Steven Collins

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2019.

Christiane Stehmann, Matteo Senesi, Shannon Sarros, Amelia McGlade, Marion Simpson, Genevieve Klug, Catriona McLean, Colin L Masters, Steven Collins

Journal article  |  2020  |  Communicable Diseases Intelligence

Nationwide surveillance of Creutzfeldt-Jakob disease and other human prion diseases is performed by the Australian National Creutz..

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December

Christiane Stehmann, Matteo Senesi, Shannon Sarros, Amelia McGlade, Marion Simpson, Genevieve Klug, Catriona McLean, Colin L Masters, Steven Collins

Journal article  |  2020  |  Communicable diseases intelligence quarterly report

Nation-wide surveillance of transmissible spongiform encephalopathies including Creutzfeldt-Jakob disease, is performed by the Aus..

Decreased cerebrospinal fluid neuronal pentraxin receptor is associated with PET-A beta load and cerebrospinal fluid A beta in a pilot study of Alzheimer's disease

Bryant Lim, Christopher Fowler, Qiao-Xin Li, Christopher Rowe, Kunal Dhiman, Veer Bala Gupta, Colin L Masters, James D Doecke, Ralph N Martins, Steven Collins, Eleftherios P Diamandis

Journal article  |  2020  |  Neuroscience Letters

Multifactorial pathological processes of Alzheimer's disease (AD) begin decades prior to clinical onset. Early identification of p..

PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity

Simote T Foliaki, Victoria Lewis, Abu MT Islam, Matteo Senesi, David Finkelstein, Laura J Ellett, Victoria A Lawson, Paul A Adlard, Blaine R Roberts, Steven J Collins

Journal article  |  2020  |  Biophysical Journal

Prion diseases are neurodegenerative disorders pathogenically linked to cellular prion protein (PrPC) misfolding into abnormal con..

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease

Sonia M Vallabh, Eric Vallabh Minikel, Victoria J Williams, Becky C Carlyle, Alison J McManus, Chase D Wennick, Anna Bolling, Bianca A Trombetta, David Urick, Chloe K Nobuhara, Jessica Gerber, Holly Duddy, Ingolf Lachmann, Christiane Stehmann, Steven J Collins, Kaj Blennow, Henrik Zetterberg, Steven E Arnold

Journal article  |  2020  |  BMC Medicine

BACKGROUND: Prion disease is neurodegenerative disease that is typically fatal within months of first symptoms. Clinical trials in..

The cellular prion protein beyond prion diseases.

Giorgia Manni, Victoria Lewis, Matteo Senesi, Giovanni Spagnolli, Francesca Fallarino, Steven J Collins, Sophie Mouillet-Richard, Emiliano Biasini

Journal article  |  2020  |  Swiss Medical Weekly

The cellular prion protein (PrPC), a cell surface glycoprotein originally identified for its central role in prion diseases (also ..

Prion disease in Indigenous Australians.

Peter K Panegyres, Christiane Stehmann, Genevieve M Klug, Colin L Masters, Steven Collins

Journal article  |  2020  |  Internal Medicine Journal

BACKGROUND: Indigenous Australians are of increased risk of developing dementia - Alzheimer's disease and mixed dementia diagnoses..

Elecsys CSF biomarker immunoassays demonstrate concordance with amyloid-PET imaging

James D Doecke, Larry Ward, Samantha C Burnham, Victor L Villemagne, Qiao-Xin Li, Steven Collins, Christopher J Fowler, Ekaterina Manuilova, Monika Widmann, Stephanie R Rainey-Smith, Ralph N Martins, Colin L Masters

Journal article  |  2020  |  Alzheimer's Research & Therapy

BACKGROUND: β-amyloid (Aβ) positron emission tomography (PET) imaging is currently the only Food and Drug Administration-approved ..

Lymphoma, a great imitator in neurology

Wei Zhen Yeh, Subramanian Muthusamy, Penny McKelvie, Steven Collins, Ann French, Robin Filshie, Tom Sutherland, Nicholas Trost, Katrina Reardon

Journal article  |  2020  |  Journal of Clinical Neuroscience

The title "great imitator" refers to conditions which can cause varied manifestations and mimic many diseases. Lymphoma is worthy ..

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

Franc Llorens, Anna Villar-Pique, Peter Hermann, Matthias Schmitz, Olga Calero, Christiane Stehmann, Shannon Sarros, Fabio Moda, Isidre Ferrer, Anna Poleggi, Maurizio Pocchiari, Marcella Catania, Sigrid Klotz, Carl O'Regan, Francesca Brett, Josephine Heffernan, Anna Ladogana, Steven J Collins, Miguel Calero, Gabor G Kovacs, et al.

Journal article  |  2020  |  Biomolecules

Human prion diseases are classified into sporadic, genetic, and acquired forms. Within this last group, iatrogenic Creutzfeldt-Jak..

A pilot study of the utility of cerebrospinal fluid neurofilament light chain in differentiating neurodegenerative from psychiatric disorders: A 'C-reactive protein' for psychiatrists and neurologists?

Dhamidhu Eratne, Samantha M Loi, Nirbaanjot Walia, Sarah Farrand, Qiao-Xin Li, Shiji Varghese, Mark Walterfang, Andrew Evans, Ramon Mocellin, Kunal Dhiman, Veer Gupta, Charles B Malpas, Steven Collins, Colin L Masters, Dennis Velakoulis

Journal article  |  2020  |  Australian & New Zealand Journal of Psychiatry

OBJECTIVE: Neurofilament light has shown promise as a biomarker for diagnosis, staging and prognosis in a wide range of neurologic..

Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease.

Kunal Dhiman, Veer Bala Gupta, Victor L Villemagne, Dhamidhu Eratne, Petra L Graham, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I Bush, Christopher C Rowe, Colin L Masters, David Ames, Eugene Hone, Kaj Blennow, Henrik Zetterberg, Ralph N Martins

Journal article  |  2020  |  Alzheimers Dement (Amst)

Introduction: This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) d..

Cerebrospinal fluid neurofilament light chain is elevated in Niemann-Pick type C compared to psychiatric disorders and healthy controls and may be a marker of treatment response

Dhamidhu Eratne, Samantha M Loi, Qiao-Xin Li, Shiji Varghese, Amelia McGlade, Steven Collins, Colin L Masters, Dennis Velakoulis, Mark Walterfang

Journal article  |  2019  |  Australian & New Zealand Journal of Psychiatry

A healthy dietary pattern associates with a lower risk of a first clinical diagnosis of central nervous system demyelination

Lucinda J Black, Charlotte Rowley, Jill Sherriff, Gavin Pereira, Anne-Louise Ponsonby, Robyn M Lucas, Jeffrey Blackie, Richard Bourke, John Cameron, Ross Carne, Ben Clark, Steven Collins, Diana Conrad, Michael Coroneos, Nicholas Downie, David Floate, Peter Gates, Kerryn Green, Erwin Groeneveld, John Harrison, et al.

Journal article  |  2019  |  Multiple Sclerosis Journal

Application of the NIA-AA Research Framework: Towards a Biological Definition of Alzheimer's Disease using Cerebrospinal Fluid Biomarkers in the AIBL Study

SC Burnham, PM Coloma, Q-X Li, S Collins, G Savage, S Laws, J Doecke, P Maruff, RN Martins, D Ames, CC Rowe, CL Masters, VL Villemagne

Journal article  |  2019  |  The journal of prevention of Alzheimer's disease

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2018

Christiane Stehmann, Matteo Senesi, Victoria Lewis, Mairin Ummi, Marion Simpson, Genevieve Klug, Catriona McLean, Colin Masters, Steven Collins

Journal article  |  2019  |  Communicable Diseases Intelligence

Creutzfeldt-Jakob disease surveillance in Australia: update to December 2017

Christiane Stehmann, Shannon Sarros, Matteo Senesi, Victoria Lewis, Marion Simpson, Catriona McLean, Colin Masters, Steven Collins

Journal article  |  2019  |  Communicable diseases intelligence (2018)

Creutzfeldt–Jakob disease surveillance in Australia: update to December 2017

Christiane Stehmann, Shannon Sarros, Matteo Senesi, Victoria Lewis, Marion Simpson, Catriona McLean, Colin Masters, Steven Collins

Journal article  |  2019  |  Communicable Diseases Intelligence

Nationwide surveillance of human prion diseases (also known as transmissible spongiform encephalopathies), the most common being C..

Age at onset in genetic prion disease and the design of preventive clinical trials

Eric Vallabh Minikel, Sonia M Vallabh, Margaret C Orseth, Jean-Philippe Brandel, Stephane Haik, Jean-Louis Laplanche, Inga Zerr, Piero Parchi, Sabina Capellari, Jiri Safar, Janna Kenny, Jamie C Fong, Leonel T Takada, Claudia Ponto, Peter Hermann, Tobias Knipper, Christiane Stehmann, Tetsuyuki Kitamoto, Ryusuke Ae, Tsuyoshi Hamaguchi, et al.

Journal article  |  2019  |  Neurology

OBJECTIVE: To determine whether preventive trials in genetic prion disease could be designed to follow presymptomatic mutation car..

ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes

Anja Soldan, Corinne Pettigrew, Anne M Fagan, Suzanne E Schindler, Abhay Moghekar, Christopher Fowler, Qiao-Xin Li, Steven J Collins, Cynthia Carlsson, Sanjay Asthana, Colin L Masters, Sterling Johnson, John C Morris, Marilyn Albert, Alden L Gross

Journal article  |  2019  |  Neurology

OBJECTIVE: To examine the long-term cognitive trajectories of individuals with normal cognition at baseline and distinct amyloid/t..

Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc

Simote Totauhelotu Foliaki, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A Lawson, Paul Anthony Adlard, Steven John Collins

Journal article  |  2019  |  PLOS Pathogens

Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases

Anna Villar-Pique, Matthias Schmitz, Ingolf Lachmann, Andre Karch, Olga Calero, Christiane Stehmann, Shannon Sarros, Anna Ladogana, Anna Poleggi, Isabel Santana, Isidre Ferrer, Eva Mitrova, Dana Zakova, Maurizio Pocchiari, Ines Baldeiras, Miguel Calero, Steven J Collins, Michael D Geschwind, Raquel Sanchez-Valle, Inga Zerr, et al.

Journal article  |  2019  |  Molecular Neurobiology

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

Adrian P Wiegmans, Jodi M Saunus, Sunyoung Ham, Richard Lobb, Jamie R Kutasovic, Andrew J Dalley, Mariska Miranda, Caroline Atkinson, Simote T Foliaki, Kaltin Ferguson, Colleen Niland, Cameron N Johnstone, Victoria Lewis, Steven J Collins, Sunil R Lakhani, Fares Al-Ejeh, Andreas Moller

Journal article  |  2019  |  JCI Insight

Comparative Utility of Manual versus Automated Segmentation of Hippocampus and Entorhinal Cortex Volumes in a Memory Clinic Sample

Yi Leng Fung, Kelly ET Ng, Simon J Vogrin, Catherine Meade, Michael Ngo, Steven J Collins, Stephen C Bowden

Journal article  |  2019  |  Journal of Alzheimer's Disease

"To Treat or not To Treat": Informing the Decision for Disease-Modifying Therapy in Late-Stage Alzheimer's Disease

Andrew D Watt, Nicole L Jenkins, Gawain McColl, Steven Collins, Patricia M Desmond

Journal article  |  2019  |  Journal of Alzheimer's Disease

Ethical Issues in the Treatment of Late-Stage Alzheimer's Disease

Andrew D Watt, Nicole L Jenkins, Gawain McColl, Steven Collins, Patricia M Desmond

Journal article  |  2019  |  Journal of Alzheimer's Disease

Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease

Barbara R Cardoso, Blaine R Roberts, Charles B Malpas, Lucy Vivash, Sila Genc, Michael M Saling, Patricia Desmond, Christopher Steward, Rodney J Hicks, Jason Callahan, Amy Brodtmann, Steven Collins, Stephen Macfarlane, Niall M Corcoran, Christopher M Hovens, Dennis Velakoulis, Terence J O'Brien, Dominic J Hare, Ashley I Bush

Journal article  |  2019  |  NEUROTHERAPEUTICS

Creutzfeldt-Jakob disease surveillance in Australia: update to December 2016

Genevieve M Klug, Shannon Sarros, Christiane Stehmann, Marion Simpson, Catriona McLean, Colin L Masters, Steven J Collins

Journal article  |  2018  |  Communicable diseases intelligence

Reply.

RV Chandra, J Maingard, H Asadi, L-A Slater, JA Hirsch

Journal article  |  2018  |  American Journal of Neuroradiology

Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression

Steven J Collins, Carolin Tumpach, Bradley R Groveman, Simon C Drew, Cathryn L Haigh

Journal article  |  2018  |  Cellular and Molecular Life Sciences

Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species

Simote Totauhelotu Foliaki, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins

Journal article  |  2018  |  PLOS Pathogens

CSF Tau supplements 14-3-3 protein detection for sporadic Creutzfeldt-Jakob disease diagnosis while transitioning to next generation diagnostics

Qiao-Xin Li, Shiji Varghese, Shannon Sarros, Christiane Stehmann, James D Doecke, Christopher J Fowler, Colin L Masters, Steven J Collins

Journal article  |  2018  |  Journal of Clinical Neuroscience

Acute Neurotoxicity Models of Prion Disease

AMT Islam, PA Adlard, DI Finkelstein, V Lewis, S Biggi, E Biasini, SJ Collins

Journal article  |  2018  |  ACS Chemical Neuroscience

Iatrogenic Creutzfeldt-Jakob disease with Amyloid-beta pathology: an international study

Ignazio Cali, Mark L Cohen, Stephane Haik, Piero Parchi, Giorgio Giaccone, Steven J Collins, Diane Kofskey, Han Wang, Catriona A McLean, Jean-Philippe Brandel, Nicolas Privat, Veronique Sazdovitch, Charles Duyckaerts, Tetsuyuki Kitamoto, Ermias D Belay, Ryan A Maddox, Fabrizio Tagliavini, Maurizio Pocchiari, Ellen Leschek, Brian S Appleby, et al.

Journal article  |  2018  |  ACTA NEUROPATHOLOGICA COMMUNICATIONS

Concordance Between Cerebrospinal Fluid Biomarkers with Alzheimer's Disease Pathology Between Three Independent Assay Platforms

James D Doecke, Alan Rembach, Victor L Villemagne, Shiji Varghese, Stephanie Rainey-Smith, Shannon Sarros, Lisbeth A Evered, Christopher J Fowler, Kelly K Pertile, Rebecca L Rumble, Brett Trounson, Kevin Taddei, Simon M Laws, S Lance Macaulay, Ashley I Bush, Kathryn A Ellis, Ralph Martins, David Ames, Brendan Silbert, Hugo Vanderstichele, et al.

Journal article  |  2018  |  JOURNAL OF ALZHEIMERS DISEASE

In vivo prion models and the disconnection between transmissibility and neurotoxicity

Matteo Senesi, Victoria Lewis, Jee H Kim, Paul A Adlard, David I Finkelstein, Steven J Collins

Journal article  |  2017  |  Ageing Research Reviews

Oxidation of Iron under Physiologically Relevant Conditions in Biological Fluids from Healthy and Alzheimer's Disease Subjects

Linh Q Lam, Bruce X Wong, Tony Frugier, Qao-Xin Li, Steven J Collins, Ashley I Bush, Peter J Crack, James A Duce

Journal article  |  2017  |  ACS Chemical Neuroscience

Simplified Murine 3D Neuronal Cultures for Investigating Neuronal Activity and Neurodegeneration

Steven J Collins, Cathryn L Haigh

Journal article  |  2017  |  CELL BIOCHEMISTRY AND BIOPHYSICS

Prion Diseases

Benjamin C Whitechurch, Jeremy M Welton, Steven J Collins, Victoria A Lawson

Journal article  |  2017  |  Advances in neurobiology

Molecular Subtyping of PrPres in Human Sporadic CJD Brain Tissue

GM Klug, V Lewis, SJ Collins

Book Chapter  |  2017  |  Methods in Molecular Biology

RT-QuIC Assays in Humans … and Animals.

Steven Collins, Shannon Sarros

Journal article  |  2016  |  Food Safety

Prion diseases are neurodegenerative diseases affecting both humans and animal species. The phenotypic spectrum is broad and inclu..

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

Matthias Schmitz, Maria Cramm, Franc Llorens, Dominik Mueller-Cramm, Steven Collins, Ryuichiro Atarashi, Katsuya Satoh, Christina D Orru, Bradley R Groveman, Saima Zafar, Walter J Schulz-Schaeffer, Byron Caughey, Inga Zerr

Journal article  |  2016  |  Nature Protocols

CREUTZFELDT-JAKOB DISEASE SURVEILLANCE IN AUSTRALIA: UPDATE TO DECEMBER 2015

Genevieve M Klug, Alison Boyd, Shannon Sarros, Christiane Stehmann, Marion Simpson, Catriona McLean, Colin L Masters, Steven J Collins

Journal article  |  2016  |  Communicable diseases intelligence quarterly report

A 2-Substituted 8-Hydroxyquinoline Stimulates Neural Stem Cell Proliferation by Modulating ROS Signalling

Cathryn L Haigh, Carolin Tumpach, Steven J Collins, Simon C Drew

Journal article  |  2016  |  CELL BIOCHEMISTRY AND BIOPHYSICS

LGI1 antibody encephalopathy overlapping with sporadic Creutzfeldt-Jakob disease

Boaz Kim, Patrick Yoo, Tom Sutherland, Alison Boyd, Christiane Stehmann, Catriona McLean, Steven Collins

Journal article  |  2016  |  Neurology - Neuroimmunology Neuroinflammation

Cerebrospinal Fluid Real-Time Quaking-Induced Conversion Is a Robust and Reliable Test for Sporadic Creutzfeldt-Jakob Disease: An International Study

Lynne I McGuire, Anna Poleggi, Ilaria Poggiolini, Silvia Suardi, Katarina Grznarova, Song Shi, Bart de Vil, Shannon Sarros, Katsuya Satoh, Keding Cheng, Maria Cramm, Graham Fairfoul, Matthias Schmitz, Inga Zerr, Patrick Cras, Michele Equestre, Fabrizio Tagliavini, Ryuichiro Atarashi, David Knox, Steven Collins, et al.

Journal article  |  2016  |  Annals of Neurology

CREUTZFELDT-JAKOB DISEASE SURVEILLANCE IN AUSTRALIA: UPDATE TO DECEMBER 2014

Genevieve M Klug, Alison Boyd, Shannon Sarros, Christiane Stehmann, Marion Simpson, Catriona McLean, Colin L Masters, Steven J Collins

Journal article  |  2016  |  Communicable diseases intelligence quarterly report

Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic

Matthias Schmitz, Elisabeth Ebert, Katharina Stoeck, Andre Karch, Steven Collins, Miguel Calero, Theodor Sklaviadis, Jean-Louis Laplanche, Ewa Golanska, Ines Baldeiras, Katsuya Satoh, Raquel Sanchez-Valle, Anna Ladogana, Anders Skinningsrud, Anna-Lena Hammarin, Eva Mitrova, Franc Llorens, Yong Sun Kim, Alison Green, Inga Zerr

Journal article  |  2016  |  Molecular Neurobiology

Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease

Maria Cramm, Matthias Schmitz, Andre Karch, Eva Mitrova, Franziska Kuhn, Bjoern Schroeder, Alex Raeber, Daniela Varges, Yong-Sun Kim, Katsuya Satoh, Steven Collins, Inga Zerr

Journal article  |  2016  |  Molecular Neurobiology

Endoproteolytic cleavage as a molecular switch regulating and diversifying prion protein function

Cathryn L Haigh, Steven J Collins

Journal article  |  2016  |  Neural Regeneration Research

Prion protein "gamma-cleavage": characterizing a novel endoproteolytic processing event

Victoria Lewis, Vanessa A Johanssen, Peter J Crouch, Genevieve M Klug, Nigel M Hooper, Steven J Collins

Journal article  |  2016  |  CELLULAR AND MOLECULAR LIFE SCIENCES

Quantifying prion disease penetrance using large population control cohorts

Eric Vallabh Minikel, Sonia M Vallabh, Monkol Lek, Karol Estrada, Kaitlin E Samocha, J Fah Sathirapongsasuti, Cory Y McLean, Joyce Y Tung, Linda PC Yu, Pierluigi Gambetti, Janis Blevins, Shulin Zhang, Yvonne Cohen, Wei Chen, Masahito Yamada, Tsuyoshi Hamaguchi, Nobuo Sanjo, Hidehiro Mizusawa, Yosikazu Nakamura, Tetsuyuki Kitamoto, et al.

Journal article  |  2016  |  Science Translational Medicine

A Phase IIa Randomized Control Trial of VEL015 ( Sodium Selenate) in Mild-Moderate Alzheimer's Disease

Charles B Malpas, Lucy Vivash, Sila Genc, Michael M Saling, Patricia Desmond, Christopher Steward, Rodney J Hicks, Jason Callahan, Amy Brodtmann, Steven Collins, Stephen Macfarlane, Niall M Corcoran, Christopher M Hovens, Dennis Velakoulis, Terence J O'Brien

Journal article  |  2016  |  Journal of Alzheimer's Disease

High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease

Maxime Francois, Michael F Fenech, Philip Thomas, Maryam Hor, Alan Rembach, Ralph N Martins, Stephanie R Rainey-Smith, Colin L Masters, David Ames, Christopher C Rowe, S Lance Macaulay, Andrew F Hill, Wayne R Leifert

Journal article  |  2016  |  Current Alzheimer Research

Hyperekplexia as the presenting symptom of Creutzfeldt-Jakob disease.

Sudarshini Ramanathan, Victor SC Fung, Alen Bielich, Lynette Masters, Robert R Russo, Michael E Buckland, Shannon Sarros, Genevieve MJA Klug, Steven Collins, Stephen W Reddel

Journal article  |  2015  |  Neurology: Clinical Practice

Alzheimer's disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology

Alan Rembach, Lisbeth A Evered, Qiao-Xin Lii, Tabitha Nash, Lesley Vidaurre, Christopher J Fowler, Kelly K Pertile, Rebecca L Rumble, Brett O Trounson, Sarah Maher, Francis Mooney, Maree Farrow, Kevin Taddei, Stephanie Rainey-Smith, Simon M Laws, S Lance Macaulay, William Wilson, David G Darby, Ralph N Martins, David Ames, et al.

Journal article  |  2015  |  ALZHEIMERS RESEARCH & THERAPY

The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses

Cathryn L Haigh, Carolin Tumpach, Simon C Drew, Steven J Collins

Journal article  |  2015  |  PLOS ONE

Glycosaminoglycan sulfation determines the biochemical properties of prion protein aggregates

Laura J Ellett, Bradley M Coleman, Mitch C Shambrook, Vanessa A Johanssen, Steven J Collins, Colin L Masters, Andrew F Hill, Victoria A Lawson

Journal article  |  2015  |  GLYCOBIOLOGY

A Genome Wide Association Study Links Glutamate Receptor Pathway to Sporadic Creutzfeldt-Jakob Disease Risk

Pascual Sanchez-Juan, Matthew T Bishop, Gabor G Kovacs, Miguel Calero, Yurii S Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Angel Carracedo, Sven J van der Lee, Thomas Stroebel, Fernando Rivadeneira, Albert Hofman, Stephane Haik, Onofre Combarros, Jose Berciano, Andre G Uitterlinden, et al.

Journal article  |  2015  |  PLOS ONE

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro

Steven J Collins, Carolin Tumpach, Qiao-Xin Li, Victoria Lewis, Timothy M Ryan, Blaine Roberts, Simon C Drew, Victoria A Lawson, Cathryn L Haigh

Journal article  |  2015  |  STEM CELL RESEARCH & THERAPY

MEK1 transduces the prion protein N2 fragment antioxidant effects

CL Haigh, AR McGlade, SJ Collins

Journal article  |  2015  |  Cellular and Molecular Life Sciences

Alzheimer's Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-beta Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

Qiao-Xin Li, Victor L Villemagne, James D Doecke, Alan Rembach, Shannon Sarros, Shiji Varghese, Amelia McGlade, Katrina M Laughton, Kelly K Pertile, Christopher J Fowler, Rebecca L Rumble, Brett O Trounson, Kevin Taddei, Stephanie R Rainey-Smith, Simon M Laws, Joanne S Robertson, Lisbeth A Evered, Brendan Silbert, Kathryn A Ellis, Christopher C Rowe, et al.

Journal article  |  2015  |  Journal of Alzheimer's Disease

Neutron Reflectometry Studies Define Prion Protein N-terminal Peptide Membrane Binding

Anton P Le Brun, Cathryn L Haigh, Simon C Drew, Michael James, Martin P Boland, Steven J Collins

Journal article  |  2014  |  BIOPHYSICAL JOURNAL

Ascertainment Bias Causes False Signal of Anticipation in Genetic Prion Disease

Eric Vallabh Minikel, Inga Zerr, Steven J Collins, Claudia Ponto, Alison Boyd, Genevieve Klug, Andre Karch, Joanna Kenny, John Collinge, Leonel T Takada, Sven Forner, Jamie C Fong, Simon Mead, Michael D Geschwind

Journal article  |  2014  |  The American Journal of Human Genetics

Detection rates and phenotypic spectrum of m.3243A > G in the MT-TL1 gene: A molecular diagnostic laboratory perspective

J Chin, R Marotta, M Chiotis, EH Allan, SJ Collins

Journal article  |  2014  |  Mitochondrion

Antioxidant and Metal Chelation-Based Therapies in the Treatment of Prion Disease.

Marcus W Brazier, Anthony G Wedd, Steven J Collins

Journal article  |  2014  |  Antioxidants

Many neurodegenerative disorders involve the accumulation of multimeric assemblies and amyloid derived from misfolded conformers o..

C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to alpha-cleavage

Vanessa A Johanssen, Timothy Johanssen, Colin L Masters, Andrew F Hill, Kevin J Barnham, Steven J Collins

Journal article  |  2014  |  BIOCHEMICAL JOURNAL

Intensity of human prion disease surveillance predicts observed disease incidence

Genevieve MJA Klug, Handan Wand, Marion Simpson, Alison Boyd, Matthew Law, Colin L Masters, Radoslav Matej, Rachel Howley, Michael Farrell, Maren Breithaupt, Inga Zerr, Cornelia van Duijn, Carla Ibrahim-Verbaas, Jan Mackenzie, Robert G Will, Jean-Philippe Brandel, Annick Alperovitch, Herbert Budka, Gabor G Kovacs, Gerard H Jansen, et al.

Journal article  |  2013  |  Journal of Neurology, Neurosurgery and Psychiatry

Updated Creutzfeldt-Jakob disease infection control guidelines: sifting facts from fiction REPLY

Steven J Collins, Eugene Athan, Ann P Koehler

Journal article  |  2013  |  Medical Journal of Australia

Updated Creutzfeldt-Jakob disease infection control guidelines: sifting facts from fiction

Robert A Hodgson

Journal article  |  2013  |  Medical Journal of Australia

Unusual Clinical and Molecular-Pathological Profile of Gerstmann-Straussler-Scheinker Disease Associated With a Novel PRNP Mutation (V176G)

Marion Simpson, Vanessa Johanssen, Alison Boyd, Genevieve Klug, Colin L Masters, Qiao-Xin Li, Roger Pamphlett, Catriona McLean, Victoria Lewis, Steven J Collins

Journal article  |  2013  |  JAMA NEUROLOGY

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

Layla Sinclair, Victoria Lewis, Steven J Collins, Cathryn L Haigh

Journal article  |  2013  |  DISEASE MODELS & MECHANISMS

Surveillance for Creutzfeldt-Jakob disease in Australia: update to December 2012.

Genevieve M Klug, Alison Boyd, Teresa Zhao, Christiane Stehmann, Marion Simpson, Catriona A McLean, Colin L Masters, Steven J Collins

Journal article  |  2013  |  Communicable diseases intelligence quarterly report

Nation-wide surveillance for transmissible spongiform encephalopathies including Creutzfeldt-Jakob disease (CJD) is undertaken by ..

CSF biomarker variability in the Alzheimer's Association quality control program

Niklas Mattsson, Ulf Andreasson, Staffan Persson, Maria C Carrillo, Steven Collins, Sonia Chalbot, Neal Cutler, Diane Dufour-Rainfray, Anne M Fagan, Niels HH Heegaard, Ging-Yuek Robin Hsiung, Bradley Hyman, Khalid Iqbal, D Richard Lachno, Alberto Lleo, Piotr Lewczuk, Jose L Molinuevo, Piero Parchi, Axel Regeniter, Robert Rissman, et al.

Journal article  |  2013  |  Alzheimer's & Dementia

Immunotherapeutic approaches in prion disease: progress, challenges and potential directions.

Marcus W Brazier, Alexandra I Mot, Anthony R White, Steven J Collins

Journal article  |  2013  |  Therapeutic Delivery

Therapeutic trials utilizing animal models of prion disease have explored a variety of compounds and a number of approaches with v..

Sporadic CreutzfeldtJakob disease presenting as spastic paraparesis

N Geevasinga, NG Simon, S Collins, ME Buckland, K Ng

Journal article  |  2013  |  European Journal of Neurology

Updated Creutzfeldt-Jakob disease infection control guidelines: sifting facts from fiction

Ann P Koehler, Eugene Athan, Steven J Collins

Journal article  |  2013  |  Medical Journal of Australia

Characterising the uncommon corticobasal syndrome presentation of sporadic Creutzfeldt-Jakob disease

Will Lee, Marion Simpson, Helen Ling, Catriona Mclean, Steven Collins, David R Williams

Journal article  |  2013  |  PARKINSONISM & RELATED DISORDERS

The Prion Protein Preference of Sporadic Creutzfeldt-Jakob Disease Subtypes

Helen MJ Klemm, Jeremy M Welton, Colin L Masters, Genevieve M Klug, Alison Boyd, Andrew F Hill, Steven J Collins, Victoria A Lawson

Journal article  |  2012  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Surveillance of Creutzfeldt-Jakob disease in Australia: update to December 2011.

Genevieve M Klug, Alison Boyd, Amelia McGlade, Christiane Stehmann, Marion Simpson, Colin L Masters, Steven J Collins

Journal article  |  2012  |  Communicable diseases intelligence quarterly report

The Australian National Creutzfeldt-Jakob disease Registry (ANCJDR) is a Commonwealth Government-funded surveillance unit, respons..

A case of myelopathy, myopathy, peripheral neuropathy and subcortical grey matter degeneration associated with recessive compound heterozygous POLG1 mutations

P McKelvie, R Marotta, DR Thorburn, J Chin, S Punchihewa, S Collins

Journal article  |  2012  |  Neuromuscular Disorders

Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity

Victoria Lewis, Cathryn L Haigh, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins

Journal article  |  2012  |  MOLECULAR NEURODEGENERATION

Health professions and risk of sporadic Creutzfeldt-Jakob disease, 1965 to 2010

E Alcalde-Cabero, J Almazan-Isla, JP Brandel, M Breithaupt, J Catarino, S Collins, J Haybaeck, R Hoeftberger, E Kahana, GG Kovacs, A Ladogana, E Mitrova, A Molesworth, Y Nakamura, M Pocchiari, M Popovic, M Ruiz-Tovar, AL Taratuto, C van Duijn, M Yamada, et al.

Journal article  |  2012  |  Eurosurveillance

Examining C3 cleavage of the cellular prion protein

Victoria Lewis, Nigel Hooper, Steven Collins

Conference Proceedings  |  2012  |  PRION

Objective measurements of surveillance intensity predict disease incidence and guide ascertainment adequacy in sporadic Creutzfeldt-Jakob disease

Steven Collins, Genevieve Klug, Handan Wand, Marion Simpson, Alison Boyd, Matthew Law, Colin Masters, Radoslav Matej, Rachel Howley, Michael Farrell, Maren Breithaupt, Inga Zerr, Jan McKenzie, Robert Will, Jean-Philippe Brandel, Annick Alperovitch, Herbert Budka, Gabor Kovacs, Gerard Jansen, Michael Coulthard

Journal article  |  2012  |  PRION

Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

Victoria Lewis, Isobel J Whitehouse, Herbert Baybutt, Jean C Manson, Steven J Collins, Nigel M Hooper

Journal article  |  2012  |  PLOS ONE

Late-adult onset Leigh syndrome

Penelope McKelvie, Bernard Infeld, Rosetta Marotta, Judy Chin, David Thorburn, Steven Collins

Journal article  |  2012  |  Journal of Clinical Neuroscience

Generating recombinant C-terminal prion protein fragments of exact native sequence

VA Johanssen, KJ Barnham, CL Masters, AF Hill, SJ Collins

Journal article  |  2012  |  Neurochemistry International

A case of myelopathy, myopathy, peripheral neuropathy and subcortical grey matter degeneration associated with recessive compound heterozygous POLG1 mutations

P McKelvie, R Marotta, DR Thorburn, J Chin, S Punchihewa, S Collins

Journal article  |  2012  |  Neuromuscular Disorders

Microwave Synthesis of Prion Protein Fragments up to 111 Amino Acids in Length Generates Biologically Active Peptides

John A Karas, Martin Boland, Cathryn Haigh, Vanessa Johanssen, Andrew Hill, Kevin Barnham, Steven Collins, Denis Scanlon

Journal article  |  2012  |  International Journal of Peptide Research and Therapeutics

Misfolded conformers of the prion protein are aetiologically implicated in neurodegenerative conditions termed prion diseases (als..

Metal attenuating therapies in neurodegenerative disease

Alexandra I Mot, Anthony G Wedd, Layla Sinclair, David R Brown, Steven J Collins, Marcus W Brazier

Journal article  |  2011  |  Expert Review of Neurotherapeutics

Genetic prion disease-associated myelodysplasia and SIADH in siblings

FCF Chang, Y Berman, ME Buckland, N MacKinlay, A McGlade, S Collins, K Ng

Journal article  |  2011  |  European Journal of Neurology

Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro

Cathryn L Haigh, Amelia R McGlade, Victoria Lewis, Colin L Masters, Victoria A Lawson, Steven J Collins

Journal article  |  2011  |  Free Radical Biology and Medicine

SURVEILLANCE OF CREUTZFELDT-JAKOB DISEASE IN AUSTRALIA: UPDATE TO DECEMBER 2010

Genevieve M Klug, Alison Boyd, Amelia McGlade, Christiane Stehmann, Colin L Masters, Steven J Collins

Journal article  |  2011  |  Communicable diseases intelligence

Iatrogenic Creutzfeldt-Jakob disease in Australia: time to amend infection control measures for pituitary hormone recipients? REPLY

Alison Boyd, Genevieve MJA Klug, Colin L Masters, Steven J Collins

Journal article  |  2011  |  MEDICAL JOURNAL OF AUSTRALIA

Novel single base pair COX III subunit deletion of mitochondrial DNA associated with rhabdomyolysis

Rosetta Marotta, Judy Chin, Denise M Kirby, Maria Chiotis, Mark Cook, Steven J Collins

Journal article  |  2011  |  Journal of Clinical Neuroscience

Overview and recent advances in neuropathology. Part 2: Neurodegeneration

Colin L Masters, Jillian J Kril, Glenda M Halliday, Roger Pamphlett, Steven Collins, Andrew F Hill, Catriona McLean

Journal article  |  2011  |  Pathology

Optical Imaging Detects Apoptosis in the Brain and Peripheral Organs of Prion-Infected Mice

Simon C Drew, Cathryn L Haigh, Helen MJ Klemm, Colin L Masters, Steven J Collins, Kevin J Barnham, Victoria A Lawson

Journal article  |  2011  |  Journal of Neuropathology and Experimental Neurology

Novel single base pair COX III subunit deletion of mitochondrial DNA associated with rhabdomyolysis

R Marotta, J Chin, DM Kirby, M Chiotis, M Cook, SJ Collins

Journal article  |  2011  |  Journal of Clinical Neuroscience

Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion

Ryuichiro Atarashi, Katsuya Satoh, Kazunori Sano, Takayuki Fuse, Naohiro Yamaguchi, Daisuke Ishibashi, Takehiro Matsubara, Takehiro Nakagaki, Hitoki Yamanaka, Susumu Shirabe, Masahito Yamada, Hidehiro Mizusawa, Tetsuyuki Kitamoto, Genevieve Klug, Amelia McGlade, Steven J Collins, Noriyuki Nishida

Journal article  |  2011  |  Nature Medicine

Overview of the spectrum of human prion diseases

V LAWSON, SJ Collins

Book Chapter  |  2011

The Cellular and Molecular Biology of Prion Disease

VA Lawson, SJ Collins, undefined Haigh, undefined Lewis, V Wall, MW Brazier, S Hawke, RA Bessen, JC Bartz, AE Kincaid, LJ Vella, R Cappai, AF Hill, L Gadtke, G Lutzny, C Krammer, R Bester, I Vorberg, M Bishop, JM Welton, et al.

Book  |  2011

Near-Infrared Fluorescence Imaging of Apoptotic Neuronal Cell Death in a Live Animal Model of Prion Disease

Victoria A Lawson, Cathryn L Haigh, Blaine Roberts, Vijaya B Kenche, Helen MJ Klemm, Colin L Masters, Steven J Collins, Kevin J Barnham, Simon C Drew

Journal article  |  2010  |  ACS Chemical Neuroscience

14-3-3 protein detection and sporadic CJD: the status quo serves well while awaiting progress

Steven J Collins, Amelia McGlade, Alison Boyd, CL Masters, Genevieve MJA Klug

Journal article  |  2010  |  Journal of Neurology, Neurosurgery & Psychiatry

Anionic Phospholipid Interactions of the Prion Protein N Terminus Are Minimally Perturbing and Not Driven Solely by the Octapeptide Repeat Domain

Martin P Boland, Claire R Hatty, Frances Separovic, Andrew F Hill, Deborah J Tew, Kevin J Barnham, Cathryn L Haigh, Michael James, Colin L Masters, Steven J Collins

Journal article  |  2010  |  Journal of Biological Chemistry

latrogenic Creutzfeldt-Jakob disease in Australia: time to amend infection control measures for pituitary hormone recipients?

Alison Boyd, Genevieve MJA Klug, Lawrence B Schonberger, Amelia McGlade, Jean-Philippe Brandel, Colin L Masters, Steven J Collins

Journal article  |  2010  |  Medical Journal of Australia

Iatrogenic Creutzfeldt-Jakob disease in Australia: Time to amend infection control measures for pituitary hormone recipients?

A Boyd, GMJA Klug, LB Schonberger, A McGlade, JP Brandel, CL Masters, SJ Collins

Journal article  |  2010  |  Medical Journal of Australia

Glycosaminoglycan Sulphation Affects the Seeded Misfolding of a Mutant Prion Protein

Victoria A Lawson, Brooke Lumicisi, Jeremy Welton, Dorothy Machalek, Katrina Gouramanis, Helen M Klemm, James D Stewart, Colin L Masters, David E Hoke, Steven J Collins, Andrew F Hill

Journal article  |  2010  |  PLoS One

Manganese chelation therapy extends survival in a mouse model of M1000 prion disease

Marcus W Brazier, Irene Volitakis, Magda Kvasnicka, Anthony R White, John R Underwood, Jason E Green, Sen Han, Andrew F Hill, Colin L Masters, Steven J Collins

Journal article  |  2010  |  Journal of Neurochemistry

Copper, endoproteolytic processing of the prion protein and cell signalling

Cathryn Louise Haigh, Shai Y Marom, Steven John Collins

Journal article  |  2010  |  Frontiers in Bioscience

Surveillance of Creutzfeldt-Jakob disease in Australia: 2010 update.

Genevieve M Klug, Alison Boyd, Amelia McGlade, Christiane Stehmann, Colin L Masters, Steven J Collins

Journal article  |  2010  |  Communicable diseases intelligence

Surveillance of all human prion diseases in Australia has been the responsibility of the Australian National Creutzfeldt-Jakob Dis..

No evidence for prion protein gene locus multiplication in Creutzfeldt-Jakob disease

Steven J Collins, Maaike Schuur, Alison Boyd, Victoria Lewis, Genevieve M Klug, Amelia McGlade, Andrew van Oosterhout, Guido Breedveld, Ben A Oostra, Colin Masters, Cornelia M Van Duijn

Journal article  |  2010  |  Neuroscience Letters

Cellular roles of the prion protein in association with reggie/flotillin microdomains

Gonzalo P Solis

Journal article  |  2010  |  Frontiers in Bioscience

Surveillance of Creutzfeldt-Jakob disease in Australia: 2010 update

G KLUG, A BOYD, A McGLADE, C STEHMANN, M Masters, S COLLINS

Journal article  |  2010  |  Communicable Diseases Intelligence

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease

I Zerr, K Kallenberg, DM Summers, C Romero, A Taratuto, U Heinemann, M Breithaupt, D Varges, B Meissner, A Ladogana, M Schuur, S Haik, SJ Collins, Gerard H Jansen, GB Stokin, J Pimentel, E Hewer, D Collie, P Smith, H Roberts, et al.

Journal article  |  2009  |  Brain

Increased Proportions of C1 Truncated Prion Protein Protect Against Cellular M1000 Prion Infection

Victoria Lewis, Andrew F Hill, Cathryn L Haigh, Genevieve M Klug, Colin L Masters, Victoria A Lawson, Steven J Collins

Journal article  |  2009  |  Journal of Neuropathology and Experimental Neurology

PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site

Cathryn L Haigh, Victoria A Lewis, Laura J Vella, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins

Journal article  |  2009  |  Cell Research

Association of the MELAS m.3243A > G mutation with myositis and the superiority of urine over muscle, blood and hair for mutation detection

Rosetta Marotta, Katrina Reardon, Penny A McKelvie, Maria Chiotis, Judy Chin, Mark Cook, Steven J Collins

Journal article  |  2009  |  Journal of Clinical Neuroscience

C-11-PiB PET studies in typical sporadic Creutzfeldt-Jakob disease

VL Villemagne, CA McLean, K Reardon, A Boyd, V Lewis, G Klug, G Jones, D Baxendale, CL Masters, CC Rowe, SJ Collins

Journal article  |  2009  |  Journal of Neurology, Neurosurgery and Psychiatry

MRI lesion profiles in sporadic Creutzfeldt-Jakob disease

B Meissner, K Kallenberg, P Sanchez-Juan, D Collie, DM Summers, S Almonti, SJ Collins, P Smith, P Cras, GH Jansen, JP Brandel, MB Coulthart, H Roberts, B Van Everbroeck, D Galanaud, V Mellina, RG Will, I Zerr

Journal article  |  2009  |  Neurology

Surveillance of Creutzfeldt-Jakob disease in Australia: 2009 update.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Amelia McGlade, Christiane Stehmann, Colin L Masters, Steven J Collins

Journal article  |  2009  |  Communicable Diseases Intelligence

In Australia, the occurrence of all human transmissible spongiform encephalopathies (TSEs) is surveyed by the Australian National ..

The effects of prion protein expression on metal metabolism

Silvia Kralovicova, Sarah N Fontaine, Alexandra Alderton, Julia Alderman, K Vala Ragnarsdottir, Steven J Collins, David R Brown

Journal article  |  2009  |  Molecular and Cellular Neurosciences

Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response

Cathryn L Haigh, Simon C Drew, Martin P Boland, Colin L Masters, Kevin J Barnham, Victoria A Lawson, Steven J Collins

Journal article  |  2009  |  Journal of Cell Science

Enhanced geographically restricted surveillance simulates sporadic Creutzfeldt-Jakob disease cluster

Genevieve M Klug, Handan Wand, Alison Boyd, Matthew Law, Scott Whyte, John Kaldor, Colin L Masters, Steven Collins

Journal article  |  2009  |  Brain

Therapeutic interventions ameliorating prion disease

Marcus W Brazier, Vanessa A Wall, Barry W Brazier, Colin L Masters, Steven J Collins

Journal article  |  2009  |  EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease

Marcus W Brazier, Susan R Doctrow, Colin L Masters, Steven J Collins

Journal article  |  2008  |  Free Radical Biology and Medicine

Surveillance of Creutzfeldt-Jakob disease in Australia: 2008.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Amelia R McGlade, Helene Roberts, Samantha L Douglass, Colin L Masters, Steven J Collins

Journal article  |  2008  |  Communicable Diseases Intelligence

Australia-wide surveillance of all human transmissible spongiform encephalopathies (TSEs) is performed by the Australian National ..

Analysis of endogenous PrPC processing in neuronal and non-neuronal cell lines.

Victoria Lewis, Steven J Collins

Book Chapter  |  2008  |  Methods in Molecular Biology

Numerous transmembrane and glycosylphosphatidylinositol (GPI)-anchored proteins, covering a vast range of structural and functiona..

Analysis of endogenous PrPC processing in neuronal and non-neuronal cell lines

V Lewis, SJ Collins

Journal article  |  2008  |  Methods in Molecular Biology

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture

Victoria A Lawson, Laura J Velia, James D Stewart, Robyn A Sharples, Helen Klemm, Dorothy M Machalek, Colin L Masters, Roberto Cappai, Steven J Collins, Andrew F Hill

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.

V LAWSON, L VELLA, J STEWART, R SHARPLES, H KLEMM, D MACHALEK, C MASTERS, R Cappai, SJ Collins, A HILL

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

Molecular typing of PrPres in human sporadic CJD brain tissue

V Lewis, GM Klug, AF Hill, SJ Collins

Journal article  |  2008  |  Methods in Molecular Biology

Molecular typing of PrPres in human sporadic CJD brain tissue.

Victoria Lewis, Genevieve M Klug, Andrew F Hill, Steven J Collins

Book Chapter  |  2008  |  Methods in Molecular Biology

Within the spectrum of sporadic human transmissible spongiform encephalopathies (TSEs), there is considerable diversity of disease..

Creutzfeldt-Jakob disease: Australian surveillance update to March 2007.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Samantha L Douglass, Helene Roberts, Rebecca Argent, Colin L Masters, Steven J Collins

Journal article  |  2007  |  Communicable Diseases Intelligence

From October 1993, prospective, national surveillance of the rare class of neurodegenerative diseases known as transmissible spong..

Novel prion protein gene mutation presenting with subacute PSP-like syndrome

DB Rowe, V Lewis, M Needham, M Rodriguez, A Boyd, C McLean, H Roberts, CL Masters, SJ Collins

Journal article  |  2007  |  Neurology

Chronic wasting disease.

S COLLINS

Book Chapter  |  2007

Human transmissible spongiform encephalopathies in eleven countries: diagnostic pattern across time, 1993-2002

Jesus de Pedro-Cuesta, Markus Glatzel, Javier Almazan, Katharina Stoeck, Vittorio Mellina, Maria Puopolo, Maurizio Pocchiari, Inga Zerr, Hans A Kretszchmar, Jean-Philippe Brandel, Nicole Delasnerie-Laupretre, Annick Alperovitch, Cornelia Van Duijn, Pascual Sanchez-Juan, Steven Collins, Victoria Lewis, Gerard H Jansen, Michael B Coulthart, Ellen Gelpi, Herbert Budka, et al.

Journal article  |  2006  |  BMC Public Health

Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease

SJ Collins, P Sanchez-Juan, CL Masters, GM Klug, C van Duijn, A Poleggi, M Pocchiari, S Almonti, N Cuadrado-Corrales, J de Pedro-Cuesta, H Budka, E Gelpi, M Glatzel, M Tolnay, E Hewer, I Zerr, U Heinemann, HA Kretszchmar, GH Jansen, E Olsen, et al.

Journal article  |  2006  |  Brain

CSFBACE1 activity is increased in CJD and Alzheimer disease other dementias

RMD Holsinger, JS Lee, A Boyd, CL Masters, SJ Collins

Journal article  |  2006  |  Neurology

Correlative studies support lipid peroxidation is linked to PrPres propagation as art early primary pathogenic event in prion disease

MW Brazier, V Lewis, GD Ciccotosto, GM Klub, VA Lawson, R Cappai, JW Ironside, CL Masters, AF Hill, AR White, S Collins

Journal article  |  2006  |  Brain Research Bulletin

Creutzfeldt-Jakob disease: Australian surveillance update to December 2005.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Samantha L Douglass, Rebecca Argent, James S Lee, Colin L Masters, Steven J Collins, undefined Australian National Creutzfeldt-Jakob Disease Registry

Journal article  |  2006  |  Communicable Diseases Intelligence

Australia-wide prospective surveillance of human transmissible spongiform encephalopathies (TSEs) has been conducted by the Austra..

Surveillance and prevention of vCJD and BSE: the Australian perspective.

S COLLINS

Conference Proceedings  |  2006  |  Addressing foodborne threats to health: policies, practices and global coordination.

Detection of prion epitopes on PrPc and PrPsc of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP

FF Yuan, S Biffin, MW Brazier, M Suarez, R Cappai, AF Hill, SJ Collins, JS Sullivan, D Middleton, G Multhaup, AF Geczy, CL Masters

Journal article  |  2005  |  Immunology and Cell Biology

Ethical considerations in presymptomatic testing for variant CJD

RE Duncan, MB Delatycki, SJ Collins, A Boyd, CL Masters, J Savulescu

Journal article  |  2005  |  JOURNAL OF MEDICAL ETHICS

Genetic prion disease: the EUROCJD experience

GG Kovacs, M Puopolo, A Ladogana, M Pocchiari, H Budka, C van Duijn, SJ Collins, A Boyd, A Giulivi, M Coulthart, N Delasnerie-Laupretre, JP Brandel, I Zerr, HA Kretzschmar, J de Pedro-Cuesta, M Calero-Lara, M Glatzel, A Aguzzi, M Bishop, R Knight, et al.

Journal article  |  2005  |  Human Genetics

Extended period of asymptomatic prion disease after low dose inoculation: Assessment of detection methods and implications for infection control

SJ Collins, V Lewis, MW Brazier, AF Hill, VA Lawson, GM Klug, CL Masters

Journal article  |  2005  |  Neurobiology of Disease

Identification of host factors that affect the formation of the protease resistant form of the prion protein

VA Lawson, JD Stewart, DA Machalek, SJ Collins, CL Masters, AF Hill

Conference Proceedings  |  2005  |  JOURNAL OF NEUROCHEMISTRY

Investigations into the propagation and spread of infectious prions in cultured cells

AF Hill, LJ Vella, RA Sharples, VA Lawson, SJ Collins, R Cappai, CL Masters

Conference Proceedings  |  2005  |  JOURNAL OF NEUROCHEMISTRY

Australian sporadic CJD analysis supports endogenous determinants of molecular-clinical profiles

V Lewis, AF Hill, GM Klug, A Boyd, CL Masters, SJ Collins

Journal article  |  2005  |  Neurology

Proteomic investigation into the propagation and spread of infectious prions in non-neuronal cells.

LJ Vella, RA Sharples, VA Lawson, SJ Collins, CL Masters, R Cappai, AF Hill

Conference Proceedings  |  2005  |  FEBS JOURNAL

Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada

A Ladogana, M Puopolo, EA Croes, H Budka, C Jarius, S Collins, GM Klug, T Sutcliffe, A Giulivi, A Alperovitch, N Delasnerie-Laupretre, JP Brandel, S Poser, H Kretzschmar, I Rietveld, E Mitrova, JD Cuesta, P Martinez-Martin, M Glatzel, A Aguzzi, et al.

Journal article  |  2005  |  Neurology

Prion protein glycosylation

VA Lawson, SJ Collins, CL Masters, AF Hill

Journal article  |  2005  |  Journal of Neurochemistry

Creutzfeldt-Jakob disease: Australian surveillance update to 31 December 2004.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Madga Kvasnicka, James S Lee, Colin L Masters, Steven J Collins

Journal article  |  2005  |  Communicable Diseases Intelligence

The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) was established in October 1993 after the identification of pr..

Biochemical analysis of peripheral tissue involvement in transmissible spongiform encephalopathies

VA Lawson, AF Hill, V Lewis, R Sharples, S Collins, CL Masters

Conference Proceedings  |  2005  |  Prions: Food and Drug Safety

Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies

M Pocchiari, M Puopolo, EA Croes, H Budka, E Gelpi, S Collins, V Lewis, T Sutcliffe, A Guilivi, N Delasnerie-Laupretre, JP Brandel, A Alperovitch, I Zerr, S Poser, HA Kretzschmar, A Ladogana, I Rietvald, E Mitrova, P Martinez-Martin, J de Pedro-Cuesta, et al.

Journal article  |  2004  |  Brain

SIRNA and antisense RNA mediated knockdown of mammalian PrP expression

AF Hill, H Sen, AR White, R Sharples, S Patrick, SJ Collins, R Cappai, CL Masters

Conference Proceedings  |  2004  |  Neurobiology of Aging

Increased beta-secretase activity in cerebrospinal fluid of Alzheimer's disease subjects

RMD Holsinger, CA McLean, SJ Collins, CL Masters, GV Evin

Journal article  |  2004  |  Annals of Neurology

Lyodura use and the risk of iatrogenic Creutzfeldt-Jakob disease in Australia

FJ Brooke, A Boyd, GM Klug, CL Masters, SJ Collins

Journal article  |  2004  |  Medical Journal of Australia

Transmissible spongiform encephalopathies

SJ Collins, VA Lawson, CL Masters

Journal article  |  2004  |  The Lancet

Miyoshi myopathy - an unusual cause of calf pain and tightness

KE Fallon, SJ Collins, C Purdam

Journal article  |  2004  |  Clinical Journal of Sport Medicine

Diagnostic screening of mitochondrial DNA mutations in Australian adults 1990-2001

R Marotta, J Chin, A Quigley, S Katsabanis, R Kapsa, E Byrne, S Collins

Journal article  |  2004  |  Internal Medicine Journal

Creutzfeldt-Jakob disease surveillance in Australia

GMJ KLUG, V LEWIS, A BOYD, JS LEE, CL MASTERS, SJ COLLINS

Journal article  |  2004  |  Communicable Diseases Intelligence

Structural biology of prions.

Roberto Cappai, Steven J Collins

Book Chapter  |  2004  |  Contributions to Microbiology

Human prion diseases: cause, clinical and diagnostic aspects.

Richard Knight, Marcus Brazier, Steven J Collins

Book Chapter  |  2004  |  Contributions to Microbiology

Novel prion protein insert mutation associated with prolonged neurodegenerative illness

V Lewis, S Collins, AF Hill, A Boyd, CA McLean, M Smith, CL Masters

Journal article  |  2003  |  Neurology

Organ distribution of prion proteins in variant Creutzfeldt-Jakob disease

I Ramasamy, M Law, S Collins, F Brooke

Journal article  |  2003  |  The Lancet Infectious Diseases

Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation

AR White, F Maher, MW Brazier, MF Jobling, J Thyer, LR Stewart, A Thompson, R Gibson, CL Masters, G Multhaup, K Beyreuther, CJ Barrow, SJ Collins, R Cappai

Journal article  |  2003  |  Brain Research

Variant Creutzfeldt-Jakob disease and the potential for its accidental transmission following surgery with contaminated instruments: The risk of transmission in Australia

I Ramasamy, M Law, S Collins, F Brooke

Journal article  |  2003  |  Folia Neuropathologica

Apparently sporadic CJD and covert health-care transmissions

V Lewis, A Boyd, CL Masters, SJ Collins

Journal article  |  2002  |  The Lancet Neurology

Creutzfeldt-Jakob disease in Australia 1970-1999

S Collins, A Boyd, JS Lee, V Lewis, A Fletcher, CA McLean, M Law, J Kaldor, MJ Smith, CL Masters

Journal article  |  2002  |  Neurology

Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model

SJ Collins, V Lewis, M Brazier, AF Hill, A Fletcher, CL Masters

Journal article  |  2002  |  Annals of Neurology

Paclitaxel plus carboplatin versus standard chemotherapy with either single-agent carboplatin or cyclophosphamide, doxorubicin, and cisplatin in women with ovarian cancer: the ICON3 randomised trial.

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Journal article  |  2002  |  The Lancet

BACKGROUND: Previously, we have shown that the combination of cyclophosphamide, doxorubicin, and cisplatin (CAP) and single-agent ..

Prions in skeletal muscle

MW Brazier, R Cappai, SJ Collins

Journal article  |  2002  |  Australian Veterinary Journal

Creutzfeldt-Jakob disease cluster in an Australian rural city

S Collins, A Boyd, A Fletcher, J Kaldor, A Hill, S Farish, C McLean, Z Ansari, M Smith, CL Masters

Journal article  |  2002  |  Annals of Neurology

Meningoencephalomyelitis with vasculitis due to varicella zoster virus: A case report and review of the literature

PA McKelvie, S Collins, D Thyagarajan, N Trost, H Sheorey, E Byrne

Journal article  |  2002  |  Pathology

Variant Creutzfeldt-Jakob disease: where are we?

SJ COLLINS

Journal article  |  2002  |  Microbiology Australia

Classical and variant Creutzfeldt-Jakob diseases and their potential impact on the practice of clinical dentistry in Australia

SWY Chan, S Collins, CL Masters, DM Walker

Journal article  |  2001  |  Australian Dental Journal

Transmissible spongiform encephalopathies in Australia.

A Boyd, A Fletcher, JS Lee, V Lewis, CL Masters, SJ Collins

Journal article  |  2001  |  Communicable Diseases Intelligence

The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) commenced surveillance in September 1993 as part of the Common..

Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126

LR Stewart, AR White, MF Jobling, BE Needham, F Maher, J Thyer, K Beyreuther, CL Masters, SJ Collins, R Cappai

Journal article  |  2001  |  Journal of Neuroscience Research

Gerstmann-Straussier-Scheinker syndrome, fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies

S Collins, CA McLean, CL Masters

Journal article  |  2001  |  Journal of Clinical Neuroscience

Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126

MF Jobling, XD Huang, LR Stewart, KJ Barnham, C Curtain, I Volitakis, M Perugini, AR White, RA Cherny, CL Masters, CJ Barrow, SJ Collins, AI Bush, R Cappai

Journal article  |  2001  |  Biochemistry

Muscle pain and cramps

K Reardon, S Collins, E Byrne

Journal article  |  2001  |  Medicine Today

Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons

AR White, R Guirguis, MW Brazier, MF Jobling, AF Hill, K Beyreuther, CJ Barrow, CL Masters, SJ Collins, R Cappai

Journal article  |  2001  |  Neurobiology of Disease

Human prion diseases: cause, clinical and diagnostic aspects.

R Knight, S Collins

Book Chapter  |  2001  |  Contributions to Microbiology

Structural biology of prions.

R Cappai, MF Jobling, CJ Barrow, S Collins

Book Chapter  |  2001  |  Contributions to Microbiology

'Mad cows' and variant Creutzfeldt-Jakob Disease (vCJD)

SJ COLLINS

Journal article  |  2001  |  Microbiology Australia

Iatrogenic Creutzfeldt-Jakob disease at the millennium

P Brown, M Preece, JP Brandel, T Sato, L McShane, I Zerr, A Fletcher, RG Will, M Pocchiari, NR Cashman, JH d'Aignaux, L Cervenakova, J Fradkin, LB Schonberger, SJ Collins

Journal article  |  2000  |  Neurology

Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt-Jakob disease.

I Zerr, M Pocchiari, S Collins, JP Brandel, J de Pedro Cuesta, RS Knight, H Bernheimer, F Cardone, N Delasnerie-Lauprêtre, N Cuadrado Corrales, A Ladogana, M Bodemer, A Fletcher, T Awan, A Ruiz Bremón, H Budka, JL Laplanche, RG Will, S Poser

Journal article  |  2000  |  Neurology

OBJECTIVE: To improve diagnostic criteria for sporadic Creutzfeldt-Jakob disease (CJD). METHODS: Pooled data on initial and final ..

Novel prion protein gene mutation in an octogenarian with Creutzfeldt-Jakob disease

S Collins, A Boyd, A Fletcher, K Byron, C Harper, CA McLean, CL Masters

Journal article  |  2000  |  Archives of Neurology

Creutzfeldt-Jakob disease: diagnostic utility of 14-3-3 protein immunodetection in cerebrospinal fluid

S Collins, A Boyd, A Fletcher, M Gonzales, CA McLean, K Byron, CL Masters

Journal article  |  2000  |  Journal of Clinical Neuroscience

Recent advances in the pre-mortem diagnosis of Creutzfeldt-Jakob disease

S Collins, A Boyd, A Fletcher, MF Gonzales, CA McLean, CL Masters

Journal article  |  2000  |  Journal of Clinical Neuroscience

Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity

AR White, SJ Collins, F Maher, MF Jobling, LR Stewart, JM Thyer, K Beyreuther, CL Masters, R Cappai

Journal article  |  1999  |  The American Journal of Pathology

The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126

MF Jobling, LR Stewart, AR White, C McLean, A Friedhuber, F Maher, K Beyreuther, CL Masters, CJ Barrow, SJ Collins, R Cappai

Journal article  |  1999  |  Journal of Neurochemistry

Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease.

A Alperovitch, I Zerr, M Pocchiari, E Mitrova, J de Pedro Cuesta, I Hegyi, S Collins, H Kretzschmar, C van Duijn, RG Will

Journal article  |  1999  |  The Lancet

Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: Implications for the mechanism of prion formation

R Cappai, L Stewart, MF Jobling, JM Thyer, AR White, K Beyreuther, SJ Collins, CL Masters, CJ Barrow

Journal article  |  1999  |  Biochemistry

The synthesis and spectroscopic analysis of the neurotoxic prion peptide 106-126: Comparative use of manual Boc and Fmoc chemistry

MF Jobling, CJ Barrow, AR White, CL Masters, SJ Collins, R Cappai

Journal article  |  1999  |  Letters in Peptide Science

Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study

S Collins, MG Law, A Fletcher, A Boyd, J Kaldor, CL Masters

Journal article  |  1999  |  The Lancet

Idiopathic granulomatous myositis: Does the clinical spectrum include polymyalgia rheumatica?

S Collins, P McKelvie, X Dennett, E Byrne

Journal article  |  1999  |  Journal of Clinical Neuroscience

The synthesis and spectroscopic analysis of the neurotoxic prion peptide 106-126: Comparative use of manual Boc and Fmoc chemistry

MF Jobling, CJ Barrow, AR White, CL Masters, SJ Collins, R Cappai

Journal article  |  1999  |  International Journal of Peptide Research and Therapeutics

Psychosocial and neuropsychological outcomes in two high-functioning males 20 years after traumatic brain injury

FJ Bardenhagen, SC Bowden, RB Shields, V McKay, PJ Smith, S Vogrin, SJ Collins, MJ Cook

Journal article  |  1999  |  Neurocase

McArdle's disease resembling an inflammatory myopathy

T O'Brien, S Collins, X Dennett, E Byrne, P McKelvie

Journal article  |  1998  |  Journal of Clinical Neuroscience

Novel measurement for automated interference pattern analysis of the diaphragm.

SJ Collins, RE Chen, H Remtulla, A Parkes, CF Bolton

Journal article  |  1997  |  Muscle & Nerve

The automated interference pattern analysis for limb muscles was modified to take into account the unique features of the needle E..

Are mitochondrial DNA deletions causative in chronic progressive external ophthalmoplegia patients?

MJB Jean-Francois, S Collins, N Kotsimbos, X Dennett, E Byrne

Journal article  |  1997  |  Journal of Clinical Neuroscience

Iatrogenic and zoonotic Creutzfeldt-Jakob disease: The Australian perspective

S Collins, CL Masters

Journal article  |  1996  |  Medical Journal of Australia

Iatrogenic and zoonotic Creutzfeldt-Jakob disease: the Australian perspective.

S Collins, CL Masters

Journal article  |  1996  |  Medical Journal of Australia

The transmissible brain diseases of humans and animals, the spongiform encephalopathies, continue to stimulate interest, and the a..

Recent developments in the transmissible spongiform encephalopathies: Implications for clinical practice

SJ Collins, R Cappai, CL Masters

Journal article  |  1996  |  Journal of Clinical Neuroscience

Needle EMG of the human diaphragm: power spectral analysis in normal subjects.

R Chen, SJ Collins, H Remtulla, A Parkes, CF Bolton

Journal article  |  1996  |  Muscle & Nerve

Needle EMG of the diaphragm was performed in 43 diaphragms in 23 healthy volunteers. The mean +/- standard deviation for the media..

Respiratory chain encephalomyopathies: a diagnostic classification.

UA Walker, S Collins, E Byrne

Journal article  |  1996  |  European Neurology

Mitochondrial encephalomyopathies are a heterogenous group of disorders with various biochemical defects of the respiratory chain ..

Expression of candidate pro-GnRH processing enzymes in rat hypothalamus and an immortalized hypothalamic neuronal cell line.

WC Wetsel, Z Liposits, NG Seidah, S Collins

Journal article  |  1995  |  Neuroendocrinology

Since gonadotropin-releasing hormone (GnRH, also referred to as LHRH) is a major hormone regulating mammalian reproduction, identi..

Contrasting histochemical features of various mitochondrial syndromes.

S Collins, E Byrne, X Dennett

Journal article  |  1995  |  Acta Neurologica Scandinavica

A comparative histochemical analysis of the prevalence and cytochrome oxidase staining characteristics of ragged-red fibres in lim..

Phrenic nerve conduction study in normal subjects.

R Chen, S Collins, H Remtulla, A Parkes, CF Bolton

Journal article  |  1995  |  Muscle & Nerve

Phrenic nerve conduction studies were performed in 50 phrenic nerves from 25 normal subjects using a technique modified from previ..

Transmissibility of Creutzfeldt-Jakob disease and related disorders.

SJ Collins, CL Masters

Journal article  |  1995  |  Science progress

The spongiform encephalopathies occur in both animals and humans, with kuru, Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Schei..

Biochemical and molecular investigation of mitochondrial disease: an illustrative case showing the value of a multifaceted approach.

E Byrne, B Jean-Francois, D Thyagarajan, S Collins, X Dennett, S Marzuki

Journal article  |  1991  |  Australian and New Zealand Journal of Medicine

Detailed biochemical and molecular investigations in a patient with Kearns-Sayre syndrome are presented. Polarographic studies in ..

Mitochondrial genome distribution in histochemically cytochrome c oxidase-negative muscle fibres in patients with a mixture of deleted and wild type mitochondrial DNA.

S Collins, C Rudduck, S Marzuki, X Dennett, E Byrne

Journal article  |  1991  |  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

In situ hybridization studies were performed on a series of chronic progressive external ophthalmoplegia patients harbouring large..

Chronic progressive external ophthalmoplegia in patients with large heteroplasmic mitochondrial DNA deletions: an immunocytochemical study.

S Collins, X Dennett, E Byrne, S Marzuki

Journal article  |  1991  |  Acta Neuropathologica

Immunocytochemical studies with a holocomplex antibody battery in patients with chronic progressive external ophthalmoplegia, with..