Robert Bischof

Umbilical cord blood versus mesenchymal stem cells for inflammation-induced preterm brain injury in fetal sheep

Madison CB Paton, Beth J Allison, Michael C Fahey, Jingang Li, Amy E Sutherland, Yen Pham, Ilias Nitsos, Robert J Bischof, Timothy J Moss, Graeme R Polglase, Graham Jenkin, Suzanne L Miller, Courtney A McDonald

Journal article  |  2019  |  PEDIATRIC RESEARCH

BACKGROUND: Chorioamnionitis and fetal inflammation are principal causes of neuropathology detected after birth, particularly in v..

Human Umbilical Cord Blood Therapy Protects Cerebral White Matter from Systemic LPS Exposure in Preterm Fetal Sheep

Madison CB Paton, Beth J Allison, Jingang Li, Michael C Fahey, Amy E Sutherland, Ilias Nitsos, Robert J Bischof, Justin M Dean, Timothy JM Moss, Graeme R Polglase, Graham Jenkin, Courtney A McDonald, Suzanne L Miller

Journal article  |  2018  |  DEVELOPMENTAL NEUROSCIENCE

BACKGROUND: Infants born preterm following exposure to in utero inflammation/chorioamnionitis are at high risk of brain injury and..

Development of an experimental model of maternal allergic asthma during pregnancy.

Vicki L Clifton, Timothy JM Moss, Amy L Wooldridge, Kathryn L Gatford, Bahar Liravi, Dasom Kim, Beverly S Muhlhausler, Janna L Morrison, Andrew Davies, Robert De Matteo, Megan J Wallace, Robert J Bischof

Journal article  |  2016  |  J Physiol

Maternal asthma during pregnancy adversely affects pregnancy outcomes but identification of the cause/s, and the ability to evalua..

Postprandial heat production in skeletal muscle is associated with altered mitochondrial function and altered futile calcium cycling

Scott D Clarke, Kevin Lee, Zane B Andrews, Robert Bischof, Fahri Fahri, Roger G Evans, Iain J Clarke, Belinda A Henry

Journal article  |  2012  |  AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

This study aimed to determine whether postprandial temperature excursions in skeletal muscle are consistent with thermogenesis or ..

Sheep as a model species for the study and treatment of human asthma and other respiratory diseases

EN Meeusen, KJ Snibson, SJ Hirst, RJ Bischof

Journal article  |  2009  |  Drug Discovery Today: Disease Models

Classic studies in sheep have contributed greatly to our understanding of lung physiology in health and disease. Similarities in s..

Chronic airway disease: Deteriorating pulmonary function in sheep associated with repeated challenges of house dust mite

Emmanuel Koumoundouros, Robert J Bischof, Els N Meeusen, Iven MY Mareels, Kenneth J Snibson

Journal article  |  2006  |  EXPERIMENTAL LUNG RESEARCH

The aim of this work was to characterize lung function and cellular responses in a large animal model for chronic asthma. All shee..

Altered airway responsiveness in adult sheep born prematurely: Effects of allergen exposure

Kenneth J Snibson, Robert J Bischof, Emmanuel Koumoundouros, Lachlan S McMurtrie, Megan Cock, Richard Harding

Journal article  |  2006  |  EXPERIMENTAL LUNG RESEARCH

The aim of this study was to determine the effects of preterm birth per se on airway function in adult sheep. Preterm birth was in..

Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite

KJ Snibson, RJ Bischof, RF Slocombe, EN Meeusen

Journal article  |  2005  |  CLINICAL AND EXPERIMENTAL ALLERGY

BACKGROUND: Remodelling of airway walls is a significant morbidity factor in patients suffering from chronic asthma. The relations..

Induction of allergic inflammation in the lungs of sensitized sheep after local challenge with house dust mite

RJ Bischof, K Snibson, R Shaw, ENT Meeusen

Journal article  |  2003  |  CLINICAL AND EXPERIMENTAL ALLERGY

BACKGROUND: Previous sheep models of asthma are based on sheep sensitized to nematode (Ascaris) allergens and these have been used..

Phagocytic capacity of leucocytes in sheep mammary secretions following weaning

L Tatarczuch, RJ Bischof, CJ Philip, CS Lee

Journal article  |  2002  |  JOURNAL OF ANATOMY

Lactating animals are particularly susceptible to mastitis during the early stages of mammary gland involution following weaning. ..