Georgina Such

Engineered Polymeric Materials for Biological Applications: Overcoming Challenges of the Bio-Nano Interface

Joshua D Simpson, Samuel A Smith, Kristofer J Thurecht, Georgina Such

Journal article  |  2019  |  Polymers

pH-Responsive Polymer Nanoparticles for Drug Delivery

Nayeleh Deirram, Changhe Zhang, Sarah S Kermaniyan, Angus PR Johnston, Georgina K Such

Journal article  |  2019  |  Macromolecular Rapid Communications

The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery

Samuel A Smith, Laura I Selby, Angus PR Johnston, Georgina K Such

Journal article  |  2019  |  Bioconjugate Chemistry

Controlling endosomal escape using nanoparticle composition: current progress and future perspectives

Kristofer I Cupic, Joshua J Rennick, Angus PR Johnston, Georgina K Such

Journal article  |  2019  |  Nanomedicine

Understanding Cell Interactions Using Modular Nanoparticle Libraries

Georgina K Such, Angus PR Johnston

Journal article  |  2019  |  Australian Journal of Chemistry

Controlling Endosomal Escape Using pH-Responsive Nanoparticles with Tunable Disassembly

Nachnicha Kongkatigumjorn, Samuel A Smith, Moore Chen, Katie Fang, Shenglin Yang, Elizabeth R Gillies, Angus PR Johnston, Georgina K Such

Journal article  |  2018  |  ACS Applied Nano Materials

The potential of nanoparticle vaccines as a treatment for cancer

David Urbanavicius, Tara Alvarez, Georgina K Such, Angus PR Johnston, Justine D Mintern

Journal article  |  2018  |  Molecular Immunology

Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles

Laura I Selby, Christina M Cortez-Jugo, Georgina K Such, Angus PR Johnston

Journal article  |  2017  |  Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Probing Endosomal Escape Using pHlexi Nanoparticles

Nachnicha Kongkatigumjorn, Christina Cortez-Jugo, Ewa Czuba, Adelene SM Wong, Rebecca Y Hodgetts, Angus PR Johnston, Georgina K Such

Journal article  |  2017  |  Macromolecular Bioscience

pH-Responsive Transferrin-pHlexi Particles Capable of Targeting Cells in Vitro

Adelene SM Wong, Ewa Czuba, Moore Z Chen, Daniel Yuen, Kristofer I Cupic, Shenglin Yang, Rebecca Y Hodgetts, Laura I Selby, Angus PR Johnston, Georgina K Such

Journal article  |  2017  |  ACS Macro Letters

Limitations with solvent exchange methods for synthesis of colloidal fullerenes

Shenglin Yang, Xavier Mulet, Thomas Gengenbach, Lynne Waddington, Aaron Seeber, Mingming Zhen, Chunru Wang, Benjamin W Muir, Georgina K Such, Xiaojuan Hao

Journal article  |  2017  |  Colloids and Surfaces A: Physicochemical and Engineering Aspects

Quantifying Nanoparticle Internalization Using a High Throughput Internalization Assay

Sarah K Mann, Ewa Czuba, Laura I Selby, Georgina K Such, Angus PR Johnston

Journal article  |  2016  |  Pharmaceutical Research

Flow Cytometry: HD Flow Cytometry: An Improved Way to Quantify Cellular Interactions with Nanoparticles (Adv. Healthcare Mater. 18/2016)

LI Selby, N Kongkatigumjorn, GK Such, APR Johnston

Journal article  |  2016  |  Advanced Healthcare Materials

HD Flow Cytometry: An Improved Way to Quantify Cellular Interactions with Nanoparticles

Laura I Selby, Nachnicha Kongkatigumjorn, Georgina K Such, Angus PR Johnston

Journal article  |  2016  |  Advanced Healthcare Materials

Phlexiparticles: Flexing the power of pH to escape the endosome

Georgina Such, Adelene Wong, Nachnicha Kongkatigumjorn, Katie Fang, Ewa Czuba, Angus Johnston

Conference Proceedings  |  2016  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Tuning the properties of pH responsive nanoparticles to control cellular interactions in vitro and ex vivo

SK Mann, A Dufour, JJ Glass, R De Rose, SJ Kent, GK Such, APR Johnston

Journal article  |  2016  |  Polymer Chemistry

Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets

Sylvia T Gunawan, Kristian Kempe, Thomas Bonnard, Jiwei Cui, Karen Alt, Lok S Law, Xiaowei Wang, Erik Westein, Georgina K Such, Karlheinz Peter, Christoph E Hagemeyer, Frank Caruso

Journal article  |  2015  |  Advanced Materials

Interfacing Materials Science and Biology for Drug Carrier Design

Georgina K Such, Yan Yan, Angus PR Johnston, Sylvia T Gunawan, Frank Caruso

Journal article  |  2015  |  Advanced Materials

Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use

Christoph E Hagemeyer, Karen Alt, Angus PR Johnston, Georgina K Such, Hang T Ta, Melissa KM Leung, Sandeep Prabhu, Xiaowei Wang, Frank Caruso, Karlheinz Peter

Journal article  |  2015  |  Nature Protocols

Self-assembling dual component nanoparticles with endosomal escape capability

Adelene SM Wong, Sarah K Mann, Ewa Czuba, Audrey Sahut, Haiyin Liu, Tiffany C Suekama, Tayla Bickerton, Angus PR Johnston, Georgina K Such

Journal article  |  2015  |  Soft Matter

Tuning Particle Biodegradation through Polymer-Peptide Blend Composition

Sylvia T Gunawan, Kristian Kempe, Georgina K Such, Jiwei Cui, Kang Liang, Joseph J Richardson, Angus PR Johnston, Frank Caruso

Journal article  |  2014  |  Biomacromolecules

Engineering Enzyme-Cleavable Hybrid Click Capsules with a pH-Sheddable Coating for Intracellular Degradation

Sylvia T Gunawan, Kang Liang, Georgina K Such, Angus PR Johnston, Melissa KM Leung, Jiwei Cui, Frank Caruso

Journal article  |  2014  |  Small

Endocytic Capsule Sensors for Probing Cellular Internalization

Kang Liang, Sylvia T Gunawan, Joseph J Richardson, Georgina K Such, Jiwei Cui, Frank Caruso

Journal article  |  2014  |  Advanced Healthcare Materials

Fundamental Studies of Hybrid Poly(2-(diisopropylamino)ethyl methacrylate)/Poly(N-vinylpyrrolidone) Films and Capsules

Sher Leen Ng, James P Best, Kristian Kempe, Kang Liang, Angus PR Johnston, Georgina K Such, Frank Caruso

Journal article  |  2014  |  Biomacromolecules

Peptide-Tunable Drug Cytotoxicity via One-Step Assembled Polymer Nanoparticles

Kang Liang, Joseph J Richardson, Hirotaka Ejima, Georgina K Such, Jiwei Cui, Frank Caruso

Journal article  |  2014  |  Advanced Materials

Endocytic pH-Triggered Degradation of Nanoengineered Multilayer Capsules

Kang Liang, Georgina K Such, Angus PR Johnston, Zhiyuan Zhu, Hirotaka Ejima, Joseph J Richardson, Jiwei Cui, Frank Caruso

Journal article  |  2014  |  Advanced Materials

One-Step Assembly of Coordination Complexes for Versatile Film and Particle Engineering

Hirotaka Ejima, Joseph J Richardson, Kang Liang, James P Best, Martin P van Koeverden, Georgina K Such, Jiwei Cui, Frank Caruso

Journal article  |  2013  |  Science

Mechanically Tunable, Self-Adjuvanting Nanoengineered Polypeptide Particles

Jiwei Cui, Robert De Rose, James P Best, Angus PR Johnston, Sheilajen Alcantara, Kang Liang, Georgina K Such, Stephen J Kent, Frank Caruso

Journal article  |  2013  |  Advanced Materials

Design of Degradable Click Delivery Systems

Georgina K Such, Sylvia T Gunawan, Kang Liang, Frank Caruso

Journal article  |  2013  |  Macromolecular Rapid Communications

Engineering Cellular Degradation of Multilayered Capsules through Controlled Cross-Linking

Kang Liang, Georgina K Such, Zhiyuan Zhu, Sarah J Dodds, Angus PR Johnston, Jiwei Cui, Hirotaka Ejima, Frank Caruso

Journal article  |  2012  |  ACS Nano

Targeted drug delivery: Understanding cellular binding and uptake of nanoengineered capsules

Angus PR Johnston, Georgina K Such, Marloes Kamphuis, Frank Caruso

Conference Proceedings  |  2012  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Click poly(ethylene glycol) multilayers on RO membranes: Fouling reduction and membrane characterization

Cheli Wang, Georgina K Such, Adrian Widjaya, Hannah Lomas, Geoff Stevens, Frank Caruso, Sandra E Kentish

Journal article  |  2012  |  Journal of Membrane Science

Immobilization and Intracellular Delivery of an Anticancer Drug Using Mussel-Inspired Polydopamine Capsules

Jiwei Cui, Yan Yan, Georgina K Such, Kang Liang, Christopher J Ochs, Almar Postma, Frank Caruso

Journal article  |  2012  |  Biomacromolecules

Targeting Cancer Cells: Controlling the Binding and Internalization of Antibody-Functionalized Capsules

Angus PR Johnston, Marloes MJ Kamphuis, Georgina K Such, Andrew M Scott, Edouard C Nice, Joan K Heath, Frank Caruso

Journal article  |  2012  |  ACS Nano

Synthesis and functionalization of nanoengineered materials using click chemistry

Georgina K Such, Angus PR Johnston, Kang Liang, Frank Caruso

Journal article  |  2012  |  Progress in Polymer Science: an international review journal

Engineered Layer-by-Layer Assembled Capsules for Biomedical Applications

APR Johnston, GK Such, SJ Dodds, F Caruso

Book Chapter  |  2012

Engineering Particles for Therapeutic Delivery: Prospects and Challenges

Yan Yan, Georgina K Such, Angus PR Johnston, James P Best, Frank Caruso

Journal article  |  2012  |  ACS Nano

Photoinitiated Alkyne-Azide Click and Radical Cross-Linking Reactions for the Patterning of PEG Hydrogels

Rodney T Chen, Silvia Marchesan, Richard A Evans, Katie E Styan, Georgina K Such, Almar Postma, Keith M McLean, Benjamin W Muir, Frank Caruso

Journal article  |  2012  |  Biomacromolecules

Bio-Click Chemistry: Enzymatic Functionalization of PEGylated Capsules for Targeting Applications

Melissa KM Leung, Christoph E Hagemeyer, Angus PR Johnston, Catalina Gonzales, Marloes MJ Kamphuis, Katie Ardipradja, Georgina K Such, Karlheinz Peter, Frank Caruso

Journal article  |  2012  |  Angewandte Chemie - International Edition

Nanoengineered Films via Surface-Confined Continuous Assembly of Polymers

Tor Kit Goh, Stefanie N Guntari, Christopher J Ochs, Anton Blencowe, Damien Mertz, Luke A Connal, Georgina K Such, Greg G Qiao, Frank Caruso

Journal article  |  2011  |  Small

Charge-Shifting Click Capsules with Dual-Responsive Cargo Release Mechanisms

Kang Liang, Georgina K Such, Zhiyuan Zhu, Yan Yan, Hannah Lomas, Frank Caruso

Journal article  |  2011  |  Advanced Materials

Controlled release of DNA from poly(vinylpyrrolidone) capsules using cleavable linkers

Sher Leen Ng, Georgina K Such, Angus PR Johnston, Gema Antequera-Garcia, Frank Caruso

Journal article  |  2011  |  Biomaterials

Polymersome-Loaded Capsules for Controlled Release of DNA

Hannah Lomas, Angus PR Johnston, Georgina K Such, Zhiyuan Zhu, Kang Liang, Martin P van Koeverden, Siripong Alongkornchotikul, Frank Caruso

Journal article  |  2011  |  Small

Dopamine-Mediated Continuous Assembly of Biodegradable Capsules

Christopher J Ochs, Tam Hong, Georgina K Such, Jiwei Cui, Almar Postma, Frank Caruso

Journal article  |  2011  |  Chemistry of Materials

Challenges facing colloidal delivery systems: From synthesis to the clinic

Angus PR Johnston, Georgina K Such, Sher Leen Ng, Frank Caruso

Journal article  |  2011  |  Current Opinion in Colloid & Interface Science

Toward Therapeutic Delivery with Layer-by-Layer Engineered Particles

Yan Yan, Georgina K Such, Angus PR Johnston, Hannah Lomas, Frank Caruso

Journal article  |  2011  |  ACS Nano

New Insights into the Substrate-Plasma Polymer Interface

Rodney T Chen, Benjamin W Muir, Lars Thomsen, Anton Tadich, Bruce CC Cowie, Georgina K Such, Almar Postma, Keith M McLean, Frank Caruso

Journal article  |  2011  |  Journal of Physical Chemistry B

Assembly and Degradation of Low-Fouling Click-Functionalized Poly(ethylene glycol)-Based Multilayer Films and Capsules

Melissa KM Leung, Georgina K Such, Angus PR Johnston, Dhee P Biswas, Zhiyuan Zhu, Yan Yan, Jean-Francois Lutz, Frank Caruso

Journal article  |  2011  |  Small

Tuning the Properties of Layer-by-Layer Assembled Poly(acrylic acid) Click Films and Capsules

Cameron R Kinnane, Georgina K Such, Frank Caruso

Journal article  |  2011  |  Macromolecules

Modular Assembly of Layer-by-Layer Capsules with Tailored Degradation Profiles

Christopher J Ochs, Georgina K Such, Frank Caruso

Journal article  |  2011  |  Langmuir

ATRP-mediated continuous assembly of polymers for the preparation of nanoscale films

Damien Mertz, Christopher J Ochs, Zhiyuan Zhu, Lillian Lee, Stefanie N Guntari, Georgina K Such, Tor Kit Goh, Luke A Connal, Anton Blencowe, Greg G Qiao, Frank Caruso

Journal article  |  2011  |  Chemical Communications

Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications

Georgina K Such, Angus PR Johnston, Frank Caruso

Journal article  |  2011  |  Chemical Society Reviews

Layer-by-Layer Assembled Capsules for Biomedical Applications

GK Such, APR Johnston, F Caruso

Book Chapter  |  2011

Bypassing Multidrug Resistance in Cancer Cells with Biodegradable Polymer Capsules

Yan Yan, Christopher J Ochs, Georgina K Such, Joan K Heath, Edouard C Nice, Frank Caruso

Journal article  |  2010  |  Advanced Materials

Targeting of Cancer Cells Using Click-Functionalized Polymer Capsules

Marloes MJ Kamphuis, Angus PR Johnston, Georgina K Such, Henk H Dam, Richard A Evans, Andrew M Scott, Edouard C Nice, Joan K Heath, Frank Caruso

Journal article  |  2010  |  Journal of the American Chemical Society

Surface "Click" Chemistry on Brominated Plasma Polymer Thin Films

Rodney T Chen, Benjamin W Muir, Georgina K Such, Almar Postma, Richard A Evans, Suzanne M Pereira, Keith M McLean, Frank Caruso

Journal article  |  2010  |  Langmuir

Biodegradable Click Capsules with Engineered Drug-Loaded Multilayers

Christopher J Ochs, Georgina K Such, Yan Yan, Martin P van Koeverden, Frank Caruso

Journal article  |  2010  |  ACS Nano

Reaction Vessels Assembled by the Sequential Adsorption of Polymers

Andrew D Price, Angus PR Johnston, Georgina K Such, Frank Caruso

Book Chapter  |  2010  |  Advances in Polymer Science

Fabrication of asymmetric "Janus'' particles via plasma polymerization

Rodney T Chen, Benjamin W Muir, Georgina K Such, Almar Postma, Keith M McLean, Frank Caruso

Journal article  |  2010  |  Chemical Communications

Triggering Release of Encapsulated Cargo

Angus PR Johnston, Georgina K Such, Frank Caruso

Journal article  |  2010  |  Angewandte Chemie - International Edition

Click-Engineered, Bioresponsive, Drug-Loaded PEG Spheres

Heng Pho Yap, Angus PR Johnston, Georgina K Such, Yan Yan, Frank Caruso

Journal article  |  2009  |  Advanced Materials

Low-Fouling Poly(N-vinyl pyrrolidone) Capsules with Engineered Degradable Properties

Cameron R Kinnane, Georgina K Such, Gema Antequera-Garcia, Yan Yan, Sarah J Dodds, Luis M Liz-Marzan, Frank Caruso

Journal article  |  2009  |  Biomacromolecules

Peptide-Functionalized, Low-Biofouling Click Multilayers for Promoting Cell Adhesion and Growth

Cameron R Kinnane, Kim Wark, Georgina K Such, Angus PR Johnston, Frank Caruso

Journal article  |  2009  |  Small

Low-Fouling, Biofunctionalized, and Biodegradable Click Capsules

Christopher J Ochs, Georgina K Such, Brigitte Staedler, Frank Caruso

Journal article  |  2008  |  Biomacromolecules

A click chemistry approach to nano-engineered thin films and particles

GK Such, CR Kinnane, CJ Ochs, APR Johnston, E Tjipto, A Postma, F Caruso

Conference Proceedings  |  2008  |  American Chemical Society, Polymer Preprints, Division of Polymer Chemistry

Polyelectrolyte blend multilayers: A versatile route to engineering interfaces and films

Anthony Quinn, Georgina K Such, John F Quinn, Frank Caruso

Journal article  |  2008  |  Advanced Functional Materials

Poly(vinylpyrrolidone) for bioconjugation and surface ligand immobilization

Alexander N Zelikin, Georgina K Such, Almar Postma, Frank Caruso

Journal article  |  2007  |  Biomacromolecules

COLL 299-Poly(vinylpyrrolidone) for bioconjugation and ligand immobilization

Alexander N Zelikin, Georgina K Such, Almar Postma, Frank Caruso

Journal article  |  2007  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Ultrathin, responsive polymer click capsules

Georgina K Such, Elvira Tjipto, Almar Postma, Angus PR Johnston, Frank Caruso

Journal article  |  2007  |  Nano Letters

Next generation, sequentially assembled ultrathin films: beyond electrostatics

John F Quinn, Angus PR Johnston, Georgina K Such, Alexander N Zelikin, Frank Caruso

Journal article  |  2007  |  Chemical Society Reviews

The use of block copolymers to systematically modify photochromic behavior

Georgina K Such, Richard A Evans, Thomas P Davis

Journal article  |  2006  |  Macromolecules

Assembly of ultrathin polymer multilayer films by click chemistry

Georgina K Such, John F Quinn, Anthony Quinn, Elvira Tjipto, Frank Caruso

Journal article  |  2006  |  Journal of the American Chemical Society

Rapid photochromic switching in a rigid polymer matrix using living radical polymerization

GK Such, RA Evans, TP Davis

Journal article  |  2006  |  Macromolecules

Rapid Photochromic Switching in a Rigid Polymer Matrix Using Living Radical Polymerization

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Journal article  |  2006  |  Macromolecules

The generic enhancement of photochromic dye switching speeds in a rigid polymer matrix

RA Evans, TL Hanley, MA Skidmore, TP Davis, GK Such, LH Yee, GE Ball, DA Lewis

Journal article  |  2005  |  Nature Materials

Tailoring photochromic performance of polymer-dye conjugates using living radical polymerization (ATRP)

GK Such, RA Evans, TP Davis

Journal article  |  2005  |  Molecular Crystals and Liquid Crystals

Research trends in photochromism: Control of photochromism in rigid polymer matrices and other advances

RA Evans, GK Such

Journal article  |  2005  |  Australian Journal of Chemistry

Control of photochromism through local environment effects using living radical polymerization (ATRP)

GK Such, RA Evans, TP Davis

Journal article  |  2004  |  Macromolecules

Factors influencing photochromism of spiro-compounds within polymeric matrices

G Such, RA Evans, LH Yee, TP Davis

Journal article  |  2003  |  Journal of Macromolecular Science, Part C: Polymer Reviews