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Prof

Seong Tan

Honorary
Anatomy and Physiology
science & technology
life sciences & biomedicine
animals
mice
neurosciences
neurosciences & neurology
neurons
mice, inbred c57bl
humans
Seong Tan's Profile Picture
Prof

Seong Tan

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Brain Injury
Seong Tan's Profile Picture
Prof

Seong Tan

 
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Seong's  Short Profile
 

Projects

Displaying the 10 most recent projects by Seong Tan.

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UNDERSTANDING THE MECHANISMS OF PTEN TRANSFER INTO GLIAL CELLS USING EXOSOMES

This application will develop a new way of treating brain cancer which currently affects 1500 adults in Australia per year with no lasting c..

2015 - 2018
Completed
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THE REGULATION OF IRON TRANSPORT IN PARKINSON'S DISEASE

Currently there is no cure for Parkinson's disease, and although we have a number of treatments to manage the disease there is an urgent nee..

2014 - 2016
Completed
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THE ROLE OF PTEN TRAFFICKING IN NORMAL AND ABNORMAL CORTICAL DEVELOPMENT

Autism is a complex neurodevelopmental disorder that is estimated to affect 1 in every 100 children. Currently we have no medical treatments..

2014 - 2016
Completed
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GENES IMPORTANT FOR EARLY BRAIN DEVELOPMENT ARE ALSO IMPORTANT FOR ADULT BRAIN DISEASE

I committed to understanding of how the brain develops, grows and regenerates. My laboratory is active in finding a cure for brain injury fo..

2013 - 2017
Completed
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Saving brain cells from death after brain injury

We have discovered a new protein (Ndfip1) that protects brain cells from death after brain injury from trauma and stroke. We will investigat..

2012 - 2014
Completed
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DEVELOPMENT AND REFINEMENT OF NEURAL CONNECTIONS IN THE ADULT BRAIN IN HEALTH AND DISEASE

Our group will use innovative approaches such as advanced imaging and cell-sorting and development of animal models to determine how new neu..

2009 - 2013
Completed
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DEVELOPMENT AND REFINEMENT OF NEURAL CONNECTIONS IN THE ADULT BRAIN IN HEALTH AND DISEASE

Our group will use innovative approaches such as advanced imaging and cell-sorting and development of animal models to determine how new neu..

2009 - 2013
Completed
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Protecting neurons from death following brain injury

Brain injury from trauma and motor vehicle accidents is a serious health issue, affecting approximately 30,000 Australians per year. About 1..

2009 - 2011
Completed
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NHMRC RESEARCH FELLOWSHIP

I am a developmental neurobiologist interested in finding out how neurons in the brain are assembled and wired together. I am also intereste..

2008 - 2012
Completed
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Reelin function during cortical development

Disorders that occur during brain development can lead to abnormal behaviours traits such as anxiety and altered social interactions, plus a..

2007 - 2009
Completed

15

Projects

Project Types

13

Research Grant

2

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works by Seong Tan.

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Transcriptome analysis of ankylosed primary molars with infraocclusion

Annie Tong, Yuh-Lit Chow, Katie Xu, Rita Hardiman, Paul Schneider, Seong-Seng Tan

Journal article  |  2020  |  International Journal of Oral Science

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Ubiquitin Regulation of Trk Receptor Trafficking and Degradation

SS Murray, AW Wong, J Yang, Y Li, U Putz, S-S Tan, J Howitt

Journal article  |  2019  |  Molecular Neurobiology

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The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8( ) T Cell Tolerance Checkpoint to High-Dose Antigen

Mayura Wagle, Julia M Marchingo, Jason Howitt, Seong-Seng Tan, Christopher C Goodnow, Ian A Parish

Journal article  |  2018  |  Cell Reports

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A method for isolating cortical interneurons sharing the same birthdays for gene expression studies

Hui Xuan Ng, Ean Phing Lee, Brenton L Cavanagh, Joanne M Britto, Seong-Seng Tan

Journal article  |  2017  |  Experimental Neurology

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Engineered Exosomes as Vehicles for Biologically Active Proteins

Ulrich Sterzenbach, Ulrich Putz, Ley-Hian Low, John Silke, Seong-Seng Tan, Jason Howitt

Journal article  |  2017  |  Molecular Therapy

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Cortical Layer Inversion and Deregulation of Reelin Signaling in the Absence of SOCS6 and SOCS7

Isobel D Lawrenson, Danielle L Krebs, Edmond M Linossi, Jian-Guo Zhang, Tamara J McLennan, Caitlin Collin, Helen M Mcrae, Tatiana B Kolesnik, Katrina Koh, Joanne M Britto, Andrew J Kueh, Bilal N Sheikh, Farrah El-Saafin, Nicos A Nicola, Seong-Seng Tan, Jeffrey J Babon, Sandra E Nicholson, Warren S Alexander, Tim Thomas, Anne K Voss

Journal article  |  2017  |  Cerebral Cortex

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The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome

Shan Shan Li, Zhengdong Qu, Matilda Haas, Ngo Linh, You Jeong Heo, Hyo Jung Kang, Joanne Maria Britto, Hayley Daniella Cullen, Hannah Kate Vanyai, Seong-Seng Tan, Tailoi Chan-Ling, Jenny Margaret Gunnersen, Julian Ik-Tsen Heng

Journal article  |  2016  |  SCIENTIFIC REPORTS

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An aesthetic approach towards the temporary restoration of missing upper lateral incisors during orthodontic treatment

Katie Xu, Seong-Seng Tan

Journal article  |  2015  |  Australian Orthodontic Journal

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PTEN secretion in exosomes

Ulrich Putz, Sophia Mah, Choo-Peng Goh, Ley-Hian Low, Jason Howitt, Seong-Seng Tan

Journal article  |  2015  |  Methods

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Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity

Jason Howitt, Ley-Hian Low, Ulrich Putz, Anh Doan, Jenny Lackovic, Choo-Peng Goh, Jenny Gunnersen, John Silke, Seong-Seng Tan

Journal article  |  2015  |  Journal of Molecular Cell Biology

90

Scholarly Works

Keyword Analysis

Neurosciences
Clinical (organs, Diseases and Abnormal Conditions)
Clinical Health (organs, Diseases and Abnormal Conditions)
Biochemistry and Cell Biology
Expanding Knowledge
Genetics
Public Health
Clinical Sciences
Non-Oriented Research
Inorganic Chemistry

Honours, Awards and Fellowships

2004

FRACDS - Fellow of the Royal Australian College of Dental Surgeons

1

Award

Credentials

Positions

Honorary

Anatomy and Physiology

Honorary

Medicine - Royal Melbourne Hospital

Education

Master of Dental Science

Adelaide University

Bachelor of Dental Science

Institution not known

Doctor of Philosophy

University of Oxford