Andrea O'Connor

Using inorganic nanoparticles to fight fungal infections in the antimicrobial resistant era.

Tao Huang, Xin Li, Michael Maier, Neil M O'Brien-Simpson, Daniel E Heath, Andrea J O'Connor

Journal article  |  2023  |  Acta Biomater

Fungal infections pose a serious threat to human health and livelihoods. The number and variety of clinically approved antifungal ..

Improvement of Mesenchymal Stromal Cell Proliferation and Differentiation via Decellularized Extracellular Matrix on Substrates With a Range of Surface Chemistries.

Michael C Yang, Andrea J O'Connor, Bill Kalionis, Daniel E Heath

Journal article  |  2022  |  Front Med Technol

Decellularized extracellular matrix (dECM) deposited by mesenchymal stromal cells (MSCs) has emerged as a promising substrate for ..

The Potential of Calcium Phosphate Nanoparticles as Adjuvants and Vaccine Delivery Vehicles

Zhe Sun, Wenyi Li, Jason C Lenzo, James A Holden, Michael J McCullough, Andrea J O'Connor, Neil M O'Brien-Simpson

Journal article  |  2021  |  FRONTIERS IN MATERIALS

Vaccination is one of the most efficacious and cost-effective ways to protect people from infectious diseases and potentially canc..

A review of simulation training and new 3D computer-generated synthetic organs for robotic surgery education

Daniel M Costello, Isabel Huntington, Grace Burke, Brooke Farrugia, Andrea J O'Connor, Anthony J Costello, Benjamin C Thomas, Philip Dundee, Ahmed Ghazi, Niall Corcoran

Journal article  |  2021  |  JOURNAL OF ROBOTIC SURGERY

We conducted a comprehensive review of surgical simulation models used in robotic surgery education. We present an assessment of t..

Amphiphilic Core Cross-Linked Star Polymers for the Delivery of Hydrophilic Drugs from Hydrophobic Matrices

Katarzyna Somszor, Stephanie Allison-Logan, Fatemeh Karimi, Thomas McKenzie, Qiang Fu, Andrea O'Connor, Greg Qiao, Daniel Heath

Journal article  |  2021  |  BIOMACROMOLECULES

The delivery of hydrophilic drugs from hydrophobic polymers is a long-standing challenge in the biomaterials field due to the limi..

The Challenge of Cartilage Integration: Understanding a Major Barrier to Chondral Repair

Anna Trengove, Claudia Di Bella, Andrea J O'Connor

Journal article  |  2021  |  TISSUE ENGINEERING PART B-REVIEWS

Articular cartilage defects caused by injury frequently lead to osteoarthritis, a painful and costly disease. Despite widely used ..

Microbial Transglutaminase Improves ex vivo Adhesion of Gelatin Methacryloyl Hydrogels to Human Cartilage.

Anna Trengove, Serena Duchi, Carmine Onofrillo, Cathal D O'Connell, Claudia Di Bella, Andrea J O'Connor

Journal article  |  2021  |  Front Med Technol

Current surgical techniques to treat articular cartilage defects fail to produce a satisfactory long-term repair of the tissue. Re..

Multifunctional Antimicrobial Polypeptide-Selenium Nanoparticles Combat Drug-Resistant Bacteria

Tao Huang, James A Holden, Eric C Reynolds, Daniel E Heath, Neil M O'Brien-Simpson, Andrea J O'Connor

Journal article  |  2020  |  ACS APPLIED MATERIALS & INTERFACES

Antibiotic-resistant bacteria are a severe threat to human health. The World Health Organization's Global Antimicrobial Surveillan..

Personalized, Mechanically Strong, and Biodegradable Coronary Artery Stents via Melt Electrowriting

Katarzyna Somszor, Onur Bas, Fatemeh Karimi, Tara Shabab, Navid T Saidy, Andrea J O'Connor, Amanda Ellis, Dietmar Hutmacher, Daniel E Heath

Journal article  |  2020  |  ACS MACRO LETTERS

Biodegradable coronary artery stents are sought-after alternatives to permanent stents. These devices are designed to degrade afte..

Effects of External Stimulators on Engineered Skeletal Muscle Tissue Maturation

Claudia Mueller, Mairon Trujillo-Miranda, Michael Maier, Daniel E Heath, Andrea J O'Connor, Sahar Salehi

Journal article  |  2020  |  ADVANCED MATERIALS INTERFACES

Engineering functional skeletal muscle tissue is an ongoing challenge because of the complexity of the in vivo microenvironment an..