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Prof

Wayne Phillips

Honorary
The Sir Peter Maccallum Department Of Oncology
science & technology
life sciences & biomedicine
humans
oncology
animals
mice
female
mutation
cell biology
Wayne Phillips's Profile Picture
Prof

Wayne Phillips

 
Division
Medicine, Dentistry And Health Sciences
Wayne Phillips's Profile Picture
Prof

Wayne Phillips

 

Prof. Wayne Phillips is a cellular and molecular biologist with a long-standing interest in the role of the phosphoinositide 3-kinase signalling pathway in cancer. His laboratory was one of the first to identify somatic mutations in the phosphoinositide 3-kinase family genes in human tumours and now studies the biological consequences and clinical significance of these mutations.

Currently his work is focussed on using a novel Pik3ca knock-in mouse model to investigate the role, function, and mechanism of action of Pik3ca mutations in a physiologically relevant context in a number of different tumour types. Prof. Phillips' laboratory also has a major interest in the pathogenesis of Barrett's oesophagus and is developing novel 3D cell culture systems and pre-clinical models with which to explore cellular and molecular mechanisms underlying development of Barrett's metaplasia and its progression oesophageal adenocarcinoma. He is also using genomic approaches to understand the genetics of familial Barrett's oesophagus.

Projects

Displaying the 23 most recent projects by Wayne Phillips.

23

Projects

Project Types


23

Research Grant


Scholarly Works

Displaying the 141 most recent scholarly works by Wayne Phillips.

Credentials

Positions


Honorary

The Sir Peter Maccallum Department Of Oncology

Honorary

Surgery - St Vincent'S Hospital