Mary Familari

Neural differentiation medium for human pluripotent stem cells to model physiological glucose levels in human brain

Michal E Mor, Alexandra Harvey, Mary Familari, Mitchell St Clair-Glover, Serena Viventi, Robb U de Iongh, Fergus J Cameron, Mirella Dottori

Journal article  |  2021  |  BRAIN RESEARCH BULLETIN

Cortical neurospheres (NSPs) derived from human pluripotent stem cells (hPSC), have proven to be a successful platform to investig..

Maternal Exposure to Ambient Air Pollution and Risk of Preeclampsia: A Population-Based Cohort Study in Scania, Sweden

Yumjirmaa Mandakh, Ralf Rittner, Erin Flanagan, Anna Oudin, Christina Isaxon, Mary Familari, Stefan Rocco Hansson, Ebba Malmqvist

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

The aim of this study was to investigate the risk of developing preeclampsia (PE) associated with gestational exposure to ambient ..

Exposure of trophoblast cells to fine particulate matter air pollution leads to growth inhibition, inflammation and ER stress

Mary Familari, Asa Naav, Lena Erlandsson, Robb U de Iongh, Christina Isaxon, Bo Strandberg, Thomas Lundh, Stefan R Hansson, Ebba Malmqvist

Journal article  |  2019  |  PLOS ONE

Ambient air pollution is considered a major environmental health threat to pregnant women. Our previous work has shown an associat..

Using proteomics to advance the search for potential biomarkers for preeclampsia: A systematic review and meta-analysis

Pham Hoai Nguyen Thy, Cameron James Patrick, Laura Jean Parry, Mary Familari

Journal article  |  2019  |  PLOS ONE

BACKGROUND: Preeclampsia (PE) is a leading cause of maternal and perinatal morbidity and mortality worldwide. Although predictive ..

Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells

Zahra Masoumi, Gregory E Maes, Koen Herten, Alvaro Cortes-Calabuig, Abdul Ghani Alattar, Eva Hanson, Lena Erlandsson, Eva Mezey, Mattias Magnusson, Joris R Vermeesch, Mary Familari, Stefan R Hansson

Journal article  |  2019  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preeclampsia (PE) has been associated with placental dysfunction, resulting in fetal hypoxia, accelerated erythropoiesis, and incr..

FINE PARTICULATE MATTER AIR POLLUTION CAUSES INFLAMMATION, ER STRESS AND ACTIVATES CELL DEATH IN CULTURED FIRST TRIMESTER TROPHOBLAST

Stefan R Hansson, Mary Familari, Asa Naav, Lena Erlandsson, Robb de Longh, Christina Isaxon, Ebba Malmqvist

Conference Proceedings  |  2018  |  PLACENTA

Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis

Shaghayegh Saeidi, Farnaz Shapouri, Robb U de Iongh, Franca Casagranda, Jessie M Sutherland, Patrick S Western, Eileen A McLaughlin, Mary Familari, Gary R Hime

Journal article  |  2018  |  PLOS ONE

ESRP1 regulates alternative splicing, producing multiple transcripts from its target genes in epithelial tissues. It is upregulate..

Interrogating the mechanisms underlying cognitive impairments in type 1 diabetes using human embryonic stem cells.

Michal Mor, Fergus Cameron, Mary Familari, Gurscharan Chana, A Harvey, Mirella Dottori

Conference Proceedings  |  2018

Syncytiotrophoblast derived extracellular vesicles transfer functional placental miRNAs to primary human endothelial cells

Tina Cronqvist, Dionne Tannetta, Matthias Morgelin, Mattias Belting, Ian Sargent, Mary Familari, Stefan R Hansson

Journal article  |  2017  |  SCIENTIFIC REPORTS

During the pregnancy associated syndrome preeclampsia (PE), there is increased release of placental syncytiotrophoblast extracellu..

OP 49 Air pollution effects on preeclampsia-effects by size of particles and by sources

Ebba Malmqvist, Åsa Nääv, Mary Familari, Christina Isaxon, Stefan Hansson

Journal article  |  2017  |  Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health