David Power

The importance of the Heart Team evaluation before transcatheter aortic valve replacement: Results from the BRAVO-3 trial

Anton Camaj, Bimmer E Claessen, Roxana Mehran, Matias B Yudi, David Power, Usman Baber, Christian Hengstenberg, Thierry Lefevre, Eric Van Belle, Gennaro Giustino, Paul Guedeney, Sabato Sorrentino, Christian Kupatt, John G Webb, David Hildick-Smith, Hans U Hink, Efthymios N Deliargyris, Prodromos Anthopoulos, Samin K Sharma, Annapoorna Kini, et al.

Journal article  |  2020  |  Catheterization and Cardiovascular Interventions

BACKGROUND/OBJECTIVES: Clinicians use validated scores to risk-stratify patients undergoing transcatheter aortic valve replacement..

Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility

Sih Min Tan, Mark Ziemann, Vicki Thallas-Bonke, Matthew Snelson, Vinod Kumar, Adrienne Laskowski, Tuong-Vi Nguyen, Kevin Huynh, Michele V Clarke, Renata Libianto, Scott T Baker, Alison Skene, David A Power, Richard J MacIsaac, Darren C Henstridge, Rick A Wetsel, Assam El-Osta, Peter J Meikle, Scott G Wilson, Josephine M Forbes, et al.

Journal article  |  2020  |  Diabetes

The sequelae of diabetes mellitus include microvascular complications such as diabetic kidney disease (DKD), which involves glucos..

Diabetes and higher HbA1c levels are independently associated with adverse renal outcomes in inpatients following multiple hospital admissions

N Torkamani, L Churilov, R Robbins, G Jerums, V Beik, N Radcliffe, S Patterson, R Bellomo, J Burns, GK Hart, Q Lam, DA Power, RJ MacIsaac, DF Johnson, J Zajac, E Ekinci

Journal article  |  2020  |  Journal of Diabetes and its Complications

OBJECTIVE: To assess the association between glycaemic status prior to the first hospital presentation with developing adverse ren..

Costs and outcomes of advance care planning and end-of-life care for older adults with end-stage kidney disease: A person-centred decision analysis

Marcus Sellars, Josephine M Clayton, Karen M Detering, Allison Tong, David Power, Rachael L Morton

Journal article  |  2019  |  PLOS ONE

Diagnostic application of kidney allograft-derived absolute cell-free DNA levels during transplant dysfunction

John B Whitlam, Ling Ling, Alison Skene, John Kanellis, Francseco L Ierino, Howard R Slater, Damien L Bruno, David A Power

Journal article  |  2019  |  American Journal of Transplantation

Absence of the beta 1 subunit of AMP-activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes

Suet-Wan Choy, Scott A Fraser, Marina Katerelos, Sandra Galic, Bruce E Kemp, Peter F Mount, David A Power

Journal article  |  2019  |  International Journal of Experimental Pathology

Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia

R Ellis, M Katerelos, SW Choy, N Cook, M Lee, K Paizis, G Pell, S Walker, DA Power, PF Mount

Journal article  |  2019  |  Journal of Translational Medicine

Three Dimensional Glomerular Reconstruction: A Novel Approach to Evaluate Renal Microanatomy in Diabetic Kidney Disease

Niloufar Torkamani, George Jerums, Paul Crammer, Alison Skene, David A Power, Sianna Panagiotopoulos, Michele Clarke, Richard J MacIsaac, Elif I Ekinci

Journal article  |  2019  |  Scientific Reports

Case-control study of end-of-life treatment preferences and costs following advance care planning for adults with end-stage kidney disease

Marcus Sellars, Rachael L Morton, Josephine M Clayton, Allison Tong, Daveena Mawren, William Silvester, David Power, Ronald Ma, Karen M Detering

Journal article  |  2019  |  Nephrology

Pre-eclampsia is associated with altered expression of the renal sodium transporters NKCC2, NCC and ENaC in urinary extracellular vesicles

Chih-Chiang Hu, Marina Katerelos, Suet-Wan Choy, Amy Crossthwaite, Susan P Walker, Gabrielle Pell, Mardiana Lee, Natasha Cook, Peter F Mount, Kathy Paizis, David A Power

Journal article  |  2018  |  PLOS ONE

Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin

Mardiana Lee, Marina Katerelos, Kurt Gleich, Sandra Galic, Bruce E Kemp, Peter F Mount, David A Power

Journal article  |  2018  |  Journal of the American Society of Nephrology

Malignant Hypertension Causing a Pulmonary-Renal Syndrome.

Bryan Yong, David A Power

Journal article  |  2018  |  Case Reports in Nephrology

Background: Pulmonary-renal syndrome is characterised by acute kidney injury, haematuria, and haemoptysis and is a well-recognised..

NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy

Jay C Jha, Claudine Banal, Jun Okabe, Stephen P Gray, Thushan Hettige, Bryna SM Chow, Vicki Thallas-Bonke, Lisanne De Vos, Chet E Holterman, Melinda T Coughlan, David A Power, Alison Skene, Elif I Ekinci, Mark E Cooper, Rhian M Touyz, Chris R Kennedy, Karin Jandeleit-Dahm

Journal article  |  2017  |  Diabetes

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

Joshua D Ooi, Jan Petersen, Yu H Tan, Megan Huynh, Zoe J Willett, Sri H Ramarathinam, Peter J Eggenhuizen, Khai L Loh, Katherine A Watson, Poh Y Gan, Maliha AA Likhan, Nadine L Dudek, Andreas Handel, Billy G Hudson, Lars Fugger, David A Power, Stephen G Holt, P Toby Coates, Jon W Gregersen, Anthony W Purcell, et al.

Journal article  |  2017  |  Nature

INTRODUCTION OF RENAL KEY PERFORMANCE INDICATORS ASSOCIATED WITH INCREASED UPTAKE OF PERITONEAL DIALYSIS IN A PUBLICLY FUNDED HEALTH SERVICE

Nigel D Toussaint, Lawrence P McMahon, Gregory Dowling, Stephen G Holt, Gillian Smith, Maria Safe, Richard Knight, Kathleen Fair, Leanne Linehan, Rowan G Walker, David A Power

Journal article  |  2017  |  Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis

Melinda T Coughlan, Gavin C Higgins, Nguyen Tuong-Vi, Sally A Penfold, Vicki Thallas-Bonke, Sih Mm Tan, Georg Ramm, Nicole J Van Bergen, Darren C Henstridge, Karly C Sourris, Brooke E Harcourt, Ian A Trounce, Portia M Robb, Adrienne Laskowski, Sean L McGee, Amanda J Genders, Ken Walder, Brian G Drew, Paul Gregorevic, Hongwei Qian, et al.

Journal article  |  2016  |  Diabetes

Deficiency in Apoptosis Inducing Factor Recapitulates Diabetic Nephropathy via Aberrant Mitochondrial Homeostasis

Melinda T Coughlan, Gavin C Higgins, Tuong-Vi Nguyen, Sally A Penfold, Vicki Thallas-Bonke, Sih Min Tan, Georg Ramm, Nicole J Van Bergen, Darren C Henstridge, Ian A Trounce, Karly C Sourris, Brooke E Harcourt, Portia M Robb, Adrienne Laskowski, Sean L Mcgee, Ken Walder, Paul Gregorevic, Hongwei Qian, Merlin C Thomas, Brian G Drew, et al.

Conference Proceedings  |  2015  |  DIABETES

The Thiazide-Sensitive Co-Transporter Promotes the Development of Sodium Retention in Mice with Diet-Induced Obesity

Matthew RP Davies, Kurt Gleich, Marina Katerelos, Mardiana Lee, Peter F Mount, David A Power

Journal article  |  2015  |  Kidney and Blood Pressure Research

Novel mechanisms of Na retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK

Matthew Davies, Scott A Fraser, Sandra Galic, Suet-Wan Choy, Marina Katerelos, Kurt Gleich, Bruce E Kemp, Peter F Mount, David A Power

Journal article  |  2014  |  American Journal of Physiology: Renal Physiology

Absence of the lysosomal protein Limp-2 attenuates renal injury in crescentic glomerulonephritis

Darren Hiu Kwong Lee, Poh-Yi Gan, Marina Katerelos, Scott Andrew Fraser, Kurt Gleich, Stephen Roger Holdsworth, David Anthony Power

Journal article  |  2014  |  Immunology and Cell Biology

AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patients

Kevin J Martin, Karen Pickthorn, Saling Huang, Geoffrey A Block, Andrew Vick, Peter F Mount, David A Power, Gregory Bell

Journal article  |  2014  |  Kidney International

Renal Structure in Normoalbuminuric and Albuminuric Patients With Type 2 Diabetes and Impaired Renal Function

Elif I Ekinci, George Jerums, Alison Skene, Paul Crammer, David Power, Karey Y Cheong, Sianna Panagiotopoulos, Karen McNeil, Scott T Baker, Paola Fioretto, Richard J MacIsaac

Journal article  |  2013  |  DIABETES CARE

AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1

Scott A Fraser, Suet-Wan Choy, Nuria M Pastor-Soler, Hui Li, Matthew RP Davies, Natasha Cook, Marina Katerelos, Peter F Mount, Kurt Gleich, Jennifer L McRae, Karen M Dwyer, Bryce JW van Denderen, Kenneth R Hallows, Bruce E Kemp, David A Power

Journal article  |  2013  |  American Journal of Physiology: Renal Physiology

Limited capacity of proximal tubular proteolysis in mice with proteinuria

D Lee, K Gleich, SA Fraser, M Katerelos, PF Mount, DA Power

Journal article  |  2013  |  American Journal of Physiology: Renal Physiology

Abnormal Processing of Autophagosomes in Transformed B Lymphocytes from SCARB2-Deficient Subjects.

Kurt Gleich, Michael J Desmond, Darren Lee, Samuel F Berkovic, Leanne M Dibbens, Marina Katerelos, Marta A Bayly, Scott A Fraser, Paul Martinello, Danya F Vears, Peter Mount, David A Power

Journal article  |  2013  |  BioResearch Open Access

Mutations of the intrinsic lysosomal membrane protein SCARB2 cause action myoclonus-renal failure syndrome (AMRF syndrome), a rare..

The Outcome of Renal Ischemia-Reperfusion Injury Is Unchanged in AMPK-beta 1 Deficient Mice

Peter F Mount, Kurt Gleich, Shanna Tam, Scott A Fraser, Suet-Wan Choy, Karen M Dwyer, Bo Lu, Bryce Van denderen, Guenter Fingerle-Rowson, Richard Bucala, Bruce E Kemp, David A Power

Journal article  |  2012  |  PLoS One

Expression of the Transmembrane Lysosomal Protein SCARB2/Limp-2 in Renin Secretory Granules Controls Renin Release

D Lee, MJ Desmond, SA Fraser, M Katerelos, K Gleich, SF Berkovic, DA Power

Journal article  |  2012  |  Nephron Experimental Nephrology

Vision-Threatening Retinal Abnormalities in Chronic Kidney Disease Stages 3 to 5

Rajeev Deva, Mohamad Afzal Alias, Deb Colville, Foong Kien Newk-Fon Hey Tow, Qi Lun Ooi, Sky Chew, Nor Mohamad, Anastasia Hutchinson, Ignatios Koukouras, David A Power, Judith Savige

Journal article  |  2011  |  Clinical Journal of the American Society of Nephrology

Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2

MJ Desmond, D Lee, SA Fraser, M Katerelos, K Gleich, P Martinello, YQ Li, MC Thomas, R Michelucci, AJ Cole, P Saftig, M Schwake, D Stapleton, SF Berkovic, DA Power

Journal article  |  2011  |  American Journal of Physiology: Renal Physiology

5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-kappa B

Marina Katerelos, Stuart J Mudge, David Stapleton, Russell B Auwardt, Scott A Fraser, C-G Chen, Bruce E Kemp, David A Power

Journal article  |  2010  |  Immunology and Cell Biology

SCARB2 Mutations in Progressive Myoclonus Epilepsy (PME) Without Renal Failure

LM Dibbens, R Michelucci, A Gambardella, F Andermann, G Rubboli, MA Bayly, T Joensuu, DF Vears, S Franceschetti, L Canafoglia, R Wallace, AG Bassuk, DA Power, CA Tassinari, E Andermann, AE Lehesjoki, SF Berkovic

Journal article  |  2009  |  Annals of Neurology

Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells

Natasha Cook, Scott A Fraser, Marina Katerelos, Frosa Katsis, Kurt Gleich, Peter F Mount, Gregory R Steinberg, Vicki Levidiotis, Bruce E Kemp, David A Power

Journal article  |  2009  |  American Journal of Physiology: Renal Physiology

New and old markers of progression of diabetic nephropathy

G Jerums, E Premaratne, S Panagiotopoulos, S Clarke, DA Power, RJ MacIsaac

Journal article  |  2008  |  Diabetes Research and Clinical Practice

Lowering of Proteinuria in Response to Antihypertensive Therapy Predicts Improved Renal Function in Late but Not in Early Diabetic Nephropathy: A Pooled Analysis

George Jerums, Sianna Panagiotopoulos, Erosha Premaratne, David A Power, Richard J MacIsaac

Journal article  |  2008  |  American Journal of Nephrology

Predictors of early dialysis vascular-access failure after thrombolysis

Sandra Crikis, Darren Lee, Mark Brooks, David A Power, Francesco L Ierino, Vicki Levidiotis

Journal article  |  2008  |  American Journal of Nephrology

Low molecular weight advanced glycation end products predict mortality in asymptomatic patients receiving chronic haemodialysis

Matthew A Roberts, Merlin C Thomas, Dharsh Fernando, Neil Macmillan, David A Power, Francesco L Ierino

Journal article  |  2006  |  Nephrology, Dialysis, Transplantation

Phosphorylation of neuronal and endothelial nitric oxide synthase in the kidney with high and low salt diets

Peter F Mount, Scott A Fraser, Yasuo Watanabe, Natalie Lane, Frosa Katsis, Zhi-Ping Chen, Bruce E Kemp, David A Power

Journal article  |  2006  |  Nephron Experimental Nephrology

Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser(1177)

PF Mount, RE Hill, SA Fraser, V Levidiotis, F Katsis, BE Kemp, DA Power

Journal article  |  2005  |  American Journal of Physiology: Renal Physiology

The risks of thin basement membrane nephropathy

S Tonna, YY Wang, D MacGregor, R Sinclair, P Martinello, D Power, J Savige

Journal article  |  2005  |  Seminars in Nephrology

Heparanase inhibition reduces proteinuria in a model of accelerated anti-glomerular basement membrane antibody disease

V Levidiotis, C Freeman, C Tikellis, ME Cooper, DA Power

Journal article  |  2005  |  Nephrology

New insights into the molecular biology of the glomerular filtration barrier and associated disease

V Levidiotis, DA Power

Journal article  |  2005  |  Nephrology

Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality

Scott Fraser, Peter Mount, Rebecca Hill, Vicki Levidiotis, Frosa Katsis, David Stapleton, Bruce E Kemp, David A Power

Journal article  |  2005  |  American Journal of Physiology: Renal Physiology

The AMP-activated protein kinase (AMPK) is a key controller of cellular energy metabolism. We studied its expression and regulatio..

A study of VEGF and its receptors in two rat models of proteinuria.

John Kanellis, Vicki Levidiotis, Tiffany Khong, Alison J Cox, Steven A Stacker, Richard E Gilbert, Mark E Cooper, David A Power

Journal article  |  2004  |  Nephron

BACKGROUND: The high level of expression of vascular endothelial growth factor (VEGF) in normal podocyte foot processes suggests t..

Single and serial measurements of cardiac troponin I in asymptomatic patients on chronic hemodialysis

MA Roberts, D Fernando, N Macmillan, G Proimos, LA Bach, DA Power, S Ratnaike, FL Ierino

Journal article  |  2004  |  Clinical Nephrology

Renal ischemia-reperfusion increases endothelial VEGFR-2 without increasing VEGF or VEGFR-1 expression

J Kanellis, K Paizis, AJ Cox, SA Stacker, RE Gilbert, ME Cooper, DA Power

Journal article  |  2002  |  Kidney International

Increased expression of heparanase in puromycin aminonucleoside nephrosis

V Levidiotis, J Kanellis, FL Ierino, DA Power

Journal article  |  2001  |  Kidney International