigarette smoking and invasive breast cancer risk in 14 cohort studies

Mia M Gaudet, Brian D Carter, Louise A Brinton, Roni T Falk, Inger T Gram, Juhua Luo, Roger L Milne, Sarah J Nyante, Elisabete Weiderpass, Laura E Beane Freeman, Dale P Sandler, Kim Robien, Kristin E Anderson, Graham G Giles, Wendy Y Chen, Diane Feskanich, Tonje Braaten, Claudine Isaacs, Lesley M Butler, Woon-Puay Koh, et al.

Journal article  |  2017  |  International Journal of Epidemiology

The burden of cancer attributable to modifiable risk factors: the Australian cancer-PAF cohort consortium

Maria E Arriaga, Claire M Vajdic, Karen Canfell, Robert MacInnis, Peter Hull, Dianna J Magliano, Emily Banks, Graham G Giles, Robert G Cumming, Julie E Byles, Anne W Taylor, Jonathan E Shaw, Kay Price, Vasant Hirani, Paul Mitchell, Barbara-Ann Adelstein, Maarit A Laaksonen

Journal article  |  2017  |  BMJ Open

The course of anxiety, depression and unmet needs in survivors of diffuse large B cell lymphoma and multiple myeloma in the early survivorship period

Devesh Oberoi, Victoria White, John Seymour, H Miles Prince, Simon Harrison, Michael Jefford, Ingrid Winship, David Hill, Damien Bolton, Anne Kay, Jeremy Millar, Nicole Wong Doo, Graham Giles

Journal article  |  2017  |  Journal of Cancer Survivorship

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Felix R Day, Deborah J Thompson, Hannes Helgason, Daniel I Chasman, Hilary Finucane, Patrick Sulem, Katherine S Ruth, Sean Whalen, Abhishek K Sarkar, Eva Albrecht, Elisabeth Altmaier, Marzyeh Amini, Caterina M Barbieri, Thibaud Boutin, Archie Campbell, Ellen Demerath, Ayush Giri, Chunyan He, Jouke J Hottenga, Robert Karlsson, et al.

Journal article  |  2017  |  Nature Genetics

Socioeconomic indicators in epidemiologic research: A practical example from the LIFEPATH study

Angelo d'Errico, Fulvio Ricceri, Silvia Stringhini, Cristian Carmeli, Mika Kivimaki, Mel Bartley, Cathal McCrory, Murielle Bochud, Peter Vollenweider, Rosario Tumino, Marcel Goldberg, Marie Zins, Henrique Barros, Graham Giles, Gianluca Severi, Giuseppe Costa, Paolo Vineis

Journal article  |  2017  |  PLOS ONE

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.

Beatrice S Melin, Jill S Barnholtz-Sloan, Margaret R Wrensch, Christoffer Johansen, Dora Il'yasova, Ben Kinnersley, Quinn T Ostrom, Karim Labreche, Yanwen Chen, Georgina Armstrong, Yanhong Liu, Jeanette E Eckel-Passow, Paul A Decker, Marianne Labussière, Ahmed Idbaih, Khe Hoang-Xuan, Anna-Luisa Di Stefano, Karima Mokhtari, Jean-Yves Delattre, Peter Broderick, et al.

Journal article  |  2017  |  Nature Genetics

Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, but individual studies have ha..

gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels

Nicholas B Larson, Shannon McDonnell, Lisa Cannon Albright, Craig Teerlink, Janet Stanford, Elaine A Ostrander, William B Isaacs, Jianfeng Xu, Kathleen A Cooney, Ethan Lange, Johanna Schleutker, John D Carpten, Isaac Powell, Joan E Bailey-Wilson, Olivier Cussenot, Geraldine Cancel-Tassin, Graham G Giles, Robert J MacInnis, Christiane Maier, Alice S Whittemore, et al.

Journal article  |  2017  |  Genetic Epidemiology

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

Taru A Muranen, Dario Greco, Carl Blomqvist, Kristiina Aittomaki, Sofia Khan, Frans Hogervorst, Senno Verhoef, Paul DP Pharoah, Alison M Dunning, Mitul Shah, Robert Luben, Stig E Bojesen, Borge G Nordestgaard, Minouk Schoemaker, Anthony Swerdlow, Montserrat Garcia-Closas, Jonine Figueroa, Thilo Doerk, Natalia V Bogdanova, Per Hall, et al.

Journal article  |  2017  |  Genetics in Medicine

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Catherine M Phelan, Karoline B Kuchenbaecker, Jonathan P Tyrer, Siddhartha P Kar, Kate Lawrenson, Stacey J Winham, Joe Dennis, Ailith Pirie, Marjorie J Riggan, Ganna Chornokur, Madalene A Earp, Paulo C Lyra, Janet M Lee, Simon Coetzee, Jonathan Beesley, Lesley McGuffog, Penny Soucy, Ed Dicks, Andrew Lee, Daniel Barrowdale, et al.

Journal article  |  2017  |  Nature Genetics

Worldwide comparison of survival from childhood leukaemia for 1995-2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries.

Audrey Bonaventure, Rhea Harewood, Charles A Stiller, Gemma Gatta, Jacqueline Clavel, Daniela C Stefan, Helena Carreira, Devon Spika, Rafael Marcos-Gragera, Rafael Peris-Bonet, Marion Piñeros, Milena Sant, Claudia E Kuehni, Michael FG Murphy, Michel P Coleman, Claudia Allemani, undefined CONCORD Working Group

Journal article  |  2017  |  The Lancet Haematology

BACKGROUND: Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme wa..

The Dose-Response Association between Nitrogen Dioxide Exposure and Serum Interleukin-6 Concentrations

Jennifer L Perret, Gayan Bowatte, Caroline J Lodge, Luke D Knibbs, Lyle C Gurrin, Rangi Kandane-Rathnayake, David P Johns, Adrian J Lowe, John A Burgess, Bruce R Thompson, Paul S Thomas, Richard Wood-Baker, Stephen Morrison, Graham G Giles, Guy Marks, James Markos, Mimi LK Tang, Michael J Abramson, E Haydn Walters, Melanie C Matheson, et al.

Journal article  |  2017  |  International Journal of Molecular Sciences

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Tongwu Zhang, Jason W Hoskins, Jiyeon Choi, Younghun Han, Mingfeng Zhang, Janelle Thomas, Michael Kovacs, Irene Collins, Marta Dzyadyk, Abbey Thompson, Maura O'Neill, Sudipto Das, Qi Lan, Roelof Koster, Rachael S Stolzenberg-Solomon, et al.

Journal article  |  2017  |  Nature Communications

Genome wide association studies (GWAS) have mapped multiple independent cancer susceptibility loci to chr5p15.33. Here, we show th..

Nonlinear relation between animal protein intake and risk of type 2 diabetes: a dose-response meta-analysis of prospective studies Reply

Xianwen Shang, David Scott, Allison M Hodge, Graham G Giles, Peter R Ebeling, Kerrie M Sanders

Journal article  |  2017  |  The American Journal of Clinical Nutrition

Genome-Wide Measures of Peripheral Blood Dna Methylation and Prostate Cancer Risk in a Prospective Nested Case-Control Study

Liesel M FitzGerald, Haroon Naeem, Enes Makalic, Daniel F Schmidt, James G Dowty, Jihoon E Joo, Chol-Hee Jung, Julie K Bassett, Pierre-Antoine Dugue, Jessica Chung, Andrew Lonie, Roger L Milne, Ee Ming Wong, John L Hopper, Dallas R English, Gianluca Severi, Laura Baglietto, John Pedersen, Graham G Giles, Melissa C Southey

Journal article  |  2017  |  The Prostate

Body Size Indicators and Risk of Gallbladder Cancer: Pooled Analysis of Individual-Level Data from 19 Prospective Cohort Studies

Peter T Campbell, Christina C Newton, Cari M Kitahara, Alpa V Patel, Patricia Hartge, Jill Koshiol, Katherine A McGlynn, Hans-Olov Adami, Amy Berrington de Gonzalez, Laura E Beane Freeman, Leslie Bernstein, Julie E Buring, Neal D Freedman, Yu-Tang Gao, Graham G Giles, Marc J Gunter, Mazda Jenab, Linda M Liao, Roger L Milne, Kim Robien, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

Longitudinal Study of Mammographic Density Measures That Predict Breast Cancer Risk

Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Julie A Simpson, Gianluca Severi, Christopher F Evans, Robert J MacInnis, Graham G Giles, Carmel Apicella, John L Hopper

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

Mammographic density defined by higher than conventional brightness thresholds better predicts breast cancer risk

Tuong L Nguyen, Ye K Aung, Christopher F Evans, Gillian S Dite, Jennifer Stone, Robert J MacInnis, James G Dowty, Adrian Bickerstaffe, Kelly Aujard, Johanna M Rommens, Yun-Mi Song, Joohon Sung, Mark A Jenkins, Melissa C Southey, Graham G Giles, Carmel Apicella, John L Hopper

Journal article  |  2017  |  International Journal of Epidemiology

Cohort Profile: The Tasmanian Longitudinal Health STUDY (TAHS)

Melanie C Matheson, Michael J Abramson, Katrina Allen, Geza Benke, John A Burgess, James G Dowty, Bircan Erbas, Iain H Feather, Peter A Frith, Graham G Giles, Lyle C Gurrin, Garun S Hamilton, John L Hopper, Alan L James, Mark A Jenkins, David P Johns, Caroline J Lodge, Adrian J Lowe, James Markos, Stephen C Morrison, et al.

Journal article  |  2017  |  International Journal of Epidemiology

Lifetime alcohol intake is associated with an increased risk of KRAS plus and BRAF-/KRAS- but not BRAF plus colorectal cancer

Harindra Jayasekara, Robert J MacInnis, Elizabeth J Williamson, Allison M Hodge, Mark Clendenning, Christophe Rosty, Rhiannon Walters, Robin Room, Melissa C Southey, Mark A Jenkins, Roger L Milne, John L Hopper, Graham G Giles, Daniel D Buchanan, Dallas R English

Journal article  |  2017  |  International Journal of Cancer

HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women

Charles D Warne, Sophie G Zaloumis, Nadine A Bertalli, Martin B Delatycki, Amanda J Nicoll, Christine E McLaren, John L Hopper, Graham G Giles, Greg J Anderson, John K Olynyk, Lawrie W Powell, Katrina J Allen, Lyle C Gurrin

Journal article  |  2017  |  Journal of Gastroenterology and Hepatology

Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.

Verena Zuber, Francesco Bettella, Aree Witoelar, undefined PRACTICAL Consortium, undefined CRUK GWAS, undefined BCAC Consortium, undefined TRICL Consortium, Ole A Andreassen, Ian G Mills, Alfonso Urbanucci

Journal article  |  2017  |  BMC Genomics

BACKGROUND: Epigenetic information can be used to identify clinically relevant genomic variants single nucleotide polymorphisms (S..

Socioeconomic status and the 25 x 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1.7 million men and women

Silvia Stringhini, Cristian Carmeli, Markus Jokela, Mauricio Avendano, Peter Muennig, Florence Guida, Fulvio Ricceri, Angelo d'Errico, Henrique Barros, Murielle Bochud, Marc Chadeau-Hyam, Francoise Clavel-Chapelon, Giuseppe Costa, Cyrille Delpierre, Silvia Fraga, Marcel Goldberg, Graham G Giles, Vittorio Krogh, Michelle Kelly-Irving, Richard Layte, et al.

Journal article  |  2017  |  The Lancet

Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry

Logan C Walker, John F Pearson, George AR Wiggins, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2017  |  Breast Cancer Research

Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer

Gillian S Dite, Robert J MacInnis, Adrian Bickerstaffe, James G Dowty, Roger L Milne, Antonis C Antoniou, Prue Weideman, Carmel Apicella, Graham G Giles, Melissa C Southey, Mark A Jenkins, Kelly-Anne Phillips, Aung Ko Win, Mary Beth Terry, John L Hopper

Journal article  |  2017  |  American Journal of Epidemiology

SNP interaction pattern identifier (SIPI): an intensive search for SNP-SNP interaction patterns

Hui-Yi Lin, Dung-Tsa Chen, Po-Yu Huang, Yung-Hsin Liu, Augusto Ochoa, Jovanny Zabaleta, Donald E Mercante, Zhide Fang, Thomas A Sellers, Julio M Pow-Sang, Chia-Ho Cheng, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Gronberg, et al.

Journal article  |  2017  |  Bioinformatics

The interaction between farming/rural environment and TLR2, TLR4, TLR6 and CD14 genetic polymorphisms in relation to early- and late-onset asthma

Melisa YZ Lau, Shyamali C Dharmage, John A Burgess, Aung K Win, Adrian J Lowe, Caroline Lodge, Jennifer Perret, Jennie Hui, Paul S Thomas, Stephen Morrison, Graham G Giles, John Hopper, Michael J Abramson, E Haydn Walters, Melanie C Matheson

Journal article  |  2017  |  Scientific Reports

Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Dennis J Ahnen, Stephen N Thibodeau, Graham Casey, Steven Gallinger, Loic Le Marchand, Robert W Haile, John D Potter, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers

S Ghazaleh Dashti, Daniel D Buchanan, Harindra Jayasekara, Driss Ait Ouakrim, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Susan Parry, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Early menarche, nulliparity and the risk for premature and early natural menopause

Gita D Mishra, Nirmala Pandeya, Annette J Dobson, Hsin-Fang Chung, Debra Anderson, Diana Kuh, Sven Sandin, Graham G Giles, Fiona Bruinsma, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, Janet E Cade, Victoria Burley, Darren C Greenwood, Alissa Goodman, Mette Kildevld Simonsen, Hans-Olov Adami, Panayotes Demakakos, Elisabete Weiderpass

Journal article  |  2017  |  Human Reproduction

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Phillip J Law, Sonja I Berndt, Helen E Speedy, Nicola J Camp, Georgina P Sava, Christine F Skibola, Amy Holroyd, Vijai Joseph, Nicola J Sunter, Alexandra Nieters, Silvia Bea, Alain Monnereau, David Martin-Garcia, Lynn R Goldin, Guillem Clot, Lauren R Teras, Ines Quintela, Brenda M Birmann, Sandrine Jayne, Wendy Cozen, et al.

Journal article  |  2017  |  Nature Communications

Dietary quality is associated with abdominal aortic calcification: A mean of 18-year longitudinal study in community-dwelling older adults

X Shang, D Scott, A Hodge, B Khan, N Khan, DR English, GG Giles, PR Ebeling, KM Sanders

Journal article  |  2017  |  The journal of nutrition, health & aging

Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts

Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Stine V Eriksen, Michael D Walsh, Rhiannon J Walters, Stephen N Thibodeau, Jenna Stewart, Susan Preston, Aung Ko Win, Louisa Flander, Driss Ait Ouakrim, Finlay A Macrae, Alex Boussioutas, Ingrid M Winship, Graham G Giles, John L Hopper, Melissa C Southey, Dallas English, Mark A Jenkins

Journal article  |  2017  |  Journal of Gastroenterology and Hepatology

Inflammatory Cytokines and Lung Cancer Risk in 3 Prospective Studies

Darren R Brenner, Anouar Fanidi, Kjell Grankvist, David C Muller, Paul Brennan, Jonas Manjer, Graham Byrnes, Allison Hodge, Gianluca Severi, Graham G Giles, Mikael Johansson, Mattias Johansson

Journal article  |  2017  |  American Journal of Epidemiology

Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis

Amy E Taylor, Richard M Martin, Milan S Geybels, Janet L Stanford, Irene Shui, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, Borge G Nordestgaard, Ruth C Travis, David Neal, Nora Pashayan, et al.

Journal article  |  2017  |  International Journal of Cancer

Characterisation of microbial communities within aggressive prostate cancer tissues

Melissa A Yow, Sepehr N Tabrizi, Gianluca Severi, Damien M Bolton, John Pedersen, Australian Prostate, Graham G Giles, Melissa C Southey

Journal article  |  2017  |  Infectious Agents and Cancer

Development of an Australian cardiovascular disease mortality risk score using multiple imputation and recalibration from national statistics

Kathryn Backholer, Yoichiro Hirakawa, Andrew Tonkin, Graham Giles, Dianna J Magliano, Stephen Colagiuri, Mark Harris, Paul Mitchell, Mark Nelson, Jonathan E Shaw, David Simmons, Leon Simons, Anne Taylor, Jessica Harding, Bamini Gopinath, Mark Woodward

Journal article  |  2017  |  BMC Cardiovascular Disorders

Preterm birth and low birth weight continue to increase the risk of asthma from age 7 to 43

Melanie C Matheson, Ana Lopez-Polin D'Olhaberriague, John A Burgess, Graham G Giles, John L Hopper, David P Johns, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage

Journal article  |  2017  |  Journal of Asthma

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

Christopher I Amos, Joe Dennis, Zhaoming Wang, Jinyoung Byun, Fredrick R Schumacher, Simon A Gayther, Graham Casey, David J Hunter, Thomas A Sellers, Stephen B Gruber, Alison M Dunning, Kyriaki Michailidou, Laura Fachal, Kimberly Doheny, Amanda B Spurdle, Yafang Li, Xiangjun Xiao, Jane Romm, Elizabeth Pugh, Gerhard A Coetzee, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers & Prevention

The biology of inequalities in health: the LIFEPATH project

Paolo Vineis, Mauricio Avendano-Pabon, Henrique Barros, Marc Chadeau-Hyam, Giuseppe Costa, Michaela Dijmarescu, Cyrille Delpierre, Angelo D'Errico, Silvia Fraga, Graham Giles, Marcel Goldberg, Marie Zins, Michelle Kelly-Irving, Mika Kivimaki, Thierry Lang, Richard Layte, Johan P Mackenbach, Michael Marmot, Cathal McCrory, Cristian Carmeli, et al.

Journal article  |  2017  |  Longitudinal and Life Course Studies

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

Clair Brunner, Neil M Davies, Richard M Martin, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham Giles, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, Borge G Nordestgaard, Ruth C Travis, David Neal, Jenny Donovan, Freddie C Hamdy, Nora Pashayan, et al.

Journal article  |  2017  |  International Journal of Cancer

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

Laura Baglietto, Erica Ponzi, Philip Haycock, Allison Hodge, Manuela Bianca Assumma, Chol-Hee Jung, Jessica Chung, Francesca Fasanelli, Florence Guida, Gianluca Campanella, Marc Chadeau-Hyam, Kjell Grankvist, Mikael Johansson, Ugo Ala, Paolo Provero, Ee Ming Wong, Jihoon Joo, Dallas R English, Nabila Kazmi, Eiliv Lund, et al.

Journal article  |  2017  |  International Journal of Cancer

Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age

Gayan Bowatte, Caroline J Lodge, Luke D Knibbs, Adrian J Lowe, Bircan Erbas, Martine Dennekamp, Guy B Marks, Graham Giles, Stephen Morrison, Bruce Thompson, Paul S Thomas, Jennie Hui, Jennifer L Perret, Michael J Abramson, Haydn Walters, Melanie C Matheson, Shyamali C Dharmage

Journal article  |  2017  |  Journal of Allergy and Clinical Immunology

Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma

Sasha Bernatsky, Hector A Velasquez Garcia, John J Spinelli, Patrick Gaffney, Karin E Smedby, Rosalind Ramsey-Goldman, Sophia S Wang, Hans-Olov Adami, Demetrius Albanes, Emanuele Angelucci, Stephen M Ansell, Yan W Asmann, Nikolaus Becker, Yolanda Benavente, Sonja I Berndt, Kimberly A Bertrand, Brenda M Birmann, Heiner Boeing, Paolo Boffetta, Paige M Bracci, et al.

Journal article  |  2017  |  Lupus Science & Medicine

Occupational exposures to solvents and metals are associated with fixed airflow obstruction

Sheikh M Alif, Shyamali C Dharmage, Geza Benke, Martine Dennekamp, John A Burgess, Jennifer L Perret, Caroline J Lodge, Stephen Morrison, David P Johns, Graham G Giles, Lyle C Gurrin, Paul S Thomas, John L Hopper, Richard Wood-Baker, Bruce R Thompson, Iain H Feather, Roel Vermeulen, Hans Kromhout, E Haydn Walters, Michael J Abramson, et al.

Journal article  |  2017  |  Scandinavian Journal of Work, Environment and Health

Causes of blood methylomic variation for middle-aged women measured by the HumanMethylation450 array

Shuai Li, Ee Ming Wong, Tuong L Nguyen, Ji-Hoon Eric Joo, Jennifer Stone, Gillian S Dite, Graham G Giles, Richard Saffery, Melissa C Southey, John L Hopper

Journal article  |  2017  |  Epigenetics

Mammographic density assessed on paired raw and processed digital images and on paired screen-film and digital images across three mammography systems

Anya Burton, Graham Byrnes, Jennifer Stone, Rulla M Tamimi, John Heine, Celine Vachon, Vahit Ozmen, Ana Pereira, Maria Luisa Garmendia, Christopher Scott, John H Hipwell, Caroline Dickens, Joachim Schuz, Mustafa Erkin Aribal, Kimberly Bertrand, Ava Kwong, Graham G Giles, John Hopper, Beatriz Perez Gomez, Marina Pollan, et al.

Journal article  |  2016  |  Breast Cancer Research

Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21

Yosr Hamdi, Penny Soucy, Veronique Adoue, Kyriaki Michailidou, Sander Canisius, Audrey Lemacon, Arnaud Droit, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Caroline Baynes, Carl Blomqvist, Natalia V Bogdanova, Stig E Bojesen, Manjeet K Bolla, Bernardo Bonanni, Anne-Lise Borresen-Dale, Judith S Brand, Hiltrud Brauch, Hermann Brenner, et al.

Journal article  |  2016  |  Oncotarget

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Melissa C Southey, David E Goldgar, Robert Winqvist, Katri Pylkas, Fergus Couch, Marc Tischkowitz, William D Foulkes, Joe Dennis, Kyriaki Michailidou, Elizabeth J van Rensburg, Tuomas Heikkinen, Heli Nevanlinna, John L Hopper, Thilo Doerk, Kathleen BM Claes, Jorge Reis-Filho, Zhi Ling Teo, Paolo Radice, Irene Catucci, Paolo Peterlongo, et al.

Journal article  |  2016  |  Journal of Medical Genetics

Mould-sensitized adults have lower Th2 cytokines and a higher prevalence of asthma than those sensitized to other aeroallergens

MC Matheson, JC Reece, RK Kandane-Rathnayake, MLK Tang, JA Simpson, IH Feather, MC Southey, H Tsimiklis, JL Hopper, SC Morrison, GG Giles, EH Walters, SC Dharmage

Journal article  |  2016  |  Allergy

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci

Kristin A Rand, Chi Song, Eric Dean, Daniel J Serie, Karen Curtin, Xin Sheng, Donglei Hu, Carol Ann Huff, Leon Bernal-Mizrachi, Michael H Tomasson, Sikander Ailawadhi, Seema Singhal, Karen Pawlish, Edward S Peters, Cathryn H Bock, Alex Stram, David J Van den Berg, Christopher K Edlund, David V Conti, Todd Zimmerman, et al.

Journal article  |  2016  |  Cancer Epidemiology Biomarkers & Prevention

Use of a Novel Nonparametric Version of DEPTH to Identify Genomic Regions Associated with Prostate Cancer Risk

Robert J MacInnis, Daniel F Schmidt, Enes Makalic, Gianluca Severi, Liesel M FitzGerald, Matthias Reumann, Miroslaw K Kapuscinski, Adam Kowalczyk, Zeyu Zhou, Benjamin Goudey, Guoqi Qian, Quang M Bui, Daniel J Park, Adam Freeman, Melissa C Southey, Ali Amin Al Olama, Zsofia Kote-Jarai, Rosalind A Eeles, John L Hopper, Graham G Giles

Journal article  |  2016  |  Cancer Epidemiology Biomarkers & Prevention

Investigation of bias related to differences between case and control interview dates in five INTERPHONE countries

Michelle C Turner, Siegal Sadetzki, Chelsea E Langer, Rodrigo Villegas, Jordi Figuerola, Bruce K Armstrong, Angela Chetrit, Graham G Giles, Daniel Krewski, Martine Hours, Mary L McBride, Marie-Elise Parent, Lesley Richardson, Jack Siemiatycki, Alistair Woodward, Elisabeth Cardis

Journal article  |  2016  |  Annals of Epidemiology

Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry

Cameron M Scott, JiHoon Eric Joo, Neil O'Callaghan, Daniel D Buchanan, Mark Clendenning, Graham G Giles, John L Hopper, Ee Ming Wong, Melissa C Southey

Journal article  |  2016  |  PLOS ONE

rs2735383, located at a microRNA binding site in the 3 ' UTR of NBS1, is not associated with breast cancer risk

Jingjing Liu, Ivona Loncar, J Margriet Collee, Manjeet K Bolla, Joe Dennis, Kyriaki Michailidou, Qin Wang, Irene L Andrulis, Monica Barile, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Carl Blomqvist, Bram Boeckx, Natalia V Bogdanova, Stig E Bojesen, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Annegien Broeks, et al.

Journal article  |  2016  |  Scientific Reports

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

Jennifer B Permuth, Brett Reid, Madalene Earp, Y Ann Chen, Alvaro NA Monteiro, Zhihua Chen, Georgia Chenevix-Trench, Peter A Fasching, Matthias W Beckmann, Diether Lambrechts, Adriaan Vanderstichele, Els Van Niewenhuyse, Ignace Vergote, Mary Anne Rossing, Jennifer Anne Doherty, Jenny Chang-Claude, Kirsten Moysich, Kunle Odunsi, Marc T Goodman, Yurii B Shvetsov, et al.

Journal article  |  2016  |  Oncotarget

Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist: Hip Ratio, Is Causal for Endometrial Cancer

Jodie N Painter, Tracy A O'Mara, Louise Marquart, Penelope M Webb, John Attia, Sarah E Medland, Timothy Cheng, Joe Dennis, Elizabeth G Holliday, Mark McEvoy, Rodney J Scott, Shahana Ahmed, Catherine S Healey, Mitul Shah, Maggie Gorman, Lynn Martin, Shirley V Hodgson, Matthias W Beckmann, Arif B Ekici, Peter A Fasching, et al.

Journal article  |  2016  |  Cancer Epidemiology Biomarkers & Prevention

Analysis of the breast cancer methylome using formalin-fixed paraffin-embedded tumour

Ee Ming Wong, JiHoon E Joo, Catriona A McLean, Laura Baglietto, Dallas R English, Gianluca Severi, Hui-Chen Wu, Mary Beth Terry, John L Hopper, Roger L Milne, Graham G Giles, Melissa C Southey

Journal article  |  2016  |  Breast Cancer Research and Treatment

Clinical and functional differences between early-onset and late-onset adult asthma: a population-based Tasmanian Longitudinal Health Study

Daniel J Tan, E Haydn Walters, Jennifer L Perret, John A Burgess, David P Johns, Adrian J Lowe, Caroline J Lodge, Panteha Hayati Rezvan, Julie A Simpson, Stephen Morrison, Bruce R Thompson, Paul S Thomas, Iain Feather, Graham G Giles, John L Hopper, Michael J Abramson, Melanie C Matheson, Shyamali C Dharmage

Journal article  |  2016  |  Thorax

Dietary protein intake and risk of type 2 diabetes: results from the Melbourne Collaborative Cohort Study and a meta-analysis of prospective studies

Xianwen Shang, David Scott, Allison M Hodge, Dallas R English, Graham G Giles, Peter R Ebeling, Kerrie M Sanders

Journal article  |  2016  |  The American Journal of Clinical Nutrition

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

Shalaka S Hampras, Lara E Sucheston-Campbell, Rikki Cannioto, Jenny Chang-Claude, Francesmary Modugno, Thilo Doerk, Peter Hillemanns, Leah Preus, Keith L Knutson, Paul K Wallace, Chi-Chen Hong, Grace Friel, Warren Davis, Mary Nesline, Celeste L Pearce, Linda E Kelemen, Marc T Goodman, Elisa V Bandera, Kathryn L Terry, Nils Schoof, et al.

Journal article  |  2016  |  Oncotarget

Prostate Cancer

GG Giles

Book Chapter  |  2016

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

Maya Ghoussaini, Juliet D French, Kyriaki Michailidou, Silje Nord, Jonathan Beesley, Sander Canisus, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Mandi Moradi Marjaneh, Jason S Lee, Joe Dennis, Manjeet K Bolla, Qin Wang, Ed Dicks, Roger L Milne, John L Hopper, Melissa C Southey, Marjanka K Schmidt, Annegien Broeks, et al.

Journal article  |  2016  |  The American Journal of Human Genetics

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Nilah M Ioannidis, Joseph H Rothstein, Vikas Pejaver, Sumit Middha, Shannon K McDonnell, Saurabh Baheti, Anthony Musolf, Qing Li, Emily Holzinger, Danielle Karyadi, Lisa A Cannon-Albright, Craig C Teerlink, Janet L Stanford, William B Isaacs, Jianfeng Xu, Kathleen A Cooney, Ethan M Lange, Johanna Schleutker, John D Carpten, Isaac J Powell, et al.

Journal article  |  2016  |  The American Journal of Human Genetics

Low Relative Lean Mass is Associated with Increased Likelihood of Abdominal Aortic Calcification in Community-Dwelling Older Australians

Alexander J Rodriguez, David Scott, Belal Khan, Nayab Khan, Allison Hodge, Dallas R English, Graham G Giles, Peter R Ebeling

Journal article  |  2016  |  Calcified Tissue International

Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States

Paige Maas, Myrto Barrdahl, Amit D Joshi, Paul L Auer, Mia M Gaudet, Roger L Milne, Fredrick R Schumacher, William F Anderson, David Check, Subham Chattopadhyay, Laura Baglietto, Christine D Berg, Stephen J Chanock, David G Cox, Jonine D Figueroa, Mitchell H Gail, Barry I Graubard, Christopher A Haiman, Susan E Hankinson, Robert N Hoover, et al.

Journal article  |  2016  |  JAMA Oncology

The InterLACE study: Design, data harmonization and characteristics across 20 studies on women's health

Gita D Mishra, Hsin-Fang Chung, Nirmala Pandeya, Annette J Dobson, Lee Jones, Nancy E Avis, Sybil L Crawford, Ellen B Gold, Daniel Brown, Lynette L Sievert, Eric Brunner, Janet E Cade, Victoria J Burley, Darren C Greenwood, Graham G Giles, Fiona Bruinsma, Alissa Goodman, Kunihiko Hayashi, Jung Su Lee, Hideki Mizunuma, et al.

Journal article  |  2016  |  Maturitas

Past physical activity and age-related macular degeneration: the Melbourne Collaborative Cohort Study

Myra B McGuinness, Amalia Karahalios, Julie A Simpson, Robyn H Guymer, Luba D Robman, Allison M Hodge, Ester Cerin, Graham G Giles, Robert P Finger

Journal article  |  2016  |  British Journal of Ophthalmology

Association Between Dietary Intake of Antioxidants and Prevalence of Femoral Head Cartilage Defects and Bone Marrow Lesions in Community-based Adults

Yuanyuan Wang, Sam Smith, Andrew J Teichtahl, Allison M Hodge, Anita Wluka, Graham G Giles, Flavia M Cicuttini

Journal article  |  2016  |  The Journal of Rheumatology

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

Carolina Bonilla, Sarah J Lewis, Mari-Anne Rowlands, Tom R Gaunt, George Davey Smith, David Gunnell, Tom Palmer, Jenny L Donovan, Freddie C Hamdy, David E Neal, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Groenberg, Christopher A Haiman, et al.

Journal article  |  2016  |  International Journal of Cancer

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

Jue-Sheng Ong, Gabriel Cuellar-Partida, Yi Lu, Peter A Fasching, Alexander Hein, Stefanie Burghaus, Matthias W Beckmann, Diether Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Adriaan Vanderstichele, Jennifer Anne Doherty, Mary Anne Rossing, Jenny Chang-Claude, Ursula Eilber, Anja Rudolph, Shan Wang-Gohrke, Marc T Goodman, Natalia Bogdanova, Thilo Dork, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

Jiajun Shi, Yanfeng Zhang, Wei Zheng, Kyriaki Michailidou, Maya Ghoussaini, Manjeet K Bolla, Qin Wang, Joe Dennis, Michael Lush, Roger L Milne, Xiao-Ou Shu, Jonathan Beesley, Siddhartha Kar, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Zhiguo Zhao, Xingyi Guo, Javier Benitez, et al.

Journal article  |  2016  |  International Journal of Cancer

Association between selected dietary scores and the risk of urothelial cell carcinoma: A prospective cohort study

Pierre-Antoine Dugue, Allison M Hodge, Maree T Brinkman, Julie K Bassett, Nitin Shivappa, James R Hebert, John L Hopper, Dallas R English, Roger L Milne, Graham G Giles

Journal article  |  2016  |  International Journal of Cancer

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)

Hatef Darabi, Jonathan Beesley, Arnaud Droit, Siddhartha Kar, Silje Nord, Mahdi Moradi Marjaneh, Penny Soucy, Kyriaki Michailidou, Maya Ghoussaini, Hanna Fues Wahl, Manjeet K Bolla, Qin Wang, Joe Dennis, M Rosario Alonso, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Javier Benitez, Natalia V Bogdanova, et al.

Journal article  |  2016  |  Scientific Reports

Validity and calibration of the FFQ used in the Melbourne Collaborative Cohort Study

Julie K Bassett, Dallas R English, Michael T Fahey, Andrew B Forbes, Lyle C Gurrin, Julie A Simpson, Maree T Brinkman, Graham G Giles, Allison M Hodge

Journal article  |  2016  |  PUBLIC HEALTH NUTRITION

Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in community-dwelling older adults

Xianwen Shang, David Scott, Allison Hodge, Belal Khan, Nayab Khan, Dallas R English, Graham G Giles, Peter R Ebeling, Kerrie M Sanders

Journal article  |  2016  |  The International Journal of Cardiovascular Imaging

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression

Asaf Wyszynski, Chi-Chen Hong, Kristin Lam, Kyriaki Michailidou, Christian Lytle, Song Yao, Yali Zhang, Manjeet K Bolla, Qin Wang, Joe Dennis, John L Hopper, Melissa C Southey, Marjanka K Schmidt, Annegien Broeks, Kenneth Muir, Artitaya Lophatananon, Peter A Fasching, Matthias W Beckmann, Julian Peto, Isabel dos-Santos-Silva, et al.

Journal article  |  2016  |  Human Molecular Genetics

Is breast cancer risk associated with alcohol intake before first full-term pregnancy?

Harindra Jayasekara, Robert J MacInnis, Allison M Hodge, Robin Room, Roger L Milne, John L Hopper, Graham G Giles, Dallas R English

Journal article  |  2016  |  Cancer Causes & Control

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

Nicholas B Larson, Shannon McDonnell, Lisa Cannon Albright, Craig Teerlink, Janet Stanford, Elaine A Ostrander, William B Isaacs, Jianfeng Xu, Kathleen A Cooney, Ethan Lange, Johanna Schleutker, John D Carpten, Isaac Powell, Joan Bailey-Wilson, Olivier Cussenot, Geraldine Cancel-Tassin, Graham Giles, Robert MacInnis, Christiane Maier, Alice S Whittemore, et al.

Journal article  |  2016  |  Genetic Epidemiology

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Christophe Rosty, S Ghazaleh Dashti, Driss Ait Ouakrim, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Graham G Giles, Dennis J Ahnen, Jan Lowery, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Susan Parry, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: a prospective nested case-control study

Pierre-Antoine Dugue, Maree T Brinkman, Roger L Milne, Ee Ming Wong, Liesel M FitzGerald, Julie K Bassett, Jihoon E Joo, Chol-Hee Jung, Enes Makalic, Daniel F Schmidt, Daniel J Park, Jessica Chung, Anthony D Ta, Damien M Bolton, Andrew Lonie, Anthony Longano, John L Hopper, Gianluca Severi, Richard Saffery, Dallas R English, et al.

Journal article  |  2016  |  British Journal of Cancer

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

Siddhartha P Kar, Jonathan Beesley, Ali Amin Al Olama, Kyriaki Michailidou, Jonathan Tyrer, Zsofi A Kote-Jarai, Kate Lawrenson, Sara Lindstrom, Susan J Ramus, Deborah J Thompson, Adam S Kibel, Agnieszka Dansonka-Mieszkowska, Agnieszka Michael, Aida K Dieffenbach, Aleksandra Gentry-Maharaj, Alice S Whittemore, Alicja Wolk, Alvaro Monteiro, Ana Peixoto, Andrzej Kierzek, et al.

Journal article  |  2016  |  Cancer Discovery

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

Nikhil K Khankari, Xiao-Ou Shu, Wanqing Wen, Peter Kraft, Sara Lindstrom, Ulrike Peters, Joellen Schildkraut, Fredrick Schumacher, Paolo Bofetta, Angela Risch, Heike Bickeboeller, Christopher I Amos, Douglas Easton, Rosalind A Eeles, Stephen B Gruber, Christopher A Haiman, David J Hunter, Stephen J Chanock, Brandon L Pierce, Wei Zheng

Journal article  |  2016  |  PLOS Medicine

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

Kate Lawrenson, Siddhartha Kar, Karen McCue, Karoline Kuchenbaeker, Kyriaki Michailidou, Jonathan Tyrer, Jonathan Beesley, Susan J Ramus, Qiyuan Li, Melissa K Delgado, Janet M Lee, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Banu K Arun, Brita Arver, Elisa V Bandera, Monica Barile, Rosa B Barkardottir, et al.

Journal article  |  2016  |  Nature Communications

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

Hisani N Horne, Charles C Chung, Han Zhang, Kai Yu, Ludmila Prokunina-Olsson, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, John L Hopper, Melissa C Southey, Marjanka K Schmidt, Annegien Broeks, Kenneth Muir, Artitaya Lophatananon, Peter A Fasching, Matthias W Beckmann, Olivia Fletcher, Nichola Johnson, Elinor J Sawyer, et al.

Journal article  |  2016  |  PLOS ONE

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

Nikhil K Khankari, Harvey J Murff, Chenjie Zeng, Wanqing Wen, Rosalind A Eeles, Douglas F Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, Borge G Nordestgaard, Ruth C Travis, Jenny L Donovan, Nora Pashayan, Kay-Tee Khaw, et al.

Journal article  |  2016  |  British Journal of Cancer

Age- and Tumor Subtype Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

Marjanka K Schmidt, Frans Hogervorst, Richard van Hien, Sten Cornelissen, Annegien Broeks, Muriel A Adank, Hanne Meijers, Quinten Waisfisz, Antoinette Hollestelle, Mieke Schutte, Ans van den Ouweland, Maartje Hooning, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Antonis C Antoniou, Volker Arndt, Marina Bermisheva, Natalia V Bogdanova, Manjeet K Bolla, et al.

Journal article  |  2016  |  Journal of Clinical Oncology

Relationship between circulating sex steroid hormone concentrations and incidence of total knee and hip arthroplasty due to osteoarthritis in men

SM Hussain, Flavia M Cicuttini, GG Giles, SE Graves, Y Wang

Journal article  |  2016  |  Osteoarthritis and Cartilage

omega-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease Pooling Project of 19 Cohort Studies

Liana C Del Gobbo, Fumiaki Imamura, Stella Aslibekyan, Matti Marklund, Jyrki K Virtanen, Maria Wennberg, Mohammad Y Yakoob, Stephanie E Chiuve, Luicito dela Cruz, Alexis C Frazier-Wood, Amanda M Fretts, Eliseo Guallar, Chisa Matsumoto, Kiesha Prem, Tosh Tanaka, Jason HY Wu, Xia Zhou, Catherine Helmer, Erik Ingelsson, Jian-Min Yuan, et al.

Journal article  |  2016  |  JAMA Internal Medicine

Development and External Validation of a Melanoma Risk Prediction Model Based on Self-assessed Risk Factors

Kylie Vuong, Bruce K Armstrong, Elisabete Weiderpass, Eiliv Lund, Hans-Olov Adami, Marit B Veierod, Jennifer H Barrett, John R Davies, D Timothy Bishop, David C Whiteman, Catherine M Olsen, John L Hopper, Graham J Mann, Anne E Cust, Kevin McGeechan

Journal article  |  2016  |  JAMA Dermatology

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21

Craig C Teerlink, Daniel Leongamornlert, Tokhir Dadaev, Alun Thomas, James Farnham, Robert A Stephenson, Shaun Riska, Shannon K McDonnell, Daniel J Schaid, William J Catalona, S Lilly Zheng, Kathleen A Cooney, Anna M Ray, Kimberly A Zuhlke, Ethan M Lange, Graham G Giles, Melissa C Southey, Liesel M Fitzgerald, Antje Rinckleb, Manuel Luedeke, et al.

Journal article  |  2016  |  Human Genetics

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

Yan Guo, Shaneda Warren Andersen, Xiao-Ou Shu, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Montserrat Garcia-Closas, Roger L Milne, Marjanka K Schmidt, Jenny Chang-Claude, Allison Dunning, Stig E Bojesen, Habibul Ahsan, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, et al.

Journal article  |  2016  |  PLOS Medicine

Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status

Jie Shang, Jeanette C Reece, Daniel D Buchanan, Graham G Giles, Jane C Figueiredo, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  International Journal of Colorectal Disease

Reliability of DNA methylation measures from dried blood spots and mononuclear cells using the HumanMethylation450k BeadArray

Pierre-Antoine Dugue, Dallas R English, Robert J MacInnis, Chol-Hee Jung, Julie K Bassett, Liesel M FitzGerald, Ee Ming Wong, Jihoon E Joo, John L Hopper, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2016  |  Scientific Reports

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes

Gabriel Cuellar-Partida, Yi Lu, Suzanne C Dixon, Peter A Fasching, Alexander Hein, Stefanie Burghaus, Matthias W Beckmann, Diether Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Adriaan Vanderstichele, Jennifer Anne Doherty, Mary Anne Rossing, Jenny Chang-Claude, Anja Rudolph, Shan Wang-Gohrke, Marc T Goodman, Natalia Bogdanova, Thilo Doerk, Matthias Duerst, et al.

Journal article  |  2016  |  Human Genetics

Dietary inflammatory index, Mediterranean diet score, and lung cancer: a prospective study

AM Hodge, JK Bassett, N Shivappa, JR Hebert, DR English, GG Giles, G Severi

Journal article  |  2016  |  Cancer Causes & Control

Mother's smoking and complex lung function of offspring in middle age: A cohort study from childhood

Jennifer L Perret, Haydn Walters, David Johns, Lyle Gurrin, John Burgess, Adrian Lowe, Bruce Thompson, James Markos, Stephen Morrison, Paul Thomas, Christine McDonald, Richard Wood-Baker, John Hopper, Cecilie Svanes, Graham Giles, Michael Abramson, Melanie Matheson, Shyamali Dharmage

Journal article  |  2016  |  Respirology

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

Chenjie Zeng, Xingyi Guo, Jirong Long, Karoline B Kuchenbaecker, Arnaud Droit, Kyriaki Michailidou, Maya Ghoussaini, Siddhartha Kar, Adam Freeman, John L Hopper, Roger L Milne, Manjeet K Bolla, Qin Wang, Joe Dennis, Simona Agata, Shahana Ahmed, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, et al.

Journal article  |  2016  |  Breast Cancer Research

Mammographic density and risk of breast cancer by mode of detection and tumor size: a case-control study

Kavitha Krishnan, Laura Baglietto, Carmel Apicella, Jennifer Stone, Melissa C Southey, Dallas R English, Graham G Giles, John L Hopper

Journal article  |  2016  |  Breast Cancer Research

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

Mitchell J Machiela, Weiyin Zhou, Eric Karlins, Joshua N Sampson, Neal D Freedman, Qi Yang, Belynda Hicks, Casey Dagnall, Christopher Hautman, Kevin B Jacobs, Christian C Abnet, Melinda C Aldrich, Christopher Amos, Laufey T Amundadottir, Alan A Arslan, Laura E Beane-Freeman, Sonja I Berndt, Amanda Black, William J Blot, Cathryn H Bock, et al.

Journal article  |  2016  |  NATURE COMMUNICATIONS

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

Mitchell J Machiela, Weiyin Zhou, Eric Karlins, Joshua N Sampson, Neal D Freedman, Qi Yang, Belynda Hicks, Casey Dagnall, Christopher Hautman, Kevin B Jacobs, Christian C Abnet, Melinda C Aldrich, Christopher Amos, Laufey T Amundadottir, Alan A Arslan, Laura E Beane-Freeman, Sonja I Berndt, Amanda Black, William J Blot, Cathryn H Bock, et al.

Journal article  |  2016  |  Nature Communications

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Rowena Chau, Seyedeh Ghazaleh Dashti, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Finlay A Macrae, Alex Boussioutas, Susan Parry, Jane C Figueiredo, A Joan Levine, Dennis J Ahnen, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Five endometrial cancer risk loci identified through genome-wide association analysis

Timothy HT Cheng, Deborah J Thompson, Tracy A O'Mara, Jodie N Painter, Dylan M Glubb, Susanne Flach, Annabelle Lewis, Juliet D French, Luke Freeman-Mills, David Church, Maggie Gorman, Lynn Martin, Shirley Hodgson, Penelope M Webb, John Attia, Elizabeth G Holliday, Mark McEvoy, Rodney J Scott, Anjali K Henders, Nicholas G Martin, et al.

Journal article  |  2016  |  Nature Genetics

Blood lipids and prostate cancer: a Mendelian randomization analysis

Caroline J Bull, Carolina Bonilla, Jeff MP Holly, Claire M Perks, Neil Davies, Philip Haycock, Oriana Hoi Yun Yu, J Brent Richards, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Robert J MacInnis, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, et al.

Journal article  |  2016  |  Cancer Medicine

Combined genetic and splicing analysis of BRCA1 c.[594-2A > C; 641A > G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms

Miguel de la Hoya, Omar Soukarieh, Irene Lopez-Perolio, Ana Vega, Logan C Walker, Yvette van Ierland, Diana Baralle, Marta Santamarina, Vanessa Lattimore, Juul Wijnen, Philip Whiley, Ana Blanco, Michela Raponi, Jan Hauke, Barbara Wappenschmidt, Alexandra Becker, Thomas VO Hansen, Raquel Behar, Diether Niederacher, Norbert Arnold, et al.

Journal article  |  2016  |  Human Molecular Genetics

The impact of body mass index on the associations of lipids with the risk of coronary heart disease in the Asia Pacific region.

Yoichiro Hirakawa, Tai-Hing Lam, Timothy Welborn, Hyeon Chang Kim, Suzanne Ho, Xianghua Fang, Hirotsugu Ueshima, Il Suh, Graham Giles, Mark Woodward, undefined Asia Pacific Cohort Studies Collaboration

Journal article  |  2016  |  Preventive Medicine Reports

OBJECTIVE: To assess whether body mass index (BMI) modifies the associations of lipids with coronary heart disease (CHD). METHODS:..

Plasma phospholipids fatty acids, dietary fatty acids, and breast cancer risk

Julie K Bassett, Allison M Hodge, Dallas R English, Robert J MacInnis, Graham G Giles

Journal article  |  2016  |  Cancer Causes & Control

Alcohol consumption and breast cancer risk by estrogen receptor status: in a pooled analysis of 20 studies

Seungyoun Jung, Molin Wang, Kristin Anderson, Laura Baglietto, Leif Bergkvist, Leslie Bernstein, Piet A van den Brandt, Louise Brinton, Julie E Buring, A Heather Eliassen, Roni Falk, Susan M Gapstur, Graham G Giles, Gary Goodman, Judith Hoffman-Bolton, Pamela L Horn-Ross, Manami Inoue, Laurence N Kolonel, Vittorio Krogh, Marie Lof, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study

Suzanne C Dixon, Christina M Nagle, Aaron P Thrift, Paul DP Pharoah, Celeste Leigh Pearce, Wei Zheng, Jodie N Painter, Georgia Chenevix-Trench, Peter A Fasching, Matthias W Beckmann, Diether Lambrechts, Ignace Vergote, Sandrina Lambrechts, Els Van Nieuwenhuysen, Mary Anne Rossing, Jennifer A Doherty, Kristine G Wicklund, Jenny Chang-Claude, Anja Rudolph, Kirsten B Moysich, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies

Kana Wu, Donna Spiegelman, Tao Hou, Demetrius Albanes, Naomi E Allen, Sonja I Berndt, Piet A van den Brandt, Graham G Giles, Edward Giovannucci, R Alexandra Goldbohm, Gary G Goodman, Phyllis J Goodman, Niclas Hakansson, Manami Inoue, Timothy J Key, Laurence N Kolonel, Satu Mannisto, Marjorie L McCullough, Marian L Neuhouser, Yikyung Park, et al.

Journal article  |  2016  |  International Journal of Cancer

RAD51B in Familial Breast Cancer

Liisa M Pelttari, Sofia Khan, Mikko Vuorela, Johanna I Kiiski, Sara Vilske, Viivi Nevanlinna, Salla Ranta, Johanna Schleutker, Robert Winqvist, Anne Kallioniemi, Thilo Doerk, Natalia V Bogdanova, Jonine Figueroa, Paul DP Pharoah, Marjanka K Schmidt, Alison M Dunning, Montserrat Garcia-Closas, Manjeet K Bolla, Joe Dennis, Kyriaki Michailidou, et al.

Journal article  |  2016  |  PLOS ONE

Genes associated with histopathologic features of triple negative breast tumors predict molecular subtypes

Kristen S Purrington, Daniel W Visscher, Chen Wang, Drakoulis Yannoukakos, Ute Hamann, Heli Nevanlinna, Angela Cox, Graham G Giles, Jeanette E Eckel-Passow, Sotiris Lakis, Vassiliki Kotoula, George Fountzilas, Maria Kabisch, Thomas Ruediger, Paivi Heikkila, Carl Blomqvist, Simon S Cross, Melissa C Southey, Janet E Olson, Judy Gilbert, et al.

Journal article  |  2016  |  Breast Cancer Research and Treatment

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry

Zhiguo Zhao, Wanqing Wen, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Ben Zhang, Jirong Long, Xiao-Ou Shu, Marjanka K Schmidt, Roger L Milne, Montserrat Garcia-Closas, Jenny Chang-Claude, Sara Lindstrom, Stig E Bojesen, Habibul Ahsan, Kristiina Aittomaki, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Matthias W Beckmann, et al.

Journal article  |  2016  |  Cancer Causes & Control

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing

Douglas F Easton, Fabienne Lesueur, Brennan Decker, Kyriaki Michailidou, Jun Li, Jamie Allen, Craig Luccarini, Karen A Pooley, Mitul Shah, Manjeet K Bolla, Qin Wang, Joe Dennis, Jamil Ahmad, Ella R Thompson, Francesca Damiola, Maroulio Pertesi, Catherine Voegele, Noura Mebirouk, Nivonirina Robinot, Geoffroy Durand, et al.

Journal article  |  2016  |  Journal of Medical Genetics

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

Antoinette Hollestelle, Frederieke H van der Baan, Andrew Berchuck, Sharon E Johnatty, Katja K Aben, Bjarni A Agnarsson, Kristiina Aittomaki, Elisa Alducci, Irene L Andrulis, Hoda Anton-Culver, Natalia N Antonenkova, Antonis C Antoniou, Carmel Apicella, Volker Arndt, Norbert Arnold, Banu K Arun, Brita Arver, Alan Ashworth, Laura Baglietto, Rosemary Balleine, et al.

Journal article  |  2016  |  Gynecologic Oncology

A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk

Ruth C Travis, Paul N Appleby, Richard M Martin, Jeff MP Holly, Demetrius Albanes, Amanda Black, H Bas Bueno-de-Mesquita, June M Chan, Chu Chen, Maria-Dolores Chirlaque, Michael B Cook, Melanie Deschasaux, Jenny L Donovan, Luigi Ferrucci, Pilar Galan, Graham G Giles, Edward L Giovannucci, Marc J Gunter, Laurel A Habel, Freddie C Hamdy, et al.

Journal article  |  2016  |  Cancer Research

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Mitchell J Machiela, Qing Lan, Susan L Slager, Roel CH Vermeulen, Lauren R Teras, Nicola J Camp, James R Cerhan, John J Spinelli, Sophia S Wang, Alexandra Nieters, Joseph Vijai, Meredith Yeager, Zhaoming Wang, Herve Ghesquieres, James Mckay, Lucia Conde, Paul IW de Bakker, David G Cox, Laurie Burdett, Alain Monnereau, et al.

Journal article  |  2016  |  Human Molecular Genetics

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders, Tokhir Dadaev, Daniel A Leongamornlert, Ali Amin Al Olama, Sara Benlloch, Graham G Giles, Fredrik Wiklund, Henrik Groenberg, Christopher A Haiman, Johanna Schleutker, Borge G Nordestgaard, Ruth C Travis, David Neal, Nora Pasayan, Kay-Tee Khaw, Janet L Stanford, William J Blot, Stephen N Thibodeau, Christiane Maier, Adam S Kibel, et al.

Journal article  |  2016  |  British Journal of Cancer

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

Carolina Bonilla, Sarah J Lewis, Richard M Martin, Jenny L Donovan, Freddie C Hamdy, David E Neal, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, Borge G Nordestgaard, Ruth C Travis, Nora Pashayan, et al.

Journal article  |  2016  |  BMC Medicine

Supervisor volume affects oncological outcomes of trainees performing open radical prostatectomy

Dermot O'Kane, Nathan Papa, Nathan Lawrentschuk, Rodney Syme, Graham Giles, Damien Bolton

Journal article  |  2016  |  ANZ Journal of Surgery

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Alexander Gusev, Huwenbo Shi, Gleb Kichaev, Mark Pomerantz, Fugen Li, Henry W Long, Sue A Ingles, Rick A Kittles, Sara S Strom, Benjamin A Rybicki, Barbara Nemesure, William B Isaacs, Wei Zheng, Curtis A Pettaway, Edward D Yeboah, Yao Tettey, Richard B Biritwum, Andrew A Adjei, Evelyn Tay, Ann Truelove, et al.

Journal article  |  2016  |  Nature Communications

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Fergus J Couch, Karoline B Kuchenbaecker, Kyriaki Michailidou, Gustavo A Mendoza-Fandino, Silje Nord, Janna Lilyquist, Curtis Olswold, Emily Hallberg, Simona Agata, Habibul Ahsan, Kristiina Aittomaeki, Christine Ambrosone, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Banu K Arun, Brita Arver, Monica Barile, Rosa B Barkardottir, Daniel Barrowdale, et al.

Journal article  |  2016  |  Nature Communications

Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals

Jonathan N Hofmann, Brenda M Birmann, Lauren R Teras, Ruth M Pfeiffer, Ye Wang, Demetrius Albanes, Dalsu Baris, Graham A Colditz, Anneclaire J De Roos, Graham G Giles, H Dean Hosgood, Qing Lan, Ola Landgren, Linda M Liao, Nathaniel Rothman, Stephanie J Weinstein, Michael N Pollak, Marian L Neuhouser, Mark P Purdue

Journal article  |  2016  |  Cancer Research

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

Alison M Dunning, Kyriaki Michailidou, Karoline B Kuchenbaecker, Deborah Thompson, Juliet D French, Jonathan Beesley, Catherine S Healey, Siddhartha Kar, Karen A Pooley, Elena Lopez-Knowles, Ed Dicks, Daniel Barrowdale, Nicholas A Sinnott-Armstrong, Richard C Sallari, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Mahdi Moradi Marjaneh, Jason S Lee, Margaret Hills, et al.

Journal article  |  2016  |  Nature Genetics

Determining the familial risk distribution of colorectal cancer: a data mining approach

Rowena Chau, Mark A Jenkins, Daniel D Buchanan, Driss Ait Ouakrim, Graham G Giles, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Aung Ko Win