Ellie Hyun-Jung Cho

Quantification of Golgi Entry and Exit Kinetics of Protein Cargoes.

Jingqi Wang, Ellie Hyun-Jung Cho, Paul A Gleeson, Lou Fourriere

Book Chapter  |  2023  |  Methods in Molecular Biology

The Golgi apparatus is a pivotal secretory organelle in membrane trafficking, a hub responsible for posttranslational modification..

Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains

Pei Wen Lee, Andrew C Marshall, Gavin J Knott, Simon Kobelke, Luciano Martelotto, Ellie Cho, Paul J McMillan, Mihwa Lee, Charles S Bond, Archa H Fox

Journal article  |  2022  |  JOURNAL OF BIOLOGICAL CHEMISTRY

RNA-binding proteins of the DBHS (Drosophila Behavior Human Splicing) family, NONO, SFPQ, and PSPC1 have numerous roles in genome ..

Repurposing the mitotic machinery to drive cellular elongation and chromatin reorganisation in Plasmodium falciparum gametocytes

Jiahong Li, Gerald J Shami, Ellie Cho, Boyin Liu, Eric Hanssen, Matthew WA Dixon, Leann Tilley

Journal article  |  2022  |  NATURE COMMUNICATIONS

The sexual stage gametocytes of the malaria parasite, Plasmodium falciparum, adopt a falciform (crescent) shape driven by the asse..

Interacting partners of Golgi-localized small G protein Arl5b identified by a combination of in vivo proximity labelling and GFP-Trap pull down

Fiona J Houghton, Christian Makhoul, Ellie Hyun-Jung Cho, Nicholas A Williamson, Paul A Gleeson

Journal article  |  2022  |  FEBS LETTERS

The small G protein Arl5b is localised on the trans-Golgi network (TGN) and regulates endosomes-to-TGN transport. Here, we combine..

Extracellular Vesicles Secreted by Glioma Stem Cells Are Involved in Radiation Resistance and Glioma Progression

Chenkai Ma, Hong PT Nguyen, Jordan J Jones, Stanley S Stylli, Clarissa A Whitehead, Lucy Paradiso, Rodney B Luwor, Zammam Areeb, Eric Hanssen, Ellie Cho, Ulrich Putz, Andrew H Kaye, Andrew P Morokoff

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glioblastoma is the most aggressive brain tumour with short survival, partly due to resistance to conventional therapy. Glioma ste..

Segregation of the membrane cargoes, BACE1 and amyloid precursor protein (APP) throughout the Golgi apparatus

Lou Fourriere, Ellie Hyun-Jung Cho, Paul A Gleeson

Journal article  |  2022  |  TRAFFIC

The intracellular trafficking of β-site amyloid precursor protein (APP) cleaving enzyme (BACE1) and APP regulates amyloid-β produc..

Longitudinal Monitoring of Intra-Tumoural Heterogeneity Using Optical Barcoding of Patient-Derived Colorectal Tumour Models

Carolyn Shembrey, Jai Smith, Melodie Grandin, Nathalia Williams, Hyun-Jung Cho, Christina Molck, Corina Behrenbruch, Benjamin NJ Thomson, Alexander G Heriot, Delphine Merino, Frederic Hollande

Journal article  |  2022  |  CANCERS

Geno- and phenotypic heterogeneity amongst cancer cell subpopulations are established drivers of treatment resistance and tumour r..

Coagulation factor-XII induces interleukin-6 by primary lung fibroblasts: a role in idiopathic pulmonary fibrosis?

Jade Jaffar, Laura McMillan, Nick Wilson, Con Panousis, Charles Hardy, Hyun-Jung Cho, Karen Symons, Ian Glaspole, Glen Westall, Mae Wong

Journal article  |  2022  |  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The mechanisms driving idiopathic pulmonary fibrosis (IPF) remain undefined, however it is postulated that coagulation imbalances ..

STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise- and Load-Induced Bone Formation

Narelle E McGregor, Emma C Walker, Audrey SM Chan, Ingrid J Poulton, Ellie H-J Cho, Sara H Windahl, Natalie A Sims

Journal article  |  2021  |  JOURNAL OF BONE AND MINERAL RESEARCH

Cortical bone develops and changes in response to mechanical load, which is sensed by bone-embedded osteocytes. The bone formation..

Visualising biodistribution and biokinetics of inhaled biologicals: application of light sheet imaging technology

Giuseppe Ciccotosto, Andrew Jarnicki, Robert O'Donoghue, Mun-Joo Chuei, Caitlin O'Brien, Gabriela Segal, Ellie Cho, Eva-Maria Hansbauer, Stefan Kling, Thomas Jaquin, Gabriele Matschiner, Shane Olwill, Gary P Anderson

Conference Proceedings  |  2021  |  EUROPEAN RESPIRATORY JOURNAL