Prof Christopher Rowe

Professor Christopher Rowe BMBS, FRACP, MD, FAANMS is a nuclear medicine physician and neurologist, with over 20 years of experience in dementia research and patient care. He is the Director of Molecular Imaging Research at Austin Health, Melbourne, Professorial Fellow University of Melbourne, a NHMRC Practitioner Fellow and is the inaugural Director of the Australian Dementia Network.

His research focus is molecular imaging of neurodegenerative diseases, particularly AD, for better understanding, earlier more accurate detection, and to facilitate development of early therapeutic interventions. He has over 300 publications and is in the 2019 Highly Cited Researcher list of the top 1% world-wide for neuroscience with over 4,500 citations of his papers per year, and has received the 2011 US Society of Nuclear Medicine Kuhl-Lassen Award for Outstanding Contribution to Brain Imaging and the 2016 Christopher Clark Award for advancing human brain amyloid imaging.

Find out more about Christopher Rowe's experience

Christopher Rowe's highlights

FEATURED Journal article

Subjective memory decline predicts greater rates of clinical progression in preclinical Alzheimer's disease

Christopher Rowe's selected work

The Australian Dementia Network (Adnet): Bringing Together Australia’S Dementia Stakeholde..

Research Grant

Phenomenological Characterization of Memory Complaints in Preclinical and Prodromal Alzhei..

Journal article

The Australian Dementia Network (Adnet): Bringing Together Australia’S Dementia Stakeholde..

Research Grant

Prediction of Amyloid-beta Pathology in Amnestic Mild Cognitive Impairment with Neuropsych..

Journal article

The Australian Dementia Network (Adnet): Bringing Together Australia’S Dementia Stakeholde..

Research Grant

Awareness of olfactory deficits in healthy aging, amnestic mild cognitive impairment and A..

Journal article

Projects

Displaying the 14 most recent projects by Christopher Rowe.

The Australian Dementia Network (Adnet): Bringing Together Australia’S Dementia Stakeholders

Project Abstract This project proposes the development and demonstration of a label-free sensing instrument based on the integration of an e..

2018 - 2023

Active

The Australian Dementia Network (Adnet): Bringing Together Australia’S Dementia Stakeholders

Project Abstract This project proposes the development and demonstration of a label-free sensing instrument based on the integration of an e..

2018 - 2023

Active

The Australian Dementia Network (Adnet): Bringing Together Australia’S Dementia Stakeholders

Project Abstract This project proposes the development and demonstration of a label-free sensing instrument based on the integration of an e..

2018 - 2023

Active

Characterising The Muscarinic Receptor Deficit In Schizophrenia

2018 - 2018

Completed

7t Healthy Ageing Study

2015 - 2017

Completed

The Genetic And Environmental Determinants Of Amyloid Deposition In Older Individuals: An Amyloid Imaging Study Using The Twin Design

Alzheimer’s disease is characterised by the deposition of amyloid plaques in the brain. We don’t fully understand how amyloid deposition occ..

2015 - 2017

Completed

Tau And Beta-Amyloid Deposition, Microhemorrhage And Brain Function After Traumatic Brain Injury In War Veterans

2014 - 2016

Completed

Tau And Beta-Amyloid Deposition, Microhemorrhage And Brain Function After Traumatic Brain Injury In War Veterans

2014 - 2017

Completed

In Vivo Tau Imaging In Alzheimer'S Disease And Other Dementias

Alteration of the normal protein tau leads to its deposition inside the brain cells leading to their death. These deposits have been well ch..

2013 - 2015

Completed

Identifying Neuroimaging Biomarkers Of Psychosis Onset

2011 - 2015

Completed

Tracking The Development Of Alzheimer'S Disease With Beta Amyloid Imaging

A new scan called PiB PET shows the build up of amyloid protein deposits in the brain in all patients with Alzheimer's disease (AD) but also..

2011 - 2013

Completed

Benzodiazepine Receptor Changes In Seizure Focus

The Prevalence Of Alzheimer'S Disease Pathology After Traumatic Brain Injury In Veterans And Civilians: A Biomarker Study Of Beta-Amyloid And Tau

Nsv_043_05_Sag22 (P3) : Amyloid Imaging With 18f-Ab Ligand And Pet

14

Projects

Project Types

Research Grant

Research Contracts

Internal Research Grant

Scholarly Works

Displaying the 351 most recent scholarly works by Christopher Rowe.

A head-to-head comparison of cerebral blood flow SPECT and 18 F-FDG PET in the diagnosis of Alzheimer's Disease.

David P Nadebaum, Natasha Krishnadas, Aurora Mt Poon, Victor Kalff, Meir Lichtenstein, Victor L Villemagne, Gareth Jones, Christopher C Rowe

Journal article | 2020 | Internal Medicine Journal

BACKGROUND: Clinical diagnosis of Alzheimer's disease (AD) is only 70% accurate. Reduced cerebral blood flow (CBF) and metabolism ..

Effect of a 24-month physical activity program on brain changes in older adults at risk of Alzheimer's disease: the AIBL active trial

Vijay K Venkatraman, Andrew Sanderson, Kay L Cox, Kathryn A Ellis, Christopher Steward, Pramit M Phal, Alexandra Gorelik, Matthew J Sharman, Victor L Villemagne, Michelle Lai, Elizabeth Cyarto, Bernd Merkel, David Ames, Cassandra Szoeke, Christopher C Rowe, Colin L Masters, Nicola T Lautenschlager, Patricia M Desmond

Journal article | 2020 | Neurobiology of Aging

White matter hyperintensities (WMHs) are a risk factor for cognitive decline. Physical activity (PA) is associated with lower WMH...

Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer's disease

Sanka Amadoru, Vincent Dore, Catriona A McLean, Fairlie Hinton, Claire E Shepherd, Glenda M Halliday, Cristian E Leyton, Paul A Yates, John R Hodges, Colin L Masters, Victor L Villemagne, Christopher C Rowe

Journal article | 2020 | Alzheimer's Research & Therapy

BACKGROUND: The Centiloid scale was developed to standardise the results of beta-amyloid (Aβ) PET. We aimed to determine the Centi..

Increased cerebral blood flow with increased amyloid burden in the preclinical phase of alzheimer's disease

Amir Fazlollahi, Fernando Calamante, Xiaoyun Liang, Pierrick Bourgeat, Parnesh Raniga, Vincent Dore, Jurgen Fripp, David Ames, Colin L Masters, Christopher C Rowe, Alan Connelly, Victor L Villemagne, Olivier Salvado

Journal article | 2020 | Journal of Magnetic Resonance Imaging

BACKGROUND: Arterial spin labeling (ASL) is an emerging MRI technique for noninvasive measurement of cerebral blood flow (CBF) tha..

Amyloid-beta, Tau, and F-18-Fluorodeoxyglucose Positron Emission Tomography in Posttraumatic Stress Disorder

Alby Elias, Tia Cummins, Fiona Lamb, Regan Tyrrell, Vincent Dore, Rob Williams, Jeffrey Rosenfeld, Malcolm Hopwood, Victor L Villemagne, Christopher C Rowe

Journal article | 2020 | Journal of Alzheimer's Disease

BACKGROUND: Epidemiological studies suggest a relationship between posttraumatic stress disorder (PTSD) and dementia. OBJECTIVE: T..

Baseline White Matter Is Associated With Physical Fitness Change in Preclinical Alzheimer's Disease.

Vijay K Venkatraman, Christopher E Steward, Kay L Cox, Kathryn A Ellis, Pramit M Phal, Matthew J Sharman, Victor L Villemagne, Michelle MY Lai, Elizabeth V Cyarto, David Ames, Cassandra Szoeke, Christopher C Rowe, Colin L Masters, Nicola T Lautenschlager, Patricia M Desmond

Journal article | 2020 | Frontiers in Aging Neuroscience

White matter (WM) microstructure is a sensitive marker to distinguish individuals at risk of Alzheimer's disease. The association ..

Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease.

Kunal Dhiman, Veer Bala Gupta, Victor L Villemagne, Dhamidhu Eratne, Petra L Graham, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I Bush, Christopher C Rowe, Colin L Masters, David Ames, Eugene Hone, Kaj Blennow, Henrik Zetterberg, Ralph N Martins

Journal article | 2020 | Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Introduction: This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) d..

Influence of Comorbidity of Cerebrovascular Disease and Amyloid-beta on Alzheimer's Disease

Nawaf Yassi, Saima Hilal, Ying Xia, Yen Ying Lim, Rosie Watson, Hugo Kuijf, Christopher Fowler, Paul Yates, Paul Maruff, Ralph Martins, David Ames, Christopher Chen, Christopher C Rowe, Victor L Villemagne, Olivier Salvado, Patricia M Desmond, Colin L Masters

Journal article | 2020 | Journal of Alzheimer's Disease

BACKGROUND: Quantifying the contribution of cerebrovascular disease to the clinical and pathological profile of Alzheimer's diseas..

Rates of age- and amyloid β-associated cortical atrophy in older adults with superior memory performance.

Christa Dang, Nawaf Yassi, Karra D Harrington, Ying Xia, Yen Ying Lim, David Ames, Simon M Laws, Martha Hickey, Stephanie Rainey-Smith, Hamid R Sohrabi, James D Doecke, Jurgen Fripp, Olivier Salvado, Peter J Snyder, Michael Weinborn, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff, undefined AIBL Research Group

Journal article | 2019 | Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Introduction: Superior cognitive performance in older adults may reflect underlying resistance to age-associated neurodegeneration..

Validation of a priori candidate Alzheimer's disease SNPs with brain amyloid-beta deposition

Michael Vacher, Tenielle Porter, Victor L Villemagne, Lidija Milicic, Madeline Peretti, Christopher Fowler, Ralph Martins, Stephanie Rainey-Smith, David Ames, Colin L Masters, Christopher C Rowe, James D Doecke, Simon M Laws

Journal article | 2019 | Scientific Reports

The accumulation of brain amyloid β (Aβ) is one of the main pathological hallmarks of Alzheimer's disease (AD). However, the role ..

Application of the NIA-AA Research Framework: Towards a Biological Definition of Alzheimer's Disease using Cerebrospinal Fluid Biomarkers in the AIBL Study

SC Burnham, PM Coloma, Q-X Li, S Collins, G Savage, S Laws, J Doecke, P Maruff, RN Martins, D Ames, CC Rowe, CL Masters, VL Villemagne

Journal article | 2019 | The journal of prevention of Alzheimer's disease

Visual Paired Associate Learning Deficits Associated With Elevated Beta-Amyloid in Cognitively Normal Older Adults

Jenalle E Baker, Robert H Pietrzak, Simon M Laws, David Ames, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff, Yen Ying Lim

Journal article | 2019 | Neuropsychology

OBJECTIVE: Previous studies have shown that paired associate learning (PAL), a type of episodic memory, is impaired in early Alzhe..

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease

Xavier Hadoux, Flora Hui, Jeremiah KH Lim, Colin L Masters, Alice Pebay, Sophie Chevalier, Jason Ha, Samantha Loi, Christopher J Fowler, Christopher Rowe, Victor L Villemagne, Edward N Taylor, Christopher Fluke, Jean-Paul Soucy, Frederic Lesage, Jean-Philippe Sylvestre, Pedro Rosa-Neto, Sulantha Mathotaarachchi, Serge Gauthier, Ziad S Nasreddine, et al.

Journal article | 2019 | Nature Communications

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid beta-Associated Cognitive Decline in Older Adults

Christa Dang, Karra D Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M Laws, Nawaf Yassi, Martha Hickey, Stephanie R Rainey-Smith, Joanne Robertson, Christopher C Rowe, Hamid R Sohrabi, Olivier Salvado, Michael Weinborn, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article | 2019 | Archives of Clinical Neuropsychology

Objective: To prospectively examine 8-year risk of clinical disease progression to mild cognitive impairment (MCI)/dementia in old..

Avoiding methodological bias in studies of amyloid imaging results disclosure

Carl Taswell, Cheryl Donohue, Maree T Mastwyk, Andrea G Louey, Jacqueline Giummarra, Joanne Robertson, David G Darby, Colin L Masters, Christopher C Rowe

Journal article | 2019 | Alzheimer's Research & Therapy

Comparison of F-18-florbetaben quantification results using the standard Centiloid, MR-based, and MR-less CapAIBL (R) approaches: Validation against histopathology

Vincent Dore, Santiago Bullich, Christopher C Rowe, Pierrick Bourgeat, Salamata Konate, Osama Sabri, Andrew W Stephens, Henryk Barthel, Jurgen Fripp, Colin L Masters, Ludger Dinkelborg, Olivier Salvado, Victor L Villemagne, Susan De Santi

Journal article | 2019 | Alzheimer's & Dementia

COMT val158met is not associated with Aβ-amyloid and APOE ε4 related cognitive decline in cognitively normal older adults.

Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Hamid R Sohrabi, Madeline Peretti, Yen Ying Lim, Michael Weinborn, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article | 2019 | IBRO Reports

The non-synonymous single nucleotide polymorphism (SNP), Val158Met within the Catechol-O-methyltransferase (COMT) gene has been as..

In vivo imaging of brain muscarinic receptors with F-18 Flurobenzyl Dexetimide: First in human studies

Christopher Rowe, Brian Dean, Uwe Ackermann, Rachel Goh, Rodney Guzman, Richard Kanaan, Lee Chong, Vincent Dore, Svetlana Bozinovski, Colin Masters, Victor Villemagne

Conference Proceedings | 2019 | JOURNAL OF NUCLEAR MEDICINE

Assessing global and regional A beta-amyloid deposition in the brain with multiple A beta-tracers using the Centiloid scale

Victor Villemagne, Samantha Burnham, Pierrick Bourgeat, Vincent Dore, Simon Laws, Olivier Salvado, Jurgen Fripp, Ralph Martins, Colin Masters, Christopher Rowe

Conference Proceedings | 2019 | JOURNAL OF NUCLEAR MEDICINE

Tau imaging with F-18-MK6240 in Alzheimer's disease and Traumatic Brain Injury

Christopher Rowe, Vincent Dore, Amelia Hicks, Jennifer Ponsford, Rachel Mulligan, Regan Tyrrell, Rodney Guzman, Fiona Lamb, Pierrick Bourgeat, Malcolm Hopwood, Jurgen Fripp, Colin Masters, Victor Villemagne

Conference Proceedings | 2019 | JOURNAL OF NUCLEAR MEDICINE

Imaging of tau deposits in adults with Niemann-Pick type C disease: a case-control study

Victor L Villemagne, D Velakoulis, V Dore, S Bozinoski, CL Masters, CC Rowe, Mark Walterfang

Journal article | 2019 | European Journal of Nuclear Medicine and Molecular Imaging

Phantom measurement predicts the impact of image reconstruction on Florbetapir SUVR quantification

Robert Williams, Leigh Johnston, Vincent Dore, Graeme O'Keefe, Jason Callahan, Zhihan Xu, Shuning Zheng, Bradford Moffat, Colin Masters, Christopher Rowe

Conference Proceedings | 2019 | JOURNAL OF NUCLEAR MEDICINE

Klotho allele status is not associated with A beta and APOE epsilon 4-related cognitive decline in preclinical Alzheimer's disease

Tenielle Porter, Samantha C Burnham, Lidija Milicic, Greg Savage, Paul Maruff, Yen Ying Lim, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article | 2019 | Neurobiology of Aging

PET IMAGING OF BRAIN MUSCARINIC M1 RECEPTORS WITH F-18-FLUROBENZYL DEXETIMIDE: FIRST IN HUMAN STUDIES

CC Rowe, B Dean, U Ackermann, R Goh, R Guzman, R Kanaan, L Chong, V Dore, VL Villemagne

Conference Proceedings | 2019 | INTERNAL MEDICINE JOURNAL

MK-6240-PET NEUROFIBRILLARY TANGLE PATTERN SUBTYPES ARE ASSOCIATED WITH DISTINCT MEMORY AND COGNITIVE PERFORMANCE

S Schultz, CC Rowe, V Dore, R Mulligan, VL Villemagne

Conference Proceedings | 2019 | INTERNAL MEDICINE JOURNAL

Multisite study of the relationships between antemortem [C-11]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

Renaud La Joie, Nagehan Ayakta, William W Seeley, Ewa Borys, Adam L Boxer, Charles Decarli, Vincent Dore, Lea T Grinberg, Eric Huang, Ji-Hye Hwang, Milos D Ikonomovic, Clifford Jack, William J Jagusth, Lee-Way Jin, William E Klunk, Julia Kofler, Orit H Lesman-Segev, Samuel N Lockhart, Val J Lowe, Colin L Masters, et al.

Journal article | 2019 | Alzheimer's & Dementia

Metabolic patterns and seizure outcomes following anterior temporal lobectomy

Varduhi Cahill, Benjamin Sinclair, Charles B Malpas, Anne M McIntosh, Zhibin Chen, Lucy E Vivash, Marie F O'Shea, Sarah J Wilson, Patricia M Desmond, Salvatore U Berlangieri, Rodney J Hicks, Christopher C Rowe, Andrew P Morokoff, James A King, Gavin C Fabinyi, Andrew H Kaye, Patrick Kwan, Samuel F Berkovic, Terence J O'Brien

Journal article | 2019 | Annals of Neurology

A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease

Nicholas J Ashton, Alejo J Nevado-Holgado, Imelda S Barber, Steven Lynham, Veer Gupta, Pratishtha Chatterjee, Kathryn Goozee, Eugene Hone, Steve Pedrini, Kaj Blennow, Michael Scholl, Henrik Zetterber, Kathryn A Ellis, Ashley Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Dag Aarsland, John Powell, et al.

Journal article | 2019 | Science Advances

"Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia"

William Jagust, Clifford R Jack, David A Bennett, Kaj Blennow, Samantha Budd Haeberlein, David M Holtzman, Frank Jessen, Jason Karlawish, Enchi Liu, Jose Luis Molinuevo, Thomas Montine, Creighton Phelps, Katherine P Rankin, Christopher C Rowe, Philip Scheltens, Eric Siemers, Reisa Sperling

Journal article | 2019 | Alzheimer's & Dementia

Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease.

Saori Hata, Chiori Omori, Ayano Kimura, Haruka Saito, Nobuyuki Kimura, Veer Gupta, Steve Pedrini, Eugene Hone, Pratishtha Chatterjee, Kevin Taddei, Kensaku Kasuga, Takeshi Ikeuchi, Masaaki Waragai, Masaki Nishimura, Anqi Hu, Tadashi Nakaya, Laurent Meijer, Masahiro Maeda, Tohru Yamamoto, Colin L Masters, et al.

Journal article | 2019 | Alzheimer's & Dementia: Translational Research & Clinical Interventions

Introduction: Neuronal p3-Alcβ peptides are generated from the precursor protein Alcadein β (Alcβ) through cleavage by α- and γ-se..

A Randomized Controlled Trial of Adherence to a 24-Month Home-Based Physical Activity Program and the Health Benefits for Older Adults at Risk of Alzheimer's Disease: The AIBL Active-Study

Kay L Cox, Elizabeth Cyarto, Kathryn A Ellis, David Ames, Patricia Desmond, Pramit Phal, Matthew J Sharman, Cassandra Szoeke, Christopher C Rowe, Colin L Masters, Emily You, Sally Burrows, Michelle MY Lai, Nicola T Lautenschlager

Journal article | 2019 | Journal of Alzheimer's Disease

BACKGROUND: Previous studies have demonstrated that physical activity (PA) interventions can improve physical and cognitive outcom..

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease

Tenielle Porter, Samantha C Burnham, Greg Savage, Yen Ying Lim, Paul Maruff, Lidija Milicic, Madeline Peretti, David Ames, Colin L Masters, Ralph N Martins, Stephanie Rainey-Smith, Christopher C Rowe, Olivier Salvado, Kevin Taddei, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article | 2018 | Frontiers in Aging Neuroscience

Centiloid scaling for quantification of brain amyloid with [F-18]flutemetamol using multiple processing methods

Mark R Battle, Lovena Chedumbarum Pillay, Val J Lowe, David Knopman, Bradley Kemp, Christopher C Rowe, Vincent Dore, Victor L Villemagne, Christopher J Buckley

Journal article | 2018 | EJNMMI Research

Standardization of amyloid quantitation with florbetapir standardized uptake value ratios to the Centiloid scale

Michael Navitsky, Abhinay D Joshi, Ian Kennedy, William E Klunk, Christopher C Rowe, Dean F Wong, Michael J Pontecorvo, Mark A Mintun, Michael D Devous

Journal article | 2018 | Alzheimer's & Dementia

Implementing the centiloid transformation for C-11-PiB and beta-amyloid F-18-PET tracers using CapAIBL

Pierrick Bourgeat, Vincent Dore, Jurgen Fripp, David Ames, Colin L Masters, Olivier Salvado, Victor L Villemagne, Christopher C Rowe

Journal article | 2018 | NeuroImage

Diagnostic accuracy of imaging brain vesicular monoamine transporter type 2 (VMAT2) in clinically uncertain parkinsonian syndrome (CUPS): a 3-year follow-up study in community patients

San San Xu, Paschal K Alexander, Yenni Lie, Vincent Dore, Svetlana Bozinovski, Rachel S Mulligan, Kenneth Young, Victor L Villemagne, Christopher C Rowe

Journal article | 2018 | BMJ Open

Prevalence of amyloid-beta pathology in distinct variants of primary progressive aphasia

David Bergeron, Maria L Gorno-Tempini, Gil D Rabinovici, Miguel A Santos-Santos, William Seeley, Bruce L Miller, Yolande Pijnenburg, M Antoinette Keulen, Colin Groot, Bart NM van Berckel, Wiesje M van der Flier, Philip Scheltens, Jonathan D Rohrer, Jason D Warren, Jonathan M Schott, Nick C Fox, Raquel Sanchez-Valle, Oriol Grau-Rivera, Ellen Gelpi, Harro Seelaar, et al.

Journal article | 2018 | Annals of Neurology

Mediterranean diet adherence and rate of cerebral A beta-amyloid accumulation: Data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

Stephanie R Rainey-Smith, Yian Gu, Samantha L Gardener, James D Doecke, Victor L Villemagne, Belinda M Brown, Kevin Taddei, Simon M Laws, Hamid R Sohrabi, Michael Weinborn, David Ames, Christopher Fowler, S Lance Macaulay, Paul Maruff, Colin L Masters, Olivier Salvado, Christopher C Rowe, Nikolaos Scarmeas, Ralph N Martins

Journal article | 2018 | Translational Psychiatry

Trajectories of Irregular Word Reading Ability as a Proxy for Premorbid Intelligence in Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Aging: A Longitudinal Study

Michael Weinborn, Romola S Bucks, Hamid R Sohrabi, Stephanie R Rainey-Smith, Belinda M Brown, Samantha L Gardener, Aleksandra Gozt, Daniel Christensen, Greg Savage, Simon M Laws, Kevin Taddei, Paul Maruff, Joanne S Robertson, Kathryn A Ellis, David Ames, Colin L Masters, Christopher C Rowe, Ralph N Martins

Journal article | 2018 | Psychological Assessment

Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease

Karra D Harrington, Adrian Schembri, Yen Ying Lim, Christa Dang, David Ames, Jason Hassenstab, Simon M Laws, Stephanie Rainey-Smith, Joanne Robertson, Christopher C Rowe, Hamid R Sohrabi, Olivier Salvado, Michael Weinborn, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article | 2018 | Neurobiology of Aging

The effect of preclinical Alzheimer's disease on age-related changes in intelligence in cognitively normal older adults

Karra D Harrington, Christa Dang, Yen Ying Lim, David Ames, Simon M Laws, Robert H Pietrzak, Stephanie Rainey-Smith, Joanne Robertson, Christopher C Rowe, Olivier Salvado, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article | 2018 | Intelligence

Sex, amyloid, and APOE epsilon 4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts

Rachel F Buckley, Elizabeth C Mormino, Rebecca E Amariglio, Michael J Properzi, Jennifer S Rabin, Yen Ying Lim, Kathryn V Papp, Heidi IL Jacobs, Samantha Burnham, Bernard J Hanseeuw, Vincent Dore, Annette Dobson, Colin L Masters, Michael Waller, Christopher C Rowe, Paul Maruff, Michael C Donohue, Dorene M Rentz, Dylan Kirn, Trey Hedden, et al.

Journal article | 2018 | Alzheimer's & Dementia

Prevalence of the apolipoprotein E epsilon 4 allele in amyloid beta positive subjects across the spectrum of Alzheimer's disease

Niklas Mattsson, Colin Groot, Willemijn J Jansen, Susan M Landau, Victor L Villemagne, Sebastiaan Engelborghs, Mark M Mintun, Alberto Lleo, Jose Luis Molinuevo, William J Jagust, Giovanni B Frisoni, Adrian Ivanoiu, Gael Chetelat, Catarina Resende de Oliveira, Karen M Rodrigue, Johannes Kornhuber, Anders Wallin, Aleksandra Klimkowicz-Mrowiec, Ramesh Kandimalla, Julius Popp, et al.

Journal article | 2018 | Alzheimer's & Dementia

O2-15-03: DIFFERENTIAL RISK FACTORS FOR PROGRESSION TO MCI/DEMENTIA BY AMYLOID-BETA STATUS

Christa Dang, Karra D Harrington, Yen Lim, Nawaf Yassi, Martha Hickey, David Ames, Christopher C Rowe, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article | 2018 | Alzheimer's & Dementia

Baseline Amnestic Severity Predicts Progression From Amnestic Mild Cognitive Impairment to Alzheimer Disease Dementia at 3 Years

Nicholas I Bradfield, Kathryn A Ellis, Greg Savage, Paul Maruff, Samantha Burnham, David Darby, Nicola T Lautenschlager, Ralph N Martins, Colin L Masters, Stephanie R Rainey-Smith, Joanne Robertson, Christopher Rowe, Michael Woodward, David Ames

Journal article | 2018 | Alzheimer Disease & Associated Disorders

Imaging tau and amyloid-beta proteinopathies in Alzheimer disease and other conditions (vol 14, pg 225, 2018)

Victor L Villemagne, Vincent Dore, Samantha C Burnham, Colin L Masters, Christopher C Rowe

Journal article | 2018 | Nature Reviews Neurology

In Figure 1 of this article as originally published, the chemical structure at bottom right was incorrectly labelled 18F-PM-PBB3. ..

P1-006: EXAMINING THE RESILIENCE OF SUPERAGERS: RISK OF CLINICAL PROGRESSION AND Aβ-ASSOCIATED MEMORY DECLINE OVER 8 YEARS

Christa Dang, Yen Lim, Karra D Harrington, Nawaf Yassi, Martha Hickey, David Ames, Christopher C Rowe, Victor L Villemagne, Colin L Masters, Paul Maruff

Journal article | 2018 | Alzheimer's & Dementia

Reply: Cortical tau pathology: a major player in fibre-specific white matter reductions in Alzheimer's disease?

Remika Mito, David Raffelt, Thijs Dhollander, David N Vaughan, J-Donald Tournier, Olivier Salvado, Amy Brodtmann, Christopher C Rowe, Victor L Villemagne, Alan Connelly

Journal article | 2018 | Brain

To tau or to MAO-B? Most of the F-18-THK5351 signal is blocked by selegiline

Victor Villemagne, Vincent Dore, Nobuyuki Okamura, David Baxendale, Ryuichi Harada, Rachel Mulligan, Shozo Furumoto, Olivier Salvado, Kazuhiro Yanai, Colin Masters, Christopher Rowe

Conference Proceedings | 2018 | JOURNAL OF NUCLEAR MEDICINE

Comparing Amyloid PET Tracers and Interpretation Strategies: First Results from the CAPTAINs Study

Gerard Bischof, Peter Bartenstein, Henryk Barthel, Bart Van Berckel, Vincent Dore, Thilo Van Eimeren, Norman Foster, Jochen Hammes, Adriaan Lammertsma, Satoshi Minoshima, Christopher Rowe, Osama Sabri, John Seibyl, Koen Van Laere, Rik Vandenberghe, Victor Villemagne, Igor Yakushev, Alexander Drzezga

Conference Proceedings | 2018 | JOURNAL OF NUCLEAR MEDICINE

Correlation of Amyloid PET in Centiloid units with neuropathological findings in Alzheimer's disease

Christopher Rowe, Sanka Amadoru, Vincent Dore, Catriona McLean, Fairley Hinton, Claire Shepherd, Glenda Halliday, Cristian Leyton, John Hodges, Colin Masters, Victor Villemagne

Conference Proceedings | 2018 | JOURNAL OF NUCLEAR MEDICINE

Tau Imaging in Alzheimer's Disease with F-18-MK6240, a second generation selective tau tracer

Christopher Rowe, Vincent Dore, Rachel Mulligan, Fiona Lamb, Pierrick Bourgeat, Tia Cummins, Olivier Salvado, Colin Masters, Victor Villemagne

Conference Proceedings | 2018 | JOURNAL OF NUCLEAR MEDICINE

Evaluation of F-18-PI-2620, a second-generation selective tau tracer for the assessment of Alzheimer's and non-Alzheimer's tauopathies

Victor Villemagne, Vincent Dore, Rachel Mulligan, Fiona Lamb, Pierrick Bourgeat, Olivier Salvado, Colin Masters, Christopher Rowe

Conference Proceedings | 2018 | JOURNAL OF NUCLEAR MEDICINE

Imaging tau and amyloid-beta proteinopathies in Alzheimer disease and other conditions

Victor L Villemagne, Vincent Dore, Samantha C Burnham, Colin L Masters, Christopher C Rowe

Journal article | 2018 | Nature Reviews Neurology

Association of beta-Amyloid and Apolipoprotein E epsilon 4 With Memory Decline in Preclinical Alzheimer Disease

Yen Ying Lim, Pawel Kalinowski, Robert H Pietrzak, Simon M Laws, Samantha C Burnham, David Ames, Victor L Villemagne, Christopher J Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Christopher C Rowe, Colin L Masters, Paul T Maruff

Journal article | 2018 | JAMA Neurology

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Clifford R Jack, David A Bennett, Kaj Blennow, Maria C Carrillo, Billy Dunn, Samantha Budd Haeberlein, David M Holtzman, William Jagust, Frank Jessen, Jason Karlawish, Enchi Liu, Jose Luis Molinuevo, Thomas Montine, Creighton Phelps, Katherine P Rankin, Christopher C Rowe, Philip Scheltens, Eric Siemers, Heather M Snyder, Reisa Sperling, et al.

Journal article | 2018 | Alzheimer's & Dementia

Amyloid burden and incident depressive symptoms in preclinical Alzheimer's disease

Stephanie Perin, Karra D Harrington, Yen Ying Lim, Kathryn Ellis, David Ames, Robert H Pietrzak, Adrian Schembri, Stephanie Rainey-Smith, Olivier Salvado, Simon M Laws, Ralph N Martins, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff

Journal article | 2018 | Journal of Affective Disorders

Fibre-specific white matter reductions in Alzheimer's disease and mild cognitive impairment

Remika Mito, David Raffelt, Thijs Dhollander, David N Vaughan, J-Donald Tournier, Olivier Salvado, Amy Brodtmann, Christopher C Rowe, Victor L Villemagne, Alan Connelly

Journal article | 2018 | Brain

Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain A beta-amyloid burden

Stephanie R Rainey-Smith, Gavin N Mazzucchelli, Victor L Villemagne, Belinda M Brown, Tenielle Porter, Michael Weinborn, Romola S Bucks, Lidija Milicic, Hamid R Sohrabi, Kevin Taddei, David Ames, Paul Maruff, Colin L Masters, Christopher C Rowe, Olivier Salvado, Ralph N Martins, Simon M Laws

Journal article | 2018 | Translational Psychiatry

The glymphatic system is postulated to be a mechanism of brain Aβ-amyloid clearance and to be most effective during sleep. Ablatio..

High performance plasma amyloid-beta biomarkers for Alzheimer's disease

Akinori Nakamura, Naoki Kaneko, Victor L Villemagne, Takashi Kato, James Doecke, Vincent Dore, Chris Fowler, Qiao-Xin Li, Ralph Martins, Christopher Rowe, Taisuke Tomita, Katsumi Matsuzaki, Kenji Ishii, Kazunari Ishii, Yutaka Arahata, Shinichi Iwamoto, Kengo Ito, Koichi Tanaka, Colin L Masters, Katsuhiko Yanagisawa

Journal article | 2018 | Nature

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE epsilon 4-positive cognitively normal adults with high A beta-amyloid burden

Tenielle Porter, Samantha C Burnham, Vincent Dore, Greg Savage, Pierrick Bourgeat, Kimberly Begemann, Lidija Milicic, David Ames, Ashley I Bush, Paul Maruff, Colin L Masters, Christopher C Rowe, Stephanie Rainey-Smith, Ralph N Martins, David Groth, Giuseppe Verdile, Victor L Villemagne, Simon M Laws

Journal article | 2018 | Scientific Reports

Self-reported confusion is related to global and regional beta-amyloid: data from the Women's healthy ageing project

Georgia E McCluskey, Paul Yates, Victor L Villemagne, Christopher Rowe, Cassandra EI Szoeke

Journal article | 2018 | Brain Imaging and Behavior

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study

Sophie E Holmes, Irina Esterlis, Carolyn M Mazure, Yen Ying Lim, David Ames, Stephanie Rainey-Smith, Chris Fowler, Kathryn Ellis, Ralph N Martins, Olivier Salvado, Vincent Dore, Victor L Villemagne, Christopher C Rowe, Simon M Laws, Colin L Masters, Robert H Pietrzak, Paul Maruff

Journal article | 2018 | International Journal of Geriatric Psychiatry

Episodic Memory and Learning Dysfunction Over an 18-Month Period in Preclinical and Prodromal Alzheimer's Disease

Jenalle E Baker, Yen Ying Lim, Judith Jaeger, David Ames, Nicola T Lautenschlager, Joanne Robertson, Robert H Pietrzak, Peter J Snyder, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff