Terence Pang

Cardinal role of the environment in stress induced changes across life stages and generations

Terence Y Pang, Jazmine DW Yaeger, Cliff H Summers, Rupshi Mitra

Journal article  |  2021  |  NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The stress response in rodents and humans is exquisitely dependent on the environmental context. The interactive element of the en..

Small Non-coding RNAs Are Dysregulated in Huntington's Disease Transgenic Mice Independently of the Therapeutic Effects of an Environmental Intervention

Celine Dubois, Geraldine Kong, Harvey Tran, Shanshan Li, Terence Y Pang, Anthony J Hannan, Thibault Renoir

Journal article  |  2021  |  MOLECULAR NEUROBIOLOGY

Huntington's disease (HD) is a neurodegenerative disorder caused by a trinucleotide repeat expansion in the huntingtin gene. Trans..

Orexin-1 receptor signaling within the lateral hypothalamus, but not bed nucleus of the stria terminalis, mediates context-induced relapse to alcohol seeking

Erin J Campbell, Mitchell KR Hill, Xavier J Maddern, Shubo Jin, Terence Y Pang, Andrew J Lawrence

Journal article  |  2020  |  JOURNAL OF PSYCHOPHARMACOLOGY

BACKGROUND: The lateral hypothalamic orexin (hypocretin) system has a well-established role in the motivation for reward. This has..

Limitations to intergenerational inheritance: subchronic paternal stress preconception does not influence offspring anxiety

KA Fennell, RGG Busby, S Li, C Bodden, SJ Stanger, B Nixon, AK Short, AJ Hannan, TY Pang

Journal article  |  2020  |  SCIENTIFIC REPORTS

Independent studies have observed that a paternal history of stress or trauma is associated with his children having a greater lik..

Preconceptual paternal environmental stimulation alters behavioural phenotypes and adaptive responses intergenerationally in Swiss mice

Lucas B Hoffmann, Mariana Rae, Priscila Marianno, Terence Y Pang, Anthony J Hannan, Rosana Camarini

Journal article  |  2020  |  PHYSIOLOGY & BEHAVIOR

Experimental research has recently revealed that paternal environmental conditions can influence the offspring phenotype through e..

Assessment of conditioned fear extinction in male and female adolescent rats

Christina J Perry, Despina E Ganella, Dao Nguyen Ly, Xin Du, Katherine D Drummond, Sarah Whittle, Terence Y Pang, Jee Hyun Kim

Journal article  |  2020  |  PSYCHONEUROENDOCRINOLOGY

Pavlovian fear conditioning and extinction have been widely studied across many species to understand emotional learning and memor..

HPA axis regulation and stress response is subject to intergenerational modification by paternal trauma and stress

Vicky Batchelor, Terence Y Pang

Journal article  |  2019  |  GENERAL AND COMPARATIVE ENDOCRINOLOGY

There is increasing evidence that one's risk for psychiatric disturbances and metabolic syndromes is influenced by their parents' ..

Novel approaches to alcohol rehabilitation: Modification of stress-responsive brain regions through environmental enrichment

Terence Y Pang, Anthony J Hannan, Andrew J Lawrence

Journal article  |  2019  |  NEUROPHARMACOLOGY

Relapse remains the most prominent hurdle to successful rehabilitation from alcoholism. The neural mechanisms underlying relapse a..

Adolescent inhalant abuse induces an endocrine disorder analogous to adrenal insufficiency

Rose Crossin, Andrew J Lawrence, Brian Oldfield, Aneta Stefanidis, Zane B Andrews, Terence Pang, Jhodie R Duncan

Conference Proceedings  |  2018  |  CLINICAL ENDOCRINOLOGY

Hypersensitivity to sertraline in the absence of hippocampal 5-HT1AR and 5-HTT gene expression changes following paternal corticosterone treatment

Arina Rawat, Jackey Guo, Thibault Renoir, Terence Y Pang, Anthony J Hannan

Journal article  |  2018  |  ENVIRONMENTAL EPIGENETICS

The male germ line is capable of transmitting a legacy of stress exposure to the next generation of offspring. This transgeneratio..