Professor Andrea O’Connor, BE(Hons), PhD, FIChemE is the Head of the Department of Biomedical Engineering and leads the Tissue Engineering Group at the University of Melbourne. She was a Fulbright Scholar at Massachusetts Institute of Technology in 1995-96.
Her research is focussed on design, synthesis and fabrication of biomaterials, porous materials and antimicrobial nanomaterials. She is particularly interested in strategies for scale-up of tissue engineering including vascularisation, and design of antimicrobial materials for medical implants. She has published over 80 journal articles, co-authored the chapter on Tissue Engineering for the major reference work ‘Plastic Surgery’ edited by Neligan and Gurtner, lectured on tissue engineering and biofabrication at the Bayreuth International Summer School, Germany, and was a finalist in the 2017 Graeme Clark Institute HealthTech Innovation Challenge. Andrea also led the engineering team on the world-first Neopec clinical trial of breast reconstruction using tissue engineering, showing proof-of-principle of tissue engineering of large volumes of well vascularised fat tissue. She collaborates with a range of hospitals, medical research institutes and medical device companies to improve existing products, develop new devices and solve clinical problems.
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Andrea O'Connor's selected work
Spider-silk inspired polymeric networks by harnessing the mechanical potential of β-sheets..
Advanced Materials For The Manufacturing And Delivery Of Highly Potent Mesenchymal Stem Ce..
Displaying the 39 most recent projects by Andrea O'Connor.
Internal Research Grant
Displaying the 121 most recent scholarly works by Andrea O'Connor.
Spider-silk inspired polymeric networks by harnessing the mechanical potential of β-sheets through network guided assembly.
Nicholas Jun-An Chan, Dunyin Gu, Shereen Tan, Qiang Fu, Thomas Geoffrey Pattison, Andrea J O'Connor, Greg G Qiao
Journal article | 2020 | Nature Communications
The high toughness of natural spider-silk is attributed to their unique β-sheet secondary structures. However, the preparation of ..
Development of Macroporous Chitosan Scaffolds for Eyelid Tarsus Tissue Engineering
Michelle T Sun, Andrea J O’Connor, Imogen Milne, Dhee Biswas, Robert Casson, John Wood, Dinesh Selva
Journal article | 2019 | Tissue Engineering and Regenerative Medicine
Background: Reconstruction of large eyelid defects remains challenging due to the lack of suitable eyelid tarsus tissue substitute..
Continuous production of hierarchically porous silica beads using co-axial flow
Stephan Burger, Alex Lubansky, Andrea J O'Connor
Journal article | 2019 | Microporous and Mesoporous Materials
Applications of porous materials require macroscopic shapes, which makes it easier to handle and recover them. The direct fabricat..
Biocompatible and Biodegradable Magnesium Oxide Nanoparticles with In Vitro Photostable Near-Infrared Emission: Short-Term Fluorescent Markers
Asma Khalid, Romina Norello, Amanda N Abraham, Jean-Philippe Tetienne, Timothy J Karle, Edward WC Lui, Kenong Xia, Phong A Tran, Andrea J O'Connor, Bruce G Mann, Richard de Boer, Yanling He, Alan Man Ching Ng, Aleksandra B Djurisic, Ravi Shukla, Snjezana Tomljenovic-Hanic
Journal article | 2019 | Nanomaterials
Imaging of biological matter by using fluorescent nanoparticles (NPs) is becoming a widespread method for in vitro imaging. Howeve..
Engineering highly effective antimicrobial selenium nanoparticles through control of particle size
Tao Huang, James A Holden, Daniel E Heath, Neil M O'Brien-Simpson, Andrea J O'Connor
Journal article | 2019 | Nanoscale
The overuse of antibiotics has induced the rapid development of antibiotic resistance in bacteria. As a result, antibiotic efficac..
Selenium nanoparticles as anti-infective implant coatings for trauma orthopedics against methicillin-resistant Staphylococcus aureus and epidermidis: in vitro and in vivo assessment
Phong Atran, Neil O'Brien-Simpson, Jason A Palmer, Nathalie Bock, Eric C Reynolds, Thomas J Webster, Anand Deva, Wayne A Morrison, Andrea J O'Connor
Journal article | 2019 | International Journal of Nanomedicine
Background: Bacterial infection is a common and serious complication in orthopedic implants following traumatic injury, which is o..
Evaluation of sterilisation methods for bio-ink components: gelatin, gelatin methacryloyl, hyaluronic acid and hyaluronic acid methacryloyl
Cathal D O'Connell, Carmine Onofrillo, Serena Duchi, Xin Li, Yifan Zhang, Peilin Tian, Lanyita Lu, Anna Trengove, Anita Quigley, Sanjeev Gambhir, Afsaneh Khansari, Tajanka Mladenovska, Andrea O'Connor, Claudia Di Bella, Peter F Choong, Gordon G Wallace
Journal article | 2019 | Biofabrication
Reliable and scalable sterilisation of hydrogels is critical to the clinical translation of many biofabrication approaches, such a..
Synthesis of ultra small nanoparticles (< 50 nm) of mesoporous MCM-48 for bio-adsorption
SM Mousavi Elyerdi, MN Sarvi, AJ O’Connor
Journal article | 2019 | Journal of Porous Materials
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Mono-dispersed spherical MCM-48 mesoporous silica nanoparti..
Integrin Clustering Matters: A Review of Biomaterials Functionalized with Multivalent Integrin-Binding Ligands to Improve Cell Adhesion, Migration, Differentiation, Angiogenesis, and Biomedical Device Integration
Fatemeh Karimi, Andrea J O'Connor, Greg G Qiao, Daniel E Heath
Journal article | 2018 | Advanced Healthcare Materials
Interaction of preservation methods and radiation sterilization in human skin processing, with particular insight on the impact of the final water content and collagen disruption. Part I: process validation, water activity and collagen changes in tissues cryopreserved or processed using 50, 85 or 98% glycerol solutions
MR Herson, K Hamilton, J White, D Alexander, S Poniatowski, AJ O'Connor, JA Werkmeister
Journal article | 2018 | Cell and Tissue Banking
Transferable Matrixes Produced from Decellularized Extracellular Matrix Promote Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells and Facilitate Scale-Up
Gina D Kusuma, Michael C Yang, Shaun P Brennecke, Andrea J O'Connor, Bill Kalionis, Daniel E Heath
Journal article | 2018 | ACS Biomaterials Science & Engineering
Comparative study of novel in situ decorated porous chitosan-selenium scaffolds and porous chitosan-silver scaffolds towards antimicrobial wound dressing application
Dhee P Biswas, Neil M O'Brien-Simpson, Eric C Reynolds, Andrea J O'Connor, Phong A Tran
Journal article | 2018 | Journal of Colloid and Interface Science
Nano-scale clustering of integrin-binding ligands regulates endothelial cell adhesion, migration, and endothelialization rate: novel materials for small diameter vascular graft applications
Fatemeh Karimi, Thomas G McKenzie, Andrea J O'Connor, Greg G Qiao, Daniel E Heath
Journal article | 2017 | Journal of Materials Chemistry B
Long-Term Stability of Adipose Tissue Generated from a Vascularized Pedicled Fat Flap inside a Chamber
Juergan H Doldere, Erik W Thompson, John Slavin, Nicholas Trost, Justin J Cooper-White, Yang Cao, Andrea J O'Connor, Anthony Penington, Wayne A Morrison, Keren M Abberton
Journal article | 2011 | Plastic and Reconstructive Surgery
A comparison between ceramic and polymeric membrane systems for casein concentrate manufacture
Kensuke Karasu, Nicole Glennon, Nicole D Lawrence, Geoffrey W Stevens, Andrea J O'Connor, Andrew R Barber, Shiro Yoshikawa, Sandra E Kentish
Journal article | 2010 | International Journal of Dairy Technology
The influence of architecture on degradation and tissue ingrowth into three-dimensional poly(lactic-co-glycolic acid) scaffolds in vitro and in vivo
Y Cao, G Mitchell, A Messina, L Price, E Thompson, A Penington, W Morrison, A O'Connor, G Stevens, J Cooper-White
Journal article | 2006 | Biomaterials
Systematic selection of solvents for the fabrication of 3D combined macro- and microporous polymeric scaffolds for soft tissue engineering
Yang Cao, Tristan I Croll, Andrea J O'Connor, Geoffrey W Stevens, Justin J Cooper-White
Journal article | 2006 | Journal of Biomaterials Science. Polymer Edition
Microemulsion templated mesoporous silica: characterisation via small angle x-ray scattering and stability in aqueous buffers
S Boskovic, CF Maitland, J Connolly, CE Buckley, TW Turney, ML Gee, GW Stevens, AJ O'Connor
Conference Proceedings | 2005 | Nanoporous Materials IV, Proceedings of the 4th International Symposium on Nanoporous Materials, Niagra Falls, Canada
Increasing the Volume of Vascularized Tissue Formation in Engineered Constructs: An Experimental Study in Rats
Stefan OP Hofer, Katherine M Knight, Justin J Cooper-White, Andrea J O'Connor, Jilska M Perera, Rosalind Romeo-Meeuw, Anthony J Penington, Kenneth R Knight, Wayne A Morrison, Aurora Messina
Journal article | 2003 | Plastic and Reconstructive Surgery
Soft Tissue Engineering for Organ Replacement: Design and Manufacture of 3D Biomimetic, Biodegradable Polymer Scaffolds
J COOPER-WHITE, Y CAO, TI CROLL, A O'CONNOR, G QIAO, G STEVENS
Conference Proceedings | 2003 | CHEMECA 2003 The 31st Australasia Chemical Engineering Conference, Products and Processes for the 21st Century
Displaying the 3 most recent news articles by Andrea O'Connor.
Honours, Awards and Fellowships
Best Paper Award for 2007
Selby Research Award
Science and Technology Agency of Japan Fellowship
Fullbright Occasional Lecturer Award
Fulbright Postdoctoral Fellow Award - Massachusetts Institute of Technology
Postgraduate Scholarship 3 years
Scholarship 3 years
FICHEME - Fellow of the Institution of Chemical Engineers
Head Of Biomedical Engineering
Associate Editor, Journal Of Biomaterials And Tissue Engineering (2011- )
Journal of Biomaterials and Tissue Engineering
Member Of The International Mesostructured Material Association
International Mesostructured Material Association
Member Of The International Zeolite Association
International Zeolite Association
Tissue Engineering & Regenerative Medicine International Society
Special Research Centre Of The Australian Research Council Based At The University Of Melbourne
Particulate Fluids Processing Centre [PFPC]
Australasian Society for Biomaterials and Tissue Engineering
Australian Association for Engineering Education
Doctor of Philosophy
University of Melbourne
Bachelor of Engineering
University of Melbourne