Robin Gasser

Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold

Chen Zhang, Kah Yean Lum, Aya C Taki, Robin B Gasser, Joseph J Byrne, Tao Wang, Mark AT Blaskovich, Emery T Register, Luis J Montaner, Ian Tietjen, Rohan A Davis

Journal article  |  2021  |  PHYTOCHEMISTRY

Chemical studies of the aerial parts of the Australian desert plant Eremophila microtheca afforded the targeted and known diterpen..

Harnessing model organism genomics to underpin the machine learning-based prediction of essential genes in eukaryotes - Biotechnological implications.

Tulio L Campos, Pasi K Korhonen, Andreas Hofmann, Robin B Gasser, Neil D Young

Journal article  |  2021  |  Biotechnol Adv

The availability of high-quality genomes and advances in functional genomics have enabled large-scale studies of essential genes i..

Detection of Breinlia sp. (Nematoda) in the Leadbeater's possum (Gymnobelideus leadbeateri)

Chloe Steventon, Anson V Koehler, Elizabeth Dobson, Leanne Wicker, Alistair R Legione, Joanne M Devlin, Dan Harley, Robin B Gasser

Journal article  |  2021  |  INTERNATIONAL JOURNAL FOR PARASITOLOGY-PARASITES AND WILDLIFE

The Leadbeater's possum (Gymnobelideus leadbeateri) is a critically endangered marsupial in south-eastern Australia. Among other c..

How qPCR complements the WHO roadmap (2021-2030) for soil-transmitted helminths

Marina Papaiakovou, Timothy J Littlewood, Robin B Gasser, Roy M Anderson

Journal article  |  2021  |  TRENDS IN PARASITOLOGY

Complementing the launch of the World Health Organization (WHO) roadmap (2021-2030) we explore key elements needing attention befo..

Phytochemical Profiling and Biological Activity of the Australian Carnivorous Plant, Drosera magna (vol 84, pg 964, 2021)

Edward Owen Norman, Hayden Tuohey, David Pizzi, Milane Saidah, Rachael Bell, Robert Brkljaca, Jonathan M White, Robin B Gasser, Aya C Taki, Sylvia Urban

Journal article  |  2021  |  JOURNAL OF NATURAL PRODUCTS

With respect to the structures of compounds10-12, an error was noted. The compounds were incorrectly presented as 2,3-dihydro-1,4-..

First Evidence of Function for Schistosoma japonicum riok-1 and RIOK-1

Mudassar N Mughal, Qing Ye, Lu Zhao, Christoph G Grevelding, Ying Li, Wenda Di, Xin He, Xuesong Li, Robin B Gasser, Min Hu

Journal article  |  2021  |  PATHOGENS

Protein kinases are known as key molecules that regulate many biological processes in animals. The right open reading frame protei..

Practical High-Throughput Method to Screen Compounds for Anthelmintic Activity against Caenorhabditis elegans

Aya C Taki, Joseph J Byrne, Peter R Boag, Abdul Jabbar, Robin B Gasser

Journal article  |  2021  |  MOLECULES

In the present study, we established a practical and cost-effective high throughput screening assay, which relies on the measureme..

High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus

Aya C Taki, Joseph J Byrne, Tao Wang, Brad E Sleebs, Nghi Nguyen, Ross S Hall, Pasi K Korhonen, Bill CH Chang, Paul Jackson, Abdul Jabbar, Robin B Gasser

Journal article  |  2021  |  PHARMACEUTICALS

Parasitic worms cause very significant diseases in animals and humans worldwide, and their control is critical to enhance health, ..

Prospects of Using High-Throughput Proteomics to Underpin the Discovery of Animal Host-Nematode Interactions

Tao Wang, Robin B Gasser

Journal article  |  2021  |  PATHOGENS

Parasitic nematodes impose a significant public health burden, and cause major economic losses to agriculture worldwide. Due to th..

Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro

Aya C Taki, Abdul Jabbar, Thomas Kurz, Beate Lungerich, Guangxu Ma, Joseph J Byrne, Marc Pflieger, Yodita Asfaha, Fabian Fischer, Bill CH Chang, Brad E Sleebs, Robin B Gasser

Journal article  |  2021  |  MOLECULES

Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthe..