Christopher Rowe

Advances in Brain Amyloid Imaging.

Natasha Krishnadas, Victor L Villemagne, Vincent Doré, Christopher C Rowe

Journal article  |  2021  |  Seminars in Nuclear Medicine

Amyloid-β (Aβ) PET imaging has now been available for over 15 years. The ability to detect Aβ in vivo has greatly improved the cli..

Androgen receptor CAG repeat length as a moderator of the relationship between free testosterone levels and cognition.

Sherilyn Tan, Tenielle Porter, Romola S Bucks, Michael Weinborn, Lidija Milicic, Ailsa Brown, Stephanie R Rainey-Smith, Kevin Taddei, David Ames, Colin L Masters, Paul Maruff, Greg Savage, Christopher C Rowe, Victor L Villemagne, Belinda Brown, Hamid R Sohrabi, Simon M Laws, Ralph N Martins, undefined AIBL Research Group

Journal article  |  2021  |  Hormones and Behavior

Age-related decrease in testosterone levels is a potential risk factor for cognitive decline in older men. However, observational ..

Association of β-Amyloid Level, Clinical Progression, and Longitudinal Cognitive Change in Normal Older Individuals.

Laura M van der Kall, Thanh Truong, Samantha C Burnham, Vincent Doré, Rachel S Mulligan, Svetlana Bozinovski, Fiona Lamb, Pierrick Bourgeat, Jurgen Fripp, Stephanie Schultz, Yen Y Lim, Simon M Laws, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Paul Maruff, Colin L Masters, et al.

Journal article  |  2021  |  Neurology

OBJECTIVE: To determine the effect of β-amyloid (Aβ) level on progression risk to mild cognitive impairment (MCI) or dementia and ..

Aggregation of Abnormal Memory Scores and Risk of Incident Alzheimer's Disease Dementia: A Measure of Objective Memory Impairment in Amnestic Mild Cognitive Impairment

Nicholas Bradfield, Kathryn A Ellis, Greg Savage, Paul Maruff, Samantha Burnham, David Darby, Nicola T Lautenschlager, Ralph N Martins, Colin L Masters, Stephanie R Rainey-Smith, Joanne Robertson, Christopher Rowe, Michael Woodward, David Ames

Journal article  |  2021  |  Journal of the International Neuropsychological Society

OBJECTIVES: The criteria for objective memory impairment in mild cognitive impairment (MCI) are vaguely defined. Aggregating the n..

Non-negative matrix factorisation improves Centiloid robustness in longitudinal studies

Pierrick Bourgeat, Vincent Dore, James Doecke, David Ames, Colin L Masters, Christopher C Rowe, Jurgen Fripp, Victor L Villemagne

Journal article  |  2021  |  NeuroImage

BACKGROUND: Centiloid was introduced to harmonise β-Amyloid (Aβ) PET quantification across different tracers, scanners and analysi..

Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.

James M Roe, Didac Vidal-Piñeiro, Øystein Sørensen, Andreas M Brandmaier, Sandra Düzel, Hector A Gonzalez, Rogier A Kievit, Ethan Knights, Simone Kühn, Ulman Lindenberger, Athanasia M Mowinckel, Lars Nyberg, Denise C Park, Sara Pudas, Melissa M Rundle, Kristine B Walhovd, Anders M Fjell, René Westerhausen, undefined Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing

Journal article  |  2021  |  Nature Communications

Aging and Alzheimer's disease (AD) are associated with progressive brain disorganization. Although structural asymmetry is an orga..

Relationship between amyloid and tau levels and its impact on tau spreading

Vincent Dore, Natasha Krishnadas, Pierrick Bourgeat, Kun Huang, Shenpeng Li, Samantha Burnham, Colin L Masters, Jurgen Fripp, Victor L Villemagne, Christopher C Rowe

Journal article  |  2021  |  European Journal of Nuclear Medicine and Molecular Imaging

PURPOSE: Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, ..

Mesial temporal tau is related to worse cognitive performance and greater neocortical tau load in amyloid-beta-negative cognitively normal individuals

Colin Groot, Vincent Dore, Joanne Robertson, Samantha C Burnham, Greg Savage, Rik Ossenkoppele, Christopher C Rowe, Victor L Villemagne

Journal article  |  2021  |  Neurobiology of Aging

We examined whether mesial temporal (Me) tau relates to cognitive performance in 47 amyloid-β (Aβ)-negative, cognitively normal ol..

What is T ? A Gordian Knot of Tracers, Thresholds & Topographies.

Victor L Villemagne, Brian J Lopresti, Vincent Dore, Dana Tudorascu, Milos D Ikonomovic, Samantha Burnham, Davneet Minhas, Tharick A Pascoal, N Scott Mason, Beth Snitz, Howard Aizenstein, Chester A Mathis, Oscar Lopez, Christopher C Rowe, William E Klunk, Ann D Cohen

Journal article  |  2020  |  Journal of Nuclear Medicine

In this review we examine, in the context of the AT(N) framework, the available evidence as well as the potential alternatives on ..

Case Report: F-18-MK6240 Tau Positron Emission Tomography Pattern Resembling Chronic Traumatic Encephalopathy in a Retired Australian Rules Football Player

Natasha Krishnadas, Vincent Dore, Fiona Lamb, Colin Groot, Paul McCrory, Rodney Guzman, Rachel Mulligan, Kun Huang, Meaghan O'Donnell, Jennie Ponsford, Malcolm Hopwood, Victor L Villemagne, Christopher C Rowe

Journal article  |  2020  |  Frontiers in Neurology

Introduction: It remains unclear if tau imaging may assist diagnosis of chronic traumatic encephalopathy (CTE). Flortaucipir PET h..