Laura Forrest

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

Iris Kramer, Maartje J Hooning, Nasim Mavaddat, Michael Hauptmann, Renske Keeman, Ewout W Steyerberg, Daniele Giardiello, Antonis C Antoniou, Paul DP Pharoah, Sander Canisius, Zumuruda Abu-Ful, Irene L Andrulis, Hoda Anton-Culver, Kristan J Aronson, Annelie Augustinsson, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, et al.

Journal article  |  2020  |  American Journal of Human Genetics

Previous research has shown that polygenic risk scores (PRSs) can be used to stratify women according to their risk of developing ..

The art and science of recruitment to a cancer rapid autopsy programme: A qualitative study exploring patient and clinician experiences.

Erin Tutty, Philomena Horsley, Rowan Forbes Shepherd, Laura E Forrest

Journal article  |  2020  |  Palliative Medicine

BACKGROUND: CASCADE is a successful, Australia-first cancer rapid autopsy programme. Patients are recruited to the programme by th..

Finding the five-year window: A qualitative study examining young women's decision-making and experience of using tamoxifen to reduceBRCA1/2breast cancer risk

Laura E Forrest, Rowan Forbes Shepherd, Mary-Anne Young, Louise A Keogh, Paul A James

Journal article  |  2020  |  Psycho-Oncology

OBJECTIVE: Tamoxifen has been demonstrated to reduce breast cancer risk in high-risk, premenopausal women. Yet, very few young wom..

Social media usage in family communication about genetic information: 'I no longer speak with my sister but she needed to know'

Sarah Leighton, Laura E Forrest, Mary-Anne Young, Martin B Delatycki, Elly Lynch

Journal article  |  2020  |  Journal of Genetic Counseling

The use of social media has become a ubiquitous form of communication. Little is known about whether social media is used in famil..

"I need to know if I'm going to die young": Adolescent and young adult experiences of genetic testing for Li-Fraumeni syndrome

Rowan Forbes Shepherd, Allison Werner-Lin, Louise A Keogh, Martin B Delatycki, Laura E Forrest

Journal article  |  2020  |  Journal of Psychosocial Oncology

Purpose: This study explored the genetic testing experiences of adolescents and young adults (AYAs; aged 15-39 years) with, or at ..

Parental experiences and genetic counsellor roles in Pierre Robin sequence

Rhiannon Sandow, Nicky M Kilpatrick, Tiong Yang Tan, Supriya Raj, Laura Elenor Forrest

Journal article  |  2020  |  Journal of Community Genetics

Pierre Robin sequence (PRS) is a craniofacial abnormality comprising micrognathia, glossoptosis and airway obstruction, which can ..

ARE VICTORIAN WOMEN INTERESTED IN RISK STRATIFIED BREAST SCREENING?

J Lippey, L Keogh, GB Mann, I Campbell, L Forrest

Conference Proceedings  |  2020  |  BREAST

Health professionals' practice for young people with, or at risk of, Li-Fraumeni syndrome: An Australasian survey

Rowan Forbes Shepherd, Louise A Keogh, Allison Werner-Lin, Martin B Delatycki, Laura E Forrest

Journal article  |  2019  |  Journal of Genetic Counseling

Li-Fraumeni syndrome (LFS), a rare cancer syndrome caused by pathogenic germline variants in TP53, has serious implications for ad..

Development and validation of a targeted gene sequencing panel for application to disparate cancers

Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, undefined kConFab, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, et al.

Journal article  |  2019  |  Scientific Reports

Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology ..

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna Kiiski, Taru A Muranen, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Manjeet K Bolla, Goska Leslie, Cora M Aalfs, Muriel A Adank, Julian Adlard, Simona Agata, Karen Cadoo, Bjarni A Agnarsson, Thomas Ahearn, et al.

Journal article  |  2019  |  npj Breast Cancer

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1..