Paul Maruff

Association of β-Amyloid Level, Clinical Progression, and Longitudinal Cognitive Change in Normal Older Individuals.

Laura M van der Kall, Thanh Truong, Samantha C Burnham, Vincent Doré, Rachel S Mulligan, Svetlana Bozinovski, Fiona Lamb, Pierrick Bourgeat, Jurgen Fripp, Stephanie Schultz, Yen Y Lim, Simon M Laws, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Paul Maruff, Colin L Masters, et al.

Journal article  |  2021  |  Neurology

OBJECTIVE: To determine the effect of β-amyloid (Aβ) level on progression risk to mild cognitive impairment (MCI) or dementia and ..

Aggregation of Abnormal Memory Scores and Risk of Incident Alzheimer's Disease Dementia: A Measure of Objective Memory Impairment in Amnestic Mild Cognitive Impairment.

Nicholas I Bradfield, Kathryn A Ellis, Greg Savage, Paul Maruff, Samantha Burnham, David Darby, Nicola T Lautenschlager, Ralph N Martins, Colin L Masters, Stephanie R Rainey-Smith, Joanne Robertson, Christopher Rowe, Michael Woodward, David Ames

Journal article  |  2021  |  Journal of the International Neuropsychological Society

OBJECTIVES: The criteria for objective memory impairment in mild cognitive impairment (MCI) are vaguely defined. Aggregating the n..

Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.

James M Roe, Didac Vidal-Piñeiro, Øystein Sørensen, Andreas M Brandmaier, Sandra Düzel, Hector A Gonzalez, Rogier A Kievit, Ethan Knights, Simone Kühn, Ulman Lindenberger, Athanasia M Mowinckel, Lars Nyberg, Denise C Park, Sara Pudas, Melissa M Rundle, Kristine B Walhovd, Anders M Fjell, René Westerhausen, undefined Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing

Journal article  |  2021  |  Nature Communications

Aging and Alzheimer's disease (AD) are associated with progressive brain disorganization. Although structural asymmetry is an orga..

BDNF VAL66MET polymorphism and memory decline across the spectrum of Alzheimer's disease

Yen Ying Lim, Simon M Laws, Stephanie Perin, Robert H Pietrzak, Christopher Fowler, Colin L Masters, Paul Maruff

Journal article  |  2021  |  Genes Brain & Behavior

The brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism has been shown to moderate the extent to which memory ..

Acute neuroimmune stimulation impairs verbal memory in adults: A PET brain imaging study

Eric A Woodcock, Ansel T Hillmer, Christine M Sandiego, Paul Maruff, Richard E Carson, Kelly P Cosgrove, Robert H Pietrzak

Journal article  |  2021  |  Brain Behavior and Immunity

Psychiatric and neurologic disorders are often characterized by both neuroinflammation and cognitive dysfunction. To date, however..

The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans.

Mohamad Habes, Raymond Pomponio, Haochang Shou, Jimit Doshi, Elizabeth Mamourian, Guray Erus, Ilya Nasrallah, Lenore J Launer, Tanweer Rashid, Murat Bilgel, Yong Fan, Jon B Toledo, Kristine Yaffe, Aristeidis Sotiras, Dhivya Srinivasan, Mark Espeland, Colin Masters, Paul Maruff, Jurgen Fripp, Henry Völzk, et al.

Journal article  |  2021  |  Alzheimer's & Dementia

INTRODUCTION: Relationships between brain atrophy patterns of typical aging and Alzheimer's disease (AD), white matter disease, co..

Deferiprone to delay dementia (the 3D trial)

Scott Ayton, Michael Woodward, Kathryn A Ellis, Yen Ying Lim, Paul T Maruff, Patricia M Desmond, Olivier Salvado, Amir Fazlollahi, Christopher C Rowe, Leonid Churilov, Ashley I Bush

Journal article  |  2020  |  Alzheimer's & Dementia

Acceptability and Usability of Computerized Cognitive Assessment Among Australian Indigenous Residents of the Torres Strait Islands

Fintan Thompson, Lucette A Cysique, Linton R Harriss, Sean Taylor, Greg Savage, Paul Maruff, Robyn Mcdermott

Journal article  |  2020  |  Archives of Clinical Neuropsychology

OBJECTIVES: This cross-sectional study aimed to investigate the acceptability and usability of the Cogstate Brief Battery (CBB) in..

Phase 1 randomized study on the safety, tolerability, and pharmacodynamic cognitive and electrophysiological effects of a dopamine D-1 receptor positive allosteric modulator in patients with schizophrenia

Amit Desai, Lauren Benner, Ruishan Wu, Lev Gertsik, Paul Maruff, Gregory A Light, Tolga Uz, Gerard J Marek, Tong Zhu

Journal article  |  2020  |  Neuropsychopharmacology

ASP4345, a novel dopamine D1 receptor positive allosteric modulator, is being evaluated for the treatment of cognitive impairment ..

Association of deficits in short-term learning and A beta and hippocampal volume in cognitively normal adults

Yen Ying Lim, Jenalle E Baker, Loren Bruns, Andrea Mills, Christopher Fowler, Jurgen Fripp, Stephanie R Rainey-Smith, David Ames, Colin L Masters, Paul Maruff

Journal article  |  2020  |  Neurology

OBJECTIVE: To determine the extent to which deficits in learning over 6 days are associated with β-amyloid-positive (Aβ+) and hipp..