Jacqueline Heraud

What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs

Jacki E Heraud-Farlow, Carl R Walkley

Journal article  |  2020  |  OPEN BIOLOGY

Adenosine-to-inosine (A-to-I) editing is a post-transcriptional modification of RNA which changes its sequence, coding potential a..

The majority of A-to-I RNA editing is not required for mammalian homeostasis

Alistair M Chalk, Scott Taylor, Jacki E Heraud-Farlow, Carl R Walkley

Journal article  |  2019  |  GENOME BIOLOGY

BACKGROUND: Adenosine-to-inosine (A-to-I) RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sit..

Defining the functions of adenosine-to-inosine RNA editing through hematology

Jacki E Heraud-Farlow, Alistair M Chalk, Carl R Walkley

Journal article  |  2019  |  CURRENT OPINION IN HEMATOLOGY

PURPOSE OF REVIEW: The direct modification of RNA is now understood to be widespread, evolutionarily conserved and of consequence ..

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis

Jacki E Heraud-Farlow, Alistair M Chalk, Sandra E Linder, Qin Li, Scott Taylor, Joshua M White, Lokman Pang, Brian J Liddicoat, Ankita Gupte, Jin Billy Li, Carl R Walkley

Journal article  |  2017  |  GENOME BIOLOGY

BACKGROUND: Adenosine-to-inosine (A-to-I) editing of dsRNA by ADAR proteins is a pervasive epitranscriptome feature. Tens of thous..