Brian Chambers

Occlusive Disease and Upright Activity in Acute Ischemic Stroke

Lilian B Carvalho, Brian Chambers, Karen Borschmann, Tina Kaffenberger, Leonid Churilov, Vincent Thijs, Julie Bernhardt

Journal article  |  2021  |  JOURNAL OF STROKE & CEREBROVASCULAR DISEASES

The impact of out-of-bed upright activity on outcomes in ischemic stroke patients with severe extra- and intracranial stenosis or ..

Cerebral haemodynamics with head position changes post-ischaemic stroke: A systematic review and meta-analysis

Lilian B Carvalho, Sharon Kramer, Karen Borschmann, Brian Chambers, Vincent Thijs, Julie Bernhardt

Journal article  |  2020  |  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The effects of upright postures on the cerebral circulation early post-ischaemic stroke are not fully understood. We conducted a s..

Rates of age- and amyloid beta-associated cortical atrophy in older adults with superior memory performance

Christa Dang, Nawaf Yassi, Karra D Harrington, Ying Xia, Yen Ying Lim, David Ames, Simon M Laws, Martha Hickey, Stephanie Rainey-Smith, Hamid R Sohrabi, James D Doecke, Jurgen Fripp, Olivier Salvado, Peter J Snyder, Michael Weinborn, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article  |  2019  |  ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING

INTRODUCTION: Superior cognitive performance in older adults may reflect underlying resistance to age-associated neurodegeneration..

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection

Anne L Abbott, Julia Merican, Dora C Pearce, Ana Juric, Christopher Worsnop, Emma Foster, Brian Chambers

Journal article  |  2019  |  FRONTIERS IN NEUROLOGY

Background and Purpose: Variability in transcranial Doppler (TCD) detection of embolic signals (ES) is important for risk stratifi..

Persistently Elevated Microvascular Resistance Postrecanalization A Clinical Marker of No-Reflow Phenomenon

Felix C Ng, Bronwyn Coulton, Brian Chambers, Vincent Thijs

Journal article  |  2018  |  STROKE

Background and Purpose- Impaired microvascular reperfusion despite complete recanalization (no-reflow) represents a potential ther..

Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial

Leo H Bonati, John Gregson, Joanna Dobson, Dominick JH McCabe, Paul J Nederkoorn, H Bart van der Worp, Gert J de Borst, Toby Richards, Trevor Cleveland, Mandy D Mueller, Thomas Wolff, Stefan T Engelter, Philippe A Lyrer, Martin M Brown

Journal article  |  2018  |  LANCET NEUROLOGY

BACKGROUND: The risk of stroke associated with carotid artery restenosis after stenting or endarterectomy is unclear. We aimed to ..

Does left ventricular hypertrophy affect cognition and brain structural integrity in type 2 diabetes? Study design and rationale of the Diabetes and Dementia (D2) study

Sheila K Patel, Carolina Restrepo, Emilio Werden, Leonid Churilov, Elif I Ekinci, Piyush M Srivastava, Jay Ramchand, Bryan Wai, Brian Chambers, Christopher J O'Callaghan, David Darby, Vladimir Hachinski, Toby Cumming, Geoff Donnan, Louise M Burrell, Amy Brodtmann

Journal article  |  2017  |  BMC ENDOCRINE DISORDERS

BACKGROUND: Cognitive impairment is common in type 2 diabetes mellitus, and there is a strong association between type 2 diabetes ..

Antiplatelet therapy following ischaemic stroke - Continue or change pre-existing therapy?

Wardati Mazlan-Kepli, Rachael L MacIsaac, Matthew Walters, Philip MW Bath, Jesse Dawson

Journal article  |  2017  |  EUROPEAN STROKE JOURNAL

INTRODUCTION: Antiplatelet therapy is routinely prescribed early after ischaemic stroke. Many patients will already be taking anti..

Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE epsilon 4 and Is Detectable over 18-Months

Christine Thai, Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Kathryn A Ellis, Stephanie R Rainey-Smith, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruff

Journal article  |  2015  |  PLOS ONE

High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cog..

No Relationship of Lipid-Lowering Agents to Hematoma Growth Pooled Analysis of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials Studies

Miriam Priglinger, Hisatomi Arima, Craig Anderson, Martin Krause

Journal article  |  2015  |  STROKE

BACKGROUND AND PURPOSE: Controversy persists over statins and risk of intracerebral hemorrhage. We determined associations of prem..