Erica Fletcher

A method of treatment

E FLETCHER

A method of treatment

E FLETCHER

Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout.

Anna YM Wang, Vickie HY Wong, Pei Ying Lee, Bang V Bui, Stefanie Dudczig, Kirstan A Vessey, Erica L Fletcher

Journal article  |  2021  |  Scientific Reports

There is increasing evidence for the vulnerability of specific retinal ganglion cell (RGC) types in those with glaucoma and in ani..

Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration

Una Greferath, Mario Huynh, Andrew Ian Jobling, Kirstan Anne Vessey, Gene Venables, Denver Surrao, Helen Christine O'Neill, Ioannis J Limnios, Erica Lucy Fletcher

Journal article  |  2021  |  Frontiers in Cellular Neuroscience

Retinitis pigmentosa is a family of inherited retinal degenerations associated with gradual loss of photoreceptors, that ultimatel..

Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms

Kiana Kakavand, Andrew I Jobling, Ursula Greferath, Kirstan A Vessey, Robb U de Iongh, Erica L Fletcher

Journal article  |  2020  |  Frontiers in Neuroscience

Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat str..

Advances in understanding the mechanisms of retinal degenerations

Erica L Fletcher

Journal article  |  2020  |  Clinical and Experimental Optometry

Potential mechanisms of retinal ganglion cell type-specific vulnerability in glaucoma

Anna YM Wang, Pei Ying Lee, Bang Bui, Andrew Jobling, Ursula Greferath, Alice Brandli, Michael A Dixon, Quan Findlay, Erica L Fletcher, Kirstan A Vessey

Journal article  |  2020  |  Clinical and Experimental Optometry

Glaucoma is a neurodegenerative disease characterised by progressive damage to the retinal ganglion cells (RGCs), the output neuro..

Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy

Samuel Mills, Andrew Jobling, Michael Dixon, Bang Bui, Kirstan Vessey, Joanna Phipps, Ursula Greferath, Gene Venables, Vickie HY Wong, Connie HY Wong, Zheng He, Flora Hui, James Young, Josh Tonc, Elena Ivanova, Botir Sagdullaev, Erica Fletcher

Journal article  |  2020

Local blood flow control within the CNS is critical to proper function and is dependent on coordination between neurons, glia and ..

Oral delivery of a novel small molecule drug, OCX063, protects against vascular leakage and fibrosis in a rodent model of neovascular age-related macular degeneration

Michelle Pauline Papadimitriou, Zsolt Ablonczy, Andy Whitlock, Erica Fletcher, Fay Lin Khong, Darren Kelly

Conference Proceedings  |  2020  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Contribution of microglia and monocytes to the development and progression of age related macular degeneration

Erica L Fletcher

Journal article  |  2020  |  Ophthalmic & Physiological Optics

PURPOSE: Age related macular degeneration (AMD) is the leading cause of irreversible vision loss in industrialised nations. Based ..

Fluorescent Labeling and Quantification of Vesicular ATP Release Using Live Cell Imaging

Kirstan A Vessey, Tracy Ho, Andrew I Jobling, Anna Y Wang, Erica L Fletcher

Journal article  |  2020  |  Methods in molecular biology (Clifton, N.J.)

Adenosine triphosphate (ATP) is actively transported into vesicles for purinergic neurotransmission by the vesicular nucleotide tr..

Animal and Human Models of Retinal Diseases

Erica L Fletcher, Alice Pebay, Matt V Rutar, Kiana Kakavand, Anna Y Wang, Kirstan A Vessey, Andrew I Jobling, Ursula Greferath

Book Chapter  |  2020