Colin Masters

Assessment of the DTI-ALPS Parameter Along the Perivascular Space in Older Adults at Risk of Dementia.

Christopher E Steward, Vijay K Venkatraman, Elaine Lui, Charles B Malpas, Kathryn A Ellis, Elizabeth V Cyarto, Lucy Vivash, Terence J O'Brien, Dennis Velakoulis, David Ames, Colin L Masters, Nicola T Lautenschlager, Roland Bammer, Patricia M Desmond

Journal article  |  2021  |  Journal of Neuroimaging

BACKGROUND AND PURPOSE: Recently, there has been growing interest in the glymphatic system (the functional waste clearance pathway..

Association of β-Amyloid Level, Clinical Progression, and Longitudinal Cognitive Change in Normal Older Individuals.

Laura M van der Kall, Thanh Truong, Samantha C Burnham, Vincent Doré, Rachel S Mulligan, Svetlana Bozinovski, Fiona Lamb, Pierrick Bourgeat, Jurgen Fripp, Stephanie Schultz, Yen Y Lim, Simon M Laws, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Paul Maruff, Colin L Masters, et al.

Journal article  |  2021  |  Neurology

OBJECTIVE: To determine the effect of β-amyloid (Aβ) level on progression risk to mild cognitive impairment (MCI) or dementia and ..

Aggregation of Abnormal Memory Scores and Risk of Incident Alzheimer's Disease Dementia: A Measure of Objective Memory Impairment in Amnestic Mild Cognitive Impairment.

Nicholas I Bradfield, Kathryn A Ellis, Greg Savage, Paul Maruff, Samantha Burnham, David Darby, Nicola T Lautenschlager, Ralph N Martins, Colin L Masters, Stephanie R Rainey-Smith, Joanne Robertson, Christopher Rowe, Michael Woodward, David Ames

Journal article  |  2021  |  Journal of the International Neuropsychological Society

OBJECTIVES: The criteria for objective memory impairment in mild cognitive impairment (MCI) are vaguely defined. Aggregating the n..

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Goate, Celeste M Karch, Anne M Fagan, Eric McDade, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Marc Suárez-Calvet, et al.

Journal article  |  2021  |  Molecular Psychiatry

In Alzheimer's disease (AD), a single-nucleotide polymorphism in the gene encoding brain-derived neurotrophic factor (BDNFVal66Met..

Non-negative matrix factorisation improves Centiloid robustness in longitudinal studies

Pierrick Bourgeat, Vincent Dore, James Doecke, David Ames, Colin L Masters, Christopher C Rowe, Jurgen Fripp, Victor L Villemagne

Journal article  |  2021  |  NeuroImage

BACKGROUND: Centiloid was introduced to harmonise β-Amyloid (Aβ) PET quantification across different tracers, scanners and analysi..

Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.

James M Roe, Didac Vidal-Piñeiro, Øystein Sørensen, Andreas M Brandmaier, Sandra Düzel, Hector A Gonzalez, Rogier A Kievit, Ethan Knights, Simone Kühn, Ulman Lindenberger, Athanasia M Mowinckel, Lars Nyberg, Denise C Park, Sara Pudas, Melissa M Rundle, Kristine B Walhovd, Anders M Fjell, René Westerhausen, undefined Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing

Journal article  |  2021  |  Nature Communications

Aging and Alzheimer's disease (AD) are associated with progressive brain disorganization. Although structural asymmetry is an orga..

Relationship between amyloid and tau levels and its impact on tau spreading

Vincent Dore, Natasha Krishnadas, Pierrick Bourgeat, Kun Huang, Shenpeng Li, Samantha Burnham, Colin L Masters, Jurgen Fripp, Victor L Villemagne, Christopher C Rowe

Journal article  |  2021  |  European Journal of Nuclear Medicine and Molecular Imaging

PURPOSE: Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, ..

Modeling autosomal dominant Alzheimer's disease with machine learning.

Patrick H Luckett, Austin McCullough, Brian A Gordon, Jeremy Strain, Shaney Flores, Aylin Dincer, John McCarthy, Todd Kuffner, Ari Stern, Karin L Meeker, Sarah B Berman, Jasmeer P Chhatwal, Carlos Cruchaga, Anne M Fagan, Martin R Farlow, Nick C Fox, Mathias Jucker, Johannes Levin, Colin L Masters, Hiroshi Mori, et al.

Journal article  |  2021  |  Alzheimer's & Dementia

INTRODUCTION: Machine learning models were used to discover novel disease trajectories for autosomal dominant Alzheimer's disease...

BDNF VAL66MET polymorphism and memory decline across the spectrum of Alzheimer's disease

Yen Ying Lim, Simon M Laws, Stephanie Perin, Robert H Pietrzak, Christopher Fowler, Colin L Masters, Paul Maruff

Journal article  |  2021  |  Genes Brain & Behavior

The brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism has been shown to moderate the extent to which memory ..

The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans.

Mohamad Habes, Raymond Pomponio, Haochang Shou, Jimit Doshi, Elizabeth Mamourian, Guray Erus, Ilya Nasrallah, Lenore J Launer, Tanweer Rashid, Murat Bilgel, Yong Fan, Jon B Toledo, Kristine Yaffe, Aristeidis Sotiras, Dhivya Srinivasan, Mark Espeland, Colin Masters, Paul Maruff, Jurgen Fripp, Henry Völzk, et al.

Journal article  |  2021  |  Alzheimer's & Dementia

INTRODUCTION: Relationships between brain atrophy patterns of typical aging and Alzheimer's disease (AD), white matter disease, co..