Steven Collins

Elevated levels of synaptic protein GAP‐43 associate with brain tauopathy, atrophy and cognition in Alzheimer’s disease

Kunal Dhiman, Victor LL Villemagne, Dhamidhu Eratne, Petra L Graham, Christopher J Fowler, Pierrick Bourgeat, Qiao‐Xin Li, Steven Collins, Ashley I Bush, Christopher C Rowe, David Ames, Colin L Masters, Kaj Blennow, Henrik Zetterberg, Ralph N Martins, Veer Bala Gupta

Journal article  |  2020  |  Alzheimer's & Dementia

Intra-cerebral haemorrhage but not neurodegenerative disease appears over-represented in deaths of Australian cadaveric pituitary hormone recipients (vol 81, pg 78, 2020)

Sultan H Alnakhli, Handan Wand, Matthew Law, Shannon Sarros, Christiane Stehmann, Matteo Senesi, Genevieve M Klug, Marion Simpson, Victoria Lewis, Colin L Masters, Steven J Collins

Journal article  |  2020  |  Journal of Clinical Neuroscience

Intra-cerebral haemorrhage but not neurodegenerative disease appears over-represented in deaths of Australian cadaveric pituitary hormone recipients

Sultan H Alnakhli, Handan Wand, Matthew Law, Shannon Sarros, Christiane Stehmann, Matteo Senesi, Genevieve M Klug, Marion Simpson, Victoria Lewis, Colin L Masters, Steven J Collins

Journal article  |  2020  |  Journal of Clinical Neuroscience

BACKGROUND AND PURPOSE: Recent scientific reports and epidemiological studies have engendered mounting concerns regarding the pote..

Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study

Emma Jones, Holger Hummerich, Emmanuelle Vir, James Uphill, Athanasios Dimitriadis, Helen Speedy, Tracy Campbell, Penny Norsworthy, Liam Quinn, Jerome Whitfield, Jacqueline Linehan, Zane Jaunmuktane, Sebastian Brandner, Parmjit Jat, Akin Nihat, Tze How Mok, Parvin Ahmed, Steven Collins, Christiane Stehmann, Shannon Sarros, et al.

Journal article  |  2020  |  The Lancet Neurology

BACKGROUND: Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common being sporadic Cr..

Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture

Qian Zhang, Julia Sidorenko, Baptiste Couvy-Duchesne, Riccardo E Marioni, Margaret J Wright, Alison M Goate, Edoardo Marcora, Kuan-lin Huang, Tenielle Porter, Simon M Laws, Perminder S Sachdev, Karen A Mather, Nicola J Armstrong, Anbupalam Thalamuthu, Henry Brodaty, Loic Yengo, Jian Yang, Naomi R Wray, Allan F McRae, Peter M Visscher

Journal article  |  2020  |  Nature Communications

Genetic association studies have identified 44 common genome-wide significant risk loci for late-onset Alzheimer's disease (LOAD)...

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2019.

Christiane Stehmann, Matteo Senesi, Shannon Sarros, Amelia McGlade, Marion Simpson, Genevieve Klug, Catriona McLean, Colin L Masters, Steven Collins

Journal article  |  2020  |  Communicable Diseases Intelligence

Nationwide surveillance of Creutzfeldt-Jakob disease and other human prion diseases is performed by the Australian National Creutz..

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December

Christiane Stehmann, Matteo Senesi, Shannon Sarros, Amelia McGlade, Marion Simpson, Genevieve Klug, Catriona McLean, Colin L Masters, Steven Collins

Journal article  |  2020  |  Communicable Diseases Intelligence Quarterly Report

Decreased cerebrospinal fluid neuronal pentraxin receptor is associated with PET-A beta load and cerebrospinal fluid A beta in a pilot study of Alzheimer's disease

Bryant Lim, Christopher Fowler, Qiao-Xin Li, Christopher Rowe, Kunal Dhiman, Veer Bala Gupta, Colin L Masters, James D Doecke, Ralph N Martins, Steven Collins, Eleftherios P Diamandis

Journal article  |  2020  |  Neuroscience Letters

Multifactorial pathological processes of Alzheimer's disease (AD) begin decades prior to clinical onset. Early identification of p..

PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity

Simote T Foliaki, Victoria Lewis, Abu MT Islam, Matteo Senesi, David Finkelstein, Laura J Ellett, Victoria A Lawson, Paul A Adlard, Blaine R Roberts, Steven J Collins

Journal article  |  2020  |  Biophysical Journal

Prion diseases are neurodegenerative disorders pathogenically linked to cellular prion protein (PrPC) misfolding into abnormal con..

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease

Sonia M Vallabh, Eric Vallabh Minikel, Victoria J Williams, Becky C Carlyle, Alison J McManus, Chase D Wennick, Anna Bolling, Bianca A Trombetta, David Urick, Chloe K Nobuhara, Jessica Gerber, Holly Duddy, Ingolf Lachmann, Christiane Stehmann, Steven J Collins, Kaj Blennow, Henrik Zetterberg, Steven E Arnold

Journal article  |  2020  |  BMC Medicine

BACKGROUND: Prion disease is neurodegenerative disease that is typically fatal within months of first symptoms. Clinical trials in..