Philippe Lehert

Bioavailability and cardiovascular effects of adrenaline administered by Anapen 500 μg auto-injector in healthy volunteers.

Thierry Duvauchelle, Philippe Robert, Yves Donazzolo, Sabrina Loyau, Bernard Orlandini, Philippe Lehert, Jeanne-Marie Lecomte, Jean-Charles Schwartz

Journal article  |  2023  |  Br J Clin Pharmacol

AIMS: Anaphylaxis guidelines recommend intramuscular adrenaline, commonly 300 μg administered using an auto-injector device. Howev..

Single-Donor and Pooling Strategies for Fecal Microbiota Transfer Product Preparation in Ulcerative Colitis: Systematic Review and Meta-Analysis

B Levast, M Fontaine, S Nancey, P Dechelotte, J Doré, P Lehert

Journal article  |  2023  |  Clinical and Translational Gastroenterology

BACKGROUND: Patients with ulcerative colitis (UC) have a less diverse microbiome than healthy subjects. Multiple studies have eval..

Pitolisant efficacy in excessive daytime sleepiness for patients with obstructive sleep apnea

C Caussé, J-L Pépin, Y Dauvilliers, V Attali, P Lehert

Journal article  |  2022  |  Sleep Medicine

Comparing symptom measurement tools in pediatric narcolepsy

Philippe Lehert, Giuseppe Plazzi

Journal article  |  2022  |  Sleep Epidemiology

Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial.

Wiebe MC Top, Philippe Lehert, Casper G Schalkwijk, Coen DA Stehouwer, Adriaan Kooy

Journal article  |  2022  |  Diabetes Obes Metab

AIM: To study the effect of metformin on plasma levels of arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylargin..

Reliability of AMH and AFC measurements and their correlation: a large multicenter study.

Philippe Arvis, Catherine Rongières, Olivier Pirrello, Philippe Lehert

Journal article  |  2022  |  J Assist Reprod Genet

PURPOSE: Anti-Müllerian hormone (AMH) and antral follicle count (AFC) are correlated with the ovarian response, but their reliabil..

Metformin and high-sensitivity cardiac troponin I and T trajectories in type 2 diabetes patients: a post-hoc analysis of a randomized controlled trial.

Johanna MG Stultiens, Wiebe MC Top, Dorien M Kimenai, Philippe Lehert, Otto Bekers, Coen DA Stehouwer, Adriaan Kooy, Steven JR Meex

Journal article  |  2022  |  Cardiovasc Diabetol

BACKGROUND: Metformin has favorable effects on cardiovascular outcomes in both newly onset and advanced type 2 diabetes, as previo..

Comparaison du Solriamfetol et du Pitolisant via une méta-analyse indirecte en termes d’efficacité, de tolérance et de rapport bénéfice/risque chez des patients souffrant d’apnée obstructive du sommeil avec somnolence diurne excessive

P Lehert, C Causse

Journal article  |  2022  |  Revue des Maladies Respiratoires Actualités

Efficacité de Pitolisant 18 mg pour réduire la somnolence diurne excessive chez les patients atteints du syndrome d’apnée obstructive du sommeil : méta-analyse des données individuelles patients

C Causse, P Lehert

Journal article  |  2022  |  Revue des Maladies Respiratoires Actualités

Efficacy of Pitolisant 20 mg in Reducing Excessive Daytime Sleepiness and Fatigue in Patients with Obstructive Sleep Apnoea Syndrome: An Individual Patient Data Meta-analysis

Philippe Lehert

Journal article  |  2021  |  CLINICAL DRUG INVESTIGATION

BACKGROUND AND OBJECTIVE: Excessive daytime sleepiness (EDS) and fatigue are major complaints in patients with obstructive sleep a..